keyword
MENU ▼
Read by QxMD icon Read
search

rheumatoid, arthritis, sle, scleroderma,

keyword
https://www.readbyqxmd.com/read/27909085/a-negative-antinuclear-antibody-does-not-indicate-autoantibody-negativity-in-myositis-role-of-anticytoplasmic-antibody-as-a-screening-test-for-antisynthetase-syndrome
#1
Rohit Aggarwal, Namrata Dhillon, Noreen Fertig, Diane Koontz, Zengbiao Qi, Chester V Oddis
OBJECTIVE: To evaluate the utility of anticytoplasmic autoantibody (anti-CytAb) in antisynthetase antibody-positive (anti-SynAb+) patients. METHODS: Anti-SynAb+ patients were evaluated for antinuclear antibody (ANA) and anti-CytAb [cytoplasmic staining on indirect immunofluorescence (IIF)] positivity. Anti-SynAb+ patients included those possessing anti-Jo1 and other antisynthetase autoantibodies. Control groups included scleroderma, systemic lupus erythematosus, Sjögren syndrome, rheumatoid arthritis, and healthy subjects...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27833788/vasculitic-diseases-and-prothrombotic-states-contributing-to-delayed-healing-in-chronic-wounds
#2
Victoria K Shanmugam
PURPOSE: Autoimmune diseases are a common cause of delayed wound healing and should be considered in patients with chronic wounds who do not respond to local wound care or who fail skin grafting in the absence of infection. RECENT FINDINGS: Epidemiologic studies have shown that, of patients with chronic wounds evaluated in specialized wound healing clinics, 20-23% have autoimmune etiologies for their wounds including vasculitis, rheumatoid arthritis, systemic lupus erythematosus, scleroderma, pyoderma gangrenosum and other autoimmune diseases...
December 2016: Current Dermatology Reports
https://www.readbyqxmd.com/read/27756248/the-impact-of-unrecognized-autoimmune-rheumatic-diseases-on-the-incidence-of-preeclampsia-and-fetal-growth-restriction-a-longitudinal-cohort-study
#3
Arsenio Spinillo, Fausta Beneventi, Elena Locatelli, Vèronique Ramoni, Roberto Caporali, Claudia Alpini, Giulia Albonico, Chiara Cavagnoli, Carlomaurizio Montecucco
BACKGROUND: The burden of pregnancy complications associated with well defined, already established systemic rheumatic diseases preexisting pregnancy such as rheumatoid arthritis, systemic lupus erythematosus or scleroderma is well known. Systemic rheumatic diseases are characterized by a long natural history with few symptoms, an undifferentiated picture or a remitting course making difficult a timely diagnosis. It has been suggested that screening measures for these diseases could be useful but the impact of unrecognized systemic rheumatic disorders on pregnancy outcome is unknown...
October 18, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27754164/sy-11-4-connective-tissue-disease-and-its-association-with-arterial-hypertension
#4
Michael J Ryan
Connective tissue diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis, and scleroderma, have a strong predilection for women and are associated with a marked increase in the prevalence of hypertension. The mechanisms leading to the increased risk of hypertension in these patients remain unclear; however, they are likely related to immune mediated changes in cardiovascular and renal function. Over the past several years, we have elucidated a number of factors that contribute to the development of hypertension during SLE using a widely established experimental model of SLE, the female NZBWF1 mouse...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643119/sy-11-4-connective-tissue-disease-and-its-association-with-arterial-hypertension
#5
Michael J Ryan
Connective tissue diseases including systemic lupus erythematosus (SLE), rheumatoid arthritis, and scleroderma, have a strong predilection for women and are associated with a marked increase in the prevalence of hypertension. The mechanisms leading to the increased risk of hypertension in these patients remain unclear; however, they are likely related to immune mediated changes in cardiovascular and renal function. Over the past several years, we have elucidated a number of factors that contribute to the development of hypertension during SLE using a widely established experimental model of SLE, the female NZBWF1 mouse...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27598847/ophthalmic-manifestations-in-chronic-inflammatory-rheumatic-diseases-at-a-referral-hospital-of-yaounde-cameroon
#6
Christelle Domngang Noche, Giles Kagmeni, Viola Dohvoma, Assumpta Lucienne Bella, Come Ebana Mvogo, Madeleine Singwe-Ngandeu
PURPOSE: To determine the profile of ophthalmic manifestations in chronic inflammatory rheumatic diseases (CIRD). METHODS: Observational study at the Yaounde Central Hospital and Innel Medical Centre (2004 to 2012). RESULTS: The study population (n = 36) consisted of 14 men and 22 women with average age of 47.9 ± 17.2 years. Cases of CIRD were rheumatoid arthritis (n = 16), systemic lupus erythematosus (n = 8), ankylosing spondylitis (n = 8), mixed connective tissue disease (n = 2), scleroderma (n = 1), and juvenile idiopathic arthritis (n = 1)...
September 6, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27590658/incidence-of-autoimmune-diseases-in-a-nationwide-hiv-aids-patient-cohort-in-taiwan-2000-2012
#7
Yung-Feng Yen, Pei-Hung Chuang, I-An Jen, Marcelo Chen, Yu-Ching Lan, Yen-Ling Liu, Yun Lee, Yen-Hsu Chen, Yi-Ming Arthur Chen
OBJECTIVES: It is not known if the incidences of autoimmune diseases are higher in individuals living with HIV infection or AIDS. Our study investigated the incidences of autoimmune diseases among people living with HIV/AIDS (PLWHA) in Taiwan during 2000-2012. METHODS: The Taiwan National Health Insurance Research Database was used to identify PLWHA. The incidence densities of systemic and organ-specific autoimmune diseases were calculated, and age-adjusted, sex-adjusted and period-adjusted standardised incidence rates (SIRs) were obtained by using two million people from the general population as controls...
September 2, 2016: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/27585081/autoimmune-swallowing-disorders
#8
Janine Amos, Anthony Baron, Adam D Rubin
PURPOSE OF REVIEW: Dysphagia can be the presenting symptom of autoimmune disease. The otolaryngologist should be familiar with and consider these disorders when assessing the patient with swallowing difficulties. RECENT FINDINGS: The present review gives a brief overview of Sjogren's syndrome, granulomatosis with polyangiitis, pemphigus and pemphigoid, rheumatoid arthritis, systemic lupus erythematosus, scleroderma and inflammatory myopathies, and how they affect swallowing...
August 31, 2016: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/27548651/myopathy-in-scleroderma-and-in-other-connective-tissue-diseases
#9
Julie J Paik
PURPOSE OF REVIEW: This review discusses the most updated literature of myopathy in scleroderma and other connective tissue diseases. RECENT FINDINGS: In the past year, studies have demonstrated that myopathy in scleroderma is associated with poor outcomes such as disability and mortality. In addition, muscle histopathology in scleroderma continues to reveal that it is a heterogeneous entity, and that necrosis and acute neurogenic atrophy may be a more prevalent histopathologic feature in muscle biopsies than previously reported...
November 2016: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/27225012/comparison-of-screening-dilution-and-automated-reading-for-antinuclear-antibody-detection-on-hep2-cells-in-the-monitoring-of-connective-tissue-diseases
#10
Anne E Depincé-Berger, Amelie Moreau, Virginie Bossy, Christian Genin, Melanie Rinaudo, Stephane Paul
BACKGROUND: Indirect immunofluorescence plays a major role in the detection of antinuclear antibodies (ANAs) and follow-up of their titers in the context of connective tissue diseases. Given the numerous unfavorable features of the conventional manual reading of HEP2 slides (need of time and expert morphologists for the reading, lack of standardization, subjectivity of the interpretation), the biomedical industry has developed automated techniques of slide preparation and microscope reading...
September 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27183937/burden-of-rheumatological-disorders-in-a-tertiary-care-hospital
#11
Tasnim Ahsan, Danish Khowaja, Rukhshanda Jabeen, Uzma Erum, Hassan Ali, Muhammad Umar Farooq, Urooj Lal Rehman
OBJECTIVE: T To evaluate the frequency of different rheumatological disorders in patients visiting a tertiary care centre. METHODS: The retrospective analysis was conducted at the Rheumatology Clinic of Jinnah Postgraduate Medical Centre, Karachi, and comprised prospectively collected data of patients with different musculoskeletal disorders from February 2004 to February 2014. Detailed history, examination and laboratory investigations were recorded in a pre-designed structured proforma...
May 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27179903/cardiovascular-magnetic-resonance-in-rheumatology-current-status-and-recommendations-for-use
#12
REVIEW
Sophie I Mavrogeni, George D Kitas, Theodoros Dimitroulas, Petros P Sfikakis, Philip Seo, Sherine Gabriel, Amit R Patel, Luna Gargani, Stefano Bombardieri, Marco Matucci-Cerinic, Massimo Lombardi, Alessia Pepe, Anthony H Aletras, Genovefa Kolovou, Tomasz Miszalski, Piet van Riel, AnneGrete Semb, Miguel Angel Gonzalez-Gay, Patrick Dessein, George Karpouzas, Valentina Puntmann, Eike Nagel, Konstantinos Bratis, Georgia Karabela, Efthymios Stavropoulos, Gikas Katsifis, Loukia Koutsogeorgopoulou, Albert van Rossum, Frank Rademakers, Gerald Pohost, Joao A C Lima
Targeted therapies in connective tissue diseases (CTDs) have led to improvements of disease-associated outcomes, but life expectancy remains lower compared to general population due to emerging co-morbidities, particularly due to excess cardiovascular risk. Cardiovascular magnetic resonance (CMR) is a noninvasive imaging technique which can provide detailed information about multiple cardiovascular pathologies without using ionizing radiation. CMR is considered the reference standard for quantitative evaluation of left and right ventricular volumes, mass and function, cardiac tissue characterization and assessment of thoracic vessels; it may also be used for the quantitative assessment of myocardial blood flow with high spatial resolution and for the evaluation of the proximal coronary arteries...
August 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27169551/clinical-scenarios-in-chronic-kidney-disease-parenchymal-chronic-renal-diseases-part-2
#13
Ilaria Petrucci, Sara Samoni, Mario Meola
Secondary nephropathies can be associated with disreactive immunological disorders or with a non-inflammatory glomerular damage. In systemic lupus erythematosus (SLE), scleroderma and rheumatoid arthritis as in other connective tissue diseases, kidney volume and cortex echogenicity are the parameters that best correlate with clinical severity of the disease, even if the morphological aspect is generally non-specific. Doppler studies in SLE document the correlation between resistance indexes (RIs) values and renal function...
2016: Contributions to Nephrology
https://www.readbyqxmd.com/read/27149461/cancer-risk-in-patients-with-inflammatory-systemic-autoimmune-rheumatic-diseases-a-nationwide-population-based-dynamic-cohort-study-in-taiwan
#14
Kuang-Hui Yu, Chang-Fu Kuo, Lu Hsiang Huang, Wen-Kuan Huang, Lai-Chu See
The aim of this study was to determine whether inflammation is related to cancer development, and whether the incidence of cancer is increased and occurs in a site-specific manner in patients with systemic autoimmune rheumatic diseases (SARDs).This study included a nationwide dynamic cohort of patients with various newly diagnosed SARDs from 1997 to 2010 with follow-up until 2012.This study included 75,123 patients with SARDs. During 562,870 person-years of follow-up, 2844 patients developed cancer. Between 1997 and 2010, the highest number of newly diagnosed SARDs cases were rheumatoid arthritis (n = 35,182), followed by systemic lupus erythematosus (SLE, n = 15,623), Sjögren syndrome (n = 11,998), Kawasaki disease (n = 3469), inflammatory bowel disease (n = 2853), scleroderma (n = 1814), Behçet disease (n = 1620), dermatomyositis (n = 1119), polymyositis (n = 811), and vasculitis other than Kawasaki disease (n = 644)...
May 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27131766/immunological-and-inflammatory-processes-in-systemic-autoimmune-disease-may-not-only-cause-pericardium-inflammation-but-may-also-cause-mitral-valve-deterioration-and-left-ventricular-wall-thickening
#15
Atsushi Sugiura, Nobusada Funabashi, Koya Ozawa, Yoshio Kobayashi
PURPOSE: Systemic autoimmune disease (SAD) frequently affects the pericardium, and pathology is characterized by both immunological and inflammatory processes. We hypothesized that these processes simultaneously influence mitral-valve (MV) deterioration and left-ventricular (LV) wall thickening in SAD subjects. METHODS: 101 SAD subjects were selected (76 female; 53±17years; systemic-lupus-erythematosus, 26%; vasculitis, 20%; scleroderma, 14%; polymyositis/dermatomyositis complex, 10%; mixed connective tissue disease, 11% and rheumatoid-arthritis, 2%)...
July 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27126733/clinical-characteristics-of-scleroderma-overlap-syndromes-comparisons-with-pure-scleroderma
#16
Chingching Foocharoen, Sittichai Netwijitpan, Ajanee Mahakkanukrauh, Siraphop Suwannaroj, Ratanavadee Nanagara
BACKGROUND: Scleroderma with characteristics of other connective tissue diseases is called scleroderma overlap syndrome (SOV); the clinical features of which have yet to be investigated among Thai patients. OBJECTIVE: To determine the clinical differences between pure scleroderma and SOV. METHODS: A historical cohort study was conducted among patients with pure scleroderma versus those with SOV. Subjects were over 18 years of age and followed up at Srinagarind Hospital, Khon Kaen University, Thailand, between January 2006 and December 2011...
September 2016: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/26912511/management-of-interstitial-lung-disease-associated-with-connective-tissue-disease
#17
REVIEW
Stephen C Mathai, Sonye K Danoff
The lung is a common site of complications of systemic connective tissue disease (CTD), and lung involvement can present in several ways. Interstitial lung disease (ILD) and pulmonary hypertension are the most common lung manifestations in CTD. Although it is generally thought that interstitial lung disease develops later on in CTD it is often the initial presentation ("lung dominant" CTD). ILD can be present in most types of CTD, including rheumatoid arthritis, scleroderma, systemic lupus erythematosus, polymyositis or dermatomyositis, Sjögren's syndrome, and mixed connective tissue disease...
February 24, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/26831786/-screening-for-potential-drug-targets-by-comprehensive-identification-of-disease-specific-antigens-incorporated-into-immune-complexes-in-patients-with-immunological-diseases
#18
Kaname Ohyama
Our immune system resembles an intelligent security system, which continually monitors for foreign invaders (infectious diseases); however, in some cases, this system recognizes healthy parts as something harmful or foreign and then attacks them (autoimmune diseases). The defining characteristics of an autoimmune disease are the existence of T- and B-cell autoreactivity against self proteins (autoantigens). In addition to autoimmune diseases, aberrant host proteins that occur during a certain state of diseases (e...
2016: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/26758437/association-of-serum-kl-6-levels-with-interstitial-lung-disease-in-patients-with-connective-tissue-disease-a-cross-sectional-study
#19
Ekin Oktay Oguz, Orhan Kucuksahin, Murat Turgay, Mustafa Turgut Yildizgoren, Askin Ates, Nalan Demir, Ozlem Ozdemir Kumbasar, Gulay Kinikli, Nursen Duzgun
It was aimed to evaluate KL-6 glycoprotein levels to determine if it may be a diagnostic marker for the connective tissue diseases (CTDs) predicting CTD-related interstitial lung diseases (ILDs) (CTD-ILD) development and to examine if there was a difference between patients and healthy controls. The study included 113 patients with CTD (45 CTD without lung involvement, 68 CTD-ILD) and 45 healthy control subjects. KL-6 glycoprotein levels were analyzed with ELISA in patients and the control group. The relationship between KL-6 glycoprotein levels and CTD-ILD was assessed...
March 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/26742238/-interstitial-lung-disease-in-connective-tissue-diseases
#20
B Duxbury, T Rochat
Interstitial lung disease represents a major clinical aspect of the four major connective tissue diseases: rheumatoid arthritis, scleroderma, polymyositis/dermatomyositis and systemic lupus erythematosus (SLE). Early recognition in the course of the disease is essential, as interstitial lung disease will often determine the vital prognosis of these patients. Treatment is most frequently based on experts' opinion, because there are only few randomized controlled trials in this field.
November 18, 2015: Revue Médicale Suisse
keyword
keyword
101049
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"