Yubing Li, Xinyu Deng, Qichao Hu, Yuan Chen, Wenwen Zhang, Xuhua Qin, Feng Wei, Xiaohua Lu, Xiao Ma, Jinhao Zeng, Thomas Efferth
ETHNOPHARMACOLOGICAL RELEVANCE: Paeonia lactiflora Pall. (PLP), a traditional Chinese medicine, is recognized for its antioxidative and anti-apoptotic properties. Despite its potential medicinal value, the mechanisms underlying its efficacy have been less explored, particularly in alleviating acute liver injury (ALI) caused by excessive intake of acetaminophen (APAP). AIM OF THE STUDY: This study aims to elucidate the role and mechanisms of PLP in mitigating oxidative stress and apoptosis induced by APAP...
April 8, 2024: Journal of Ethnopharmacology