Read by QxMD icon Read

ophidic accident

Fernanda Gobbi Amorim, Romualdo Morandi-Filho, Patricia Tieme Fujimura, Carlos Ueira-Vieira, Suely Vilela Sampaio
Snakebites are a serious health problem in tropical countries. In Brazil, the genus Bothrops (Viperidae family) causes most of the ophidic accidents, characterized by proteolysis and haemorrhage. Snake venoms are rich sources of toxins with great therapeutic and biotechnological potential and omics approaches is a valuable tool for identification of new bioactive components in the venom. In this study, we described the first transcriptome of the venom gland of Bothrops moojeni snake, using the next-generation sequencing with the Illumina platform...
October 28, 2017: Toxicon: Official Journal of the International Society on Toxinology
David Meléndez-Martínez, Eduardo Macías-Rodríguez, Rodrigo Vázquez-Briones, Estuardo López-Vera, Martha Sandra Cruz-Pérez, Alejandra Vargas-Caraveo, Ana Gatica-Colima, Luis Fernando Plenge-Tellechea
The Mexican black-tailed rattlesnake Crotalus molossus nigrescens is distributed in the Mexican plateau. Its venom is known to cause hemolysis and presents fibrinogen coagulase, collagenase and fibrinolytic activities. These activities may be associated with hemostatic alterations, such as platelet aggregation, hemolysis and fibrinolysis, often described in ophidic accidents. However, the mechanisms of action of the C. m. nigrescens venom remain unclear. In this study we investigated the in vitro hemotoxic, neurotoxic, and vasculotoxic effects of the venom...
2017: Journal of Venom Research
Patrícia T Baraldi, Angelo J Magro, Fábio F Matioli, Silvana Marcussi, Ney Lemke, Leonardo A Calderon, Rodrigo G Stábeli, Andreimar M Soares, Arlene G Correa, Marcos R M Fontes
Metalloproteases play a fundamental role in snake venom envenomation inducing hemorrhagic, fibrigen(ogen)olytic and myotoxic effects in their victims. Several snake venoms, such as those from the Bothrops genus, present important local effects which are not efficiently neutralized by conventional serum therapy. Consequently, these accidents may result in permanent sequelae and disability, creating economic and social problems, especially in developing countries, leading the attention of the World Health Organization that considered ophidic envenomations a neglected tropical disease...
February 2016: Biochimie
Fabrício F A Fernandes, Marcelo A Tomaz, Camila Z El-Kik, Marcos Monteiro-Machado, Marcelo A Strauch, Bruno L Cons, Matheus S Tavares-Henriques, Adélia C O Cintra, Valdir A Facundo, Paulo A Melo
ETHNOPHARMACOLOGICAL RELEVANCE: Serotherapy against snakebite is often unavailable in some regions over Brazil, where people make use of plants from folk medicine to deal with ophidic accidents. About 10% of Combretum species have some ethnopharmacological use, including treatment of snakebites. MATERIALS AND METHODS: We evaluated the ability of the extract of Combretum leprosum and its component arjunolic acid to reduce some in vivo and in vitro effects of Bothrops jararacussu and Bothrops jararaca venoms...
August 8, 2014: Journal of Ethnopharmacology
Polianna L M M Albuquerque, Camilla N Jacinto, Geraldo B Silva Junior, Juliana B Lima, Maria do Socorro B Veras, Elizabeth F Daher
Ophidic accidents are an important public health problem due to their incidence, morbidity and mortality. An increasing number of cases have been registered in Brazil in the last few years. Several studies point to the importance of knowing the clinical complications and adequate approach in these accidents. However, knowledge about the risk factors is not enough and there are an increasing number of deaths due to these accidents in Brazil. In this context, acute kidney injury (AKI) appears as one of the main causes of death and consequences for these victims, which are mainly young males working in rural areas...
September 2013: Revista do Instituto de Medicina Tropical de São Paulo
Leonardo De Sousa, Jessica Bastouri-Carrasco, Mercedes Matos, Adolfo Borges, Stefano Bónoli, Aleikar Vásquez-Suárez, Belsy Guerrero, Alexis Rodríguez-Acosta
The data of accidents caused by snakebites in Venezuela, registered at the morbidity statistics of the Direction of Epidemiology and Strategic Analysis of the Ministry of Health and Social Development were analyzed. During the years of 1996-2004, 53,792 snakebites were registered in Venezuela (5,976 cases average per year), with a higher incidence during the year 2004 (7,486 incidents). Zulia reported the highest frequency of all the states (5,975 cases); meanwhile the Midwestern region, constituted by Lara, Portuguesa, Falc6n and Yaracuy states, had a higher morbidity for snake bites...
June 2013: Investigación Clínica
Fagner Neves Oliveira, Monalisa Taveira Brito, Isabel Cristina Oliveira de Morais, Sayonara Maria Lia Fook, Helder Neves de Albuquerque
INTRODUCTION: Bothrops and Bothropoides snakes cause 70% of the ophidic accidents in Brazil. The species that cause ophidic accidents in State of Paraíba are Bothropoides erythromelas, Bothrops leucurus and Bothropoides neuwiedi. METHODS: This is a prospective and transverse study, following a quantitative approach of accidents involving Bothrops and Bothropoides admitted to the Toxicological Assistance and Information Centers of Campina Grande and João Pessoa (Ceatox-CG and Ceatox-JP), aimed at identifying the epidemiological and clinical profile of such accidents...
November 2010: Revista da Sociedade Brasileira de Medicina Tropical
Elda E Sánchez, Alexis Rodríguez-Acosta
Natural inhibitors of snake venoms play a significant role in the ability to neutralize the degradation effects induced by venom toxins. It has been known for many years that animal sera and some plant extracts are competent in neutralizing snake venoms. The purpose of this review is to highlight the recent work that has been accomplished with natural inhibitors of snake venoms as well as revisiting the past research including those found in plants. The biomedical value of these natural inhibitors can lead to the development of new therapeutics for an assortment of diseases as well as contributing to efficient antivenoms for the treatment of ophidic accidents...
2008: Immunopharmacology and Immunotoxicology
Leonardo De Sousa, Dioniris Vásquez, Doyra Salazar, Rigoberto Valecillos, Dionisio Vásquez, María Rojas, Pedro Parrila-Alvarez, Mercedes Quiroga
Human mortality due to envenomation by animals in Monagas state, Venezuela was evaluated. In this state 47 deaths due to envenomations produced by vertebrates and invertebrates (scorpions = 21, snakes = 20, bees = 6) during the period 1980-2000 were registered. The mountainous area, at the north of the state (Turimiquire sub-region) and its piedmonts reported most of the mortality by scorpionism (57.2%) and ophidism (70.0%). The age group of the patients was related with the sort of envenomation causing the death...
September 2005: Investigación Clínica
Viviana Lión, Adriana Rojas, Alexis Rodríguez-Acosta
This latex agglutination test was designed as a tool in the diagnosis of the ophidic accidents The development of specific trials to identify venoms from the most common snakes inVenezuela in human sera, could contribute to the improvement of the diagnosis of these accidents caused by snakes of the Bothrops and Crotalus genera, and in the control of the antiophidic serum for the treatment in an adequate and immediate way. The results obtained revealed a sensitivity of 167 mg/mL with good specificity, rapidity (10 minutes) and simplicity, since it can be accomplished by personnel with a basic training and only a microscope is necessary...
January 2004: Revista Cubana de Medicina Tropical
Fábia Maria Oliveira Pinho, Elane Silva Oliveira, Fernanda Faleiros
UNLABELLED: Ophidic accidents are a serious health problem for tropical countries, because are responsible for the high incidence of morbidity and mortality. PURPOSE: This article describes aspects of snakebite epidemiology in the State of Goiás, Brazil. METHODS: Notifications about the accidents caused by poisonous snakes have been analysed for Government of the State of Goiás (Brazil), Health Department, from 1998 to 2000. RESULTS: In this period, 3261 accidents caused by poisonous snakes have been notified, which represented the average annual incidence rate of 20 to 23/100,000 persons...
January 2004: Revista da Associação Médica Brasileira
B J Hawgood
Dr Vital Brazil was a great humanitarian and pioneer of medical science. His main work arose from his concern with poisonous snakebite accidents to labourers working the land. Vital Brazil estimated that, at the beginning of this century, deaths due to crotaline snakebites in the State of São Paulo, Brazil, were nearly 3000 per year, representing a mortality rate of about 25%, the majority being due to bothropic envenomation. After reading a report of Calmette's anti-Naja serum, Vital Brazil raised monovalent serum against the venom of Bothrops jararaca and the venom of Crotalus durissus terrificus...
May 1992: Toxicon: Official Journal of the International Society on Toxinology
L Rosado-López, A Laviada-Arrigunaga
Thirty-eight patients admitted into the Hospital Escuela O'Horán for snake bites were studied. Most of them, 68.4 per cent, were from the state of Yucatan; 18.4 per cent from the state of Cameche and 13.1 per cent from the state of Quintana Roo. There was a predominance for the males (86.8 per cent); the most frequent age was the third decade (20-30 years) and most of these patients were peasants and students. The species identified in most of the accidents (63 per cent) were C. terrificus and B. atrox in equal proportions, and the body sections more often affected were the distal portions of the members...
September 1977: La Prensa Médica Mexicana
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"