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JOURNAL ARTICLE
Fizza Mushtaq, Madeeha Ashfaq, Fareeha Anwar, Badarqa Tul Ayesha, Hafiz Shahid Latif, Sadia Khalil, Hafiz Shoaib Sarwar, Muhammad Imran Khan, Muhammad Farhan Sohail, Iram Maqsood
Wound healing, particularly for difficult-to-treat wounds, presents a serious threat and may lead to complications. Currently available dressings lack mucoadhesion, safety, efficacy, and, most importantly, patient compliance. Herein, we developed a unique, simple, and inexpensive injectable chitosan-methoxy polyethylene glycol (chitosan-mPEG) hybrid hydrogel with tunable physicochemical and mechanical properties for wound healing. The detailed physicochemical and rheological characterization of the chitosan-mPEG hydrogel has revealed chemical interaction between available -NH2 groups of chitosan and -COOH groups of mPEG acid, which, to our perspective, enhanced the mechanical and wound healing properties of hybrid chitosan and mPEG hydrogel compared to solo chitosan or PEG hydrogel...
January 16, 2024: ACS Omega
#2
REVIEW
Anees Ur Rehman, Mahnoor Khattak, Usman Mushtaq, Muhammad Latif, Imran Ahmad, Muhammad Fawad Rasool, Sadia Shakeel, Khezar Hayat, Rabia Hussain, Ghaidaa Ali Alhazmi, Afnan Owedah Alshomrani, Mohammed Ibrahim Alalawi, Saleh Alghamdi, Mohammad Tarique Imam, Safa S Almarzoky Abuhussain, Sarah M Khayyat, Abdul Haseeb
BACKGROUND: The existence of Type 2 Diabetes Mellitus (DM) in tuberculosis (TB) patients is very dangerous for the health of patients. One of the major concerns is the emergence of MDR-TB in such patients. It is suspected that the development of MDR-TB further worsens the treatment outcomes of TB such as treatment failure and thus, causes disease progression. AIM: To investigate the impact of DM on the Emergence of MDR-TB and Treatment Failure in TB-DM comorbid patients...
2023: Frontiers in Public Health
#3
JOURNAL ARTICLE
Peter W Harrison, M Ridwan Amode, Olanrewaju Austine-Orimoloye, Andrey G Azov, Matthieu Barba, If Barnes, Arne Becker, Ruth Bennett, Andrew Berry, Jyothish Bhai, Simarpreet Kaur Bhurji, Sanjay Boddu, Paulo R Branco Lins, Lucy Brooks, Shashank Budhanuru Ramaraju, Lahcen I Campbell, Manuel Carbajo Martinez, Mehrnaz Charkhchi, Kapeel Chougule, Alexander Cockburn, Claire Davidson, Nishadi H De Silva, Kamalkumar Dodiya, Sarah Donaldson, Bilal El Houdaigui, Tamara El Naboulsi, Reham Fatima, Carlos Garcia Giron, Thiago Genez, Dionysios Grigoriadis, Gurpreet S Ghattaoraya, Jose Gonzalez Martinez, Tatiana A Gurbich, Matthew Hardy, Zoe Hollis, Thibaut Hourlier, Toby Hunt, Mike Kay, Vinay Kaykala, Tuan Le, Diana Lemos, Disha Lodha, Diego Marques-Coelho, Gareth Maslen, Gabriela Alejandra Merino, Louisse Paola Mirabueno, Aleena Mushtaq, Syed Nakib Hossain, Denye N Ogeh, Manoj Pandian Sakthivel, Anne Parker, Malcolm Perry, Ivana Piližota, Daniel Poppleton, Irina Prosovetskaia, Shriya Raj, José G Pérez-Silva, Ahamed Imran Abdul Salam, Shradha Saraf, Nuno Saraiva-Agostinho, Dan Sheppard, Swati Sinha, Botond Sipos, Vasily Sitnik, William Stark, Emily Steed, Marie-Marthe Suner, Likhitha Surapaneni, Kyösti Sutinen, Francesca Floriana Tricomi, David Urbina-Gómez, Andres Veidenberg, Thomas A Walsh, Doreen Ware, Elizabeth Wass, Natalie L Willhoft, Jamie Allen, Jorge Alvarez-Jarreta, Marc Chakiachvili, Bethany Flint, Stefano Giorgetti, Leanne Haggerty, Garth R Ilsley, Jon Keatley, Jane E Loveland, Benjamin Moore, Jonathan M Mudge, Guy Naamati, John Tate, Stephen J Trevanion, Andrea Winterbottom, Adam Frankish, Sarah E Hunt, Fiona Cunningham, Sarah Dyer, Robert D Finn, Fergal J Martin, Andrew D Yates
Ensembl (https://www.ensembl.org) is a freely available genomic resource that has produced high-quality annotations, tools, and services for vertebrates and model organisms for more than two decades. In recent years, there has been a dramatic shift in the genomic landscape, with a large increase in the number and phylogenetic breadth of high-quality reference genomes, alongside major advances in the pan-genome representations of higher species. In order to support these efforts and accelerate downstream research, Ensembl continues to focus on scaling for the rapid annotation of new genome assemblies, developing new methods for comparative analysis, and expanding the depth and quality of our genome annotations...
November 11, 2023: Nucleic Acids Research
#4
Luna Bajracharya, Meena Lall, Sunita Bijarnia-Mahay, Praveen Kumar, Imran Mushtaq, Pushpa Saviour, Preeti Paliwal, Anju Joshi, Shruti Agarwal, Praveen Suman
INTRODUCTION: There is evidence that neurodevelopmental disorders are associated with chromosomal abnormalities. Current genetic testing can clinch an exact diagnosis in 20-25% of such cases. Case Description. A 3 years and 11 months old boy with global developmental delay had repetitive behaviors and hyperkinetic movements. He was stunted and underweight. He had ataxia, limb dyskinesia, triangular face, microcephaly, upward slanting palpebral fissure, hypertelorism, retrognathia, posteriorly rotated ears, long philtrum, thin lips, broad nasal tip, polydactyly, tappering fingers, and decreased tone in the upper and lower limbs with normal deep tendon reflexes...
2023: Case Reports in Genetics
#5
REVIEW
Komal Imran, Muhammad Javed Iqbal, Rameesha Abid, Muhammad Mushtaq Ahmad, Daniela Calina, Javad Sharifi-Rad, William C Cho
MicroRNAs (miRNAs) are small non-coding RNA molecules that play pivotal roles in regulating gene expression and have been implicated in the pathogenesis of numerous cancers. miRNA-3652, though relatively less explored, has recently emerged as a potential key player in ovarian cancer's molecular landscape. This review aims to delineate the functional significance and tumor progression role of miRNA-3652 in ovarian cancer, shedding light on its potential as both a diagnostic biomarker and therapeutic target. A comprehensive literature search was carried out using established databases, the focus was on articles that reported the role of miRNA-3652 in ovarian cancer, encompassing mechanistic insights, functional studies, and its association with clinical outcomes...
October 16, 2023: Cell Communication and Signaling: CCS
#6
JOURNAL ARTICLE
Naeem Rasool, Muhammad Ovais Omer, Aqeel Javeed, Muhammad Nawaz, Muhammad Imran, Muzzamal Hussain, Zarina Mushtaq, Entessar Al Jbawi
Argyrolobium roseum (Camb.) Jaub & Spach ( Papilionaceae ) is a medicinal plant, cultivated in northern areas of Pakistan. The consumption of trace minerals (lead) is very toxic to the vital organs of the body, therefore the overcome of these minerals is very necessary. In this regard, this study aimed to assess the potential pharmacological effect of aqueous and ethanolic extract of Argyrolobium roseum (Camb.) Jaub & Spach against pb-induced oxidative stress, histological changes in Pb-induced rats' liver and kidney, and anti-inflammatory effect...
October 2023: Food Science & Nutrition
#7
JOURNAL ARTICLE
Abdullah, Shabir Hussain, Weizhen Ji, Hammal Khan, Emily K Mis, Rabiha Mushtaq, Mirub Chodhary, Muhammad Hassan Raza, Abid Jan, Imran Ullah, Mustafa K Khokha, Saquib A Lakhani, Wasim Ahmad
No abstract text is available yet for this article.
September 30, 2023: Clinical Genetics
#8
JOURNAL ARTICLE
Jai K Das, Amira Khan, Farhana Tabassum, Zahra Ali Padhani, Atif Habib, Mushtaq Mirani, Abdu R Rahman, Zahid Ali Khan, Arjumand Rizvi, Imran Ahmed, Zulfiqar Bhutta
Poliomyelitis is a condition of great concern and is endemic in only two countries of the world: Pakistan and Afghanistan. Community mobilization plays a vital role in raising awareness and can help reduce polio vaccine refusals. The objective of this study will be to decrease polio vaccine refusals and zero-dose vaccines by motivating behavior change through the provision of conditional-collective-community-based incentives (C3Is) based on a reduction in polio vaccine refusals. The project will adopt a pretest/post-test quasi-experimental design with two intervention high-risk union councils (HRUCs) and two control union councils (UCs) of peri-urban (Karachi) and rural (Bannu) settings in Pakistan...
September 8, 2023: Methods and Protocols
#9
JOURNAL ARTICLE
Urooj Akram, Wareesa Sharif, Mobeen Shahroz, Muhammad Faheem Mushtaq, Daniel Gavilanes Aray, Ernesto Bautista Thompson, Isabel de la Torre Diez, Sirojiddin Djuraev, Imran Ashraf
An Internet of Things (IoT) network is prone to many ways of threatening individuals. IoT sensors are lightweight, lack complicated security protocols, and face threats to privacy and confidentiality. Hackers can attack the IoT network and access personal information and confidential data for blackmailing, and negatively manipulate data. This study aims to propose an IoT threat protection system (IoTTPS) to protect the IoT network from threats using an ensemble model RKSVM, comprising a random forest (RF), K nearest neighbor (KNN), and support vector machine (SVM) model...
July 13, 2023: Sensors
#10
JOURNAL ARTICLE
Afifa Tanweer, Mutayyabah Zia, Kainat Riaz, Hina Mushtaq, Momel Siddique, Samra Imran, Ayesha Humayun, Zaib-Un-Nisa Hussain
BACKGROUND: The flaws in dietary assessment methods can generate misleading information and thus may impact on the interventions planned based on that information. Context specific digitalization of dietary assessment tools is a potential way forward to reduce biases and resources involved in data handling. METHODS: Two versions of Twenty-Four Hour Recall (24HR) (traditional [24HR Ver-01] and digital [24HR Ver-02]) were tested for data agreement and feasibility by gathering cross sectional paired data on both the versions from 102 participants (18-25 years age)...
June 28, 2023: Computer Methods and Programs in Biomedicine
#11
REVIEW
Qandeel Rafique, Ali Rehman, Muhammad Sher Afghan, Hafiz Muhamad Ahmad, Imran Zafar, Kompal Fayyaz, Quratul Ain, Rehab A Rayan, Khadija Mohammed Al-Aidarous, Summya Rashid, Gohar Mushtaq, Rohit Sharma
The COVID-19 pandemic has necessitated the development of reliable diagnostic methods for accurately detecting the novel coronavirus and its variants. Deep learning (DL) techniques have shown promising potential as screening tools for COVID-19 detection. In this study, we explore the realistic development of DL-driven COVID-19 detection methods and focus on the fully automatic framework using available resources, which can effectively investigate various coronavirus variants through modalities. We conducted an exploration and comparison of several diagnostic techniques that are widely used and globally validated for the detection of COVID-19...
June 20, 2023: Computers in Biology and Medicine
#12
Muhammad Imran Khan, Abdallah Shanableh, Noureddine Elboughdiri, Mushtaq Hussain Lashari, Suryyia Manzoor, Shabnam Shahida, Nosheen Farooq, Yassine Bouazzi, Sarra Rejeb, Zied Elleuch, Karim Kriaa, Aziz Ur Rehman
[This corrects the article DOI: 10.1021/acsomega.2c03148.].
April 18, 2023: ACS Omega
#13
JOURNAL ARTICLE
Francisco Reed, Ximena Recabal, Pilar Echeverría, Luis H Braga, Abraham Cherian, John M Gatti, Luis Garcia-Aparicio, Sonia Perez-Bertolez, Francisco de Badiola, Anna Bujons, Juan Manuel Moldes, Imran Mushtaq, Pedro-José López
INTRODUCTION: Anderson-Hynes pyeloplasty is the technique of choice for the treatment of pyeloureteral junction obstruction (PUJO) with an excellent success rate. Minimally invasive surgery has become the standard of care for the management of PUJO in children. Although it has been comparable to the open approach at all levels, its diffusion or employment in younger children has not been widely adopted. Our aim is to evaluate laparoscopic pyeloplasty outcomes from international academic centers in children under 1 year of age, focusing on feasibility and outcomes including possible complications...
March 22, 2023: World Journal of Urology
#14
JOURNAL ARTICLE
Muhammad Imran Khan, Abdallah Shanableh, Akram M Alfantazi, Mushtaq Hussain Lashari, Suryyia Manzoor, Ramsha Anwer, Nosheen Farooq, Farid A Harraz, Mabkhoot Alsaiari, M Faisal
Commercially available QPPO/PVA based anion exchange membrane (AEM) BIII was to inquire the percentage discharge of anionic dye Eosin-B (EB) at terrain temperature from wastewater. The impact of EB initial concentration, membrane dosage, ionic strength, contact time and temperature on EB percentage removal was contemplated. The EB percentage removal was increased from 22 to 99.56% and 38.15-99.56% with contact time and membrane dosage respectively while decreased from 99.56 to 29%, 99.56 to 54.61% and 99.56 to 92...
January 30, 2023: Chemosphere
#15
JOURNAL ARTICLE
Riwa Meshaka, Lorenzo Biassoni, Gorsey Leung, Imran Mushtaq, Melanie P Hiorns
Pelviureteric junction obstruction, also known as ureteropelvic junction obstruction, is a congenital narrowing of the urinary excretory tract at the junction between the renal pelvis and the ureter and is a common cause of congenital pelvicalyceal dilatation. The outcome is variable, from spontaneous resolution to renal parenchymal function loss in cases of untreated high-grade obstruction. Abnormalities in renal ascent, rotation and vascularity can be associated with pelviureteric junction obstruction and easily overlooked radiologically...
December 20, 2022: Pediatric Radiology
#16
JOURNAL ARTICLE
Muhammad Mushtaq Ahmad, Tahir Mahmood Qureshi, Maham Mushtaq, Amjad Islam Aqib, Umair Mushtaq, Salam A Ibrahim, Abdul Rehman, Muhammad Waheed Iqbal, Tabish Imran, Shahida Anusha Siddiqui, Anjum Javed, Sadaf Shamim, Muhammad Hamzah Saleem
The core objective of the present study was to evaluate the influence of baking/frying times and temperatures on the formation of acrylamide in bakery, snack, and fried products such as biscuits, muffins, pizza, cakes, samosa, paratha rolls, nuggets, and potato cutlets during baking/frying at different times and temperature conditions. First of all, the raw material, especially flour, was tested for its proximate composition and rheological characteristics. The quantification of acrylamide produced during the processing of different products was carried out through the HPLC method...
2022: Frontiers in Nutrition
#17
JOURNAL ARTICLE
Sajid Raza Zaidi, Najam Ul Qadir, Syed Husain Imran Jaffery, Muhammad Ali Khan, Mushtaq Khan, Jana Petru
Due to the increasing demand for higher production rates in the manufacturing sector, there is a need to manufacture finished or near-finished parts. Burrs and surface roughness are the two most important indicators of the surface quality of any machined parts. In addition to this, there is a constant need to reduce energy consumption during the machining operation in order to reduce the carbon footprint. Milling is one of the most extensively used cutting processes in the manufacturing industry. This research was conducted to investigate the effect of machining parameters on surface roughness, burr width, and specific energy consumption...
November 15, 2022: Materials
#18
JOURNAL ARTICLE
Elim Man, Imran Mushtaq, Angela Barnicoat, Polly Carmichael, Claire R Hughes, Kate Davies, Helen Aitkenhead, Rakesh Amin, Charles R Buchanan, Abraham Cherian, Nikola J Costa, Sarah M Creighton, Patrick G Duffy, Emma Hewson, Peter C Hindmarsh, Louisa C Monzani, Catherine J Peters, Philip G Ransley, Naima Smeulders, Helen A Spoudeas, Dan Wood, Ieuan A Hughes, Harshini Katugampola, Caroline E Brain, Mehul T Dattani, John C Achermann
CONTEXT: Differences of sex development (DSD) represent a wide range of conditions presenting at different ages to various health professionals. Establishing a diagnosis, supporting the family, and developing a management plan are important. OBJECTIVE: We aimed to better understand the presentation and prevalence of pediatric DSD. METHODS: A retrospective, observational cohort study was undertaken in a single tertiary pediatric center of all children and young people (CYP) referred to a DSD multidisciplinary team over 25 years (1995-2019)...
November 17, 2022: Journal of the Endocrine Society
#19
JOURNAL ARTICLE
Sardar Ahmed, Mushtaq Ahmad, Muhammad Hasnain Yousaf, Sumain Haider, Zahid Imran, S S Batool, Ishaq Ahmad, Muhammad Imran Shahzad, Muhammad Azeem
Nickel-cobalt sulfide (NiCo2 S4 ) is a prominent member of bimetallic transition metal sulfides. It is being widely used for a variety of applications such as electrode material, photocatalysis, and energy storage devices (like pseudo capacitors, supercapacitors, solar cells, and fuel cells) due to its better electronic conductivity, manageable morphology, and high capacitance. This work presents the one-step solventless synthesis of NiCo2 S4 sheet-like nanostructures and then explores their metallic nature...
2022: Frontiers in Chemistry
#20
JOURNAL ARTICLE
Pilar Echeverria, Francisco Reed L, John M Gatti, Luis H Braga, Abraham Cherian, Luis Garcia-Aparicio, Peter Metcalfe, Javier Ruiz, Juan I Bortagaray, Oriol Martin-Sole, Marc David Leclair, Anna Bujons, Francisco de Badiola, Robert Coleman, Nathalie R Webb, Juan Pablo Corbetta, Juan Manuel Moldes, Imran Mushtaq, Pedro-Jose Lopez
PURPOSE: The Anderson-Hynes technique has been the treatment of choice for primary ureteropelvic junction obstruction in children. Laparoscopic approach has shown similar outcomes to open, with advantages of shorter hospital stay and less pain. We reviewed the experience of 11 geographically diverse, tertiary pediatric urology institutions focusing on the outcomes and complications of laparoscopic pyeloplasty. MATERIALS AND METHODS: A descriptive, retrospective study was conducted evaluating patients undergoing Anderson-Hynes dismembered laparoscopic pyeloplasty...
October 8, 2022: Journal of Pediatric Urology
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