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Nonadherence

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https://www.readbyqxmd.com/read/28104578/a-web-disseminated-self-help-and-peer-support-program-could-fill-gaps-in-mental-health-care-lessons-from-a-consumer-survey
#1
Samantha L Bernecker, Kaitlin Banschback, Gennarina D Santorelli, Michael J Constantino
BACKGROUND: Self-guided mental health interventions that are disseminated via the Web have the potential to circumvent barriers to treatment and improve public mental health. However, self-guided interventions often fail to attract consumers and suffer from user nonadherence. Uptake of novel interventions could be improved by consulting consumers from the beginning of the development process in order to assess their interest and their preferences. Interventions can then be tailored using this feedback to optimize appeal...
January 19, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28103810/prioritizing-problems-in-and-solutions-to-homecare-safety-of-people-with-dementia-supporting-carers-streamlining-care
#2
Lorainne Tudor Car, Mona El-Khatib, Robert Perneczky, Nikolaos Papachristou, Rifat Atun, Igor Rudan, Josip Car, Charles Vincent, Azeem Majeed
BACKGROUND: Dementia care is predominantly provided by carers in home settings. We aimed to identify the priorities for homecare safety of people with dementia according to dementia health and social care professionals using a novel priority-setting method. METHODS: The project steering group determined the scope, the context and the criteria for prioritization. We then invited 185 North-West London clinicians via an open-ended questionnaire to identify three main problems and solutions relating to homecare safety of people with dementia...
January 19, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28101321/switching-away-from-pipotiazine-palmitate-a-naturalistic-study
#3
Feras Ali Mustafa
BACKGROUND: In March 2015, pipotiazine palmitate depot antipsychotic was globally withdrawn due to the shortage of its active ingredient. Thus, all patients receiving this medication had to be switched to an alternative antipsychotic drug. In this study we set to evaluate the process of switching away from pipotiazine palmitate within our clinical service, and its impact on hospitalization. METHODS: Demographic and clinical data on patients who were receiving pipotiazine palmitate in Northamptonshire at the time of its withdrawal were anonymously extracted from their electronic records and analyzed using descriptive statistics...
January 2017: Therapeutic Advances in Psychopharmacology
https://www.readbyqxmd.com/read/28097300/precision-benefit-design-using-smarter-deductibles-to-better-engage-consumers-and-mitigate-cost-related-nonadherence
#4
A Mark Fendrick, Michael E Chernew
No abstract text is available yet for this article.
January 9, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28095965/vamonos-veterans-affairs-metabolism-obstructed-and-non-obstructed-sleep-study-effects-of-cpap-therapy-on-glucose-metabolism-in-patients-with-obstructive-sleep-apnea
#5
Octavian C Ioachimescu, Jeremy Anthony, Tina Constantin, Mary-Margaret Ciavatta, Kandace McCarver, Mary Ellen Sweeney
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) and type 2 diabetes mellitus (T2DM) are prevalent disorders that pose increased risk of cardiovascular disease and death. The objective of this study was to clarify if continuous positive airway pressure (CPAP) therapy for OSA affects T2DM control and emergence. METHODS: Point-of-care, comparative effectiveness study; cross-sectional and longitudinal analyses. RESULTS: Our cohort included 928 consecutive patients; 13% were women; 36% were Caucasians and 61% African-Americans...
January 11, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28090289/an-international-physician-survey-of-chronic-thromboembolic-pulmonary-hypertension-management
#6
Henning Gall, Ioana R Preston, Barbara Hinzmann, Sabina Heinz, David Jenkins, Nick H Kim, Irene Lang
We conducted an international study to evaluate practices in the diagnosis and management of patients with chronic thromboembolic pulmonary hypertension (CTEPH) globally across different regions. Between August and October 2012, CTEPH-treating physicians completed a 15-minute online questionnaire and provided patient record data for their 2-5 most recent patients with CTEPH. Overall, 496 physicians (Europe: 260; United States: 152; Argentina: 52; Japan: 32) completed the questionnaire and provided patient record data for 1,748 patients...
December 2016: Pulmonary Circulation
https://www.readbyqxmd.com/read/28087496/digital-pills-to-measure-opioid-ingestion-patterns-in-emergency-department-patients-with-acute-fracture-pain-a-pilot-study
#7
Peter R Chai, Stephanie Carreiro, Brendan J Innes, Rochelle K Rosen, Conall O'Cleirigh, Kenneth H Mayer, Edward W Boyer
BACKGROUND: Nonadherence to prescribed regimens for opioid analgesic agents contributes to increasing opioid abuse and overdose death. Opioids are frequently prescribed on an as-needed basis, placing the responsibility to determine opioid dose and frequency with the patient. There is wide variability in physician prescribing patterns because of the lack of data describing how patients actually use as-needed opioid analgesics. Digital pill systems have a radiofrequency emitter that directly measures medication ingestion events, and they provide an opportunity to discover the dose, timing, and duration of opioid therapy...
January 13, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28087390/family-building-after-breast-cancer-considering-the-effect-on-adherence-to-adjuvant-endocrine-therapy
#8
Catherine Benedict, Bridgette Thom, Eleonora Teplinsky, Jane Carleton, Joanne F Kelvin
Adherence to endocrine therapy (ET) is a longstanding problem in breast cancer (BC) survivorship care, particularly among younger women. Younger patients have reported lower ET initiation rates and greater rates of early discontinuation and are considered an "at risk" group for nonadherence. For women who hope to have children in the future, concerns about premature menopause and the implications of postponing childbearing for the 5 to 10 years of ET are widespread. Preliminary evidence suggests that prioritizing fertility, along with concerns about side effects, leads to ET noninitiation and early discontinuation...
December 24, 2016: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28079536/non-vitamin-k-antagonist-oral-anticoagulants-in-patients-with-severe-inherited-thrombophilia-a-series-of-33-patients
#9
Anetta Undas, Tadeusz Goralczyk
The aim of the study was to investigate whether treatment with non-vitamin K antagonist oral anticoagulants (NOACs) is effective and well tolerated in real-life patients following venous thromboembolism (VTE) associated with severe inherited thrombophilia. We evaluated 33 consecutive patients with severe inherited thrombophilia, defined as the presence of deficiencies in protein C, protein S, or anti-thrombin, homozygous factor V Leiden and prothrombin G20210A mutations, or combined defects. The patients were recruited from March 2010 to December 2015 and followed till July 2016...
January 12, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28068170/factors-associated-with-early-discontinuation-of-study-treatment-in-the-mammary-prevention-3-breast-cancer-chemoprevention-trial
#10
Olivia Meggetto, Elizabeth Maunsell, Rowan Chlebowski, Paul Goss, Dongsheng Tu, Harriet Richardson
Purpose Aromatase inhibitors are established breast cancer chemoprevention interventions. However, nonadherence remains a significant challenge. We investigated the association between worsening menopause-specific quality of life, baseline participant characteristics, and early treatment discontinuation within the Mammary Prevention.3 (MAP.3) breast cancer prevention trial. Methods In the MAP.3 randomized, placebo-controlled trial evaluating exemestane, participants completed the Menopause-Specific Quality of Life Questionnaire (MENQOL) at entry and at 6 months...
January 9, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28065393/quality-indicators-in-the-management-of-bladder-cancer-a-modified-delphi-study
#11
Satya R Khare, Armen Aprikian, Peter Black, Normand Blais, Chris Booth, Fadi Brimo, Joseph Chin, Peter Chung, Darrel Drachenberg, Libni Eapen, Adrian Fairey, Neil Fleshner, Yves Fradet, Geoffrey Gotto, Jonathan Izawa, Michael Jewett, Girish Kulkarni, Louis Lacombe, Ron Moore, Chris Morash, Scott North, Ricardo Rendon, Fred Saad, Bobby Shayegan, Robert Siemens, Alan So, Srikala S Sridhar, Samer L Traboulsi, Wassim Kassouf
BACKGROUND: Survival in patients with bladder cancer has only moderately improved over the past 2 decades. A potential reason for this is nonadherence to clinical guidelines and best practice, leading to wide variations in care. Common quality indicators (QIs) are needed to quantify adherence to best practice and provide data for benchmarking and quality improvement. OBJECTIVE: To produce an evidence- and consensus-based list of QIs for the management of bladder cancer...
January 3, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28060084/can-we-identify-minority-patients-at-risk-of-nonadherence-to-antiplatelet-medication-at-the-time-of-coronary-stent-placement
#12
Ana M Palacio, Denise C Vidot, Leonardo J Tamariz, Claudia Uribe, Leslie Hazel-Fernandez, Hua Li, Sylvia D Garay, Olveen Carrasquillo
BACKGROUND: Lack of medication adherence is associated with significant morbidity and mortality, particularly among minorities. We aim to identify predictors of nonadherence to antiplatelet medications at the time of percutaneous coronary intervention (PCI) with stent among African American and Hispanic patients. METHODS: We used data collected for a randomized clinical trial that recruited 452 minority patients from a large US health insurance organization in 2010 post-PCI to compare telephone-based motivational interviewing by trained nurses with an educational video...
January 5, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28049549/long-term-evaluation-of-the-get-fit-for-active-living-program
#13
Liza Stathokostas, Mark Speechley, Robert M D Little, Shawna Doerksen, Jennifer Copeland, Donald H Paterson
This study examined six- and 12-month levels of adherence to physical activity, functional changes, and psychosocial determinants of physical activity in 176 older adults who participated in the "Get Fit for Active Living (GFAL)" pilot program. Functional and psychosocial measures were conducted in person at six months; psychosocial measures and physical activity participation were assessed by telephone interview at 12 months. Ninety-five per cent were retained in the study at the six-month follow-up, and 88 per cent at 12 months...
January 4, 2017: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
https://www.readbyqxmd.com/read/28049201/a-pilot-randomized-controlled-trial-to-promote-immunosuppressant-adherence-in-adult-kidney-transplant-recipients
#14
Daniel Cukor, Nisha Ver Halen, Melissa Pencille, Fasika Tedla, Moro Salifu
BACKGROUND: Nonadherence to immunosuppressant medication is a prevalent practice among kidney transplant recipients and has been associated with increased risk for graft failure and economic burden. The aim of this pilot study was to test whether a culturally sensitive cognitive-behavioral adherence promotion program could significantly improve medication adherence to tacrolimus prescription as measured by telephone pill counts among kidney transplant recipients. METHODS: Thirty-three adult transplant recipients were less than 98% adherent to tacrolimus prescription based on 3 telephone pill counts and were randomized either to the 2-session cognitive-behavioral adherence promotion program or to standard care...
2017: Nephron
https://www.readbyqxmd.com/read/28047975/su-f-t-223-radiotherapy-incident-reporting-and-analysis-system-riras-early-experience
#15
R Kapoor, D Burkett, E Leidholdt, J Palta, M Hagan
BACKGROUND & PURPOSE: RIRAS is a web-based information system deployed on the Veterans Health Administration intranet in early 2014 to collect adverse events and good catch data; analyze the causes and contributing factors; and find ways to prevent future occurrences. MATERIAL AND METHODS: Incident learning consists of a feedback loop which starts with reporting an event, followed by analysis of contributing factors, and culminates in the development of a patient safety work product (PSWP) to prevent recurrence...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045934/priority-setting-for-novel-drug-regimens-to-treat-tuberculosis-an-epidemiologic-model
#16
Emily A Kendall, Sourya Shrestha, Ted Cohen, Eric Nuermberger, Kelly E Dooley, Lice Gonzalez-Angulo, Gavin J Churchyard, Payam Nahid, Michael L Rich, Cathy Bansbach, Thomas Forissier, Christian Lienhardt, David W Dowdy
BACKGROUND: Novel drug regimens are needed for tuberculosis (TB) treatment. New regimens aim to improve on characteristics such as duration, efficacy, and safety profile, but no single regimen is likely to be ideal in all respects. By linking these regimen characteristics to a novel regimen's ability to reduce TB incidence and mortality, we sought to prioritize regimen characteristics from a population-level perspective. METHODS AND FINDINGS: We developed a dynamic transmission model of multi-strain TB epidemics in hypothetical populations reflective of the epidemiological situations in India (primary analysis), South Africa, the Philippines, and Brazil...
January 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28034069/association-between-out-of-pocket-costs-race-ethnicity-and-adjuvant-endocrine-therapy-adherence-among-medicare-patients-with-breast-cancer
#17
Albert J Farias, Xianglin L Du
Purpose Previous studies suggest that adherence to adjuvant endocrine therapy (AET) for patients with breast cancer is suboptimal, especially among minorities, and is associated with out-of-pocket medication costs. This study aimed to determine whether there are racial/ethnic differences in 1-year adherence to AET and whether out-of-pocket costs explain the racial/ethnic disparities in adherence. Methods This retrospective cohort study used the SEER-Medicare linked database to identify patients ≥ 65 years of age with hormone receptor-positive breast cancer who were enrolled in Medicare Part D from 2007 to 2009...
January 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28033166/patient-characteristics-predictive-of-cardiac-rehabilitation-adherence
#18
Diann E Gaalema, Patrick D Savage, Jason L Rengo, Alex Y Cutler, Rebecca J Elliott, Jeffrey S Priest, Stephen T Higgins, Philip A Ades
PURPOSE: Cardiac rehabilitation (CR) is a program of structured exercise and interventions for coronary risk factor reduction that reduces morbidity and mortality rates following a major cardiac event. Although a dose-response relationship between the number of CR sessions completed and health outcomes has been demonstrated, adherence with CR is not high. In this study, we examined associations between the number of sessions completed within CR and patient demographics, clinical characteristics, smoking status, and socioeconomic status (SES)...
December 28, 2016: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28032940/the-relationship-between-risk-factors-and-medication-adherence-among-breast-cancer-survivors-what-explanatory-role-might-depression-play
#19
Louis C Markovitz, Nicholas J Drysdale, B Ann Bettencourt
OBJECTIVE: Despite the efficacy of clinical treatments (e.g., adjuvant hormonal therapy) for breast cancer survivors (BCS), nonadherence rates remains high, increasing the risk of recurrence and mortality. The current study tested a theoretical model of medical nonadherence that proposes depression to be the most proximal predictor of medical nonadherence among BCS. METHODS: BCS were recruited from radiation clinics in Missouri. Survey data were collected 12 months after the end of primary treatment...
December 29, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/28032073/the-effect-of-group-psychoeducation-program-on-medication-adherence-in-patients-with-bipolar-mood-disorders-a-randomized-controlled-trial
#20
Farnaz Rahmani, Hossein Ebrahimi, Fatemeh Ranjbar, Seyed Sajjad Razavi, Elnaz Asghari
Introduction: Medication nonadherence is highly prevalent in patients with bipolar disorders and often results in worsening disease prognosis. The purpose of this study was to investigate the effect of group psychoeducation on medication adherence in female patients with bipolar mood disorder type I. Methods: This randomized controlled trial was conducted on 76 patients with bipolar mood disorder admitted in female psychiatric wards of Razi teaching hospital, Tabriz, Iran. The participants were selected by convenience sampling method and were randomly assigned to experimental and control groups...
December 2016: Journal of Caring Sciences
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