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https://www.readbyqxmd.com/read/27824963/-18-f-fdg-pet-ct-can-differentiate-vertebral-metastases-from-schmorl-s-nodes-by-distribution-characteristics-of-the-18-f-fdg
#1
Zhengming Wang, Daqing Ma, Jigang Yang
BACKGROUND: Differentiation of vertebral metastases from Schmorl's nodes, especially with fluorine-18-fluorodeoxyglucose ((18)F-FDG) uptake, is very important for the appropriate management of these patients in case they have malignancy. We aimed to evaluate the value of (18)F-FDG positron emission tomography/computed tomography (PET/CT) in differentiating vertebral metastases from Schmorl's nodes with (18)F-FDG uptake. SUBJECTS AND METHODS: Fourteen patients with malignancy underwent (18)F-FDG PET/CT, which showed abnormal (18)F-FDG uptake in 19 Schmorl's nodes...
November 8, 2016: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/27690264/measurement-of-fat-content-in-vertebral-marrow-using-a-modified-dixon-sequence-to-differentiate-benign-from-malignant-processes
#2
Hye Jin Yoo, Sung Hwan Hong, Dong Hyun Kim, Ja-Young Choi, Hee Dong Chae, Bo Mi Jeong, Joong Mo Ahn, Heung Sik Kang
PURPOSE: To determine whether fat-signal-fraction (FF) map using a modified Dixon sequence could help differentiate benign from malignant bone lesions. MATERIALS AND METHODS: Spine magnetic resonance images (MRIs) of 120 consecutive patients were studied by using a 3T MRI with standard T1 -weighted image (T1 WI) and modified-Dixon sequence for FF measurement. There were three groups: a control group (n = 51) with normal vertebrae; a benign group (n = 40) with focal red marrow deposition, Schmorl's nodes, benign compression fracture, or Modic type 1 endplate degeneration; a malignant group (n = 29) with spinal malignancies...
September 30, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27513226/how-reliable-are-the-reported-genetic-associations-in-disc-degeneration-the-influence-of-phenotypes-age-population-size-and-inclusion-sequence-in-809-patients
#3
S Rajasekaran, Rishi Mugesh Kanna, Ranjani Raja Reddy, Senthil Natesan, Muthuraja Raveendran, Kenneth Mc Cheung, Danny Chan, Patrick Yp Kao, Anita Yee, Ajoy Prasad Shetty
STUDY DESIGN: Prospective genetic association study OBJECTIVE.: To document the variations in the genetic associations, when different MRI phenotypes, age stratification, cohort size and sequence of cohort inclusion are varied in the same study population. SUMMARY OF BACKGROUND DATA: Genetic associations with disc degeneration have shown high inconsistency, generally attributed to hereditary factors and ethnic variations. However the effect of different phenotypes, size of the study population, age of the cohort etc have not been documented clearly...
August 10, 2016: Spine
https://www.readbyqxmd.com/read/27480265/chronic-low-back-pain-in-relation-to-modic-changes-bony-endplate-lesions-and-disc-degeneration-in-a-prospective-mri-study
#4
Katariina Luoma, Tapio Vehmas, Liisa Kerttula, Mats Grönblad, Eeva Rinne
PURPOSE: To clarify the significance of Modic changes, bony endplate lesions, and disc degeneration as predictors of chronic low back pain (LBP) during 1-year follow-up. METHODS: 49 patients with severe, non-specific, chronic LBP, and Modic 1 lesion (M1) were prospectively studied with MRI and questionnaire. Changes in grade of disc degeneration, severity of Modic changes, Schmorl lesions, and bony endplate irregularities were evaluated and changes assessed in LBP intensity on numeric rating scale 0-10 and severity with Oswestry disability index 0-100 (ODI)...
September 2016: European Spine Journal
https://www.readbyqxmd.com/read/27455343/an-unusual-cause-of-back-pain-in-a-10-year-old-girl
#5
Stephen Michael Sandelich, Terry A Adirim
A 10-year-old girl with a 2-week history of atraumatic back pain presented to the emergency department with difficulty ambulating and a history of 2 episodes of urinary incontinence in the past week. Her examination was significant for pain with movement, tenderness to palpation in the lower thoracic spine, and no neurological deficits. In this case, the child was found to have a Schmorl node at T8 in the superior aspect of the vertebral body. Schmorl nodes are protrusions of the cartilage of the intervertebral disc through the vertebral body endplate and into the adjacent that is more commonly reported in the adult population...
July 23, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27437323/prevalence-and-clinical-relevance-of-schmorl-s-nodes-on-magnetic-resonance-imaging-in-a-tertiary-hospital-in-southern-india
#6
Devimeenal Jagannathan, Venkatraman Indiran, Fouzal Hithaya
INTRODUCTION: Schmorl's Nodes (SN), which appear as defects in superior and inferior endplates of vertebrae, are commonly seen around the thoracolumbar junction. They may be asymptomatic or symptomatic. Their prevalence varies with respect to age, gender, regions involved and other associated disc or vertebral findings. AIM: SN is quite a common finding on the Magnetic Resonance Imaging (MRI) of the spine. The purpose of the study was to evaluate the prevalence of SN in the patients who underwent MRI whole spine in the radiology department, ascertain its clinical relevance and to compare the prevalence of SN in the study population with the prevalence in rest of the Indian and global population described already in the literature...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27372375/presentation-and-medical-management-of-fibrocartilaginous-embolism-in-the-emergency-department
#7
Derick D Jones, Robert E Watson, Heather A Heaton
BACKGROUND: Fibrocartilaginous embolism is an exceedingly rare condition that was formerly a clinical diagnosis based on mechanism of injury, physical examination findings, and older magnetic resonance imaging (MRI) technologies without a specific histologic diagnosis. Spinal cord MRI diffusion-weighted imaging allows for a more specific diagnosis. CASE REPORT: A 14-year-old male felt a sudden pop in his back while running sprints in his gym class. He slowly developed bilateral lower extremity weakness and urinary incontinence, prompting an emergency department evaluation...
September 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27143364/classification-of-schmorl-s-nodes-of-the-lumbar-spine-and-association-with-disc-degeneration-a-large-scale-population-based-mri-study
#8
D Samartzis, F P S Mok, J Karppinen, D Y T Fong, K D K Luk, K M C Cheung
OBJECTIVE: Schmorl's nodes (SN) are highly associated with lumbar disc degeneration (DD). However, SN present with different morphologies/topographies that may be associated with varying degrees of DD. This study proposed a classification of SN to determine their morphological/topographical prevalence and association with the severity of DD. METHODS: Sagittal T2-weighted MRIs were assessed to identify SN and additional imaging findings from L1-S1 in 2,449 individuals...
October 2016: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/27134989/limbus-vertebra-presenting-with-inflammatory-low-back-pain-a-case-report
#9
Serpil Tuna, Tayfun Özdemir, Hande Ece Öz
Limbus vertebra is a condition characterized by marginal interosseous herniation of the nucleus pulposus, and causes non specific symptoms like low back pain, back pain, muscle spasms and radiculopathy. It is frequently confused with vertebral fracture, infection, schmorl nodule or tumour because it has not a spesific symptom. It usually causes mechanical low back pain rather than inflammatory low back pain. We reported a patient presented with inflammatory low back pain and diagnosed with anterior limbus vertebra because it is rare and the patient has atypical clinical presentation...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27082664/uncommon-manifestations-of-intervertebral-disk-pathologic-conditions
#10
Felix E Diehn, Timothy P Maus, Jonathan M Morris, Carrie M Carr, Amy L Kotsenas, Patrick H Luetmer, Vance T Lehman, Kent R Thielen, Ahmad Nassr, John T Wald
Beyond the familiar disk herniations with typical clinical features, intervertebral disk pathologic conditions can have a wide spectrum of imaging and clinical manifestations. The goal of this review is to illustrate and discuss unusual manifestations of intervertebral disk pathologic conditions that radiologists may encounter, including disk herniations in unusual locations, those with atypical imaging features, and those with uncommon pathophysiologic findings. Examples of atypical disk herniations presented include dorsal epidural, intradural, symptomatic thoracic (including giant calcified), extreme lateral (retroperitoneal), fluorine 18 fluorodeoxyglucose-avid, acute intravertebral (Schmorl node), and massive lumbar disk herniations...
May 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/26984710/morpho-histology-of-head-kidney-of-female-catfish-heteropneustes-fossilis-seasonal-variations-in-melano-macrophage-centers-melanin-contents-and-effects-of-lipopolysaccharide-and-dexamethasone-on-melanins
#11
Ravi Kumar, K P Joy, S M Singh
In the catfish Heteropneustes fossilis, the anterior kidney is a hemopoietic tissue which surrounds the adrenal homologues, interrenal (IR) and chromaffin tissues corresponding to the adrenal cortical and adrenal medulla of higher mammals. The IR tissue is arranged in cell cords around the posterior cardinal vein (PCV) and its tributaries and secretes corticosteroids. The chromaffin tissue is scattered singly or in nests of one or more cells around the epithelial lining of the PCV or blood capillaries within the IR tissue...
October 2016: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/26947187/mr-imaging-of-schmorl-s-nodes-imaging-characteristics-and-epidemio-clinical-relationships
#12
M Moustarhfir, B Bresson, P Koch, A Perozziello, G Barreau, E Schouman-Claeys, M-C Henry-Feugeas, P Ou, B Dallaudière
PURPOSE: The purpose of our prospective study was to assess the presentation of Schmorl's nodes (SN) on magnetic resonance imaging (MRI) and investigate their possible association with demographic and clinical findings. MATERIALS AND METHODS: Three hundred and thirty-three patients were prospectively included. Thirteen (3.9%) patients were excluded because of contraindication to MRI and/or Scheuermann's disease. The final study population included 320 patients. T1-weighted and short TI inversion recovery sequences were performed to assess SN prevalence, the vertebral level and their anatomical distribution in vertebra...
April 2016: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/26911278/correlation-between-degenerative-spine-disease-and-bone-marrow-density-a-retrospective-investigation
#13
Astrid Ellen Grams, Rafael Rehwald, Alexander Bartsch, Sarah Honold, Christian Franz Freyschlag, Michael Knoflach, Elke Ruth Gizewski, Bernhard Glodny
BACKGROUND: Spondylosis leads to an overestimation of bone mineral density (BMD) with dual-energy x-ray absorptiometry (DXA) but not with quantitative computed tomography (QCT). The correlation between degenerative changes of the spine and QCT-BMD was therefore investigated for the first time. METHODS: One hundred thirty-four patients (66 female and 68 male) with a mean age of 49.0 ± 14.6 years (range: 19-88 years) who received a CT scan and QCT-BMD measurements of spine and hip were evaluated retrospectively...
February 24, 2016: BMC Medical Imaging
https://www.readbyqxmd.com/read/26906040/unique-anisotropic-optical-properties-of-a-highly-stable-metal-organic-framework-based-on-trinuclear-iron-iii-secondary-building-units-linked-by-tetracarboxylic-linkers-with-an-anthracene-core
#14
A V Vinogradov, V A Milichko, H Zaake-Hertling, A Aleksovska, S Gruschinski, S Schmorl, B Kersting, E M Zolnhofer, J Sutter, K Meyer, P Lönnecke, E Hey-Hawkins
A highly stable metal-organic framework, [{Fe3(ACTBA)2}X·6DEF]n (1; X = monoanion), based on trinuclear iron(iii) secondary building units connected by tetracarboxylates with an anthracene core, 2,6,9,10-tetrakis(p-carboxylatophenyl)anthracene (ACTBA), is reported. Depending on the direction of light polarisation, crystals of 1 exhibit anisotropic optical properties with birefringence Δn = 0.3 (λ = 590 nm).
May 7, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/26852295/on-endocytosis-of-foreign-ferritin-and-occurrence-of-phagolysosomes-in-fish-heart-endothelial-cells
#15
Ingvar Leiv Leknes
In the present study the ultrastructure and function of the endothelial cells enveloping the muscle trabeculae in heart in two teleosts, platyfish and firemouth cichlid, are described and discussed. These cells displayed a structure making them able to take up large amounts of foreign ferritin particles from the blood stream. The ferritin particles were assembled into huge phagolysosomes. Large amounts of Prussian blue were precipitated throughout these lysosomes when treated with acid ferrohexacyanide solution...
April 2016: Acta Histochemica
https://www.readbyqxmd.com/read/26778820/painful-lumbar-schmorl-nodule-mimicking-osteoma-osteoid
#16
Guilherme Lucas de Oliveira Lima, Eduardo Ernesto Pelinca da Costa
No abstract text is available yet for this article.
July 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/26746783/spinal-cord-stroke-presenting-with-acute-monoplegia-in-a-17-year-old-tennis-player
#17
Julie A Nelson, Chang Y Ho, Meredith R Golomb
BACKGROUND: Acute monoplegia is a rare presentation for spinal cord stroke, which usually presents with paraplegia or paraparesis. PATIENT DESCRIPTION: We describe an athletic girl who presented after a week of heavy athletic activity complaining of back and left leg pain, followed by flaccid left leg paralysis. RESULTS: The prothrombotic evaluation was unremarkable. Cerebrospinal fluid studies demonstrated elevated myelin basic protein but no oligoclonal bands...
March 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/26562580/schmorl-nodes-can-cause-increased-68ga-dotatate-activity-on-pet-ct-mimicking-metastasis-in-patients-with-neuroendocrine-malignancy
#18
Georgios Z Papadakis, Corina Millo, Ulas Bagci, Samira M Sadowski, Constantine A Stratakis
Schmorl node (SN) is the herniation of the nucleus pulposus through the cartilaginous and bony endplate into the adjacent vertebral body. It is documented that SNs produce areas of moderately increased F-FDG uptake. We present a case of a patient with history of neuroendocrine tumor, who underwent Ga DOTATATE PET/CT for follow-up, showing increased focal vertebral uptake suggestive of bone metastasis. CT revealed typical findings of an SN. The presented case indicates that SNs should be considered when encountering focally increased skeletal uptake in Ga DOTATATE PET/CT studies, which can mimic metastasis in patients with history of neuroendocrine tumors...
March 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/26456851/modic-changes-of-the-lumbar-spine-prevalence-risk-factors-and-association-with-disc-degeneration-and-low-back-pain-in-a-large-scale-population-based-cohort
#19
Florence P S Mok, Dino Samartzis, Jaro Karppinen, Daniel Y T Fong, Keith D K Luk, Kenneth M C Cheung
BACKGROUND CONTEXT: Modic changes (MC) are bone marrow lesions on magnetic resonance imaging (MRI), suggestive of being associated with low back pain (LBP). Data on determinants of MC and their association with disc degeneration and other spinal phenotypes, as well as that of LBP, rely mostly on small-scale patient populations and remain controversial. PURPOSE: This study addressed the potential determinants of MC and their association with disc degeneration and LBP among Southern Chinese...
January 1, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/26361533/complete-separation-of-the-vertebral-body-associated-with-a-schmorl-s-node-accompanying-severe-osteoporosis
#20
Seon Joo Park, Hyeun Sung Kim, Hyun Sook Kim, Seok Won Kim
A Schmorl's node is defined as a simple endplate intravertebral herniation resulting from trauma or idiopathic causes. Although Schmorl's nodes have been considered clinically insignificant, they might indicate an active symptomatic process or cause serious complications. In this study, we report an interesting case of complete separation of a vertebral body caused by an untreated Schmorl's node accompanying severe osteoporosis. To our knowledge, this is the first clinical report in the published literature to evaluate the complete separation of a vertebral body associated with a Schmorl's node...
August 2015: Journal of Korean Neurosurgical Society
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