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cavia porcellus

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https://www.readbyqxmd.com/read/28631164/studies-on-vertical-transmission-of-trichinella-spiralis-in-experimentally-infected-guinea-pigs-cavia-porcellus
#1
Eliana Riva, Cesar Fiel, Gisele Bernat, Sebastián Muchiut, Pedro Steffan
An experimental study to enhance knowledge on the capability of Trichenella spiralis to pass from guinea pigs to progeny at different periods of pregnancy or lactation was performed. For this purpose, 18 female adult guinea pigs were inoculated with 100 or 1000 T. spiralis muscle larvae (ML) during early, late gestation and during lactation period. The presence of T. spiralis (ML) in mothers and newborns was studied through enzymatic digestion from muscle samples. ML were observed in 9 of 42 newborn guinea pigs and levels of infection were significantly higher when infections of mothers were done during late gestation (p = 0...
June 19, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28621258/evaluation-of-pain-assessment-techniques-and-analgesia-efficacy-in-a-female-guinea-pig-cavia-porcellus-model-of-surgical-pain
#2
Vanessa L Oliver, Stephanie Athavale, Katherine E Simon, Lon V Kendall, Jean A Nemzek, Jennifer L Lofgren
Guinea pigs (Cavia porcellus) are a frequently used species in research, often involving potentially painful procedures.Therefore, evidence-based recommendations regarding analgesia are critically needed to optimize their wellbeing. Ourlaboratory examined the efficacy of carprofen and extended-release (ER) buprenorphine, alone and as a multimodal combination,for relieving postsurgical pain in guinea pigs. Animals were assessed by using evoked (mechanical hypersensitivity),nonevoked (video ethogram, cageside ethogram, time-to-consumption test), and clinical (weight loss) measurements for 96 h during baseline, anesthesia-analgesia, and hysterectomy conditions...
June 15, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28525336/accuracy-of-real-time-shear-wave-elastography-in-the-assessment-of-normal-liver-tissue-in-the-guinea-pig-cavia-porcellus
#3
K Glińska-Suchocka, K Kubiak, J Spużak, M Jankowski, P Borusewicz
Shear wave elastography is a novel technique enabling real-time measurement of the elasticity of liver tissue. The color map is superimposed on the classic ultrasound image of the assessed tissue, which enables a precise evaluation of the stiffness of the liver tissue. The aim of the study was to assess the stiffness of normal liver tissue in the guinea pig using shear wave elastography. The study was carried out on 36 guinea pigs using the SuperSonic Imagine Aixplorer scanner, and a 1 to 6 MH convex SC6-1 transducer...
March 28, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28516833/animal-models-of-ebolavirus-infection
#4
Marisa C St Claire, Dan R Ragland, Laura Bollinger, Peter B Jahrling
Ebola virus is a highly pathogenic member of the family Filoviridae that causes a severe hemorrhagic disease in humansand NHP. The 2013-2016 West African outbreak has increased interest in the development and refinement of animal models of Ebola virus disease. These models are used to test countermeasures and vaccines, gain scientific insights into the mechanisms of disease progression and transmission, and study key correlates of immunology. Ebola virus is classified as a BSL4 pathogen and Category A agent, for which the United States government requires preparedness in case of bioterrorism...
May 17, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28493036/life-cycle-of-amblyomma-oblongoguttatum-acari-ixodidae-under-laboratory-conditions
#5
Thiago F Martins, Hermes R Luz, João Luiz H Faccini, Marcelo B Labruna
This study evaluated for the first time the life cycle of Amblyomma oblongoguttatum in the laboratory. For this purpose, larvae and nymphs were exposed to Gallus gallus (chicks), Rattus norvegicus (wistar rat), Calomys callosus (vesper mouse), Oryctolagus cuniculus (domestic rabbit), Cavia porcellus (guinea pig), and Didelphis albiventris (white-eared opossum). Nymphs were exposed to G. gallus, C. callosus, C. porcellus, O. cuniculus, R. norvegicus, and Nectomys squamipes (water rat). Adult ticks were exposed to domestic dogs...
May 10, 2017: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/28438110/temporal-progression-of-lesions-in-guinea-pigs-infected-with-lassa-virus
#6
T M Bell, C I Shaia, J J Bearss, M E Mattix, K A Koistinen, S P Honnold, X Zeng, C D Blancett, G C Donnelly, J D Shamblin, E R Wilkinson, K A Cashman
Lassa virus (LASV) infection causes an acute, multisystemic viral hemorrhagic fever that annually infects an estimated 100 000 to 300 000 persons in West Africa. This pathogenesis study evaluated the temporal progression of disease in guinea pigs following aerosol and subcutaneous inoculation of the Josiah strain of LASV as well as the usefulness of Strain 13 guinea pigs as an animal model for Lassa fever. After experimental infection, guinea pigs ( Cavia porcellus; n = 67) were serially sampled to evaluate the temporal progression of infection, gross and histologic lesions, and serum chemistry and hematologic changes...
May 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28427752/spontaneously-arising-tumours-and-tumour-like-lesions-of-the-cervix-and-uterus-in-83-pet-guinea-pigs-cavia-porcellus
#7
C Laik-Schandelmaier, R Klopfleisch, S Schöniger, G Weiffenbach, M Staudacher, H Aupperle
Tumours and tumour-like lesions are rare findings in the genital system of guinea pigs. The aim of the present study was to characterize nodular lesions in the cervix and uterus of guinea pigs submitted for histopathological diagnosis. Samples from 83 pet animals were investigated. Cases included 64 surgically excised masses including complete uteri (n = 37), parts from uteri containing masses (n = 8), complete masses (n = 12) or samples from masses (n = 7) and 19 complete necropsy examinations. In 55 of the cases, only solitary changes were observed; in 28 cases two or more lesions were diagnosed...
April 17, 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28425214/hypoglycemic-and-antihyperglycemic-activities-of-nine-medicinal-herbs-used-as-antidiabetic-in-the-region-of-lubumbashi-dr-congo
#8
Bakari Amuri, Mwamba Maseho, Lumbu Simbi, Philippe Okusa, Pierre Duez, Kahumba Byanga
The aim of this study was to assess the hypoglycemic and antihyperglycemic activities of nine plants used as antidiabetic treatments in Lubumbashi and its surroundings. Those are Albizia adianthifolia, Azanza garckeana, Cassia occidentalis, Cassia sieberiana, Erythrina abyssinica, Gladiolus klattianus, Rauvolfia caffra, Strychnos spinosa, and Vitex madiensis. Aqueous extracts, obtained by decoction and maceration, were administered (500 mg/kg) per os to guinea pigs (Cavia porcellus), both in glucose baseline conditions and in oral glucose tolerance test (OGTT) conditions (glucose, 2 g/kg; follow-up over 210 min)...
April 20, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28344561/fetal-growth-restriction-induces-heterogeneous-effects-on-vascular-biomechanical-and-functional-properties-in-guinea-pigs-cavia-porcellus
#9
Daniel Cañas, Emilio A Herrera, Claudio García-Herrera, Diego Celentano, Bernardo J Krause
Aim: Fetal growth restriction (FGR) is associated with a variety of cardiometabolic diseases in adulthood which could involve remodeling processes of the vascular walls that could start in the fetal period. However, there is no consensus whether this remodeling affects in a similar way the whole vascular system. We aimed to determine the effects of FGR on the vasoactive and biomechanical properties of umbilical and systemic vessels in fetal guinea pigs. Methods: FGR was induced by implanting ameroid occluders at mid-gestation in uterine arteries of pregnant guinea pigs, whilst the control group was exposed to simulated surgery...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28328950/repeated-anaesthesia-with-isoflurane-and-medetomidine-midazolam-fentanyl-in-guinea-pigs-and-its-influence-on-physiological-parameters
#10
Sabrina Schmitz, Sabine Tacke, Brian Guth, Julia Henke
Repeated anaesthesia may be required in experimental protocols and in daily veterinary practice, but anaesthesia is known to alter physiological parameters in GPs (Cavia porcellus, GPs). This study investigated the effects of repeated anaesthesia with either medetomidine-midazolam-fentanyl (MMF) or isoflurane (Iso) on physiological parameters in the GP. Twelve GPs were repeatedly administered with MMF or Iso in two anaesthesia sets. One set consisted of six 40-min anaesthesias, performed over 3 weeks (2 per week); the anaesthetic used first was randomized...
2017: PloS One
https://www.readbyqxmd.com/read/28166947/effects-of-heat-stress-on-some-reproductive-parameters-of-male-cavie-cavia-porcellus-and-mitigation-strategies-using-guava-psidium-guajava-leaves-essential-oil
#11
Ferdinand Ngoula, Maryvonne Guemdjo Tekam, Augustave Kenfack, Cyrille D'Alex Tadondjou Tchingo, Sandrine Nouboudem, Herman Ngoumtsop, Borice Tsafack, Alexis Teguia, Pierre Kamtchouing, Marco Galeotti, Joseph Tchoumboue
Climate changes, particularly the increase of temperature are among the main causes behind the decline of fertility in humans as well as animals. In this study, the effects of heat stress on some reproductive parameters of male cavies and mitigation strategies using guava leaves essential oil (GLEO) were studied. For this purpose, 40 male cavies aged 2.5-3 months and weighing between 348 and 446g were divided into 4 groups of 10 animals each and subjected to the following temperatures: Ambient temperature (20-25°C) for the control group, 35°C for group 1, 45°C for group 2 and 45°C+100µl GLEO/kg body weight, administered by gavage to animals for group 3...
February 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28064023/identification-and-characterization-of-a-gamma-interferon-inducible-lysosomal-thiol-reductase-homolog-from-guinea-pig-cavia-porcellus-that-exhibits-thiol-reductase-activity-in-vitro
#12
Lei Ma, Fang Cao, Runze Tang, Jiaxin Zhang, Shuangquan Zhang
Gamma-interferon-inducible lysosomal thiol reductase (GILT) is a key enzyme in the antigen processing and presentation pathway whereby it reduces disulfide bonds at an acidic pH. In this study, a homolog of GILT from guinea pigs (designated gpGILT) was identified and characterized using bioinformatic methods and bioactivity assays. The open reading frame of gpGILT is 705bp in length and encodes 234 amino acids, with a putative molecular weight of about 25.85kDa. The structure of gpGILT is similar to those of humans and zebrafish, containing six introns and seven exons...
April 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28008820/streptococcus-caviae-sp-nov-isolated-from-guinea-pig-faecal-samples
#13
Susakul Palakawong Na Ayudthaya, Loes J Hilderink, John van der Oost, Willem M de Vos, Caroline M Plugge
A novel cellobiose-degrading and lactate-producing bacterium, strain Cavy grass 6T, was isolated from faecal samples of guinea pigs (Cavia porcellus). Cells of the strain are oval-shaped, non-motile, non-spore-forming, stain Gram-positive and facultative anaerobic. The strain grows between 25 - 40oC (optimum is 37oC) and pH 4.5 - 9.5 (optimum is 8.0). Phylogenetic analysis based on 16S rRNA gene sequence showed that strain Cavy grass 6T belongs to the genus Streptococcus with its closest relative being Streptococcus devriesei CCUG 47155T with only 96...
December 23, 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/27931318/pharmacokinetics-and-paw-withdrawal-pressure-in-female-guinea-pigs-cavia-porcellus-treated-with-sustained-release-buprenorphine-and-buprenorphine-hydrochloride
#14
Brian J Smith, Daniel J Wegenast, Ryan J Hansen, Ann M Hess, Lon V Kendall
Providing appropriate analgesia is essential in minimizing pain and maintaining optimal animal care and welfare in laboratory animals. Guinea pigs are common animal models in biomedical research, often requiring analgesic support. Here we evaluated the pharmacokinetics and efficacy of a sustained-release formulation of buprenorphine (Bup-SR) in this species. Guinea pigs (n = 7 each group) received either Bup-HCl (0.05 mg/kg BID for 3 d) or Bup-SR (0.3 mg/kg once). Plasma collection and measurement of paw-withdrawal pressure (PWP) was conducted at 0, 1, 3, 6, 12, 26, 48, and 72 h after treatment...
November 2016: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/27901456/partial-gastrectomy-for-resection-of-a-gastric-leiomyoma-in-a-guinea-pig-cavia-porcellus
#15
Sara M Gardhouse, David Sanchez-Migallon Guzman, Miranda J Sadar, Anthony J DeRouen, Daniel S Bucy, Adeyemi O Adedeji, William Vernau, Kerriann M Casey, F Charles Mohr, Michele A Steffey
CASE DESCRIPTION A 4-year-old sexually intact male pet guinea pig (Cavia porcellus) was evaluated for a routine wellness examination. CLINICAL FINDINGS During physical examination, a small mass was palpated in the cranial aspect of the abdomen. Abdominal radiographic and ultrasonographic findings were suggestive of a gastric mass. Cytologic evaluation of a fine-needle aspirate of the mass was indicative of spindle cell proliferation most consistent with a sarcoma. TREATMENT AND OUTCOME The patient was anesthetized, and an exploratory laparotomy and partial gastrectomy were performed to resect the gastric mass...
December 15, 2016: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/27876917/treatment-and-control-of-trixacarus-caviae-infestation-in-a-conventional-guinea-pig-cavia-porcellus-breeding-colony
#16
Anjan Jyoti Nath
A case of sarcoptic mange caused by Trixacarus caviae in a conventional guinea pig breeding colony is reported. The infestation was reported in a large colony of guinea pigs during the month of July, 2013 affecting 30 breeder guinea pigs. Severely infested animals were treated individually with subcutaneous injection of ivermectin 1 % w/v (Neomec(®)) at the rate of 400 µg/kg body weight 10 days apart. Three doses of ivermectin were sufficient to eliminate the parasite which tested negative after 30 days of the first treatment...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27854241/an-investigation-into-the-relationship-between-owner-knowledge-diet-and-dental-disease-in-guinea-pigs-cavia-porcellus
#17
Rosemary Norman, Alison P Wills
Recent studies have highlighted a high prevalence of dental disease in domestic guinea pigs, yet the aetiology of this multi-factorial disease is still unclear. Factors that have been associated with dental disease include feeding a diet that is high in energy but low in fibre, feeding an insufficiently abrasive diet, a lack of dietary calcium, and genetics. As many of these factors relate to the husbandry requirements of guinea pigs, owner awareness of dietary requirements is of the utmost importance. An online questionnaire was created based on previous research into the husbandry and feeding of rabbits...
November 14, 2016: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/27779826/mystacial-whisker-layout-and-musculature-in-the-guinea-pig-cavia-porcellus-a-social-diurnal-mammal
#18
Robyn A Grant, Mariane G Delaunay, Sebastian Haidarliu
All mammals (apart from apes and humans) have whiskers that make use of a similar muscle arrangement. Whisker specialists, such as rats and mice, tend to be nocturnal and arboreal, relying on their whisker sense of touch to guide exploration around tree canopies at night. As such, nocturnal arboreal rodents have many whiskers that are organised into a grid-like pattern, and moved using a complex array of muscles. Indeed, most arboreal, nocturnal mammals tend to have specialised whiskers that are longer and arranged in a dense, regular grid, compared to terrestrial, diurnal mammals...
October 25, 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/27771802/evaluation-of-the-infectivity-and-the-persistence-of-trichinella-patagoniensis-in-muscle-tissue-of-decomposing-guinea-pig-cavia-porcellus
#19
F Fariña, M Pasqualetti, J Ilgová, N Cardillo, M Ercole, T Aronowicz, S Krivokapich, M Kašný, M Ribicich
Trichinella patagoniensis, a new species of Trichinella, is widespread in Argentina. The success of parasite transmission depends, among other factors, on the resistance of L1 larvae present in the muscle tissue (ML) of dead hosts undergoing the decomposition process in different environmental conditions. The aim of the present work was to study the infectivity of T. patagoniensis muscle larvae in Cavia porcellus and the capability of the parasite to survive in decomposed muscle tissue of guinea pigs subjected to different environmental conditions...
January 2017: Parasitology Research
https://www.readbyqxmd.com/read/27730208/morphometric-evaluation-of-wound-healing-in-burns-treated-with-ulmo-eucryphia-cordifolia-honey-alone-and-supplemented-with-ascorbic-acid-in-guinea-pig-cavia-porcellus
#20
Carolina Schencke, Adriana Vasconcellos, Cristian Sandoval, Paulina Torres, Francisca Acevedo, Mariano Del Sol
BACKGROUND: In the context of the search for cost-efficient treatments, Ulmo (Eurcyphia cordifolia) honey is an excellent alternative for treating burn wounds and could have a profound medical, social, and economic impact. Ascorbic acid is an enzymatic co-factor necessary for the synthesis of collagen and the proliferation of fibroblasts and has been proposed as a coadjuvant to strengthen the healing effects of honey. The aim of this work was to evaluate by morphometric studies the healing wounds caused by burns treated with Ulmo honey alone and supplemented with ascorbic acid in guinea pig (Cavia porcellus)...
2016: Burns and trauma
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