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https://www.readbyqxmd.com/read/28642700/pricing-and-reimbursement-of-biosimilars-in-central-and-eastern-european-countries
#1
Paweł Kawalec, Ewa Stawowczyk, Tomas Tesar, Jana Skoupa, Adina Turcu-Stiolica, Maria Dimitrova, Guenka I Petrova, Zinta Rugaja, Agnes Männik, Andras Harsanyi, Pero Draganic
Objectives: The aim of this study was to review the requirements for the reimbursement of biosimilars and to compare the reimbursement status, market share, and reimbursement costs of biosimilars in selected Central and Eastern European (CEE) countries. Methods: A questionnaire-based survey was conducted between November 2016 and January 2017 among experts from the following CEE countries: Bulgaria, Czech Republic, Croatia, Estonia, Hungary, Latvia, Lithuania, Poland, Slovakia, and Romania. The requirements for the pricing and reimbursement of biosimilars were reviewed for each country...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28639115/chemical-composition-of-selected-commercial-herbal-remedies-in-relation-to-geographical-origin-and-inter-species-diversity
#2
Pawel Konieczynski, Agnieszka Viapiana, Roman Lysiuk, Marek Wesolowski
Infusions prepared from medicinal herbs that are rich in flavonoids are very popular herbal remedies in societies of Eastern Europe. Therefore, the content of essential elements together with total flavonoids was analyzed in 65 commercially available samples of herbal drugs originating from Ukraine, Romania, and Belarus. The results showed that metallic elements (in mg kg(-1) d.w.) have occurred in the following order: Fe > Mn > Zn > Cu, both for total and water-extractable species. Total flavonoids were determined in the range from 10...
June 21, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28637524/a-new-look-at-the-supposed-risks-of-early-institutional-rearing
#3
S Woodhouse, A Miah, M Rutter
The main focus is on the assessment of the effects of early institutional care and compares three longitudinal studies from Romania, Greece and Hong Kong/China. The findings have been strikingly contrasting. The review asks if the risks are dependent on whether or not the institutional rearing is accompanied by gross pervasive deprivation (as it was in Romania) and investigates the methodological issues to explore the causal influence of the outcomes. Evidence is considered on changing institutional practices and the benefits of doing so...
June 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28636649/factors-associated-with-successful-transition-among-children-with-disabilities-in-eight-european-countries
#4
John Ravenscroft, Kerri Wazny, John M Davis
INTRODUCTION: This research paper aims to assess factors reported by parents associated with the successful transition of children with complex additional support requirements that have undergone a transition between school environments from 8 European Union member states. METHODS: Quantitative data were collected from 306 parents within education systems from 8 EU member states (Bulgaria, Cyprus, Greece, Ireland, the Netherlands, Romania, Spain and the UK). The data were derived from an online questionnaire and consisted of 41 questions...
2017: PloS One
https://www.readbyqxmd.com/read/28636570/use-of-electroconvulsive-therapy-in-central-eastern-european-countries-an-overview
#5
Gábor Gazdag, Jozef Dragasek, Rozália Takács, Margus Lõokene, Tomasz Sobow, Aleksey Olekseev, Gabor S Ungvari
Though a number of reports on the use of electroconvulsive therapy (ECT) has been published from the Central-Eastern European region over the past two decades, a systematic review of this literature has not been published. Thus the aim of this paper was to review recent trends in ECT practice in Central-Eastern Europe. Systematic literature search was undertaken using the Medline, PSYCHINFO and EMBASE databases covering the period between January 2000 and December 2013. Relevant publications were found from the following countries: Bulgaria, Croatia, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania, Serbia, Slovakia, Ukraine, but none from Albania and Moldova...
June 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28634569/epidemiology-and-management-of-atrial-fibrillation-and-stroke-review-of-data-from-four-european-countries
#6
REVIEW
Andreea D Ceornodolea, Roland Bal, Johan L Severens
In Europe, 1-3% of the population suffers from atrial fibrillation (AF) and has increased stroke risk. By 2060 a doubling in number of cases and great burden in managing this medical condition are expected. This paper offers an overview of data on epidemiology and management of AF and stroke in four European countries as well as the interconnection between these dimensions. A search index was developed to access multiple scientific and "grey" literatures. Information was prioritised based on strength of evidence and date...
2017: Stroke Research and Treatment
https://www.readbyqxmd.com/read/28631287/incidental-findings-of-implant-complications-on-postimplantation-cbcts-a-cross-sectional-study
#7
Danielle Clark, Horia Barbu, Adi Lorean, Eitan Mijiritsky, Liran Levin
BACKGROUND: Survival rates of dental implants are reported to be very high and seem to indicate minimal complications related to dental implants. PURPOSE: The aim of this report was to evaluate in a cross-sectional study the prevalence of implant positioning complications as appears in postimplantation Cone-Beam Computerized Tomography (CBCT) in two of the major imaging facilities in Bucharest, Romania. METHODS: Demographic and implant data was collected from two of the three main CBCT facilities in Bucharest, Romania...
June 20, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28617888/position-paper-on-treatment-of-hepatitis-c-in-romania-2017-part-one
#8
Liana Gheorghe, Ioan Sporea, Speranţa Iacob, Roxana Şirli, Anca Trifan, Daniela Dobru, Mircea Diculescu, Carol Stanciu, Oliviu Pascu, Monica Acalovschi, Ciprian Brisc, Cristina Cijevschi, Cristian Gheorghe, Zeno Spârchez, Ion Rogoveanu, Dan Dumitrascu
BACKGROUND AND AIMS: Hepatitis C Virus (HCV) infection is a common condition with endemic prevalence in some areas of the world. In Romania the mean prevalence is about 3%. New treatments became available on the market in recent years and new drugs are in the pipeline. A re-evaluation of HCV therapy was considered mandatory. The Romanian Society of Gastroenterology and Hepatology undertook this task for the practitioners of this country. METHODOLOGY: A group of recognized experts was created who screened the available literature and the major available guidelines...
June 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/28616091/price-and-distribution-policies-in-healthcare-marketing-in-romania
#9
B I Coculescu, E C Coculescu, V L Purcărea
There is a principle similar to the theory of exchange in the marketing of health services, meaning that what is delivered to the target market (i.e. the beneficiaries) must be equal to or greater than what is to be received (i.e. the price). The price level in the marketing mix is influenced by how the consumer perceives the respective medical service and is quantified in the profit and the turnover of the organization respectively. The cost of the medical act as a whole is the value of all the tangible and intangible variables associated with it, and the planning, distribution and promotion of the product must be taken into account in the price setting...
April 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28606177/recent-household-transmission-of-tuberculosis-in-england-2010-2012-retrospective-national-cohort-study-combining-epidemiological-and-molecular-strain-typing-data
#10
Maeve K Lalor, Laura F Anderson, Esther L Hamblion, Andy Burkitt, Jennifer A Davidson, Helen Maguire, Ibrahim Abubakar, H Lucy Thomas
BACKGROUND: We estimate the proportion of tuberculosis (TB) in England due to recent household transmission, identify factors associated with being a household transmitter, and investigate the impact that identification of a case has on time to treatment of subsequent cases. METHODS: TB cases notified between 2010 and 2012 in England in the same household as another case were identified; 24 locus MIRU-VNTR strain typing (ST) was used to identify household cases with likely recent transmission...
June 13, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28604626/presence-of-enniatins-and-beauvericin-in-romanian-wheat-samples-from-raw-material-to-products-for-direct-human-consumption
#11
Oana Stanciu, Cristina Juan, Doina Miere, Felicia Loghin, Jordi Mañes
In this study, a total of 244 wheat and wheat-based products collected from Romania were analyzed by liquid chromatography tandem mass spectrometry (LC-MS/MS) in order to evaluate the presence of four enniatins (ENs; i.e., ENA, ENA1, ENB, and ENB1) and beauvericin (BEA). For the wheat samples, the influence of agricultural practices was assessed, whereas the results for the wheat-based products were used to calculate the estimated daily intake of emerging mycotoxins through wheat consumption for the Romanian population...
June 12, 2017: Toxins
https://www.readbyqxmd.com/read/28604300/t-georgescu-the-eugenic-fortress-the-transylvanian-saxon-experiment-in-interwar%C3%A2-romania-budapest-ceu-press-2016-pp-x-279-55-00-hardback-isbn-%C3%A2-9789633861394
#12
https://www.readbyqxmd.com/read/28600748/teacher-respiratory-health-symptoms-in-relation-to-school-and-home-environment
#13
Shao Lin, Wayne R Lawrence, Ziqiang Lin, Melissa Francois, Iulia A Neamtiu, Qiaoxuan Lin, Eva Csobod, Eugen S Gurzau
PURPOSE: Few studies have evaluated teachers' respiratory health, especially its relationship with school/home environment, and school policies. This study assessed asthma and smoking prevalence among teachers in Romania, teacher's perception and knowledge of the school environment, policies and asthma management, and how school and home environment affected asthma, allergy, and respiratory infection symptoms. METHODS: This cross-sectional study obtained information from 104 Romanian teachers utilizing teacher questionnaire data for Romania only, as part of the Schools Indoor Pollution and Health: Observatory Network in Europe (SINPHONIE) study, a multicenter European research project conducted between 2010 and 2012...
June 9, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28595498/associations-of-smoking-with-cardiometabolic-profile-and-renal-function-in-a-romanian-population-based-sample-from-the-predatorr-cross-sectional-study
#14
Simona Georgiana Popa, Maria Moţa, Florin Dumitru Mihălţan, Adina Popa, Ioana Munteanu, Eugen Moţa, Cristian Serafinceanu, Cristian Guja, Nicolae Hâncu, Doina Catrinoiu, Radu Lichiardopol, Cornelia Bala, Bogdan Mihai, Gabriela Radulian, Gabriela Roman, Romulus Timar
BACKGROUND: The impact of smoking on morbidity is well known, but in Romania, limited data are available regarding the smoking prevalence and relationship with cardiometabolic profile and kidney function. OBJECTIVES: To assess the association of smoking with cardiometabolic traits and kidney function, in a Romanian population-based sample from the PREDATORR study. METHODS: PREDATORR was an epidemiological cross-sectional study. Between 2012 and 2014, participants were randomly selected from the lists of general practitioners and enrolled if they were aged 20 to 79 years, born and living in the past 10 years in Romania...
December 2017: European Journal of General Practice
https://www.readbyqxmd.com/read/28595462/isotopic-and-multielemental-fingerprinting-of-organically-and-conventionally-grown-potatoes
#15
Dana Alina Magdas, Adriana Dehelean, Ioana Feher, Stelian Radu
Two marker combinations were used for the differentiation of organically produced from conventionally produced potatoes and also for the geographical origin identification. Fifty-seven samples (from Romanian local producers or imported) were analysed from the stable isotopic (isotope ratio mass spectrometry) and elemental profile (inductively coupled plasma mass spectrometry) point of view. In order to assess the best marker combination, both isotopic and elemental experimental results were subject to chemometric analysis...
June 8, 2017: Isotopes in Environmental and Health Studies
https://www.readbyqxmd.com/read/28593978/romania-s-science-reforms-prompt-boycott
#16
Inga Vesper
No abstract text is available yet for this article.
June 6, 2017: Nature
https://www.readbyqxmd.com/read/28587094/burnout-and-its-relationships-with-alexithymia-stress-and-social-support-among-romanian-medical-students-a-cross-sectional-study
#17
Ovidiu Popa-Velea, Liliana Diaconescu, Alexandra Mihăilescu, Mara Jidveian Popescu, George Macarie
Medical school students often experience emotional difficulties when handling the challenges of their formation, occasionally leading to burnout. In this study, we measured the prevalence of burnout and its relationships with perceived stress, perceived social support, and alexithymia in medical students from the largest academic medical community in Romania. A cross-sectional survey was administered to a randomized sample of 299 preclinical medical students at the University of Medicine in Bucharest. Participants completed four standardized questionnaires...
May 25, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28583985/preventing-newborn-deaths-in-romania-and-hungary
#18
EDITORIAL
Dorota Kuchna, Armine Hovsepyan, Sara Leonard
No abstract text is available yet for this article.
June 1, 2017: Health Affairs
https://www.readbyqxmd.com/read/28575931/recent-forest-cover-changes-2002-2015-in-the-southern-carpathians-a-case-study-of-the-iezer-mountains-romania
#19
Bogdan Mihai, Ionuț Săvulescu, Marina Rujoiu-Mare, Constantin Nistor
The paper explores the dynamics of the forest cover change in the Iezer Mountains, part of Southern Carpathians, in the context of the forest ownership recovery and deforestation processes, combined with the effects of biotic and abiotic disturbances. The aim of the study is to map and evaluate the typology and the spatial extension of changes in the montane forest cover between 700 and 2462m a.s.l., sampling all the representative Carpathian ecosystems, from the European beech zone up to the spruce-fir zone and the subalpine-alpine pastures...
December 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28560488/lived-religion-as-reproductive-decision-making-resource-among-romanian-women-who-use-abortion-as-contraception
#20
Cristina A Pop
This article draws upon qualitative ethnographic data collected between 2005 and 2013 in southern Romania among women who have been consistently using abortion as a contraceptive method. It particularly considers the role that lived religion might have played in some individuals' strategies to render abortion a justifiable practice. Over the last seven decades, Romanian women's experiences of abortion have often been at odds with both secular and religious regulations. This study shifts the perspective from the biopolitics and the bioethics of abortion toward women's own reproductive decision-making strategies in a context of enduring traditional patriarchy...
May 30, 2017: Journal of Religion and Health
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