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https://www.readbyqxmd.com/read/28437577/high-gene-flow-despite-opposite-chirality-in-hybrid-zones-between-enantiomorphic-door-snails
#1
Eva L Koch, Marco T Neiber, Frank Walther, Bernhard Hausdorf
We studied differentiation and gene flow patterns between enantiomorphic door-snail species in two hybrid zones in the Bucegi Mountains (Romania) to investigate the effects of intrinsic barriers (complications in copulation) and extrinsic selection by environmental factors. A mitochondrial gene tree confirmed the historical separation of the examined populations into the dextral Alopia livida and the sinistral Alopia straminicollis in accordance with the morphological classification, but also indicated gene flow between the species...
April 24, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28437183/first-two-imported-cases-of-zika-virus-infections-in-romania
#2
Simin Aysel Florescu, Ani Ioana Cotar, Corneliu Petru Popescu, Cornelia Svetlana Ceianu, Mihaela Zaharia, Geta Vancea, Daniel Codreanu, Daniela Badescu, Emanoil Ceausu
We report the first two cases of imported Zika virus (ZIKV) infection in Romanian patients returning from areas with ongoing outbreaks and challenges for laboratory diagnostic; first one with a classical pattern of acute flaviviral infection and the second one with an interesting pattern of a secondary flaviviral (ZIKV) infection in a yellow fever-vaccinated child living abroad in an endemic area.
February 23, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28436346/development-of-health-technology-assessment-in-romania
#3
Silvia Gabriela Scintee, Marius Ciutan
OBJECTIVES: The aim of this study was to describe and analyze the introduction of health technology (HTA) in Romania. METHODS: Based on a review of the literature and legislative documents and personal experiences and observations, the authors describe, evaluate, and explain the background and evolution of the HTA system. RESULTS: Initiatives to introduce HTA in Romania date from the early 1990s, but real steps were taken only in 2012 when the European Union Directive 2011/24/ on the application of patients' rights in cross-border health care had to be passed into Romanian law...
April 24, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28433111/epidemiology-and-introduction-to-the-clinical-presentation-of-wilson-disease
#4
Christine Lo, Oliver Bandmann
Our understanding of the epidemiology of Wilson disease has steadily grown since Sternlieb and Scheinberg's first prevalence estimate of 5 per million individuals in 1968. Increasingly sophisticated genetic techniques have led to revised genetic prevalence estimates of 142 per million. Various population isolates exist where the prevalence of Wilson disease is higher still, the highest being 885 per million from within the mountainous region of Rucar in Romania. In Sardinia, where the prevalence of Wilson disease has been calculated at 370 per million births, six mutations account for around 85% of Wilson disease chromosomes identified...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28410591/eurasian-golden-jackal-as-host-of-canine-vector-borne-protists
#5
Barbora Mitková, Kristýna Hrazdilová, Gianluca D'Amico, Georg Gerhard Duscher, Franz Suchentrunk, Pavel Forejtek, Călin Mircea Gherman, Ioana Adriana Matei, Angela Monica Ionică, Aikaterini Alexandra Daskalaki, Andrei Daniel Mihalca, Jan Votýpka, Pavel Hulva, David Modrý
BACKGROUND: Jackals are medium-sized canids from the wolf-like clade, exhibiting a unique combination of ancestral morphotypes, broad trophic niches, and close phylogenetic relationships with the wolf and dog. Thus, they represent a potential host of several pathogens with diverse transmission routes. Recently, populations of the Eurasian golden jackal Canis aureus have expanded into the Western Palaearctic, including most of Europe. The aim of our study was to examine Eurasian golden jackals from Romania, Czech Republic and Austria for a wide spectrum of vector-borne protists and to evaluate the role of this species as a reservoir of disease for domestic dogs and/or humans...
April 14, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28401006/genomic-and-proteomic-characterization-of-arid1a-chromatin-remodeller-in-ampullary-tumors
#6
Anca Nastase, Jin Yao Teo, Hong Lee Heng, Cedric Chuan Young Ng, Swe Swe Myint, Vikneswari Rajasegaran, Jia Liang Loh, Ser Yee Lee, London Lucien Ooi, Alexander Yaw Fui Chung, Pierce Kah Hoe Chow, Peng Chung Cheow, Wei Keat Wan, Rafy Azhar, Avery Khoo, Sam Xin Xiu, Syed Muhammad Fahmy Alkaff, Ioana Cutcutache, Jing Quan Lim, Choon Kiat Ong, Vlad Herlea, Simona Dima, Dan G Duda, Bin Tean Teh, Irinel Popescu, Tony Kiat Hon Lim
AT rich interactive domain 1A (ARID1A) is one of the most commonly mutated genes in a broad variety of tumors. The mechanisms that involve ARID1A in ampullary cancer progression remains elusive. Here, we evaluated the frequency of ARID1A and KRAS mutations in ampullary adenomas and adenocarcinomas and in duodenal adenocarcinomas from two cohorts of patients from Singapore and Romania, correlated with clinical and pathological tumor features, and assessed the functional role of ARID1A. In the ampullary adenocarcinomas, the frequency of KRAS and ARID1A mutations was 34...
2017: American Journal of Cancer Research
https://www.readbyqxmd.com/read/28399300/diversity-of-flea-siphonaptera-parasites-on-red-foxes-vulpes-vulpes-in-romania
#7
P Foley, J Foley, A D Sándor, A M Ionica, I A Matei, G D'Amico, C M Gherman, C Dom A, A D Mihalca
Red foxes (Vulpes vulpes (L.)) are widespread across Europe, tolerant of synanthropic ecosystems, and susceptible to diseases potentially shared with humans and other animals. We describe flea fauna on red foxes in Romania, a large, ecologically diverse country, in part because fleas may serve as an indicator of the risk of spillover of vector-borne disease. We found 912 individual fleas of seven species on the 305 foxes assessed, for an infestation prevalence of 49.5%. Mean flea load per fox was 5.8 (range 0-44 fleas), and flea detections were most abundant in fall and early spring...
March 25, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28393036/analysis-of-normal-human-retinal-vascular-network-architecture-using-multifractal-geometry
#8
Ştefan Ţălu, Sebastian Stach, Dan Mihai Călugăru, Carmen Alina Lupaşcu, Simona Delia Nicoară
AIM: To apply the multifractal analysis method as a quantitative approach to a comprehensive description of the microvascular network architecture of the normal human retina. METHODS: Fifty volunteers were enrolled in this study in the Ophthalmological Clinic of Cluj-Napoca, Romania, between January 2012 and January 2014. A set of 100 segmented and skeletonised human retinal images, corresponding to normal states of the retina were studied. An automatic unsupervised method for retinal vessel segmentation was applied before multifractal analysis...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28381960/characterization-of-pyrenophora-tritici-repentis-tan-spot-of-wheat-races-in-baltic-states-and-romania
#9
Sidrat Abdullah, Sunish Kumar Sehgal, Shaukat Ali, Zilvinas Liatukas, Mariana Ittu, Navjot Kaur
Tan spot, caused by the fungus Pyrenophora triticirepentis, is economically important foliar disease in Latvia, Lithuania, and Romania; however, race structure from Baltic States and Romania is not known. In this study, we performed genotypic and phenotypic race characterization of a large collection of P. triticirepentis isolates from these countries to determine race structure and utilize this information for better disease management and breeding wheat for tan spot resistance. We characterized 231 single spore isolates from Latvia (n = 15), Lithuania (n = 107), and Romania (n = 109) for Ptr ToxA and Ptr ToxB genes using two genes specific primers...
April 2017: Plant Pathology Journal
https://www.readbyqxmd.com/read/28381228/mesocarnivores-and-macroparasites-altitude-and-land-use-predict-the-ticks-occurring-on-red-foxes-vulpes-vulpes
#10
Attila D Sándor, Gianluca D'Amico, Călin M Gherman, Mirabela O Dumitrache, Cristian Domșa, Andrei Daniel Mihalca
BACKGROUND: The red fox Vulpes vulpes is the most common mesocarnivore in Europe and with a wide geographical distribution and a high density in most terrestrial habitats of the continent. It is fast urbanising species, which can harbor high numbers of different tick species, depending on the region. Here we present the results of a large-scale study, trying to disentangle the intricate relationship between environmental factors and the species composition of ectoparasites in red foxes...
April 5, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28379244/biofilm-composition-in-the-olt-river-romania-reservoirs-impacted-by-a-chlor-alkali-production-plant
#11
P Dranguet, C Cosio, S Le Faucheur, D Hug Peter, J-L Loizeau, V-Gh Ungureanu, V I Slaveykova
Freshwater biofilms can be useful indicators of water quality and offer the possibility to assess contaminant effects at the community level. The present field study examines the effects of chlor-alkali plant effluents on the community composition of biofilms grown in the Olt River (Romania) reservoirs. The relationship between ambient water quality variables and community composition alterations was explored. Amplicon sequencing revealed a significant modification of the composition of microalgal, bacterial and fungal communities in the biofilms collected in the impacted reservoirs in comparison with those living in the uncontaminated control reservoir...
April 5, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28378700/-carbapenem-resistant-bacteria-transferred-to-the-netherlands-patients-colonised-during-hospitalisation-in-romania
#12
M Hoogewerf, A E Budding, A M E Spoelstra-de Man, J Vloemans, W Rozemeijer
Three patients were recently transferred to two Intensive Care Units (ICUs) in the Netherlands from two different ICUs in Bucharest, Romania. The patients appeared to be colonised with several, partly identical, carbapenemase-producing bacteria (CPB) after a short hospitalisation in Romania. In this article, we show that it is important to be aware of the possibility that patients are colonised with CPB after a short hospitalisation abroad. This has consequences for infection prevention measurements, but probably also for the discontinuation of selective bowel decontamination in the ICU...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28363267/identification-and-prevalence-of-swine-pasivirus-1-in-eastern-romanian-pig-farms
#13
Mihaela Zaulet, Vlad Petrovan, Andrada M Birladeanu, Ana Maria M Stoian, Steliana E M Kevorkian, Cornelia Nichita, Marc Eloit, Laura Buburuzan
Swine pasivirus 1 (SPaV-1) was first detected in the feces of healthy pigs in France as a new species in family Picornaviridae. We investigated the presence, distribution, and genetic variability of this virus in 7 geographic areas with intensive pig breeding farms in eastern Romania. A total of 564 porcine specimens, including 82 fecal specimens and 482 pools of organs, were collected from healthy pigs in different stages of production from pathogen-free swine farming units. The virus was found in 6 of 7 areas investigated...
March 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28356815/a-higher-level-classification-of-the-pannonian-and-western-pontic-steppe-grasslands-central-and-eastern-europe
#14
Wolfgang Willner, Anna Kuzemko, Jürgen Dengler, Milan Chytrý, Norbert Bauer, Thomas Becker, Claudia Biţă-Nicolae, Zoltán Botta-Dukát, Andraž Čarni, János Csiky, Ruzica Igić, Zygmunt Kącki, Iryna Korotchenko, Matthias Kropf, Mirjana Krstivojević-Ćuk, Daniel Krstonošić, Tamás Rédei, Eszter Ruprecht, Luise Schratt-Ehrendorfer, Yuri Semenishchenkov, Zvjezdana Stančić, Yulia Vashenyak, Denys Vynokurov, Monika Janišová
QUESTIONS: What are the main floristic patterns in the Pannonian and western Pontic steppe grasslands? What are the diagnostic species of the major subdivisions of the class Festuco-Brometea (temperate Euro-Siberian dry and semi-dry grasslands)? LOCATION: Carpathian Basin (E Austria, SE Czech Republic, Slovakia, Hungary, Romania, Slovenia, N Croatia and N Serbia), Ukraine, S Poland and the Bryansk region of W Russia. METHODS: We applied a geographically stratified resampling to a large set of relevés containing at least one indicator species of steppe grasslands...
January 2017: Applied Vegetation Science
https://www.readbyqxmd.com/read/28347610/abundance-of-antibiotics-antibiotic-resistance-genes-and-bacterial-community-composition-in-wastewater-effluents-from-different-romanian-hospitals
#15
Edina Szekeres, Andreea Baricz, Cecilia Maria Chiriac, Anca Farkas, Ocsana Opris, Maria-Loredana Soran, Adrian-Stefan Andrei, Knut Rudi, Jose Luis Balcázar, Nicolae Dragos, Cristian Coman
Antimicrobial resistance represents a growing and significant public health threat, which requires a global response to develop effective strategies and mitigate the emergence and spread of this phenomenon in clinical and environmental settings. We investigated, therefore, the occurrence and abundance of several antibiotics and antibiotic resistance genes (ARGs), as well as bacterial community composition in wastewater effluents from different hospitals located in the Cluj County, Romania. Antibiotic concentrations ranged between 3...
March 24, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28347175/bioactive-capacity-of-some-romanian-wild-edible-mushrooms-consumed-mainly-by-local-communities
#16
Emanuel Vamanu
Wild edible mushrooms are considered as a cheap food source, but rich in bioactive compounds, especially in phenolic compounds. The purpose of the study was to determine the antioxidant and antimicrobial activity and the content of polyphenolcarboxylic acids in 10 species of mushrooms commonly used (consumed) in Romania and two controls. The effect against free radicals, lipid peroxidation and reducing power were determined. The antimicrobial effect was revealed on some strains with pathogenic effect by disk diffusion assay...
March 28, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28338110/frequency-of-the-ugt1a1-28-polymorphism-in-a-romanian-cohort-of-gilbert-syndrome-individuals
#17
Viorica E Radoi, Radu I Ursu, Elena Poenaru, Cosmin Arsene, Camil L Bohiltea, Roxana Bohiltea
BACKGROUND AND AIMS: Gilbert syndrome (GS) is characterized by unconjugated hyperbilirubinemia without liver disease or overt hemolysis and it is found in 3-10% of the general population. Inherited hyperbilirubinaemia is attributable to a reduced UGT1A1 activity. The UGT1A1 promoter (TA) repeats variants are documented of being involved in abnormally elevated bilirubin levels. The aim of the present study is to analyze the impact of UGT1A1 promoter variants on bilirubin levels in Romanian patients clinically supected with GS...
March 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/28336050/mortality-risk-disparities-in-children-receiving-chronic-renal-replacement-therapy-for-the-treatment-of-end-stage-renal-disease-across-europe-an-espn-era-edta-registry-analysis
#18
Nicholas C Chesnaye, Franz Schaefer, Marjolein Bonthuis, Rebecca Holman, Sergey Baiko, Esra Baskın, Anna Bjerre, Sylvie Cloarec, Elisabeth A M Cornelissen, Laura Espinosa, James Heaf, Rosário Stone, Diamant Shtiza, Ilona Zagozdzon, Jérôme Harambat, Kitty J Jager, Jaap W Groothoff, Karlijn J van Stralen
BACKGROUND: We explored the variation in country mortality rates in the paediatric population receiving renal replacement therapy across Europe, and estimated how much of this variation could be explained by patient-level and country-level factors. METHODS: In this registry analysis, we extracted patient data from the European Society for Paediatric Nephrology/European Renal Association-European Dialysis and Transplant Association (ESPN/ERA-EDTA) Registry for 32 European countries...
March 20, 2017: Lancet
https://www.readbyqxmd.com/read/28335825/canine-tick-borne-diseases-in-pet-dogs-from-romania
#19
Martin O Andersson, Conny Tolf, Paula Tamba, Mircea Stefanache, Jonas Waldenström, Gerhard Dobler, Lidia Chițimia-Dobler
BACKGROUND: Tick-borne diseases are of substantial concern worldwide for animals as well as humans. Dogs have been a human companion for millennia, and their significant impact on human life renders disease in dogs to be of great concern. Tick-borne diseases in dogs represent a substantial diagnostic challenge for veterinarians in that clinical signs are often diffuse and overlapping. In addition, co-infections with two or more pathogens enhance this problem further. Molecular methods are useful to disentangle co-infections and to accurately describe prevalence and geographical distribution of tick-borne diseases...
March 23, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28331840/consensus-statement-on-the-management-of-patients-with-hcv-infection-in-romania
#20
REVIEW
(no author information available yet)
BACKGROUND: HCV direct-acting antivirals (DAAs) have made treatment easier for both patients and healthcare practitioners, but have also brought new challenges in terms of patient management and monitoring prior to, during, and after treatment. METHODS: To sum up and unify the clinical experience of Romanian DAA prescribing physicians, we have organized a Consensus Meeting in November 2016 in Bucharest, Romania. CONSENSUS STATEMENT: The Consensus Meeting has provided expert answers to ten significant questions regarding HCV infection, namely: How do we diagnose patients with HCV infection? How do we stage liver disease in patients with HCV infection? How do we monitor patients with HCV infection prior to treatment? Which patients with HCV infection do we treat? When do we start treatment for HCV infection? What regimens do we use for treating HCV infection? How do we monitor patients with HCV infection during treatment? What adverse events should we expect during treatment of HCV infection and how do we prevent/manage them? How do we monitor patients with HCV infection after treatment? How do we expect the landscape of HCV to change in the following years? ...
March 2017: Germs
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