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Charlson's comorbidity-age index

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https://www.readbyqxmd.com/read/29052224/opiate-prescribing-in-hospitalized-older-adults-patterns-and-outcomes
#1
Sutapa Maiti, Liron Sinvani, Michele Pisano, Andrzej Kozikowski, Vidhi Patel, Meredith Akerman, Karishma Patel, Christopher Smilios, Christian Nouryan, Guang Qiu, Renee Pekmezaris, Gisele Wolf-Klein
BACKGROUND/OBJECTIVES: Whereas opiate prescribing patterns have been well described in outpatient and emergency department settings, they have been less defined in hospitalized older adults. The objective was to describe patterns of opiate prescribing and associated outcomes in hospitalized older adults. DESIGN: Retrospective cohort study. SETTING: Tertiary care facility. PARTICIPANTS: Hospitalized medical patients aged 65 and older (N = 9,245; mean age 80...
October 20, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29050679/glycaemic-control-of-elderly-patients-with-type-2-diabetes-mellitus-in-spain-2015-and-its-relationship-with-functional-capacity-and-comorbidity-the-escadiane-study
#2
F J Sangrós-González, J Martínez-Candela, L Avila-Lachica, J Díez-Espino, J M Millaruelo-Trillo, J García-Soidán, L Carrillo Fernández, P Ezkurra Loiola
OBJECTIVES: To understand the state of glycaemic control of elderly patients with type 2 diabetes mellitus in Spain and its relationship with functional capacity and comorbidity. METHODS: Cross-sectional, observational, multicentre national study on patients with diabetes mellitus aged 65 years or older. The study analysed demographic and anthropometric variables, cardiovascular risk factors, clinical and laboratory data, associated comorbidity and treatments. We analysed the functional capacity using the Barthel index and the comorbidity with Charlson index...
October 16, 2017: Revista Clínica Española
https://www.readbyqxmd.com/read/29044930/effect-of-incident-nocturnal-home-hemodialysis-versus-incident-continuous-ambulatory-peritoneal-dialysis-on-employment-rate-clinical-and-laboratory-outcomes-a-1-year-retrospective-observation-study
#3
John Wing Li, Joseph Ho Sing Wong, Wai Leung Chak, Ka Foon Chau
INTRODUCTION: While studies demonstrated favorable outcomes of nocturnal home hemodialysis (NHHD), direct comparison on employment rate, clinical and laboratory outcomes between the NHHD and continuous ambulatory peritoneal dialysis (CAPD) had not been previously performed. METHODS: A 1-year retrospective observation study was performed in 20 incidents alternate night NHHD and 81 incident CAPD patients of Chinese ethnicity, who were sex, diabetic status, and Charlson comorbidity index matched, but not age due to our center's age limit for NHHD enrollment...
October 18, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/29034615/effects-of-an-exercise-model-based-on-functional-circuits-in-an-older-population-with-different-levels-of-social-participation
#4
Walter Sepúlveda Loyola, Carlos Augusto Camillo, Carolina Valenzuela Torres, Vanessa Suziane Probst
AIM: To investigate whether being part of a community organization interfered with older adults' overall functionality. The magnitude of responses to a community exercise program based on functional circuits in socially active and socially non-active older adults was also investigated. METHODS: A total of 200 older adults aged ≥60 years from Requinoa, Chile, participated in the study. Participants were separated into two groups according to the level of social participation: socially active (SA) and socially non-active (SNA)...
October 15, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29030143/impact-of-atrial-fibrillation-on-outcomes-with-motor-vehicle-accidents
#5
Kanishk Agnihotri, N V Pothineni, Paris Charilaou, Vaibhav R Vaidya, Badal Thakkar, Vishal Goyal, Sabeeda Kadavath, Nileshkumar Patel, Apurva Badheka, Peter Noseworthy, Suraj Kapa, Paul Friedman, Bernard Gersh, Hakan Paydak, Abhishek Deshmukh
BACKGROUND: We examined the effect of AF a commonly encountered arrhythmia with significant morbidity on mortality following a motor vehicle accident (MVA) related hospitalization. METHODS: The Nationwide Inpatient Sample (NIS) was queried to identify patients with AF (ICD-9 CM 427.31) and MVA (ICD-9 CM E810.0-E819.9), considered separately and together, from 2003 through 2012. Baseline characteristics were identified and multilevel mixed model multivariate analysis was employed to verify the impact of AF on in-patient mortality in survivors...
October 3, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29029001/comparative-study-of-bicuspid-vs-tricuspid-aortic-valve-stenosis
#6
Geoffrey D Huntley, Jeremy J Thaden, Said Alsidawi, Hector I Michelena, Joseph J Maleszewski, William D Edwards, Christopher G Scott, Sorin V Pislaru, Patricia A Pellikka, Kevin L Greason, Naser M Ammash, Joseph F Malouf, Maurice Enriquez-Sarano, Vuyisile T Nkomo
Aims: To examine differences and similarities in bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV) stenosis occurring during the same age and whether any differences impact outcomes following aortic valve replacement (AVR). Methods and results: An age-matched cohort of 198 BAV stenosis and 198 TAV stenosis patients was identified from 888 consecutive patients undergoing AVR for severe AS. Mean age 68 ± 6 years; 68% male. Patients with BAV were less likely to have multiple comorbidities, as measured by the Charlson Comorbidity Index (CCI) >2 (3 vs...
October 3, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29027888/same-hospital-re-admission-rate-is-not-reliable-for-measuring-post-operative-infection-related-re-admission
#7
Rishi Rattan, Joshua Parreco, Tanya L Zakrison, D Dante Yeh, Howard M Lieberman, Nicholas Namias
BACKGROUND: Post-operative infections cause morbidity, consume resources, and are an important quality measure in assessing and comparing hospitals. Commonly used metrics do not account for re-admission to a different hospital. The Nationwide Readmissions Database (NRD) tracks re-admissions across United States (US) hospitals. Infection-related re-admission across US hospitals has not been studied previously. PATIENTS AND METHODS: The 2013 NRD was queried for admissions with a primary International Classification of Diseases and Related Health Problems, 9th revision, Clinical Modification code for the most frequently performed operations...
October 13, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29025270/design-of-a-randomized-clinical-trial-of-a-colorectal-cancer-screening-decision-aid-to-promote-appropriate-screening-in-community-dwelling-older-adults
#8
Christine E Kistler, Carol Golin, Carolyn Morris, Alexandra F Dalton, Russell P Harris, Rowena Dolor, Renée M Ferrari, Noel T Brewer, Carmen L Lewis
BACKGROUND: Appropriate colorectal cancer screening in older adults should be aligned with the likelihood of net benefit. In general, patient decision aids improve knowledge and values clarity, but in older adults, they may also help patients identify their individual likelihood of benefit and foster individualized decision-making. We report on the design of a randomized clinical trial to understand the effects of a patient decision aid on appropriate colorectal cancer screening. This report includes a description of the baseline characteristics of participants...
August 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/29024046/traumatic-brain-injury-in-the-prodromal-period-of-parkinson-disease-a-large-epidemiological-study-using-medicare-data
#9
Alejandra Camacho-Soto, Mark N Warden, Susan Searles Nielsen, Amber Salter, David L Brody, Heidi Prather, Brad A Racette
OBJECTIVE: Studies suggest a greater risk of Parkinson disease (PD) after traumatic brain injury (TBI), but it is possible that the risk of TBI is greater in the prodromal period of PD. We aimed to examine the time-to-TBI in PD patients in their prodromal period compared to population-based controls. METHODS: We identified 89,790 incident PD cases and 118,095 comparable controls > 65 years of age in 2009 using Medicare claims data. Using data from the preceding five years, we compared time-to-TBI in PD patients in their prodromal period to controls...
October 10, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29021355/population-based-study-of-home-time-by-stroke-type-and-correlation-with-modified-rankin-score
#10
Amy Y X Yu, Edwin Rogers, Meng Wang, Tolulope T Sajobi, Shelagh B Coutts, Bijoy K Menon, Michael D Hill, Eric E Smith
OBJECTIVE: To describe home-time, stratified by stroke type, in a complete population and to determine its correlation with modified Rankin Scale (mRS) scores. METHODS: We used linked administrative data to derive home-time in all patients admitted for a cerebrovascular event in Alberta, Canada, between 2012 and 2016. Home-time is the number of days spent outside a health institution in the first 90 days after index hospitalization. We used negative binomial regression, adjusted for age, sex, Charlson comorbidity index, and hospital location, to determine the association between home-time and stroke type...
October 11, 2017: Neurology
https://www.readbyqxmd.com/read/29017106/surgical-outcomes-after-laminoplasty-for-cervical-spondylotic-myelopathy-a-focus-on-the-dynamic-factors-and-signal-intensity-changes-in-the-intramedullary-spinal-cord-on-mri
#11
Masashi Miyazaki, Naoki Notani, Toshinobu Ishihara, Shozo Kanezaki, Hiroshi Tsumura
OBJECTIVE: We aimed to analyze the relationship between the dynamic factors and signal intensity changes in the intramedullary spinal cord on MRI, and surgical outcomes, following double-door laminoplasty for cervical spondylotic myelopathy (CSM). PATIENTS AND METHODS: This retrospective study included 100 consecutive patients who underwent double-door laminoplasty for CSM. The following factors were analyzed: JOA score recovery rate, age, duration from onset to surgery, intraoperative bleeding, signal intensity changes in the intramedullary spinal cord on MRI, pre and postoperative C2-7 lordotic angle (LA), changes in C2-7 LA, pre and postoperative C2-7 range of motion (ROM), and pre and postoperative segmental ROM...
October 4, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28991949/post-intensive-care-unit-psychiatric-comorbidity-and-quality-of-life
#12
Sophia Wang, Chris Mosher, Anthony J Perkins, Sujuan Gao, Sue Lasiter, Sikandar Khan, Malaz Boustani, Babar Khan
The prevalence of psychiatric symptoms ranges from 17% to 44% in intensive care unit (ICU) survivors. The relationship between the comorbidity of psychiatric symptoms and quality of life (QoL) in ICU survivors has not been carefully examined. This study examined the relationship between psychiatric comorbidities and QoL in 58 survivors of ICU delirium. Patients completed 3 psychiatric screens at 3 months after discharge from the hospital, including the Patient Health Questionnaire-9 (PHQ-9) for depression, the Generalized Anxiety Disorder-7 (GAD-7) questionnaire for anxiety, and the Post-Traumatic Stress Syndrome (PTSS- 10) questionnaire for posttraumatic stress disorder...
October 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28991499/outcome-of-traumatic-brain-injury-in-patients-on-antiplatelet-agents-a-retrospective-20-year-observational-study-in-a-single-neurosurgery-unit
#13
Kyoko Sumiyoshi, Takanori Hayakawa, Hiroshi Yatsushige, Keigo Shigeta, Toshiya Momose, Masaya Enomoto, Shin Sato, Yoshio Takasato
OBJECTIVE: To evaluate the outcomes after Traumatic Brain Injury (TBI) in patients taking Antiplatelet Agents (APAs). METHODS: We reviewed the clinical records of 934 patients with TBI between 1995 and 2014. Multivariate analysis was performed to correlate patient outcome with various factors, including pre-injury APA intake. Cause of death was compared among groups stratified according to APA dose. RESULTS: Increasing doses of APAs were positively associated with mortality rates, however, differences were primarily due to non-traumatic causes...
October 9, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28987469/prevalence-of-sarcopenia-and-its-association-with-activities-of-daily-living-and-dysphagia-in-convalescent-rehabilitation-ward-inpatients
#14
Yoshihiro Yoshimura, Hidetaka Wakabayashi, Takahiro Bise, Maiko Tanoue
BACKGROUND: The purpose of this study was to investigate the prevalence of sarcopenia following stroke, musculoskeletal disease, or hospital-associated deconditioning in convalescent rehabilitation ward inpatients. The association between the activities of daily living (ADLs), dysphagia, and sarcopenia was also assessed. METHODS: A cross-sectional study was performed in consecutive patients admitted to convalescent rehabilitation wards. Sarcopenia was defined as a loss of skeletal muscle mass and decreased muscle strength...
September 23, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28982749/a-population-based-assessment-of-emergency-department-observation-status-for-older-adults-with-cancer
#15
Allison Lipitz-Snyderman, Adam Klotz, Renee L Gennarelli, Jeffrey Groeger
Background: Hospitals' use of observation status for patients with cancer presenting to the emergency department (ED) is not well understood. This model of care delivery may be a viable alternative to inpatient admission for patients with cancer presenting with certain conditions. Our objective was to assess the use of observation status among Medicare beneficiaries with and without cancer. Methods: Population-based SEER-Medicare data were used to assess differences in the use of observation status between Medicare beneficiaries aged ≥66 years with and without cancer using a matched analysis (n=151,183 per cohort)...
October 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28977049/causes-and-predictors-of-in-hospital-mortality-in-patients-admitted-with-or-for-heart-failure-at-a-tertiary-hospital-in-brazil
#16
André Wajner, Priccila Zuchinali, Vírgilio Olsen, Carisi A Polanczyk, Luis Eduardo Rohde
BACKGROUND: Although heart failure (HF) has high morbidity and mortality, studies in Latin America on causes and predictors of in-hospital mortality are scarce. We also do not know the evolution of patients with compensated HF hospitalized for other reasons. OBJECTIVE: To identify causes and predictors of in-hospital mortality in patients hospitalized for acute decompensated HF (ADHF), compared to those with HF and admitted to the hospital for non-HF related causes (NDHF)...
September 28, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28976022/development-and-validation-of-prognostic-survival-models-in-newly-diagnosed-parkinson-s-disease
#17
Angus D Macleod, Ingvild Dalen, Ole-Bjørn Tysnes, Jan Petter Larsen, Carl E Counsell
OBJECTIVE: The objective of this study was to develop valid prognostic models to predict mortality, dependency, and "death or dependency" for use in newly diagnosed Parkinson's disease (PD). METHODS: The models were developed in the Parkinsonism Incidence in North-East Scotland study (UK, 198 patients) and validated in the ParkWest study (Norway, 192 patients), cohorts that attempted to identify and follow-up all new PD cases in the study area. Dependency was defined using the Schwab & England scale...
October 4, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28974909/age-adjusted-charlson-comorbidity-index-scores-predict-major-adverse-cardiovascular-events-and-all-cause-mortality-among-systemic-lupus-erythematosus-patients
#18
Mei-Hua Chuang, Tzyy-Ling Chuang, Kuang-Yung Huang, Yuh-Feng Wang
OBJECTIVE: Cardiovascular events are the most frequent cause of death or disability among people with systemic lupus erythematosus (SLE). However, the causes of this increased the risk of major adverse cardiovascular events (MACEs) are not completely understood. The Age-adjusted Charlson Comorbidity Index (ACCI) is a prognostic classification that was initially developed for patients who have a number of comorbid conditions and the ACCI has been validated in many clinical settings. MATERIALS AND METHODS: In this study, 5998 patients were enrolled from the National Health Research Institute Database of Taiwan...
July 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28974464/association-between-caregiver-role-and-short-and-long-term-functional-recovery-after-hip-fracture-a-prospective-study
#19
Marlis Nardi, Karina Fischer, Bess Dawson-Hughes, Endel J Orav, Otto W Meyer, Ursina Meyer, Sacha Beck, Hans-Peter Simmen, Hans-Christoph Pape, Andreas Egli, Walter C Willett, Robert Theiler, Heike A Bischoff-Ferrari
OBJECTIVES: After a hip fracture, 50% of senior patients are left with permanent functional decline and 30% lose their autonomy. The aim of this prospective study was to evaluate whether seniors who are in a caregiver role have better functional recovery after hip fracture compared with noncaregivers. DESIGN: Prospective observational study. SETTING: A total of 107 Swiss patients with acute hip fracture age 65 years and older (84% women; 83...
September 30, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28971790/sepsis-after-elective-ureteroscopy
#20
Jonathan Bloom, Cristina Fox, Sean Fullerton, Gerald Matthews, John Phillips
INTRODUCTION: We sought to determine our rate of postoperative sepsis after ureteroscopy as well as identifying associative factors, common antibiotic practices along with culture data. MATERIALS AND METHODS: Records of all patients who underwent elective ureteroscopy from 2010 to 2015 at an urban tertiary care facility were retrospectively reviewed. Factors thought to be associated with infection were collected, along with comorbidities depicted as Charlson Age-Adjusted Comorbidity Index (CAACI) and American Society of Anesthesia (ASA) score...
October 2017: Canadian Journal of Urology
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