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https://www.readbyqxmd.com/read/29674111/pre-operative-factors-associated-with-increased-mortality-in-elderly-patients-with-a-hip-fracture-a-cohort-study-in-a-developing-country
#1
Kristian A Espinosa, Amparo Gómez Gélvez, Liliana P Torres, María Fernanda García, Omar R Peña
BACKGROUND: Hip fractures are a public health problem worldwide, and several factors are involved with post-operative mortality. The aim of this study was to identify the pre-operative factors associated with increased mortality in elderly patients with hip fractures in a developing country during the first post-operative year. METHODS: An ambidirectional cohort study was conducted with patients ≥ 65 years of age who underwent hip surgery due to a hip fracture caused by a fall from a standing position...
April 13, 2018: Injury
https://www.readbyqxmd.com/read/29672879/increased-left-atrial-size-is-associated-with-higher-atrial-fibrillation-recurrence-in-patients-treated-with-anti-arrhythmic-medications
#2
Saarang Mulukutla, Andrew D Althouse, Sandeep K Jain, Samir Saba
BACKGROUND: Atrial fibrillation (AF) is highly prevalent and antiarrhythmic therapy is often used to help with rhythm control. Some common echocardiographic parameters may be useful in predicting AF recurrence among these patients. OBJECTIVES: The purpose of this study was to evaluate the association between three common echocardiographic parameters [left atrial (LA) size, left ventricular ejection fraction (LVEF), and mitral regurgitation (MR)] and AF recurrence among patients treated with anti-arrhythmic medications...
April 19, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29671284/comparative-cardiovascular-risks-of-dipeptidyl-peptidase-4-inhibitors-analyses-of-real-world-data-in-korea
#3
Kyoung Hwa Ha, Bongseong Kim, Hae Sol Shin, Jinhee Lee, Hansol Choi, Hyeon Chang Kim, Dae Jung Kim
BACKGROUND AND OBJECTIVES: To compare cardiovascular disease (CVD) risk associated with 5 different dipeptidyl peptidase-4 inhibitors (DPP-4is) in people with type 2 diabetes. METHODS: We identified 534,327 people who were newly prescribed sitagliptin (n=167,157), vildagliptin (n=67,412), saxagliptin (n=29,479), linagliptin (n=220,672), or gemigliptin (n=49,607) between January 2013 and June 2015 using the claims database of the Korean National Health Insurance System...
February 27, 2018: Korean Circulation Journal
https://www.readbyqxmd.com/read/29671066/hartmann-s-reversal-after-colonic-perforation-or-anastomosis-leakage-is-it-the-same-procedure-a-retrospective-study-of-150-patients
#4
Nathalie Chereau, Jeremie H Lefevre, Najim Chafai, Thevy Hor, Clotilde Debove, Emmanuel Tiret, Yann Parc
PURPOSE: The high morbidity rates reported might influence surgeons' decisions of whether to perform Hartmann's reversal (HR). Our aim was to report the results of HR after "primary" Hartmann's procedure (HP) or in redo surgery for failed anastomosis. METHODS: All patients operated between 2007 and 2015 were included. Data and postoperative course were obtained from a review of medical records and databases. RESULTS: One hundred fifty patients (age 60, range (20-91) years, 62% male) were included...
April 18, 2018: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29669670/utilization-and-timeliness-of-an-inpatient-penicillin-allergy-evaluation
#5
Keith A Sacco, Razvan Chirila, Claudia Libertin, Brett Hiroto, Arveen Bhasin, Margaret M Johnson, Thanai Pongdee, M Caroline Burton
BACKGROUND: A history of penicillin allergy is associated with an increased risk of nosocomial infections because patients are exposed to non-beta lactam antibiotics. Ruling out inaccurate penicillin allergy during hospitalization decreases prescription of beta lactam antibiotics. However, the utilization of penicillin allergy testing and timeliness in relation to initiation of antibiotics is not known. OBJECTIVE: Our aim was to describe the proportion and characteristics of patients who underwent inpatient penicillin allergy testing in a hospital without a guideline or infrastructure for inpatient penicillin allergy testing...
May 1, 2018: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/29669572/one-year-and-three-year-mortality-prediction-in-adult-major-blunt-trauma-survivors-a-national-retrospective-cohort-analysis
#6
Ting Hway Wong, Nivedita Vikas Nadkarni, Hai V Nguyen, Gek Hsiang Lim, David Bruce Matchar, Dennis Chuen Chai Seow, Nicolas K K King, Marcus Eng Hock Ong
BACKGROUND: Survivors of trauma are at increased risk of dying after discharge. Studies have found that age, head injury, injury severity, falls and co-morbidities predict long-term mortality. The objective of our study was to build a nomogram predictor of 1-year and 3-year mortality for major blunt trauma adult survivors of the index hospitalization. METHODS: Using data from the Singapore National Trauma Registry, 2011-2013, we analyzed adults aged 18 and over, admitted after blunt injury, with an injury severity score (ISS) of 12 or more, who survived the index hospitalization, linked to death registry data...
April 18, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/29664343/peripheral-arterial-disease-changes-in-clinical-outcomes-and-therapeutic-strategies-in-two-cohorts-from-2002-to-2008-and-from-2008-to-2014-a-population-based-study
#7
Marta Baviera, Vittorio Bertelè, Fausto Avanzini, Tommaso Vannini, Mauro Tettamanti, Ida Fortino, Angela Bortolotti, Luca Merlino, Maria Carla Roncaglioni
Background The aim of our study was to evaluate whether treatments for peripheral artery disease changed in two different cohorts identified in 2002 and 2008, and whether this had an impact on mortality and major clinical outcomes after six years of follow-up. Methods Using administrative health databases of the largest region in Northern Italy, we identified patients admitted to hospital for peripheral artery disease in 2002 and 2008. Both cohorts were followed for six years. All cause death, acute coronary syndrome, stroke and major amputations, cardiovascular prevention drugs and revascularization procedures were collected...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29660105/the-impact-of-non-persistence-on-the-direct-and-indirect-costs-in-patients-treated-with-subcutaneous-tumour-necrosis-factor-alpha-inhibitors-in-germany
#8
Kathrin Ziegelbauer, Karel Kostev, Maximilian Hübinger, Silvia Dombrowski, Michael Friedrichs, Heiko Friedel, Sumesh Kachroo
Objective: The goal of the present study was to estimate the treatment costs in immune-mediated rheumatic disease patients initiating treatment with an s.c. biologic agent based on treatment persistence. Methods: This is a retrospective cohort study based on the German statutory health insurance funds database. Patients ⩾18 years of age with a diagnosis of AS, PsA or RA treated with s.c. TNF-α inhibitors (TNFis) were included. Persistence was estimated as the duration of time from s...
April 12, 2018: Rheumatology
https://www.readbyqxmd.com/read/29659630/body-mass-index-of-92-027-patients-acutely-admitted-to-general-hospitals-in-denmark-associated-clinical-characteristics-and-30-day-mortality
#9
Sigrid Bjerge Gribsholt, Lars Pedersen, Bjørn Richelsen, Olaf Dekkers, Reimar Wernich Thomsen
BACKGROUND: Data are sparse on the range of BMI among patients acutely admitted to general hospitals. We investigated BMI values and associated patient characteristics, reasons for hospital admission, and mortality in Denmark. METHODS: We identified all persons with an acute inpatient admission 2011-2014 in Central Denmark Region and assessed BMI measurements recorded in the Clinical Information System. We used cross-sectional and cohort analyses to examine the BMI distribution and its association with demographic characteristics, comorbidities, medication use, tobacco smoking, reasons for admission, and 30-day mortality...
2018: PloS One
https://www.readbyqxmd.com/read/29659593/the-complexity-of-patients-hospitalized-in-internal-medicine-wards-evaluated-by-fadoi-complimed-score-s-a-hypothetical-approach
#10
Erminio Bonizzoni, Gualberto Gussoni, Giancarlo Agnelli, Raffaele Antonelli Incalzi, Moira Bonfanti, Franco Mastroianni, Marco Candela, Carlotta Franchi, Stefania Frasson, Antonio Greco, Micaela La Regina, Roberta Re, Giorgio Vescovo, Mauro Campanini
OBJECTIVES: The aim of this study is to develop a new predictive model to measure complexity of patients in medical wards. SETTING: 29 Internal Medicine departments in Italy. MATERIALS AND METHODS: The study cohort was made of 541 consecutive patients hospitalized for any cause, aged more than 40 years and with at least two chronic diseases. First, we applied a hierarchical cluster analysis and the principal component analysis (PCA) to a panel of questionnaires [comorbidity (Charlson, CIRS), clinical stability (MEWS), social frailty (Flugelman), cognitive dysfunction (SPSMQ), depression (5-item GDS), functional dependence (ADL, IADL, Barthel), risk of sore threats (Exton-Smith scale), nutrition (MNA), pain (NRPS), adherence to therapy (Morisky scale)], in order to select domains informative for the definition of complexity...
2018: PloS One
https://www.readbyqxmd.com/read/29658980/relative-complications-and-trends-of-outpatient-total-shoulder-arthroplasty
#11
Armin Arshi, Natalie L Leong, Christopher Wang, Zorica Buser, Jeffrey C Wang, Peter S Vezeridis, David R McAllister, Frank A Petrigliano
Outpatient arthroplasty is an appealing option among select patient populations as a mechanism for reducing health care expenditure. The purpose of this study was to determine the nationwide trends and complication profile of outpatient total shoulder arthroplasty (TSA). The authors reviewed a national administrative claims database to identify patients undergoing TSA as outpatients and inpatients from 2007 to 2016. The incidence of perioperative surgical and medical complications was determined by querying for relevant International Classification of Diseases, Ninth Revision, and Current Procedural Terminology codes...
April 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29656727/outcomes-in-hospitalized-ischemic-stroke-patients-with-dementia-on-admission-a-population-based-cohort-study
#12
Charlotte Zerna, Mary P Lindsay, Jiming Fang, Richard H Swartz, Eric E Smith
BACKGROUND: Dementia prevalence is rising, and it will double in the next 20 years. This study sought to understand the prevalence of dementia in hospitalized patients with ischemic stroke, and its impact on outcomes. METHODS: Using the Canadian Institute of Health Information's (CIHI) Discharge Abstract Database (DAD), all acute ischemic stroke admissions from April 2003 to March 2015 in Canada (excluding Quebec) were analyzed. Concurrent dementia at the time of admission was assessed based on hospital diagnostic codes...
April 16, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29650416/effect-of-comorbidities-in-stage-ii-iii-colorectal-cancer-patients-treated-with-surgery-and-neoadjuvant-adjuvant-chemotherapy-a-single-center-observational-study
#13
Marina Baretti, Lorenza Rimassa, Nicola Personeni, Laura Giordano, Maria Chiara Tronconi, Tiziana Pressiani, Silvia Bozzarelli, Armando Santoro
BACKGROUND: Comorbidity has a detrimental effect on cancer survival, however, it is difficult to disentangle its direct effect from its influence on treatment choice. In this study we assessed the effect of comorbidity on survival in patients who received standard treatment for resected stage II and III colorectal cancer (CRC). PATIENTS AND METHODS: In total, 230 CRC patients, 68 rectal (29.6%) and 162 colon cancer (70.4%) treated with surgical resection and neoadjuvant/adjuvant chemotherapy from December 2002 to December 2009 at Humanitas Cancer Center were retrospectively reviewed...
March 21, 2018: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/29650403/is-age-a-risk-factor-for-depression-among-the-oldest-old-with-cancer
#14
Gil Goldzweig, Lea Baider, Yakir Rottenberg, Elisabeth Andritsch, Jeremy M Jacobs
INTRODUCTION: Age is negatively related to depression among young and middle age patients with cancer. Nevertheless the relationship between age and depression among older patients with cancer is unclear. The goal of the current study is to assess the association of depression with increasing age among older patients with cancer. MATERIALS AND METHODS: Participants were 243 oncology out-patients, aged ≥65, either receiving treatment for active disease or within 6 months of completing treatment for active disease, with a Karnofsky score ≥70...
April 9, 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29649609/surgical-treatment-improves-survival-of-elderly-with-axis-fracture-a-national-population-based-multi-registry-cohort-study
#15
Anna-Lena Robinson, Claes Olerud, Yohan Robinson
Background Context Fractures of the axis (C2) are the most common cervical spinal injuries in the elderly population. Several authors have reported improved survival among elderly patients with C2 fractures when treated surgically. Purpose To analyze whether surgery improves survival of elderly with C2 fractures. Study Design/ Setting Observational population-based longitudinal multi-registry study Patient Sample Swedish Patient Registry 1997 to 2014, and Swedish Cause of Death Registry 1997 to 2014 Outcome measures Survival after C2 fracture according to non-surgical and surgical treatment...
April 9, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29627936/invasive-fungal-infections-associated-with-prior-respiratory-viral-infections-in-immunocompromised-hosts
#16
Saira Ajmal, Maryam Mahmood, Omar Abu Saleh, Jenifer Larson, M Rizwan Sohail
BACKGROUND: Increased risk of invasive pulmonary aspergillosis after influenza infection has been reported; however data are limited. PURPOSE: To describe Invasive fungal infections (IFI) associated with preceding respiratory viral infection at a large referral center. METHODS: We reviewed all IFI cases among patients with positive influenza and/or RSV nasopharyngeal/lower respiratory tract PCR from October 2015 to December 2016. Cases of pulmonary IFI were classified as possible, probable, and definite based on EORTC-MSG definitions...
April 7, 2018: Infection
https://www.readbyqxmd.com/read/29626655/complications-and-cost-of-single-stage-vs-two-stage-bilateral-unicompartmental-knee-arthroplasty-a-case-control-study
#17
C Siedlecki, P Beaufils, B Lemaire, N Pujol
BACKGROUND: Single-stage bilateral knee arthroplasty, even when unicompartmental, remains controversial, chiefly due to the risk of peri-operative complications. The primary objective of this study was to compare the short-term complication rate and cost of single- vs. two-stage bilateral unicompartmental knee arthroplasty (UCA). The secondary objective was to compare total hospital stay lengths and motion-range recovery. HYPOTHESIS: Single-stage bilateral UCA is a cost-saving alternative that is not associated with higher complication rates compared to two-stage bilateral UCA...
April 4, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29624974/cost-of-hospitalizations-for-older-adults-at-one-imss-regional-general-hospital
#18
Víctor Granados-García, Sergio Sánchez-García, Ricardo Ramírez-Aldana, Carmen Zúñiga-Trejo, María Claudia Espinel-Bermúdez
Background: Population aging has a direct impact on the increasing demand of health services and on medical care costs. The objective was to carry out a cost analysis of health care costs in older adults in a regional general hospital of the Instituto Mexicano del Seguro Social. Methods: A calculation of the costs was done based on a retrospective collection of health care data. Unit prices were used to estimate costs. These were reported in 2016 Mexican pesos. A cost analysis was carried out by means of a regression model...
2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29624633/disparities-in-the-survivorship-experience-among-latina-survivors-of-breast-cancer
#19
Tinuke O Olagunju, Yihang Liu, Li-Jung Liang, James M Stomber, Jennifer J Griggs, Patricia A Ganz, Amardeep Thind, Rose C Maly
BACKGROUND: The authors investigated disparities in the survivorship experience among Latinas with breast cancer (BC) in comparison with non-Latinas. METHODS: A cross-sectional bilingual telephone survey was conducted among 212 Latina and non-Latina women within 10 to 24 months after a diagnosis of BC (AJCC TNM staging system stage 0-III) at 2 Los Angeles County public hospitals. Data were collected using the Preparing for Life as a (New) Survivor (PLANS) scale, Perceived Efficacy in Patient-Physician Interactions Questionnaire (PEPPI), Breast Cancer Prevention Trial (BCPT) Symptom Checklist, Satisfaction with Care and Information Scale, Consumer Assessment of Healthcare Providers and Systems (CAHPS) tool, Charlson Comorbidity Index adapted for patient self-report, and the 12-item Short Form Health Survey...
April 6, 2018: Cancer
https://www.readbyqxmd.com/read/29624099/use-of-electronic-health-records-to-characterize-a-rare-disease-in-the-usa-treatment-comorbidities-and-follow-up-trends-among-patients-with-a-confirmed-diagnosis-of-acromegaly
#20
Julie M Silverstein, Erin D Roe, Kashif M Munir, Janet L Fox, Birol Emir, Maria Kouznetsova, Lois E Lamerato, Donna King
Purpose Understanding of acromegaly disease management is hampered in the US by lack of a national registry. We describe medical management in a population with confirmed acromegaly. Methods Inpatient and outpatient Electronic Health Records (EHR) were used to create a database of de-identified patients assigned the Acromegaly and Gigantism ICD-9 code and/or an appropriate pituitary procedure code at one of four regional hospital systems over a 6-11 year period. Information regarding demographics, medical history, labs, procedures and medications was collected and supplemented with a chart review to validate the diagnosis of acromegaly...
April 6, 2018: Endocrine Practice
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