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https://www.readbyqxmd.com/read/28524027/-effect-of-chest-physiotherapy-in-patients-undergoing-mechanical-ventilation-a-prospective-randomized-controlled-trial
#1
Hui Zeng, Zhen Zhang, Yuan Gong, Miao Chen
OBJECTIVE: To investigate the effect of chest physiotherapy (CPT) on patients undergoing mechanical ventilation (MV). METHODS: A prospective randomized controlled trial (RCT) was conducted. Sixty-eight adult patients undergoing invasive MV over 48 hours admitted to intensive care unit (ICU) of Affiliated Hospital of Zunyi Medical College from December 2014 to October 2016 were enrolled, and they were divided into CPT group (n = 37) and control group (n = 31) by random number table...
May 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28487415/randomized-comparison-of-helmet-cpap-versus-high-flow-nasal-cannula-oxygen-in-pediatric-respiratory-distress
#2
Giovanna Vitaliti, Maria Concetta Vitaliti, Maria Carla Finocchiaro, Vita Antonella Di Stefano, Piero Pavone, Nassim Matin, Nazgol Motamed-Gorji, Riccardo Lubrano, Raffaele Falsaperla
BACKGROUND: The current study aimed to compare the efficacy and safety of 2 noninvasive respiratory support methods, which included helmet CPAP and high-flow nasal cannula (HFNC) in children with respiratory distress admitted to a pediatric intermediate care unit. METHODS: This study was a prospective observational study conducted on children with respiratory distress (age 1-24 months) who were admitted to our acute and emergency operative unit. All included subjects were randomly treated with helmet CPAP or HFNC in a 1:1 fashion until their clinical picture, oxygen saturation, and arterial blood gas (ABG) parameters resolved...
May 9, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28445859/a-risk-scoring-model-based-on-vital-signs-and-laboratory-data-predicting-transfer-to-the-intensive-care-unit-of-patients-admitted-to-gastroenterology-wards
#3
Won-Young Kim, Jinmi Lee, Ju-Ry Lee, Youn Kyung Jung, Hwa Jung Kim, Jin Won Huh, Chae-Man Lim, Younsuck Koh, Sang-Bum Hong
PURPOSE: To compare the ability of a score based on vital signs and laboratory data with that of the modified early warning score (MEWS) to predict ICU transfer of patients with gastrointestinal disorders. MATERIALS AND METHODS: Consecutive events triggering medical emergency team activation in adult patients admitted to the gastroenterology wards of the Asan Medical Center were reviewed. Binary logistic regression was used to identify factors predicting transfer to the ICU...
April 19, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28445110/normobaric-hypoxia-increases-the-growth-hormone-response-to-maximal-resistance-exercise-in-trained-men
#4
Dean Filopoulos, Stuart J Cormack, Douglas G Whyte
This study examined the effect of hypoxia on growth hormone (GH) release during an acute bout of high-intensity, low-volume resistance exercise. Using a single-blinded, randomised crossover design, 16 resistance-trained males completed two resistance exercise sessions in normobaric hypoxia (HYP; inspiratory oxygen fraction, (FiO2) 0.12, arterial oxygen saturation (SpO2) 82 ± 2%) and normoxia (NOR; FiO2 0.21, SpO2 98 ± 0%). Each session consisted of five sets of three repetitions of 45° leg press and bench press at 85% of one repetition maximum...
April 26, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28427551/cardiopulmonary-exercise-factors-predict-survival-in-patients-with-advanced-interstitial-lung-disease-referred-for-lung-transplantation
#5
Aimee M Layton, Hilary F Armstrong, Hanyoung P Kim, Kimbery S Meza, Frank D'Ovidio, Selim M Arcasoy
BACKGROUND: The purpose of this work was to determine if parameters assessed during Cardiopulmonary Exercise Testing (CPET) while using supplemental oxygen can independently predict one-year transplant-free survival in patients with Interstitial Lung Disease (ILD) referred for lung transplant evaluation. METHODS: We performed a chart review of patients with ILD who completed CPET with 30% FiO2 and gathered spirometry, pulmonary hemodynamic, six-minute walk, and CPET data...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28417842/blood-injection-injury-b-i-i-specific-phobia-affects-the-outcome-of-hypoxic-challenge-testing
#6
Kristofer J Spurling, Veronica P McGoldrick
BACKGROUND: Blood-injection-injury (B-I-I) phobia is capable of producing inaccurate hypoxic challenge testing results due to anxiety-induced hyperventilation. CASE REPORT: A 69-yr-old woman with a history of hypersensitivity pneumonitis, restrictive spirometry, exercise desaturation requiring supplementary oxygen on mobilizing, reduced DLco, and B-I-I phobia was referred for hypoxic challenge testing (HCT) to assess in-flight oxygen requirements. HCT was performed by breathing a 15% FIo2 gas mixture, simulating the available oxygen in ambient air onboard aircraft pressurized to an equivalent altitude of 8000 ft...
May 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28377402/assessing-initial-response-to-high-frequency-jet-ventilation-in-premature-infants-with-hypercapnic-respiratory-failure
#7
Craig R Wheeler, Craig D Smallwood, Iris O'Donnell, Daniel Gagner, Martha C Sola-Visner
BACKGROUND: High-frequency jet ventilation (HFJV) has been used in conjunction with conventional ventilation for infants with respiratory failure. We sought to identify parameters that were associated with successful application of HFJV in patients with hypercapnic respiratory failure. METHODS: A single-center, retrospective review of infants who received HFJV was conducted. Subjects were enrolled if birthweight was ≤2,000 g and capillary PCO2 was ≥55 mm Hg...
April 4, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28338405/physiological-responses-to-treadmill-running-with-body-weight-support-in-hypoxia-compared-to-normoxia
#8
Ben J Lee, Charles Douglas Thake
CONTEXT: Anecdotal reports suggest elite sports clubs combine lower body positive pressure (LBPP) rehabilitation with a hypoxic stimulus in order to maintain or increase physiological and metabolic strain, which are reduced during LBPP. However the effects of hypoxia on cardiovascular and metabolic response during LBPP rehabilitation is unknown. OBJECTIVE: Evaluate the use of normobaric hypoxia as a means to increase physiological strain during body weight supported (BWS) running...
March 24, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28302696/achievement-of-saturation-targets-in-preterm-infants-32%C3%A2-weeks-gestational-age-in-the-delivery-room
#9
Lani Nui White, Marta Thio, Louise S Owen, C Omar Kamlin, Samantha Sloss, Stuart B Hooper, Peter G Davis, Jennifer A Dawson
BACKGROUND: To reduce the risks of hypoxia and hyperoxia in preterm infants in the delivery room; national and international guidelines recommend titrating supplemental oxygen delivery to achieve specific oxygen saturation (SpO2) targets. Our aim was to measure the proportion of time infants <32 weeks' gestation spent within and outside prescribed SpO2 targets during the first 10 min after birth. METHOD: Prospective observational study using data from a preductal SpO2 sensor and oxygen analyser measuring fraction of inspired oxygen (FiO2) in the inspiratory limb of the respiratory circuit...
March 16, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28257415/rate-dependent-influence-of-arterial-desaturation-on-self-selected-exercise-intensity-during-cycling
#10
Saro D Farra, Stephen S Cheung, Scott G Thomas, Ira Jacobs
The purpose of this study was to clarify if Ratings of Perceived Exertion (RPE) and self-selected exercise intensity are sensitive not only to alterations in the absolute level of arterial saturation (SPO2) but also the rate of change in SPO2. Twelve healthy participants (31.6 ± 3.9 y, 175.5 ± 7.7 cm, 73.3 ± 10.3 kg, 51 ± 7 mL·kg-1·min-1 [Formula: see text]) exercised four times on a cycle ergometer, freely adjusting power output (PO) to maintain RPE at 5 on Borg's 10-point scale with no external feedback to indicate their exercise intensity...
2017: PloS One
https://www.readbyqxmd.com/read/28257375/searching-for-biomarkers-with-predictive-value-in-pediatric-acute-lung-injury-can-spo2-fio2-be-used-instead-of-pao2-fio2-as-an-index-to-predict-outcome
#11
Giuseppe A Marraro, Zeyang Li, Maria Antonella Piga
No abstract text is available yet for this article.
March 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28243206/spo2-and-heart-rate-during-a-real-hike-at-altitude-are-significantly-different-than-at-its-simulation-in-normobaric-hypoxia
#12
Nikolaus C Netzer, Linda Rausch, Arn H Eliasson, Hannes Gatterer, Matthias Friess, Martin Burtscher, Stephan Pramsohler
Rationale: Exposures to simulated altitude (normobaric hypoxia, NH) are frequently used in preparation for mountaineering activities at real altitude (hypobaric hypoxia, HH). However, physiological responses to exercise in NH and HH may differ. Unfortunately clinically useful information on such differences is largely lacking. This study therefore compared exercise responses between a simulated hike on a treadmill in NH and a similar field hike in HH. Methods: Six subjects (four men) participated in two trials, one in a NH chamber and a second in HH at an altitude of 4,205 m on the mountain Mauna Kea...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28225205/greater-endurance-capacity-and-improved-dyspnoea-with-acute-oxygen-supplementation-in-idiopathic-pulmonary-fibrosis-patients-without-resting-hypoxaemia
#13
Leona M Dowman, Christine F McDonald, Steven Bozinovski, Ross Vlahos, Rebecca Gillies, Dodie Pouniotis, Catherine J Hill, Nicole S L Goh, Anne E Holland
BACKGROUND AND OBJECTIVE: Supplemental oxygen is commonly prescribed in patients with idiopathic pulmonary fibrosis (IPF), although its benefits have not been proven. The aims of this study were to investigate the effect of oxygen on oxidative stress, cytokine production, skeletal muscle metabolism and physiological response to exercise in IPF. METHODS: Eleven participants with IPF received either oxygen, at an FiO2 of 0.50, or compressed air for 1 h at rest and during a cycle endurance test at 85% of peak work rate...
February 22, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28122489/feasibility-of-the-modified-sequential-organ-function-assessment-score-in-a-resource-constrained-setting-a-prospective-observational-study
#14
Cornelius Sendagire, Michael S Lipnick, Sam Kizito, Rebecca Kruisselbrink, Daniel Obua, Joseph Ejoku, Lameck Ssemogerere, Jane Nakibuuka, Arthur Kwizera
BACKGROUND: Sub-Saharan Africa has a great burden of critical illness with limited health care resources. We evaluated the feasibility and utility of the modified Sequential Organ Function Assessment (mSOFA) score in assessing morbidity and mortality in the National Referral Hospital's intensive care unit (ICU) for one year. METHODS: We conducted a prospective, observational cohort study on patients above 12 years of age admitted to the ICU at Mulago Hospital (Kampala, Uganda)...
January 26, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28121834/pao2-fio2-ratio-derived-from-the-spo2-fio2-ratio-to-improve-mortality-prediction-using-the-pediatric-index-of-mortality-3-score-in-transported-intensive-care-admissions
#15
Samiran Ray, Libby Rogers, Christina Pagel, Sainath Raman, Mark J Peters, Padmanabhan Ramnarayan
OBJECTIVES: To derive a relationship between the SpO2/FIO2 ratio and PaO2/FIO2 ratio across the entire range of SpO2 values (0-100%) and to evaluate whether mortality prediction using the Pediatric Index of Mortality-3 can be improved by the use of PaO2/FIO2 values derived from SpO2/FIO2. DESIGN: Retrospective analysis of prospectively collected data. SETTING: A regional PICU transport service. PATIENTS: Children transported to a PICU...
March 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28118771/risk-factors-associated-with-failure-of-extubation-in-very-low-birth-weight-newborns
#16
Slobodan Spasojevic, Aleksandra Doronjski
AIM: To identify risk factors associated with the failure of extubation of mechanically ventilated very-low-birth-weight newborns. STUDY DESIGN: Prospective observational study. Assessment of the occurrence of extubation failure in relation to demographic and ventilation parameters, the SpO2/FiO2 ratio, the spontaneous breathing test (SBT) and values of the Silverman-Andersen score (SAS). Extubation failure was defined as the need for reintubation for any reason within 72 h after extubation...
February 21, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28096239/skin-to-skin-care-in-preterm-infants-receiving-respiratory-support-does-not-lead-to-physiological-instability
#17
Laila Lorenz, Jennifer A Dawson, Hannah Jones, Susan E Jacobs, Jeanie L Cheong, Susan M Donath, Peter G Davis, C Omar F Kamlin
OBJECTIVE: Providing skin-to-skin care (SSC) to preterm infants is standard practice in many neonatal intensive care units. There are conflicting reports on the stability of oxygen saturation (SpO2) during SSC, which may create a barrier to a wider implementation of SSC to infants receiving respiratory support. Regional cerebral oxygenation (rcO2) measured using near-infrared spectroscopy can serve as a surrogate parameter for cerebral oxygen delivery and consumption. We hypothesised that rcO2 during SSC would be similar to standard care in preterm infants receiving respiratory support...
January 17, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28068656/mechanisms-of-improved-exercise-performance-under-hyperoxia
#18
Silvia Ulrich, Elisabeth D Hasler, Séverine Müller-Mottet, Stephan Keusch, Michael Furian, Tsogyal D Latshang, Simon Schneider, Stéphanie Saxer, Konrad E Bloch
BACKGROUND: The impact of hyperoxia on exercise limitation is still incompletely understood. OBJECTIVES: We investigated to which extent breathing hyperoxia enhances the exercise performance of healthy subjects and which physiologic mechanisms are involved. METHODS: A total of 32 healthy volunteers (43 ± 15 years, 12 women) performed 4 bicycle exercise tests to exhaustion with ramp and constant-load protocols (at 75% of the maximal workload [Wmax] on FiO2 0...
2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28012013/ventilation-perfusion-ratio-and-right-to-left-shunt-in-healthy-newborn-infants
#19
Theodore Dassios, Kamal Ali, Thomas Rossor, Anne Greenough
Oxygenation impairment can be assessed non-invasively by determining the degree of right-to-left shunt and ventilation/perfusion (VA/Q) inequality. These indices have been used in sick newborn infants, but normative values have not been reported which are essential to determine the magnitude of the abnormality. We, therefore, aimed to measure the shunt and VA/Q in infants with no history of respiratory conditions and determine if there was any effect of supine or prone position and the reproducibility of the data...
December 23, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28003557/comparing-the-effects-of-two-different-levels-of-hyperoxygenation-on-gas-exchange-during-open-endotracheal-suctioning-a-randomized-crossover-study
#20
Jacqueline Rodrigues de Freitas Vianna, Valéria Amorim Pires Di Lorenzo, Miléa Mara Lourenço da Silva Simões, Maurício Jamami
BACKGROUND: Endotracheal suctioning is required for mechanically ventilated patients to maintain a patent airway. Studies show that open endotracheal suctioning affects respiratory mechanics and gas exchange. The aim of this study was to compare the effectiveness of hyperoxygenation with FIO2 + 0.20 above baseline and hyperoxygenation with FIO2 1.0 in preventing hypoxemia, and to determine the impact of open endotracheal suctioning on the pulmonary ventilation of critical subjects receiving mechanical ventilatory support...
January 2017: Respiratory Care
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