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https://www.readbyqxmd.com/read/28534857/optimization-based-sensor-fusion-of-gnss-and-imu-using-a-moving-horizon-approach
#1
Fabian Girrbach, Jeroen D Hol, Giovanni Bellusci, Moritz Diehl
The rise of autonomous systems operating close to humans imposes new challenges in terms of robustness and precision on the estimation and control algorithms. Approaches based on nonlinear optimization, such as moving horizon estimation, have been shown to improve the accuracy of the estimated solution compared to traditional filter techniques. This paper introduces an optimization-based framework for multi-sensor fusion following a moving horizon scheme. The framework is applied to the often occurring estimation problem of motion tracking by fusing measurements of a global navigation satellite system receiver and an inertial measurement unit...
May 19, 2017: Sensors
https://www.readbyqxmd.com/read/28530166/quorum-sensing-and-rsam-regulons-of-the-rice-pathogen-pseudomonas-fuscovaginae
#2
Gordana Uzelac, Hitendra Kumar Patel, Giulia Devescovi, Danilo Licastro, Vittorio Venturi
Pseudomonas fuscovaginae (Pfv) is an emerging plant pathogen causing sheath brown rot in rice, as well as diseases in other gramineae food crops including maize, sorghum and wheat. Pfv possesses two conserved N-acyl homoserine lactone (AHL) quorum sensing (QS) systems called PfvI/R and PfsI/R, which are repressed by RsaL and RsaM, respectively. The two systems are not hierarchically organized and are involved in plant virulence. In this study the AHL QS PfsI/R, PfvI/R and RsaM regulons were determined by transcriptomic analysis...
May 22, 2017: Microbiology
https://www.readbyqxmd.com/read/28521872/non-alcoholic-fatty-liver-disease-an-update-with-special-focus-on-the-role-of-gut-microbiota
#3
REVIEW
Michael Doulberis, Georgios Kotronis, Dimitra Gialamprinou, Jannis Kountouras, Panagiotis Katsinelos
Non-alcoholic fatty liver disease (NAFLD) is a significant global health burden in children, adolescents and adults with substantial rise in prevalence over the last decades. Accumulating data from manifold studies support the idea of NAFLD as a hepatic manifestation of metabolic syndrome, being rather a systemic metabolic disease than a liver confined pathology. Emerging data support that the gut microbiome represents a significant environmental factor contributing to NAFLD development and progression. Apart from other regimens, probiotics may have a positive role in the management of NAFLD through a plethora of possible mechanisms...
June 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28520958/the-development-use-and-impact-of-a-global-laboratory-database-during-the-2014-ebola-outbreak-in-west-africa
#4
Kara N Durski, Shalini Singaravelu, Junxiong Teo, Dhamari Naidoo, Luke Bawo, Amara Jambai, Sakoba Keita, Ali Ahmed Yahaya, Beatrice Muraguri, Brice Ahounou, Victoria Katawera, Fredson Kuti-George, Yacouba Nebie, T Henry Kohar, Patrick Jowlehpah Hardy, Mamoudou Harouna Djingarey, David Kargbo, Nuha Mahmoud, Yewondwossen Assefa, Orla Condell, Magassouba N'Faly, Leon Van Gurp, Margaret Lamanu, Julia Ryan, Boubacar Diallo, Foday Daffae, Dikena Jackson, Fayyaz Ahmed Malik, Philomena Raftery, Pierre Formenty
Background: The international impact, rapid widespread transmission, and reporting delays during the 2014 Ebola virus disease (EVD) outbreak in West Africa highlighted the need for a global, centralized database to inform outbreak response. The World Health Organization and Emerging and Dangerous Pathogens Laboratory Network addressed this need by supporting the development of a global laboratory database. Methods: Specimens were collected in the affected countries from patients and dead bodies meeting the case definitions for EVD...
May 18, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28513801/validity-and-reliability-of-a-telephone-survey-of-physical-activity-in-brazil
#5
Alexandra Dias Moreira, Rafael Moreira Claro, Mariana Santos Felisbino-Mendes, Gustavo Velasquez-Melendez
Introduction: Physical activity in Brazil is assessed by the Telephone-based Risk Factor Surveillance System for Chronic Diseases (VIGITEL). Objectives: To evaluate the reliability and concurrent validity of VIGITEL physical activity indicators. Methods: For the reliability study, 305 individuals responded to VIGITEL interviews, which were repeated with intervals of 7 - 15 days, in Belo Horizonte, 2013. The evaluated indicators included "sufficiently active on leisure time," "active in transportation," "inactive in four domains of physical activity (leisure, work, transportation, and housework)," and "watching TV for long periods...
January 2017: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/28512449/antibacterial-potential-of-an-antimicrobial-agent-inspired-by-peroxidase-catalyzed-systems
#6
Lilit Tonoyan, Gerard T A Fleming, Paul H Mc Cay, Ruairi Friel, Vincent O'Flaherty
Antibiotic resistance is an increasingly serious threat to global health. Consequently, the development of non-antibiotic based therapies and disinfectants, which avoid induction of resistance, or cross-resistance, is of high priority. We report the synthesis of a biocidal complex, which is produced by the reaction between ionic oxidizable salts-iodide and thiocyanate-in the presence of hydrogen peroxide as an oxidation source. The reaction generates bactericidal reactive oxygen and iodine species. In this study, we report that the iodo-thiocyanate complex (ITC) is an effective bactericidal agent with activity against planktonic and biofilm cells of Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus and methicillin-resistant S...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28510582/the-worst-case-scenario-locomotor-and-collision-demands-of-the-longest-periods-of-gameplay-in-professional-rugby-union
#7
Cillian Reardon, Daniel P Tobin, Peter Tierney, Eamonn Delahunt
A number of studies have used global positioning systems (GPS) to report on positional differences in the physical game demands of rugby union both on an average and singular bout basis. However, the ability of these studies to report quantitative data is limited by a lack of validation of certain aspects of measurement by GPS micro-technology. Furthermore no study has analyzed the positional physical demands of the longest bouts of ball-in-play time in rugby union. The aim of the present study is to compare the demands of the single longest period of ball-in-play, termed "worst case scenario" (WCS) between positional groups, which have previously been reported to have distinguishable game demands...
2017: PloS One
https://www.readbyqxmd.com/read/28510538/measuring-and-assessing-individual-external-doses-during-the-rehabilitation-phase-in-iitate-village-after-the-fukushima-daiichi-nuclear-power-plant-accident
#8
Wataru Naito, Motoki Uesaka, Tadahiro Kurosawa, Yujiro Kuroda
After the Fukushima Daiichi Nuclear Power Plant accident in 2011, Iitate village was placed under an evacuation order because the level of radioactive materials drifting from the nuclear plant to the village were above a government-set level for allowing residents to live in the area. The evacuation advisory for most of the village was lifted on March 31, 2017. For displaced residents deciding whether or not to return to their homes, it is important to correctly understand and estimate the realistic individual external doses they will receive after returning to the village...
May 16, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28508359/evolving-relevance-of-neuroproteomics-in-alzheimer-s-disease
#9
Simone Lista, Henrik Zetterberg, Sid E O'Bryant, Kaj Blennow, Harald Hampel
Substantial progress in the understanding of the biology of Alzheimer's disease (AD) has been achieved over the past decades. The early detection and diagnosis of AD and other age-related neurodegenerative diseases, however, remain a challenging scientific frontier. Therefore, the comprehensive discovery (relating to all individual, converging or diverging biochemical disease mechanisms), development, validation, and qualification of standardized biological markers with diagnostic and prognostic functions with a precise performance profile regarding specificity, sensitivity, and positive and negative predictive value are warranted...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28504628/-the-current-global-tuberculosis-state
#10
Christian Wejse, Troels Lillebæk, Ole Kirk, Pernille Ravn, Isik Somuncu Johansen, Åse Bengård Andersen
Despite an increase in the total number of tuberculosis (TB) patients globally, positive trends in reduction of prevalence and mortality are observed. However, high numbers of drug-resistant cases are threatening this trend. Multidrug-resistant and extensively resistant cases constitute an increasing challenge in many parts of the world also within the European region - especially in former Sovjet Republic nations. Point-of-care test systems potentially replacing microscopy and urine antigen detection systems are currently launched in many TB-high endemic countries improving TB detection rates...
May 15, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28502844/a-novel-approach-to-map-induced-activation-of-neuronal-networks-using-chemogenetics-and-functional-neuroimaging-in-rats-a-proof-of-concept-study-on-the-mesocorticolimbic-system
#11
Theresia J M Roelofs, Jeroen P H Verharen, Geralda A F van Tilborg, Linde Boekhoudt, Annette van der Toorn, Johannes W de Jong, Mieneke C M Luijendijk, Willem M Otte, Roger A H Adan, Rick M Dijkhuizen
Linking neural circuit activation at whole-brain level to neuronal activity at cellular level remains one of the major challenges in neuroscience research. We set up a novel functional neuroimaging approach to map global effects of locally induced activation of specific midbrain projection neurons using chemogenetics (Designer Receptors Exclusively Activated by Designer Drugs (DREADD)-technology) combined with pharmacological magnetic resonance imaging (phMRI) in the rat mesocorticolimbic system. Chemogenetic activation of DREADD-targeted mesolimbic or mesocortical pathways, i...
May 11, 2017: NeuroImage
https://www.readbyqxmd.com/read/28500065/loss-of-mpdz-impairs-ependymal-cell-integrity-leading-to-perinatal-onset-hydrocephalus-in-mice
#12
Anja Feldner, M Gordian Adam, Fabian Tetzlaff, Iris Moll, Dorde Komljenovic, Felix Sahm, Tobias Bäuerle, Hiroshi Ishikawa, Horst Schroten, Thomas Korff, Ilse Hofmann, Hartwig Wolburg, Andreas von Deimling, Andreas Fischer
Hydrocephalus is a common congenital anomaly. LCAM1 and MPDZ (MUPP1) are the only known human gene loci associated with non-syndromic hydrocephalus. To investigate functions of the tight junction-associated protein Mpdz, we generated mouse models. Global Mpdz gene deletion or conditional inactivation in Nestin-positive cells led to formation of supratentorial hydrocephalus in the early postnatal period. Blood vessels, epithelial cells of the choroid plexus, and cilia on ependymal cells, which line the ventricular system, remained morphologically intact in Mpdz-deficient brains...
May 12, 2017: EMBO Molecular Medicine
https://www.readbyqxmd.com/read/28498940/contribution-of-aerobic-anoxygenic-phototrophic-bacteria-to-total-organic-carbon-pool-in-aquatic-system-of-subtropical-karst-catchments-southwest-china-evidence-from-hydrochemical-and-microbiological-study
#13
Qiang Li, Ang Song, Wenjie Peng, Zhenjiang Jin, Werner E G Müller, Xiaohong Wang
Aerobic anoxygenic phototrophic bacteria may play a particular role in carbon cycling of aquatic systems. However, little is known about the interaction between aerobic anoxygenic phototrophic bacteria and hydrochemistry in groundwater-surface water exchange systems of subtropical karst catchments. We carried out a detailed study on the abundance of aerobic anoxygenic phototrophic bacteria and bacterioplankton, hydrochemistry and taxonomy of bacterioplankton in the Maocun watershed, Southwest China, an area with karst geological background...
May 11, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/28497245/single-species-growth-consuming-inorganic-carbon-with-internal-storage-in-a-poorly-mixed-habitat
#14
Sze-Bi Hsu, King-Yeung Lam, Feng-Bin Wang
This paper presents a PDE system modeling the growth of a single species population consuming inorganic carbon that is stored internally in a poorly mixed habitat. Inorganic carbon takes the forms of "CO2" (dissolved CO2 and carbonic acid) and "CARB" (bicarbonate and carbonate ions), which are substitutable in their effects on algal growth. We first establish a threshold type result on the extinction/persistence of the species in terms of the sign of a principal eigenvalue associated with a nonlinear eigenvalue problem...
May 11, 2017: Journal of Mathematical Biology
https://www.readbyqxmd.com/read/28496395/a-relative-quantitative-positive-negative-ion-switching-method-for-untargeted-lipidomics-via-high-resolution-lc-ms-ms-from-any-biological-source
#15
Susanne B Breitkopf, Stéphane J H Ricoult, Min Yuan, Ying Xu, David A Peake, Brendan D Manning, John M Asara
INTRODUCTION: Advances in high-resolution mass spectrometry have created renewed interest for studying global lipid biochemistry in disease and biological systems. OBJECTIVES: Here, we present an untargeted 30 min. LC-MS/MS platform that utilizes positive/negative polarity switching to perform unbiased data dependent acquisitions (DDA) via higher energy collisional dissociation (HCD) fragmentation to profile more than 1000-1500 lipid ions mainly from methyl-tert-butyl ether (MTBE) or chloroform:methanol extractions...
March 2017: Metabolomics: Official Journal of the Metabolomic Society
https://www.readbyqxmd.com/read/28494438/assessment-of-intra-and-inter-rater-reliability-of-three-methods-for-measuring-atopic-dermatitis-severity-easi-objective-scorad-and-iga
#16
Agnieszka Bożek, Adam Reich
BACKGROUND: Numerous different scoring systems have been proposed for assessing the severity of atopic dermatitis (AD). Many of these methods did not undergo proper validation and reliability testing. OBJECTIVE: The aim of our study was to compare the reliability and reproducibility of the Eczema Area and Severity Index (EASI), objective Scoring Atopic Dermatitis (oSCORAD), and Investigator Global Assessment (IGA). METHODS: On the scoring day, 10 trained dermatologists evaluated 10 adult patients with AD using the EASI, oSCORAD, and IGA...
May 12, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28488913/relationship-between-pre-training-subjective-wellness-measures-player-load-and-rating-of-perceived-exertion-training-load-in-american-college-football
#17
Andrew D Govus, Aaron Coutts, Rob Duffield, Andrew Murray, Hugh Fullagar
PURPOSE: The relationship between pre-training subjective wellness, external and internal training load in American College football is unclear. This study examined the relationship between pre-training subjective wellness (sleep quality, muscle soreness, energy, wellness Z score) on 1) player load and 2) session rating of perceived exertion (s-RPE-TL) in American College footballers. METHODS: Subjective wellness (measured using 5-point, Likert scale questionnaires); external load (derived from global position systems [GPS] and accelerometry) and s-RPE-TL were collected during three typical training sessions per week for the second half of an American collegiate football season (eight weeks)...
May 10, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28487511/a-local-counter-regulatory-motif-modulates-the-global-phase-of-hormonal-oscillations
#18
Dong-Ho Park, Taegeun Song, Danh-Tai Hoang, Jin Xu, Junghyo Jo
Counter-regulatory elements maintain dynamic equilibrium ubiquitously in living systems. The most prominent example, which is critical to mammalian survival, is that of pancreatic α and β cells producing glucagon and insulin for glucose homeostasis. These cells are not found in a single gland but are dispersed in multiple micro-organs known as the islets of Langerhans. Within an islet, these two reciprocal cell types interact with each other and with an additional cell type: the δ cell. By testing all possible motifs governing the interactions of these three cell types, we found that a unique set of positive/negative intra-islet interactions between different islet cell types functions not only to reduce the superficially wasteful zero-sum action of glucagon and insulin but also to enhance/suppress the synchronization of hormone secretions between islets under high/normal glucose conditions...
May 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28484046/exploring-the-%C3%AE-ctd-amino-acid-residue-requirements-for-productive-interaction-between-spx-and-rna-polymerase-of-bacillus-subtilis
#19
Cierra Birch, Madison Davis, Lea Mbengi, Peter Zuber
Bacillus subtilis Spx is a global transcriptional regulator that is conserved among gram-positive bacteria, in which Spx is required for preventing oxidatively induced proteotoxicity. Upon stress induction, Spx engages RNA polymerase (RNAP) through interaction with the C-terminal domain of the rpoA-encoded RNAP α subunit (αCTD). Previous mutational analysis of rpoA revealed that substitutions of Y263 in αCTD severely impaired Spx-activated transcription. Attempts to substitute alanine for αCTD R261, R268, R289, E255, E298 and K294 were unsuccessful, suggesting that these residues are essential...
May 8, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28480691/profile-of-match-performance-and-heart-rate-response-in-japanese-amputee-soccer
#20
Hirofumi Maehana, Aya Miyamoto, Kenichi Koshiyama, Toshio Tanaka Yanagiya, Masafumi Yoshimura
BACKGROUND: The purpose of this study was to profile the match performance and heart rate response in Japanese amputee soccer. METHODS: Twelve amputee soccer players participated in this study. Match data were collected 20 samples in 4 matches. Match performances data such as total distance, high-intensity running (HIR: ≥13km·h-1) were collected using a global positioning systems technology. Heart rate (HR) was recorded using short-range radio telemetry. In addition, the rating of perceived exertion (RPE) was assessed immediately using Borg's original after the first half and the second half...
May 5, 2017: Journal of Sports Medicine and Physical Fitness
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