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https://www.readbyqxmd.com/read/27833704/superior-orbital-fissure-syndrome-in-lateral-orbital-wall-fracture-management-and-classification-update
#1
REVIEW
Claudio Caldarelli, Rodolfo Benech, Caterina Iaquinta
The superior orbital fissure syndrome (SOFS) is an uncommon complication rarely occurring in association with craniofacial trauma. Work-up of a patient injured by a traumatic right orbitozygomatic complex fracture and SOFS is presented. Accurate computed tomography scan and three-dimensional reconstruction showed a medial displacement of the lateral orbital wall, compressing the right superior orbital fissure (SOF), without intraorbital bone fragment displacement or hemorrhage. Imaging also revealed a frontosphenotemporal fracture, according to Pellerin et al, that is, frequently associated with visual impairment...
November 2016: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/27797797/infrarenal-aortic-clamp-reviving-a-patient-from-acute-surgical-haemorrhagic-shock-a-novel-management-technique
#2
Ranjith Kumar, M V S Satya Prakash, Subhasree Das, Ramanitharan Manikandan
Surgical management of renal cell carcinoma extending into the inferior vena cava (IVC) is almost always accompanied by massive intraoperative blood loss and associated complications. It is a widely recognised problem, and its active management is essential in improving the perioperative morbidity and mortality. We share our experience with a similar case of open radical nephrectomy with massive blood loss of twice the circulating volume in a duration of <8 surgical hours. Although we emphasise the goals of securing haemostasis, restoration of circulating volume, and efficient management by replacing blood components, in the present case, despite the above-mentioned goals being fulfilled, we were unable to extricate the patient from haemorrhagic shock by conventional means and therefore resorted to desperate measures, namely the novel approach of infrarenal aortic clamping along with higher than recommended vasopressor support...
October 19, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27794594/metallation-triggers-single-crystalline-order-in-a-porous-solid
#3
Yun-Long Hou, Ka-Kit Yee, Yan-Lung Wong, Meiqin Zha, Jun He, Matthias Zeller, Allen D Hunter, Kaiqi Yang, Zhengtao Xu
We report the dramatic triggering of structural order in a Zr(IV)-based metal-organic framework (MOF) through docking of HgCl2 guests. While as-made crystals were unsuitable for single crystal X-ray diffraction (SCXRD), with diffraction limited to low angles well below atomic resolution due to intrinsic structural disorder; permeation of HgCl2 not only leaves the crystals intact, but resulted in fully resolved backbone as well as thioether side groups, revealing elaborate HgCl2-thioether aggregates nested within the host octahedra to form a hierarchical, multi-functional net...
October 31, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/27753548/forty-years-on-from-an-event-that-changed-the-management-of-trauma-around-the-world-what-actually-happened-that-night-forty-years-ago
#4
Franklin H G Bridgewater
The management of trauma has evolved significantly over the last 40 years. Seminal to this process was the development in Nebraska of a concept of trauma management that was promulgated as Advanced Trauma Life Support (ATLS). It has achieved global support and is considered by many to be the acme in trauma management. Every participant in an ATLS course remembers that an aviation accident in rural Nebraska was responsible for the nascence of the program but very few know the details of the crash. February 17, 2016, was the 40th anniversary of the accident...
October 2016: Military Medicine
https://www.readbyqxmd.com/read/27748690/cervical-spine-immobilization-during-extrication-of-the-awake-patient-a-narrative-review
#5
Alan Cowley, Ashley Hague, Neal Durge
Techniques for extricating vehicle occupants after road-traffic collisions have evolved largely through fear of worsening a cervical spine injury, rather than being evidence-based. Recent research has looked at the safety of allowing the alert patient to self-extricate, rather than being assisted with equipment such as long spinal boards and semirigid cervical collars. This review aims to elucidate whether it is safe to allow an alert, ambulant patient to self-extricate from a vehicle with minimal or no cervical spine immobilization...
September 29, 2016: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/27635250/the-resource-utilisation-of-medically-unexplained-physical-symptoms
#6
Kimberley Lee, Malcolm H Johnson, Julie Harris, Frederick Sundram
OBJECTIVES: As patients with medically unexplained physical symptoms may present frequently to hospital settings and receive potentially unnecessary investigations and treatments, we aimed to assess the frequency and type of medically unexplained physical symptoms presentations to clinical services and estimate the associated direct healthcare costs. METHODS: This study was undertaken at the largest district health board in New Zealand. All patients with a diagnosed presentation of medically unexplained physical symptoms in 2013 were identified using the district health board's clinical coding system...
2016: SAGE Open Medicine
https://www.readbyqxmd.com/read/27634704/loss-of-consciousness-during-single-sling-helicopter-hoist-rescue-resulting-in-a-fatal-fall
#7
Jessie Biles, Alan A Garner
INTRODUCTION: Although harness suspension trauma has been documented since the 1960s, especially in the mountaineering setting, there is little robust medical research into the area. Helicopter hoist rescue shares similar risks and is reserved for those cases that cannot be accessed safely by other routes, where extrication may be hazardous or will take an unreasonable amount of time. The single sling or chest harness used for hoist rescue is a single harness around the upper torso and is easier and quicker to apply than a stretcher...
September 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/27615346/triad-of-death-the-importance-of-temperature-monitoring-in-trauma-patients
#8
Matthew Keane
Multiple organ failure is a significant complication in traumatic injury, and can be exacerbated by a failure to adequately monitor and control trauma patients' core body temperature in emergency departments (EDs). Nearly half of trauma patients are hypothermic on arrival at emergency departments, often due to factors beyond the control of emergency service responders and during on-scene resuscitation attempts. This article examines the physiology of the 'triad of death' -hypothermia, metabolic acidosis and coagulopathy - to highlight the importance of monitoring and maintaining normothermia, or normal body temperature, which is between 36°C and 37...
September 2016: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/27450044/pressure-ulcer-development-in-trauma-patients-with-suspected-spinal-injury-the-influence-of-risk-factors-present-in-the-emergency-department
#9
H W Wietske Ham, L Lisette Schoonhoven, M Marieke J Schuurmans, L Luke P H Leenen
OBJECTIVES: To explore the influence of risk factors present at Emergency Department admission on pressure ulcer development in trauma patients with suspected spinal injury, admitted to the hospital for evaluation and treatment of acute traumatic injuries. DESIGN: Prospective cohort study setting level one trauma center in the Netherlands participants adult trauma patients transported to the Emergency Department on a backboard, with extrication collar and headblocks and admitted to the hospital for treatment or evaluation of their injuries...
July 19, 2016: International Emergency Nursing
https://www.readbyqxmd.com/read/27377920/hems-in-alpine-rescue-for-pediatric-emergencies
#10
Stefan Taubenböck, Wolfgang Lederer, Marc Kaufmann, Gunnar Kroesen
OBJECTIVE: The objective of this study was to describe the pediatric emergencies encountered by the Christophorus-1 helicopter emergency medical service (HEMS) during a period of 2 years. METHODS: Emergency treatment of pediatric casualties by HEMS was evaluated at a helicopter base. Children up to 14 years who were treated by HEMS emergency physicians from Christophorus-1 during primary missions in the alpine region were retrospectively enrolled. RESULTS: Of the 1314 HEMS operations conducted during a 2-year investigation period, pediatric emergencies accounted for 114 (8...
September 2016: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/27373059/summary-of-auger-related-entanglement-incidents-occurring-inside-agricultural-confined-spaces
#11
Y H Cheng, W E Field
Entanglements in energized equipment, including augers found in agricultural workplaces, have historically been a significant cause of traumatic injury. Incidents involving augers located inside agricultural confined spaces (primarily grain storage structures and forage silos), although relatively rare events, are a widely recognized problem due to the relative severity of the resulting injuries and the complexities of victim extrication. However, this problem is neither well documented nor elucidated in the research literature, other than anecdotal observations relating to medical treatment of auger-related injuries and citations for non-compliance with federal and state workplace safety regulations...
April 2016: Journal of Agricultural Safety and Health
https://www.readbyqxmd.com/read/27312137/burial-duration-depth-and-air-pocket-explain-avalanche-survival-patterns-in-austria-and-switzerland
#12
Emily Procter, Giacomo Strapazzon, Tomas Dal Cappello, Benjamin Zweifel, Andreas Würtele, Andreas Renner, Markus Falk, Hermann Brugger
AIM: To calculate the first Austrian avalanche survival curve and update a Swiss survival curve to explore survival patterns in the Alps. METHODS: Avalanche accidents occurring between 2005/06 and 2012/13 in Austria and Switzerland were collected. Completely buried victims (i.e. burial of the head and chest) in open terrain with known outcome (survived or not survived) were included in the analysis. Extrication and survival curves were calculated using the Turnbull algorithm, as in previous studies...
August 2016: Resuscitation
https://www.readbyqxmd.com/read/27274242/vesicular-liposomal-and-nanoparticulated-delivery-of-curcumin-a-comparative-study-on-carbon-tetrachloride-mediated-oxidative-hepatocellular-damage-in-rat-model
#13
Somsubhra Thakur Choudhury, Nirmalendu Das, Swarupa Ghosh, Debasree Ghosh, Somsuta Chakraborty, Nahid Ali
The liver plays a vital role in biotransforming and extricating xenobiotics and is thus prone to their toxicities. Short-term administration of carbon tetrachloride (CCl4) causes hepatic inflammation by enhancing cellular reactive oxygen species (ROS) level, promoting mitochondrial dysfunction, and inducing cellular apoptosis. Curcumin is well accepted for its antioxidative and anti-inflammatory properties and can be considered as an effective therapeutic agent against hepatotoxicity. However, its therapeutic efficacy is compromised due to its insolubility in water...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27265929/the-hartford-consensus-iv-a-call-for-increased-national-resilience
#14
Lenworth M Jacobs
Despite advances in the response to active shooter and intentional mass casualty events, a gap remains in our national preparedness and resilience. Drawing from experiences at myriad mass casualty events, the immediate responder (volunteer responder) represents an underutilized resource, yet one capable of dramatically increasing our all-hazards (injuries from all natural and man-made causes) national resilience. The overarching principle of the Hartford Consensus, outlined in previous reports, is that no one should die from uncontrolled bleeding...
April 2016: Connecticut Medicine
https://www.readbyqxmd.com/read/27261454/the-influence-of-anthropometrics-on-physical-employment-standard-performance
#15
T Reilly, M Spivock, A Prayal-Brown, B Stockbrugger, R Blacklock
BACKGROUND: The Canadian Armed Forces (CAF) recently implemented the Fitness for Operational Requirements of CAF Employment (FORCE), a new physical employment standard (PES). Data collection throughout development included anthropometric profiles of the CAF. AIMS: To determine if anthropometric measurements and demographic information would predict the performance outcomes of the FORCE and/or Common Military Task Fitness Evaluation (CMTFE). METHODS: We conducted a secondary analysis of data from FORCE research...
October 2016: Occupational Medicine
https://www.readbyqxmd.com/read/27217060/identification-of-an-activation-site-in-bak-and-mitochondrial-bax-triggered-by-antibodies
#16
Sweta Iyer, Khatira Anwari, Amber E Alsop, Wai Shan Yuen, David C S Huang, John Carroll, Nicholas A Smith, Brian J Smith, Grant Dewson, Ruth M Kluck
During apoptosis, Bak and Bax are activated by BH3-only proteins binding to the α2-α5 hydrophobic groove; Bax is also activated via a rear pocket. Here we report that antibodies can directly activate Bak and mitochondrial Bax by binding to the α1-α2 loop. A monoclonal antibody (clone 7D10) binds close to α1 in non-activated Bak to induce conformational change, oligomerization, and cytochrome c release. Anti-FLAG antibodies also activate Bak containing a FLAG epitope close to α1. An antibody (clone 3C10) to the Bax α1-α2 loop activates mitochondrial Bax, but blocks translocation of cytosolic Bax...
2016: Nature Communications
https://www.readbyqxmd.com/read/27158006/pressure-ulcers-indentation-marks-and-pain-from-cervical-spine-immobilization-with-extrication-collars-and-headblocks-an-observational-study
#17
Wietske H W Ham, Lisette Schoonhoven, Marieke J Schuurmans, Luke P H Leenen
OBJECTIVES: To describe the occurrence and severity of pressure ulcers, indentation marks and pain from the extrication collar combined with headblocks. Furthermore, the influence of time, injury severity and patient characteristics on the development of pressure ulcers, indentation marks and pain was explored. DESIGN: Observational. STUDY SETTING: Level one trauma centre in the Netherlands. PARTICIPANTS: Adult trauma patients admitted to the Emergency Department in an extrication collar combined with headblocks...
September 2016: Injury
https://www.readbyqxmd.com/read/27140319/body-positioning-of-buried-avalanche-victims
#18
Daniel K Kornhall, Spencer Logan, Thomas Dolven
OBJECTIVE: The immediate medical management of buried avalanche victims will to some extent be dictated by the victim's body positioning in the snow. Medical personnel are trained to assess and manage victims in a supine body position. Furthermore, avalanche first responders are trained to handle extricated avalanche victims carefully out of concerns for causing hemodynamic instability or for aggravating spinal injury. Thus, locating and extricating avalanche victims in positions other than supine has the potential to complicate immediate medical management...
June 2016: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/27116920/avalanche-survival-after-rescue-with-the-recco-rescue-system-a-case-report
#19
Katharina Grasegger, Giacomo Strapazzon, Emily Procter, Hermann Brugger, Inigo Soteras
We report a case of survival of a completely buried avalanche victim after being located with the radar-based RECCO Rescue System. In the winter of 2015, 2 off-piste skiers were completely buried in an avalanche near the secured ski area in Baqueira Beret, Spain. The first victim was located with the RECCO Rescue System in less than 35 minutes and was alive and conscious at extrication. This system emits radio waves and requires a specific reflector. It is a portable device that is used by more than 600 rescue organizations worldwide, especially in secured ski areas...
June 2016: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/27076143/the-design-of-a-clostridium-difficile-carbohydrate-based-vaccine
#20
Mario A Monteiro
Clostridium difficile vaccines composed of surface polysaccharides (PSs) have the potential to simultaneously control infection and colonization levels in humans. Hot water-phenol treatment of C. difficile biomass can extricate water-soluble PS-I and PS-II; and water- and phenol-soluble PS-III. C. difficile vaccines based on PS-II have attracted the most attention due its facile purification and ubiquitous expression by C. difficile ribotypes. Anti PS-II antibodies recognize both C. difficile vegetative cell and sporulating preparations and confer protection against C...
2016: Methods in Molecular Biology
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