keyword
https://read.qxmd.com/read/38361717/posterior-reversible-encephalopathy-syndrome-pres-and-the-uncommon-sequela-mesial-temporal-sclerosis
#21
Abraham Mengstu, Mathew N Chakko, Blake Salisbury, Jibran Fateh
Posterior reversible encephalopathy syndrome is often linked to conditions like hypertension and is characterized by reversible brain edema. The development of mesial temporal sclerosis as a consequence of posterior reversible encephalopathy syndrome is an uncommon clinical outcome.  We report a 48-year-old female who initially presented with severe iron deficiency anemia, hypertension, and septic tenosynovitis requiring surgical drainage with subsequent development of posterior reversible encephalopathy syndrome accompanied by endocarditis...
January 2024: Curēus
https://read.qxmd.com/read/38356649/fecal-supernatants-from-dogs-with-idiopathic-epilepsy-activate-enteric-neurons
#22
JOURNAL ARTICLE
Kristin Elfers, Antja Watanangura, Pascal Hoffmann, Jan S Suchodolski, Mohammad R Khattab, Rachel Pilla, Sebastian Meller, Holger A Volk, Gemma Mazzuoli-Weber
INTRODUCTION: Alterations in the composition and function of the gut microbiome have been reported in idiopathic epilepsy (IE), however, interactions of gut microbes with the enteric nervous system (ENS) in this context require further study. This pilot study examined how gastrointestinal microbiota (GIM), their metabolites, and nutrients contained in intestinal contents communicate with the ENS. METHODS: Fecal supernatants (FS) from healthy dogs and dogs with IE, including drug-naïve, phenobarbital (PB) responsive, and PB non-responsive dogs, were applied to cultured myenteric neurons to test their activation using voltage-sensitive dye neuroimaging...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38353525/ilae-neuroimaging-task-force-highlight-subcortical-laminar-heterotopia
#23
JOURNAL ARTICLE
Burkhard S Kasper, John Archer, Boris C Bernhardt, Lorenzo Caciagli, Fernando Cendes, Yotin Chinvarun, Luis Concha, Paolo Federico, William Gaillard, Eliane Kobayashi, Godwin Ogbole, Anna Elisabetta Vaudano, Irene Wang, Shuang Wang, Gavin P Winston, Stefan Rampp
The ILAE Neuroimaging Task Force publishes educational case reports that highlight basic aspects of neuroimaging in epilepsy consistent with the ILAE's educational mission. Subcortical laminar heterotopia, also known as subcortical band heterotopia (SBH) or "double cortex," is an intriguing and rare congenital malformation of cortical development. SBH lesions are part of a continuum best designated as agyria-pachygyria-band-spectrum. The malformation is associated with epilepsy that is often refractory, as well as variable degrees of developmental delay...
February 14, 2024: Epileptic Disorders: International Epilepsy Journal with Videotape
https://read.qxmd.com/read/38345348/mapping-hippocampal-and-thalamic-atrophy-in-epilepsy-a-7-t-magnetic-resonance-imaging-study
#24
JOURNAL ARTICLE
Alfredo Lucas, Sofia Mouchtaris, Ashley Tranquille, Nishant Sinha, Ryan Gallagher, Marissa Mojena, Joel M Stein, Sandhitsu Das, Kathryn A Davis
OBJECTIVE: Epilepsy patients are often grouped together by clinical variables. Quantitative neuroimaging metrics can provide a data-driven alternative for grouping of patients. In this work, we leverage ultra-high-field 7-T structural magnetic resonance imaging (MRI) to characterize volumetric atrophy patterns across hippocampal subfields and thalamic nuclei in drug-resistant focal epilepsy. METHODS: Forty-two drug-resistant epilepsy patients and 13 controls with 7-T structural neuroimaging were included in this study...
February 12, 2024: Epilepsia
https://read.qxmd.com/read/38342839/febrile-infection-related-epilepsy-syndrome-with-claustrum-lesion-an-underdiagnosed-inflammatory-encephalopathy
#25
JOURNAL ARTICLE
Lin Bai, Weiying Di, Zucai Xu, Bin Liu, Nan Lin, Siyuan Fan, Haitao Ren, Qiang Lu, Jiawei Wang, Hongzhi Guan
OBJECTIVE: To summarize the clinical characteristics and prognosis of febrile infection-related epilepsy syndrome with claustrum lesions (FIRES-C). METHOD: Clinical data of FIRES-C patients were collected retrospectively. The study reviewed and analyzed their clinical manifestations, treatment strategies, and prognosis. RESULT: Twenty patients were enrolled, including 13 females and 7 males, with a median onset age of 20.5 years. All patients developed seizures after fever, with a median interval of 5 days...
February 12, 2024: Neurological Sciences
https://read.qxmd.com/read/38331678/motor-cognitive-and-behavioural-outcomes-after-neonatal-hypoxic-ischaemic-encephalopathy
#26
JOURNAL ARTICLE
María Montesclaros Hortigüela, Miriam Martínez-Biarge, David Conejo, Cristina Vega-Del-Val, Juan Arnaez
INTRODUCTION: The current neurodevelopmental status of patients with neonatal hypoxic-ischaemic encephalopathy (HIE) in Spain is unknown. Recent European studies highlight a shift of severe pathology towards mild motor disorders and emotional problems. The aim of this study was to analyse neurodevelopmental outcomes in a cohort of neonates with HIE at age 3 years. PATIENTS AND METHOD: Multicentre observational study of neonates born at 35 or more weeks of gestation with moderate to severe HIE in 2011-2013 in 12 hospitals in a large Spanish region (91 217 m2 ), with the recruitment extended through 2017 in the coordinating hospital...
February 7, 2024: Anales de pediatría
https://read.qxmd.com/read/38325385/autoimmune-encephalitis-in-a-resource-limited-public-health-setting-a-case-series-analysis
#27
JOURNAL ARTICLE
Matheus Bernardon Morillos, Wyllians Vendramini Borelli, Giovani Noll, Cristian Daniel Piccini, Martim Bravo Leite, Alessandro Finkelsztejn, Marino Muxfeldt Bianchin, Raphael Machado Castilhos, Carolina Machado Torres
BACKGROUND:  Autoimmune encephalitis (AE) consists of a group of acquired diseases that affect the central nervous system. A myriad of phenotypes may be present at the onset. Due to the heterogeneity of clinical presentations, it is difficult to achieve uniformity for the diagnostic and therapeutic processes and follow-up strategies. OBJECTIVE:  To describe a series of patients diagnosed with AE in a resource-limited public hospital in southern Brazil and to analyze therapeutics and outcomes...
February 2024: Arquivos de Neuro-psiquiatria
https://read.qxmd.com/read/38314605/structural-and-functional-abnormalities-in-first-episode-drug-na%C3%A3-ve-pediatric-idiopathic-generalized-epilepsy
#28
JOURNAL ARTICLE
Dingmei Deng, Hui Sun, Yuting Wang, Xin Guo, Yizhi Yuan, Jiaojian Wang, Lihua Qiu
The aim of this study was to investigate brain structure and corresponding static and dynamic functional connectivity (sFC & dFC) abnormalities in untreated, first-episode pediatric idiopathic generalized epilepsy (IGE), with the goal of better understanding the underlying pathological mechanisms of IGE. Thirty-one children with IGE and 31 age-matched healthy controls (HC) were recruited. Structural magnetic resonance imaging (sMRI) data were acquired, and voxel-based morphometry (VBM) analysis were performed to reveal abnormal gray matter volume (GMV)...
January 31, 2024: Cerebral Cortex
https://read.qxmd.com/read/38311614/combining-opm-and-lesion-mapping-data-for-epilepsy-surgery-planning-a-simulation-study
#29
JOURNAL ARTICLE
Stephanie Mellor, Ryan C Timms, George C O'Neill, Tim M Tierney, Meaghan E Spedden, Matthew J Brookes, Konrad Wagstyl, Gareth R Barnes
When planning for epilepsy surgery, multiple potential sites for resection may be identified through anatomical imaging. Magnetoencephalography (MEG) using optically pumped sensors (OP-MEG) is a non-invasive functional neuroimaging technique which could be used to help identify the epileptogenic zone from these candidate regions. Here we test the utility of a-priori information from anatomical imaging for differentiating potential lesion sites with OP-MEG. We investigate a number of scenarios: whether to use rigid or flexible sensor arrays, with or without a-priori source information and with or without source modelling errors...
February 4, 2024: Scientific Reports
https://read.qxmd.com/read/38306606/guidelines-for-specialized-epilepsy-centers-executive-summary-of-the-report-of-the-national-association-of-epilepsy-centers-guideline-panel
#30
JOURNAL ARTICLE
Fred A Lado, Stephanie M Ahrens, Ellen Riker, Carrie R Muh, R Mark Richardson, Johanna Gray, Barbara Small, Sandra Z Lewis, Thomas J Schofield, Dave F Clarke, Jennifer L Hopp, Roland R Lee, Jay A Salpekar, Susan T Arnold
The National Association of Epilepsy Centers first published the guidelines for epilepsy centers in 1990, which were last updated in 2010. Since that update, epilepsy care and the science of guideline development have advanced significantly, including the importance of incorporating a diversity of stakeholder perspectives such as those of patients and their caregivers. Currently, despite extensive published data examining the efficacy of treatments and diagnostic testing for epilepsy, there remain significant gaps in data identifying the essential services needed for a comprehensive epilepsy center and the optimal manner for their delivery...
February 2024: Neurology
https://read.qxmd.com/read/38296113/altered-static-and-dynamic-functional-connectivity-of-the-default-mode-network-across-epilepsy-subtypes-in-children-a-resting-state-fmri-study
#31
JOURNAL ARTICLE
Yongxin Li, Yun Ran, Maohua Yao, Qian Chen
BACKGROUND: Epilepsy is a chronic neurologic disorder characterized by abnormal functioning of brain networks, making it a complex research topic. Recent advancements in neuroimaging technology offer an effective approach to unraveling the intricacies of the human brain. Within different types of epilepsy, there is growing recognition regarding ongoing changes in the default mode network (DMN). However, little is known about the shared and distinct alterations of static functional connectivity (sFC) and dynamic functional connectivity (dFC) in DMN among epileptic subtypes, especially in children with epilepsy...
January 29, 2024: Neurobiology of Disease
https://read.qxmd.com/read/38283075/magnetic-resonance-imaging-findings-and-their-association-with-electroencephalographic-data-in-children-with-epilepsy-at-tertiary-care-hospital-in-mogadishu-somalia
#32
JOURNAL ARTICLE
Abdinasir Mohamed Elmi, Abdiwahid Ahmed Ibrahim, Mohamed Sheikh Hassan, Faisal Abdi Osoble Osman, Cihan Çelik, Abdikadir Mohamed Dirie, Ismail Gedi Ibrahim
INTRODUCTION: Epilepsy is a neurological disorder characterized by abnormal, fast, synchronous neuronal discharge from the cerebral cortex. This abnormal excitation of the brain is usually short and self-limiting and can last anywhere from a few seconds to a few minutes. Neuroimaging and electroencephalography (EEG) are two widely used techniques to differentiate, verify, or exclude the diagnosis of epilepsy. The study aims to identify the frequency of EEG and MRI abnormalities in pediatric epilepsy and their correlations, aiming to improve diagnostic and treatment methods for these children...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38281393/structural-and-functional-changes-associated-with-functional-dissociative-seizures-a-review-of-the-literature
#33
REVIEW
Johann Hassan, Simon Taib, Antoine Yrondi
INTRODUCTION: The term 'functional/dissociative seizures (FDS)' refers to a paroxysmal, transient clinical manifestation that may include motor, sensory, vegetative, psychological and cognitive signs, similar to the manifestations observed in epileptic seizures. In recent years, there has been an increase of literature in the field of brain imaging research on functional neurological disorders and, more specifically, on FDS. However, most of the studies have been carried out on limited samples...
January 27, 2024: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/38279250/genetic-epilepsies-and-developmental-epileptic-encephalopathies-with-early-onset-a-multicenter-study
#34
JOURNAL ARTICLE
Benedetta Cavirani, Carlotta Spagnoli, Stefano Giuseppe Caraffi, Anna Cavalli, Carlo Alberto Cesaroni, Gianni Cutillo, Valentina De Giorgis, Daniele Frattini, Giulia Bruna Marchetti, Silvia Masnada, Angela Peron, Susanna Rizzi, Costanza Varesio, Luigina Spaccini, Aglaia Vignoli, Maria Paola Canevini, Pierangelo Veggiotti, Livia Garavelli, Carlo Fusco
The genetic causes of epilepsies and developmental and epileptic encephalopathies (DEE) with onset in early childhood are increasingly recognized. Their outcomes vary from benign to severe disability. In this paper, we wished to retrospectively review the clinical, genetic, EEG, neuroimaging, and outcome data of patients experiencing the onset of epilepsy in the first three years of life, diagnosed and followed up in four Italian epilepsy centres (Epilepsy Centre of San Paolo University Hospital in Milan, Child Neurology and Psychiatry Unit of AUSL-IRCCS di Reggio Emilia, Pediatric Neurology Unit of Vittore Buzzi Children's Hospital, Milan, and Child Neurology and Psychiatry Unit, IRCCS Mondino Foundation, Pavia)...
January 19, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38274784/seizure-event-detection-using-intravital-two-photon-calcium-imaging-data
#35
JOURNAL ARTICLE
Matthew A Stern, Eric R Cole, Robert E Gross, Ken Berglund
SIGNIFICANCE: Intravital cellular calcium imaging has emerged as a powerful tool to investigate how different types of neurons interact at the microcircuit level to produce seizure activity, with newfound potential to understand epilepsy. Although many methods exist to measure seizure-related activity in traditional electrophysiology, few yet exist for calcium imaging. AIM: To demonstrate an automated algorithmic framework to detect seizure-related events using calcium imaging-including the detection of pre-ictal spike events, propagation of the seizure wavefront, and terminal spreading waves for both population-level activity and that of individual cells...
April 2024: Neurophotonics
https://read.qxmd.com/read/38268622/neurocysticercosis-a-neglected-but-preventable-cause-of-seizure-in-adults
#36
Prosper Adjei, Vida Obese, Richard Tang, Kingsley Owusu Manu, Yaw Owusu Afriyie Boateng, Eunice Ansomah Donkor
Neurocysticercosis is an infection of the central nervous system caused by the larval stage of Taenia solium . Although endemic in sub-Saharan Africa, it is neglected but remains a significant cause of preventable seizure in adults. Its diagnosis is challenging and is frequently missed due to its variable clinical manifestations and lack of diagnostic facilities in most areas of sub-Saharan Africa. This report discusses two cases of parenchymal neurocysticercosis in Ghanaians who presented to the emergency unit of a District Hospital with adult-onset seizures...
January 2024: Clinical Case Reports
https://read.qxmd.com/read/38261030/utility-of-genetic-testing-in-the-pre-surgical-evaluation-of-children-with-drug-resistant-epilepsy
#37
JOURNAL ARTICLE
Sarah Alsubhi, Saoussen Berrahmoune, Roy W R Dudley, David Dufresne, Elisabeth Simard Tremblay, Myriam Srour, Kenneth A Myers
We evaluated the utility of genetic testing in the pre-surgical evaluation of pediatric patients with drug-resistant focal epilepsy. This single-center retrospective study reviewed the charts of all pediatric patients referred for epilepsy surgery evaluation over a 5-year period. We extracted and analyzed results of genetic testing as well as clinical, EEG, and neuroimaging data. Of 125 patients referred for epilepsy surgical evaluation, 86 (69%) had some form of genetic testing. Of these, 18 (21%) had a pathogenic or likely pathogenic variant identified...
January 23, 2024: Journal of Neurology
https://read.qxmd.com/read/38258486/multimodal-non-invasive-evaluation-in-mri-negative-epilepsy-patients
#38
JOURNAL ARTICLE
Wei Wang, Qian Huang, Qilin Zhou, Jiaqi Han, Xiating Zhang, Liping Li, Yicong Lin, Yuping Wang
Presurgical evaluation is still challenging for MRI-negative epilepsy patients. As non-invasive modalities are the easiest acceptable and economic methods in determining the epileptogenic zone, we analyzed the localization value of common non-invasive methods in MRI-negative epilepsy patients. In this study, we included epilepsy patients undergoing presurgical evaluation with presurgical negative MRI. MRI post-processing was performed using a Morphometric Analysis Program (MAP) on T1-weighted volumetric MRI...
January 23, 2024: Epilepsia Open
https://read.qxmd.com/read/38251334/calcified-neurocysticercosis-demographic-clinical-and-radiological-characteristics-of-a-large-hospital-based-patient-cohort
#39
JOURNAL ARTICLE
Javier A Bustos, Gianfranco Arroyo, Oscar H Del Brutto, Isidro Gonzales, Herbert Saavedra, Carolina Guzman, Sofia S Sanchez-Boluarte, Kiran T Thakur, Christina Coyle, Seth E O'Neal, Hector H Garcia
Neurocysticercosis (NCC), the infection of the central nervous system caused by Taenia solium larvae (cysticerci), is a major cause of acquired epilepsy worldwide. Calcification in NCC is the most common neuroimaging finding among individuals with epilepsy in T. solium -endemic areas. We describe the demographic, clinical, and radiological profiles of a large hospital cohort of patients with calcified NCC in Peru (during the period 2012-2022) and compared profiles between patients with and without a previous known diagnosis of viable infection...
December 27, 2023: Pathogens
https://read.qxmd.com/read/38250750/application-value-of-multimodal-mri-combined-with-pet-metabolic-parameters-in-temporal-lobe-epilepsy-with-dual-pathology
#40
JOURNAL ARTICLE
Yu Kong, Nan Cheng, Feng-Juan Qiu, Lei Yao, Ming Gao, An-Qiang Chen, Qing-Xia Kong, Gu-Qing Zhang
OBJECTIVES: To investigate the application value of multimodal MRI combined with PET metabolic parameters in detecting temporal lobe epilepsy (TLE) with dual pathology (DP) and the prediction effect of post-surgical outcomes in these patients. METHODS: We retrospectively reviewed 50 patients with TLE-DP who underwent surgery at our hospital between January 2016 and December 2021 and collected the demographics, clinical characteristics, video-electroencephalography (v-EEG), neuroimaging, and surgical data...
December 2023: European Journal of Radiology
keyword
keyword
100913
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.