keyword
MENU ▼
Read by QxMD icon Read
search

Mri and epilepsy

keyword
https://www.readbyqxmd.com/read/28098941/posterior-cortex-epilepsy-surgery-in-childhood-and-adolescence-predictors-of-long-term-seizure-outcome
#1
Georgia Ramantani, Angeliki Stathi, Armin Brandt, Karl Strobl, Susanne Schubert-Bast, Gert Wiegand, Rudolf Korinthenberg, Vera van Velthoven, Josef Zentner, Andreas Schulze-Bonhage, Thomas Bast
OBJECTIVE: We aimed to investigate the long-term seizure outcome of children and adolescents who were undergoing epilepsy surgery in the parietooccipital cortex and determine their predictive factors. METHODS: We retrospectively analyzed the data of 50 consecutive patients aged 11.1 (mean) ± 5.1 (standard deviation) years at surgery. All patients but one had a magnetic resonance imaging (MRI)-visible lesion. Resections were parietal in 40%, occipital in 32%, and parietooccipital in 28% cases; 24% patients additionally underwent a resection of the posterior border of the temporal lobe...
January 18, 2017: Epilepsia
https://www.readbyqxmd.com/read/28098938/towards-prognostic-biomarkers-from-bold-fluctuations-to-differentiate-a-first-epileptic-seizure-from-new-onset-epilepsy
#2
Lalit Gupta, Rick Janssens, Mariëlle C G Vlooswijk, Rob P W Rouhl, Anton de Louw, Albert P Aldenkamp, Shrutin Ulman, René M H Besseling, Paul A M Hofman, Vivianne H van Kranen-Mastenbroek, Danny M Hilkman, Jacobus F A Jansen, Walter H Backes
OBJECTIVE: The diagnosis of epilepsy cannot be reliably made prior to a patient's second seizure in most cases. Therefore, adequate diagnostic tools are needed to differentiate subjects with a first seizure from those with a seizure preceding the onset of epilepsy. The objective was to explore spontaneous blood oxygen level-dependent (BOLD) fluctuations in subjects with a first-ever seizure and patients with new-onset epilepsy (NOE), and to find characteristic biomarkers for seizure recurrence after the first seizure...
January 18, 2017: Epilepsia
https://www.readbyqxmd.com/read/28096104/recent-developments-in-the-surgical-management-of-paediatric-epilepsy
#3
REVIEW
Vijay M Ravindra, Matthew T Sweney, Robert J Bollo
Among the 1% of children affected by epilepsy, failure of pharmacological therapy and early age of seizure onset can lead to worse long-term cognitive outcomes, mental health disorders and impaired functional status. Surgical management often improves functional and cognitive outcomes in children with medically refractory epilepsy, especially when seizure remission is achieved. However, surgery remains underused in children with drug-resistant epilepsy, creating a large treatment gap. Several recent innovations have led to considerable improvement in surgical technique, including the recent development of minimally invasive diagnostic and therapeutic techniques such as stereotactic EEG, transcranial magnetic stimulation, MRI-guided laser ablation, as well as novel paradigms of neurostimulation...
January 17, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28092848/the-initial-use-of-arterial-spin-labeling-perfusion-and-diffusion-weighted-magnetic-resonance-images-in-the-diagnosis-of-nonconvulsive-partial-status-epileptics
#4
Takafumi Shimogawa, Takato Morioka, Tetsuro Sayama, Sei Haga, Yuka Kanazawa, Kei Murao, Shuji Arakawa, Ayumi Sakata, Koji Iihara
BACKGROUND: In the diagnosis of nonconvulsive status epilepticus (NCSE), capture of ongoing ictal electroencephalographic (EEG) findings is the gold standard; however, this is practically difficult without continuous EEG monitoring facilities. Magnetic resonance imaging (MRI), including diffusion-weighted imaging (DWI) and perfusion MRI with arterial spin labeling (ASL), have been applied mainly in emergency situations. Recent reports have described that ictal MRI findings, including ictal hyperperfusion on ASL and cortical hyperintensity of cytotoxic edema on DWI, can be obtained from epileptically activated cortex...
December 21, 2016: Epilepsy Research
https://www.readbyqxmd.com/read/28087827/neuropsychological-outcome-following-frontal-lobectomy-for-pharmacoresistant-epilepsy-in-adults
#5
Robyn M Busch, Darlene P Floden, Lisa Ferguson, Shamseldeen Mahmoud, Audrina Mullane, Stephen Jones, Lara Jehi, William Bingaman, Imad M Najm
OBJECTIVE: This retrospective cohort study characterized cognitive and motor outcomes in a large sample of adults who underwent frontal lobe resections for treatment of pharmacoresistant epilepsy. METHODS: Ninety patients who underwent unilateral frontal lobe resection for epilepsy (42 language-dominant hemisphere/48 nondominant hemisphere) between 1989 and 2014 completed comprehensive preoperative and postoperative neuropsychological evaluations that included measures of verbal and nonverbal intellectual functioning, attention/working memory, processing speed, language, executive functioning, verbal and visual memory, and motor functioning...
January 13, 2017: Neurology
https://www.readbyqxmd.com/read/28087826/comparison-of-brain-mri-findings-with-language-and-motor-function-in-the-dystroglycanopathies
#6
Brianna N Brun, Shelley R H Mockler, Katie M Laubscher, Carrie M Stephan, Anne M Wallace, Julia A Collison, M Bridget Zimmerman, William B Dobyns, Katherine D Mathews
OBJECTIVE: To describe the spectrum of brain MRI findings in a cohort of individuals with dystroglycanopathies (DGs) and relate MRI results to function. METHODS: All available brain MRIs done for clinical indications on individuals enrolled in a DG natural history study (NCT00313677) were reviewed. Reports were reviewed when MRI was not available. MRIs were categorized as follows: (1) cortical, brainstem, and cerebellar malformations; (2) cortical and cerebellar malformations; or (3) normal...
January 13, 2017: Neurology
https://www.readbyqxmd.com/read/28087439/cerebrovascular-heterogeneity-and-neuronal-excitability
#7
REVIEW
Laura Librizzi, Marco de Curtis, Damir Janigro, Leonie Runtz, Frederic deBock, Emmanuel L Barbier, Nicola Marchi
The cerebral vasculature is a complex tridimensional network of arterial and venous vessels which are anatomically in proximity of and functionally coupled to neurons. Depending on the cellular composition of the vascular wall and its anatomical arrangement, cerebral vessels control regional blood flow, define interstitial homeostasis or cerebrospinal fluid circulation and influence immune cell patrolling. Pathological deviations from these functions promote or are a consequence of brain diseases, directly impacting neuronal firing...
January 10, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28079471/pre-implant-modeling-of-depth-lead-placement-in-white-matter-for-maximizing-the-extent-of-cortical-activation-during-direct-neurostimulation-therapy
#8
Leopoldo Cendejas Zaragoza, Richard W Byrne, Marvin A Rossi
INTRODUCTION: The objective of this work was to predict preoperatively the maximum extent to which direct stimulation therapy can propagate through an epileptic circuit for stabilizing refractory focal-onset epilepsy. A pre-surgical workflow is presented which comprises a computationally intensive process for calculating the volume of cortical activation (VOCA) surrounding cylindrical depth contacts virtually placed in white matter. The process employs an activation function (AF) derived from cable modeling of an axon...
January 12, 2017: Neurological Research
https://www.readbyqxmd.com/read/28078313/unilobar-surgery-for-symptomatic-epileptic-spasms
#9
Carmen Barba, Roberto Mai, Laura Grisotto, Francesca Gozzo, Simona Pellacani, Laura Tassi, Stefano Francione, Flavio Giordano, Francesco Cardinale, Renzo Guerrini
OBJECTIVE: To assess factors associated with favorable seizure outcome after surgery for symptomatic epileptic spasms and improve knowledge on pathophysiology of this seizure type. METHODS: Inclusion criteria were: (1) age between 6 months and 15 years at surgery; (2) active epileptic spasms; (3) follow-up after surgery >1 year. RESULTS: We retrospectively studied 80 children (aged 1.3 ± 2 years at seizure onset; 5.8 ± 4 years at surgery, 11...
January 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28077892/accuracy-of-conventional-diagnostic-methods-for-identifying-structural-changes-in-patients-with-focal-epilepsy
#10
Nazim Dakaj, Jera Kruja, Fisnik Jashari, Dren Boshnjaku, Nexhat Shatri, Kamber Zeqiraj
BACKGROUND: Epilepsy is a neurological disorder characterized by abnormal firing of nerve impulses in the brain. AIM: This study aims to investigate the frequency of appearance of pathological changes in conventional examination methods (electroencephalography-EEG, brain computerized tomography -CT or brain magnetic resonance imaging - MRI) in patients with epilepsy, and relationship between clinical manifestations and localization of changes in CT or MRI. METHODS: In this study we have included 110 patients with focal epilepsy who fulfilled the inclusion criteria out of 557 initially diagnosed patients...
October 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28077494/practice-guideline-summary-use-of-fmri-in-the-presurgical-evaluation-of-patients-with-epilepsy-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology
#11
Jerzy P Szaflarski, David Gloss, Jeffrey R Binder, William D Gaillard, Alexandra J Golby, Scott K Holland, Jeffrey Ojemann, David C Spencer, Sara J Swanson, Jacqueline A French, William H Theodore
OBJECTIVE: To assess the diagnostic accuracy and prognostic value of functional MRI (fMRI) in determining lateralization and predicting postsurgical language and memory outcomes. METHODS: An 11-member panel evaluated and rated available evidence according to the 2004 American Academy of Neurology process. At least 2 panelists reviewed the full text of 172 articles and selected 37 for data extraction. Case reports, reports with <15 cases, meta-analyses, and editorials were excluded...
January 11, 2017: Neurology
https://www.readbyqxmd.com/read/28074282/unique-findings-of-subependymal-giant-cell-astrocytoma-within-cortical-tubers-in-patients-with-tuberous-sclerosis-complex-a-histopathological-evaluation
#12
Joel S Katz, Hyman Frankel, Tracy Ma, David Zagzag, Benjamin Liechty, Bruria Ben Zeev, Michal Tzadok, Orrin Devinsky, Howard L Weiner, Jonathan Roth
INTRODUCTION: Tuberous sclerosis is associated with three central nervous system pathologies: cortical/subcortical tubers, subependymal nodules (SENs), and subependymal giant cell astrocytomas (SEGAs). Tubers are associated with epilepsy, which is often medication-resistant and often leads to resective surgery. Recently, mammalian target of rapamycin inhibitors (mTORi) have been shown to be effective reducing seizure burden in some patients with tuberous sclerosis complex (TSC)-related refractory epilepsy...
January 10, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28073096/high-density-scalp-eeg-in-frontal-lobe-epilepsy
#13
Anteneh M Feyissa, Jeffrey W Britton, Jamie Van Gompel, Terrance L Lagerlund, Elson So, Lilly C Wong-Kisiel, Gregory C Cascino, Benjamin H Brinkman, Cindy L Nelson, Robert Watson, Gregory A Worrell
PURPOSE: Localization of seizures in frontal lobe epilepsy using the 10-20 system scalp EEG is often challenging because neocortical seizure can spread rapidly, significant muscle artifact, and the suboptimal spatial resolution for seizure generators involving mesial frontal lobe cortex. Our aim in this study was to determine the value of visual interpretation of 76 channel high density EEG (hdEEG) monitoring (10-10 system) in patients with suspected frontal lobe epilepsy, and to evaluate concordance with MRI, subtraction ictal SPECT co-registered to MRI (SISCOM), conventional EEG, and intracranial EEG (iEEG)...
January 2, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28067149/navigation-assisted-trans-inferotemporal-cortex-selective-amygdalohippocampectomy-for-mesial-temporal-lobe-epilepsy-preserving-the-temporal-stem
#14
Haruhiko Kishima, Amami Kato, Satoru Oshino, Naoki Tani, Tomoyuki Maruo, Hui Ming Khoo, Takufumi Yanagisawa, Kotaro Edakawa, Maki Kobayashi, Masataka Tanaka, Koichi Hosomi, Masayuki Hirata, Toshiki Yoshimine
OBJECTIVE: Selective amygdalohippocampectomy (SAH) can be used to obtain satisfactory seizure control in patients with mesial temporal lobe epilepsy (MTLE). Several SAH procedures have been reported to achieve satisfactory outcomes for seizure control, but none yield fully satisfactory outcomes for memory function. We hypothesized that preserving the temporal stem might play an important role. To preserve the temporal stem, we developed a minimally invasive surgical procedure, 'neuronavigation-assisted trans-inferotemporal cortex SAH' (TITC-SAH)...
January 9, 2017: Neurological Research
https://www.readbyqxmd.com/read/28063856/effectiveness-of-deferoxamine-on-ferric-chloride-induced-epilepsy-in-rats
#15
Xiang Zou, Shize Jiang, Zehan Wu, Yimin Shi, Shengyong Cai, Renqing Zhu, Liang Chen
Iron overload has been regarded as a common cause for refractory epilepsies in patients after hemorrhagic strokes. This study is to examine the potential epilepsy control effect of deferoxamine (DFO), an iron chelator, on a ferric chloride-induced epilepsy rat model. Twenty four rats were divided into 4 groups: group I is blank control group, group II is sham group with intracortical injection of saline, group III is epilepsy group with intracortical injection of iron and saline treatment, group IV is treatment group with intracortical injection of iron and DFO treatment...
January 4, 2017: Brain Research
https://www.readbyqxmd.com/read/28054328/magnetoencephalography-and-new-imaging-modalities-in-epilepsy
#16
REVIEW
Jessica Falco-Walter, Christian Owen, Mishu Sharma, Christopher Reggi, Mandy Yu, Travis R Stoub, Michael A Stein
The success of epilepsy surgery is highly dependent on correctly identifying the entire epileptogenic region. Current state-of-the-art for localizing the extent of surgically amenable areas involves combining high resolution three-dimensional magnetic resonance imaging (MRI) with electroencephalography (EEG) and magnetoencephalography (MEG) source modeling of interictal epileptiform activity. Coupling these techniques with newer quantitative structural MRI techniques, such as cortical thickness measurements, however, may improve the extent to which the abnormal epileptogenic region can be visualized...
January 4, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/28054170/risk-factors-for-unprovoked-epileptic-seizures-in-multiple-sclerosis-a-systematic-review-and-meta-analysis
#17
REVIEW
Sara Gasparini, Edoardo Ferlazzo, Michele Ascoli, Chiara Sueri, Vittoria Cianci, Concetta Russo, Laura Rosa Pisani, Pasquale Striano, Maurizio Elia, Ettore Beghi, Carmela Colica, Umberto Aguglia
The role of different factors in influencing the risk of seizures during multiple sclerosis (MS) is not known. To perform a systematic review and meta-analysis of risk factors for epilepsy during MS. Pubmed, Google scholar, and Scopus databases were searched. Articles published in English (1986-2016) were included. Nine studies were included (3 retrospective cohort and 6 case-control) enrolling 2845 MS patients (217 with epilepsy; 7.6%). MS patients with epilepsy had a younger age at onset compared to MS patients without seizures (difference in means = -5...
January 4, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28053860/dyke-davidoff-masson-syndrome-in-a-nigerian
#18
Philip B Adebayo, Amnat Bakare, Modupe M Bello, Opeyemi D Olaewe, Kolawole W Wahab
Dyke-Davidoff-Masson syndrome (DDMS) is a rare, but important cause of drug-resistant seizures. Dyke-Davidoff-Masson syndrome is a constellation of clinical features that consists of hemiparesis, seizure, facial asymmetry, and intellectual disability with distinct neuroimaging features. A 27-year-old lady presented to us with drug-resistant epilepsy, hemiparesis, and intellectual disability that necessitated her withdrawal from school. Her brain magnetic resonance imaging (MRI) showed cerebral hemiatrophy, calvarial thickening, and hyperpneumatization of the frontal sinuses consistent with DDMS...
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/28048162/su-f-r-08-can-normalization-of-brain-mri-texture-features-reduce-scanner-dependent-effects-in-unsupervised-machine-learning
#19
K Ogden, T Bradford, L Cussen, R O'Dwyer
PURPOSE: To reduce differences in features calculated from MRI brain scans acquired at different field strengths with or without Gadolinium contrast. METHODS: Brain scans were processed for 111 epilepsy patients to extract hippocampus and thalamus features. Scans were acquired on 1.5 T scanners with Gadolinium contrast (group A), 1.5T scanners without Gd (group B), and 3.0 T scanners without Gd (group C). A total of 72 features were extracted. Features were extracted from original scans and from scans where the image pixel values were rescaled to the mean of the hippocampi and thalami values...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045733/pet-mri-coregistration-in-intractable-epilepsy-and-gray-matter-heterotopia
#20
Nikhil Seniaray, Anuj Jain
A 25-year-old woman with intractable seizures underwent FDG PET/MRI for seizure focus localization. MRI demonstrated bilateral carpetlike nodular subependymal gray matter and asymmetrical focal dilatation in the right temporal horn. PET/MRI showed increased FDG within subependymal gray matter with significant hypometabolism in right anterior temporal lobe. EEG and ictal semiology confirmed the right temporal seizure origin. This case highlights the importance of identification of gray matter heterotopia on FDG PET/MRI...
December 30, 2016: Clinical Nuclear Medicine
keyword
keyword
100910
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"