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https://www.readbyqxmd.com/read/28419504/sensory-and-rheological-characteristics-of-thickened-liquids-differing-concentrations-of-a-xanthan-gum-based-thickener
#1
Hyeri Kim, Han-Im Hwang, Ki-Won Song, Jeehyun Lee
The objectives of this study were to develop and compare sensory characteristics of beverages and soups thickened with different concentrations of a xanthan gum-based thickener, and to examine, using rheological measurement, whether the viscosity of the thickened liquids conformed to the recommendations of the National Dysphagia Diet Task Force. Beverages tested included water, plum juice, apple juice, orange juice, milk, soymilk, and Yakult. The thickening agent was added to samples at concentrations of 1%, 2%, or 3%...
April 17, 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28408800/rutin-protects-against-neuronal-damage-in-vitro-and-ameliorates-doxorubicin-induced-memory-deficits-in-vivo-in-wistar-rats
#2
Grandhi Venkata Ramalingayya, Sri Pragnya Cheruku, Pawan G Nayak, Anoop Kishore, Rekha Shenoy, Chamallamudi Mallikarjuna Rao, Nandakumar Krishnadas
Doxorubicin (DOX) is the most widely used broad-spectrum anticancer agent, either alone or in combination, for most cancers including breast cancer. Long-term use of chemotherapeutic agents to treat breast cancer patients results in cognitive complications with a negative impact on survivors' quality of life. The study objective was to evaluate rutin (RUT) for its neuroprotective effect against DOX in human neuroblastoma (IMR32) cells in vitro and study its potential to ameliorate DOX-induced cognitive dysfunction in Wistar rats...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28392783/agro-industrial-wastes-for-production-of-biosurfactant-by-bacillus-subtilis-anr-88-and-its-application-in-synthesis-of-silver-and-gold-nanoparticles
#3
Ashwini N Rane, Vishakha V Baikar, D V Ravi Kumar, Rajendra L Deopurkar
Biosurfactants, surface-active amphiphilic compounds, despite having a wide range of applications, have a high cost of production, which severely restricts their use. For cheaper production of biosurfactant, we investigated the potential of the indigenously isolated biosurfactant producing organism, Bacillus subtilis ANR 88, to grow on different cheap carbon sources (molasses, whey, and extracts of potato peels, orange peels, banana peels, and bagasse). We found that, B. subtilis ANR 88 used significant amounts of total sugar to produce cell biomass and biosurfactant...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28392162/oncolytic-virotherapy-a-contest-between-apples-and-oranges
#4
REVIEW
Stephen J Russell, Kah-Whye Peng
Viruses can be engineered or adapted for selective propagation in neoplastic tissues and further modified for therapeutic transgene expression to enhance their antitumor potency and druggability. Oncolytic viruses (OVs) can be administered locally or intravenously and spread to a variable degree at sites of tumor growth. OV-infected tumor cells die in situ, releasing viral and tumor antigens that are phagocytosed by macrophages, transported to regional lymph nodes, and presented to antigen-reactive T cells, which proliferate before dispersing to kill uninfected tumor cells at distant sites...
April 6, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/28378916/cdse-and-cdse-cds-core-shell-qds-new-approach-for-synthesis-investigating-optical-properties-and-application-in-pollutant-degradation
#5
S Abbasi, M Molaei, M Karimipour
In this work, CdSe quantum dots (QDs) were synthesized by a simple and rapid microwave activated approach using CdSO4 , Na2 SeO3 as precursors and thioglycolic acid (TGA) as capping agent molecule. A novel photochemical approach was introduced for the growth of CdS QDs and this approach was used to grow a CdS shell around CdSe cores for the formation of a CdSe/CdS core-shell structure. The core-shells were structurally verified using X-ray diffraction, transmission electron microscopy and FTIR (Fourier-transform infrared (FTIR)) spectroscopy...
April 5, 2017: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/28343961/protein-depletion-using-the-arabinose-promoter-in-xanthomonas-citri-subsp-citri
#6
Lilian A Lacerda, Lucia B Cavalca, Paula M M Martins, José S Govone, Maurício Bacci, Henrique Ferreira
Xanthomonas citri subsp. citri (X. citri) is a plant pathogen and the etiological agent of citrus canker, a severe disease that affects all the commercially important citrus varieties, and has worldwide distribution. Citrus canker cannot be healed, and the best method known to control the spread of X. citri in the orchards is the eradication of symptomatic and asymptomatic plants in the field. However, in the state of São Paulo, Brazil, the main orange producing area in the world, control is evolving to an integrated management system (IMS) in which growers have to use less susceptible plants, windshields to prevent bacterial spread out and sprays of cupric bactericidal formulations...
March 24, 2017: Plasmid
https://www.readbyqxmd.com/read/28335646/synthesis-of-an-acridine-orange-sulfonamide-derivative-with-potent-carbonic-anhydrase-ix-inhibitory-action
#7
Marco Bragagni, Fabrizio Carta, Sameh M Osman, Zeid AlOthman, Claudiu T Supuran
Acridine orange (AO) a fluorescent cationic dye used for the management of human musculoskeletal sarcomas, due to its strong tumoricidal action and accumulation in the acidic environment typical of hypoxic tumors, was used for the preparation of a primary sulfonamide derivative. The rationale behind the drug design is the fact that hypoxic, acidic tumors overexpress carbonic anhydrase (CA, EC 4.2.1.1) isoforms, such as CA IX, which is involved in pH regulation, proliferation, cell migration and invasion, and this enzyme is strongly inhibited by primary sulfonamides...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28331912/effect-of-visible-range-electromagnetic-radiations-on-escherichia-coli
#8
Samina T Yousuf Azeemi, Saleem Farooq Shaukat, Khawaja Shamsuddin Azeemi, Idrees Khan, Khalid Mahmood, Farah Naz
BACKGROUND: Escherichia coli is the agent responsible for a range of clinical diseases. With emerging antimicrobial resistance, other treatment options including solar/photo-therapy are becoming increasingly common. Visible Range Radiation Therapy/Colour Therapy is an emerging technique in the field of energy/vibrational medicine that uses visible spectrum of Electromagnetic Radiations to cure different diseases. In this study, our goal was to understand the effect of Visible Range Electromagnetic Radiations on E...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28303540/exploiting-fruit-byproducts-for-eco-friendly-nanosynthesis-citrus%C3%A2-%C3%A3-%C3%A2-clementina-peel-extract-mediated-fabrication-of-silver-nanoparticles-with-high-efficacy-against-microbial-pathogens-and-rat-glial-tumor-c6-cells
#9
Rijuta Ganesh Saratale, Han-Seung Shin, Gopalakrishnan Kumar, Giovanni Benelli, Gajanan S Ghodake, Yuan Yuan Jiang, Dong Su Kim, Ganesh Dattatraya Saratale
Process byproducts from the fruit industry may represent a cheap and reliable source of green reducing agents to be used in current bio-nanosynthesis. This study reports the use of orange (Citrus × clementina) peel aqueous extract (OPE) for one-pot green synthesis of silver nanoparticles (AgNPs) with high effectiveness against various microbial pathogens as well as rat glial tumor C6 cells. The effects of various operational parameters on the synthesis of AgNPs were systematically investigated. The morphology, particle size, and properties of synthesized AgNPs were characterized using UV-visible spectroscopy, x-ray diffraction, x-ray photoelectron spectroscopy, field emission scanning electron microscopy, energy-dispersive x-ray spectroscopy, and Fourier transform infrared spectroscopy...
March 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28288376/facile-fabrication-of-dy2sn2o7-sno2-nanocomposites-as-an-effective-photocatalyst-for-degradation-and-removal-of-organic-contaminants
#10
Sahar Zinatloo-Ajabshir, Maryam Sadat Morassaei, Masoud Salavati-Niasari
Dy2Sn2O7-SnO2 nanocomposites were synthesized through a facile way utilizing propane-1,2-diol as novel polymerization agent and trimesic acid as new stabilization agent. Effects of different polymerization agents, calcination temperature and various stabilization agents on the size and shape of the Dy2Sn2O7-SnO2 nanocomposites were investigated. It was found that changing these synthesis factors has great role in controlling size and shape of Dy2Sn2O7-SnO2 nanocomposites. The as-produced Dy2Sn2O7-SnO2 nanostructures were analyzed using FT-IR, HRTEM, DR-UV-vis, EDS, XRD, and FESEM...
July 1, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28286111/spermatogenesis-disruption-by-dioxins-epigenetic-reprograming-and-windows-of-susceptibility
#11
REVIEW
J Richard Pilsner, Mikhail Parker, Oleg Sergeyev, Alexander Suvorov
Dioxins are a group of highly persistent chemicals that are generated as by-products of industrial and natural processes. Reduction in sperm counts is among the most sensitive endpoints of dioxin toxicity. The exact mechanism by which dioxins reduce sperm counts is not known. Recent data implicate the role of epididymal factors rather than disruption of spermatogenesis. Studies reviewed here demonstrate that dioxins induce the transfer of environmental conditions to the next generation via male germline following exposures during the window of epigenetic reprogramming of primordial germ cells...
March 7, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28263079/%C3%AF-expansive-heteroleptic-ruthenium-ii-complexes-as-reverse-saturable-absorbers-and-photosensitizers-for-photodynamic-therapy
#12
Li Wang, Huimin Yin, Mohammed A Jabed, Marc Hetu, Chengzhe Wang, Susan Monro, Xiaolin Zhu, Svetlana Kilina, Sherri A McFarland, Wenfang Sun
Five heteroleptic tris-diimine ruthenium(II) complexes [RuL(N^N)2](PF6)2 (where L is 3,8-di(benzothiazolylfluorenyl)-1,10-phenanthroline and N^N is 2,2'-bipyridine (bpy) (1), 1,10-phenanthroline (phen) (2), 1,4,8,9-tetraazatriphenylene (tatp) (3), dipyrido[3,2-a:2',3'-c]phenazine (dppz) (4), or benzo[i]dipyrido[3,2-a:2',3'-c]phenazine (dppn) (5), respectively) were synthesized. The influence of π-conjugation of the ancillary ligands (N^N) on the photophysical properties of the complexes was investigated by spectroscopic methods and simulated by density functional theory (DFT) and time-dependent DFT...
March 6, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28244942/effects-of-natural-phenolic-compound-carvacrol-on-the-human-gastric-adenocarcinoma-ags-cells-in-vitro
#13
Ayse Günes-Bayir, Huriye S Kiziltan, Abdurrahim Kocyigit, Eray M Güler, Ersin Karataş, Ali Toprak
Gastric cancer (GC) is the most common cause of morbidity and mortality because of cancer. Medicinal plants containing polyphenolic compounds have gained importance in anticancer treatment. In this context, carvacrol is a main component of many plants in the family Lamiaceae that are frequently used in folk medicine and a good candidate to investigate for GC treatment. The present study aimed to explore the cytotoxic, genotoxic, apoptotic, and reactive oxygen species (ROS)-generating effects of carvacrol on gastric adenocarcinoma in vitro...
June 2017: Anti-cancer Drugs
https://www.readbyqxmd.com/read/28235605/studies-of-dna-binding-properties-of-lafutidine-as-adjuvant-anticancer-agent-to-calf-thymus-dna-using-multi-spectroscopic-approaches-nmr-relaxation-data-molecular-docking-and-dynamical-simulation
#14
Hongqin Yang, Peixiao Tang, Bin Tang, Yanmei Huang, Jiawei He, Shanshan Li, Hui Li
The interactions between lafutidine (LAF) and calf thymus DNA (ctDNA) have been investigated both experimentally and theoretically. UV-vis absorption studies confirmed that LAF binds to ctDNA through non-covalent interactions. Fluorescence quenching and time-resolved fluorescence spectroscopy studies showed that the binding of LAF with ctDNA occurred through static quenching mechanism, resulting in the formation of a LAF-ctDNA complex. The binding constants (K) of the complex were found to be around 10(3)M(-1) via NMR relaxation rates and fluorescence data, and the calculated thermodynamic parameters indicated that hydrogen bonds and van der Waals forces played major roles in the binding of LAF to ctDNA...
June 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28221956/microbiological-quality-and-occurrence-of-nontuberculous-mycobacteria-in-fresh-squeezed-orange-juice-samples-purchased-from-street-vendors-in-mexico-city
#15
Jorge F Cerna-Cortes, Ana Laura Cortes-Cueto, Maria Rosalia Cano-Gaona, Nancy Leon-Montes, Addy C Helguera-Repetto, Sandra Rivera-Gutierrez, Laura P Salas-Rangel, Javier Castro-Rosas, Jorge A Gonzalez-Y-Merchand
Nontuberculous mycobacteria (NTM) are potentially pathogenic agents commonly found in a natural ecosystem. For this reason, food is considered another source of NTM transmission for humans. The aims of this study were to evaluate the microbiological quality and the occurrence of NTM in fresh-squeezed orange juice samples purchased from street vendors. All 102 samples analyzed were positive for aerobic mesophilic bacteria (AMB), with limits ranging from 1.8 to 6.2 log CFU/ml. A total of 55 (54%), 25 (25%), and 13 (13%) orange juice samples were positive for total coliforms (TC), fecal coliforms (FC), and Escherichia coli , respectively...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28219038/green-synthesis-characterization-and-catalytic-activity-of-silver-nanoparticles-using-cassia-auriculata-flower-extract-separated-fraction
#16
Karuppiah Muthu, Sethuraman Priya
Cassia auriculata L., the flower aqueous extract was fractionated by separating funnel using n-hexane (A1), chloroform (A2), ethyl acetate (A3) and triple distilled water (A4). The A4 fraction was concentrated and determined the presence of preliminary phytochemicals such as tannins, flavonoids, glycosides, carbohydrates and polyphenolic compounds. These phytochemical compounds acted as reducing as well as a stabilizing agent in the green synthesis of Ag NPs from aqueous silver ions. Initially, the colour change and UV-vis absorbance surface Plasmon resonance strong, wide band located at 435nm has confirmed the synthesis of Ag NPs...
February 12, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28208159/two-previously-unknown-phytophthora-species-associated-with-brown-rot-of-pomelo-citrus-grandis-fruits-in-vietnam
#17
Ivana Puglisi, Alessandro De Patrizio, Leonardo Schena, Thomas Jung, Maria Evoli, Antonella Pane, Nguyen Van Hoa, Mai Van Tri, Sandra Wright, Mauritz Ramstedt, Christer Olsson, Roberto Faedda, Gaetano Magnano di San Lio, Santa Olga Cacciola
Two distinct Phytophthora taxa were found to be associated with brown rot of pomelo (Citrus grandis), a new disease of this ancestral Citrus species, in the Vinh Long province, Mekong River Delta area, southern Vietnam. On the basis of morphological characters and using the ITS1-5.8S-ITS2 region of the rDNA and the cytochrome oxidase subunit 1 (COI) as barcode genes, one of the two taxa was provisionally named as Phytophthora sp. prodigiosa, being closely related to but distinct from P. insolita, a species in Phytophthora Clade 9, while the other one, was closely related to but distinct from the Clade 2 species P...
2017: PloS One
https://www.readbyqxmd.com/read/28198956/evaluating-pharmaceutical-waste-disposal-in-pediatric-units
#18
Maria Angélica Randoli de Almeida, Ana Maria Miranda Martins Wilson, Maria Angélica Sorgini Peterlini
OBJECTIVE: To verify the disposal of pharmaceutical waste performed in pediatric units. METHOD: A descriptive and observational study conducted in a university hospital. The convenience sample consisted of pharmaceuticals discarded during the study period. Handling and disposal during preparation and administration were observed. Data collection took place at pre-established times and was performed using a pre-validated instrument. RESULTS: 356 drugs disposals were identified (35...
November 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28194295/preparation-of-tio2-nanotubes-loaded-on-polyurethane-membrane-and-research-on-their-photocatalytic-properties
#19
Longli Lin, Qijun Wu, Xun Gong, Yu Zhang
To solve the problem of separation and recovery of photocatalyst in water, the modification of TiO2 was studied as well as its immobilization and photocatalytic properties. To improve surface properties, TiO2 nanotubes were synthesized by a hydrothermal method and silylated by silane coupling agents to introduce a certain functional group. Supported on polyurethane (PU) membrane, TiO2 nanotubes were prepared to produce immobilized PU/TiO2. Catalysts were characterized and identified by means of Fourier-transform infrared spectroscopy (FTIR), attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR), and scanning electron microscopy (SEM)...
2017: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/28179028/betanodavirus-like-particles-enter-host-cells-via-clathrin-mediated-endocytosis-in-a-cholesterol-ph-and-cytoskeleton-dependent-manner
#20
Runqing Huang, Guohua Zhu, Jing Zhang, Yuxiong Lai, Yu Xu, Jianguo He, Junfeng Xie
Betanodavirus, also referred to nervous necrosis virus (NNV), is the causative agent of the fatal disease, viral nervous necrosis and has brought significant economic losses in marine and freshwater cultured fish, especially larvae and juveniles. Here, we used an established invasion model with virus-like particle (VLP)-cells, mimicking orange-spotted grouper nervous necrosis virus (OGNNV), to investigate the crucial events of virus entry. VLP were observed in the perinuclear regions of Asian sea bass (SB) cells within 1...
February 8, 2017: Veterinary Research
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