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https://www.readbyqxmd.com/read/28606281/-effect-of-different-anesthetic-techniques-on-the-prognosis-of-hepatocellular-carcinoma-after-hepatectomy
#1
T Yan, J J Zhao, X Y Bi, J Q Cai, H Zheng
Objective: To investigate the influence of different anesthetic techniques on the prognosis of hepatocellular carcinoma (HCC)after hepatectomy. Methods: A total of 185 consecutive patients with HCC confirmed underwent surgery in Cancer Hospital, Chinese Academy of Medical Sciences were recruited from January 2006 to January 2008. The patients were assessed as American Society of Anesthesiologists (ASA)Ⅰ-Ⅲ, with body mass index (BMI) (22.8±4.6)kg/m(2). There were 169 males, with an average age of 56 years old and 16 females, with an average age of 53 years old...
June 13, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28540946/zinc-transporters-ybtx-and-znuabc-are-required-for-the-virulence-of-yersinia-pestis-in-bubonic-and-pneumonic-plague-in-mice
#2
Alexander G Bobrov, Olga Kirillina, Marina Y Fosso, Jacqueline D Fetherston, M Clarke Miller, Tiva T VanCleave, Joseph A Burlison, William K Arnold, Matthew B Lawrenz, Sylvie Garneau-Tsodikova, Robert D Perry
A number of bacterial pathogens require the ZnuABC Zinc (Zn(2+)) transporter and/or a second Zn(2+) transport system to overcome Zn(2+) sequestration by mammalian hosts. Previously we have shown that in addition to ZnuABC, Yersinia pestis possesses a second Zn(2+) transporter that involves components of the yersiniabactin (Ybt), siderophore-dependent iron transport system. Synthesis of the Ybt siderophore and YbtX, a member of the major facilitator superfamily, are both critical components of the second Zn(2+) transport system...
June 21, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/28489797/a-previously-published-propofol-remifentanil-response-surface-model-does-not-predict-patient-response-well-in-video-assisted-thoracic-surgery
#3
Hsin-Yi Wang, Chien-Kun Ting, Jing-Yang Liou, Kun-Hui Chen, Mei-Young Tsou, Wen-Kuei Chang
Modern anesthesia usually employs a hypnotic and an analgesic to produce synergistic sedation and analgesia. Two remifentanil-propofol interaction response surface models were used to predict sedation using Observer's Assessment of Alertness/Sedation (OAA/S) scores; one predicts an OAA/S <2 and the other <4. We hypothesized that both models would predict regained responsiveness (RR) after video-assisted thoracic surgery (VATS) to reduce total anesthesia time and make early extubation clinically relevant...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28468670/the-effect-of-dexmedetomidine-on-cerebral-perfusion-and-oxygenation-in-healthy-piglets-with-normal-and-lowered-blood-pressure-anaesthetized-with-propofol-remifentanil-total-intravenous-anaesthesia
#4
Mai Louise Grandsgaard Mikkelsen, Rikard Ambrus, Rune Rasmussen, James Edward Miles, Helle Harding Poulsen, Finn Borgbjerg Moltke, Thomas Eriksen
BACKGROUND: During anaesthesia and surgery, in particular neurosurgery, preservation of cerebral perfusion and oxygenation (CPO) is essential for normal postoperative brain function. The isolated effects on CPO of either individual anaesthetic drugs or entire anaesthetic protocols are of importance in both clinical and research settings. Total intravenous anaesthesia (TIVA) with propofol and remifentanil is widely used in human neuroanaesthesia. In addition, dexmedetomidine is receiving increasing attention as an anaesthetic adjuvant in neurosurgical, intensive care, and paediatric patients...
May 3, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28445291/efficacy-of-sevoflurane-as-an-adjuvant-to-propofol-based-total-intravenous-anesthesia-for-attenuating-secretions-in-ocular-surgery
#5
RANDOMIZED CONTROLLED TRIAL
Hou-Chuan Lai, Yun-Hsiang Chang, Ren-Chih Huang, Nan-Kai Hung, Chueng-He Lu, Jou-Hsiu Chen, Zhi-Fu Wu
BACKGROUND: The incidence of nasal secretions into the operative field is as high as 5% in ophthalmic surgery under general anesthesia. It may induce postoperative endophthalmitis. Secretions under propofol-based total intravanous anesthesia (TIVA) are greater than sevoflurane anesthesia during surgery. Postoperative nausea and vomiting (PONV) after inhalational anesthesia is higher than TIVA and may increase intraocluar pressure. We investigated the effect of sevoflurane combination with propofol-based TIVA on nasopharyngeal secretions and PONV in ocular surgery...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28374886/total-intravenous-anaesthesia-versus-inhalational-anaesthesia-for-adults-undergoing-transabdominal-robotic-assisted-laparoscopic-surgery
#6
REVIEW
Suzanne Forsyth Herling, Bjørn Dreijer, Gitte Wrist Lam, Thordis Thomsen, Ann Merete Møller
BACKGROUND: Rapid implementation of robotic transabdominal surgery has resulted in the need for re-evaluation of the most suitable form of anaesthesia. The overall objective of anaesthesia is to minimize perioperative risk and discomfort for patients both during and after surgery. Anaesthesia for patients undergoing robotic assisted surgery is different from anaesthesia for patients undergoing open or laparoscopic surgery; new anaesthetic concerns accompany robotic assisted surgery. OBJECTIVES: To assess outcomes related to the choice of total intravenous anaesthesia (TIVA) or inhalational anaesthesia for adults undergoing transabdominal robotic assisted laparoscopic gynaecological, urological or gastroenterological surgery...
April 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28328861/relationship-between-anesthesia-and-postoperative-endophthalmitis-a-retrospective-study
#7
Hou-Chuan Lai, Wei-Cheng Tseng, Shu-I Pao, Chih-Shung Wong, Ren-Chih Huang, Wei-Hung Chan, Zhi-Fu Wu
Previous study showed that patients under general anesthesia (GA) had nasopharyngeal secretions on the face at the end of ocular surgery, especially in propofol-based total intravenous anesthesia (TIVA), it might induce postoperative endophthalmitis. Therefore, we conducted a retrospective study to compare the incidence of endophthalmitis after ocular surgery under topical, inhalation anesthesia, and propofol-based TIVA in our medical center from 2011 to 2015.A total of 21,032 patients were included, and we evaluated epidemiologic factors, systemic diseases, other ocular pathologic characteristics, complications during the surgery, technique of ocular surgery, method of antibiotic prophylaxis, vitreous culture, and vision outcome in these patients...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28235523/fast-track-anesthesia-in-patients-undergoing-outpatient-laparoscopic-cholecystectomy-comparison-of-sevoflurane-with-total-intravenous-anesthesia
#8
Ceyda Özhan Çaparlar, Mehmet Özgür Özhan, Mehmet Anıl Süzer, Dilek Yazicioğlu, Mehmet Burak Eşkin, Serkan Şenkal, Mehmet Ali Çaparlar, Ersin Özkan Imren, Bülent Atik, Nedim Çekmen
BACKGROUND: The use of short-acting anesthetics has introduced a "fast-track anesthesia" concept in outpatient surgery which provides discharge of the patients from operation room directly to the phase II recovery area without entering into postanesthesia care unit. The aim of this prospective and randomized study was to compare general anesthesia using sevoflurane with propofol-remifentanil-based total intravenous anesthesia (TIVA) for fast-track eligibility in patients undergoing outpatient laparoscopic cholecystectomy...
February 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28222645/total-intravenous-anesthesia-produces-outcomes-superior-to-those-with-combined-intravenous-inhalation-anesthesia-for-laparoscopic-gynecological-surgery-at-high-altitude
#9
Rui Xu, Shuqin Zhou, Jin Yang, Haiyan Li, Qingguo Zhang, Guohong Zhang, Shiyuan Xu, Qing Peng
Objective We compared efficacy and adverse outcomes following totally intravenous anesthesia (TIVA) versus combined intravenous-inhalation anesthesia (CIVIA) on hemodynamics and postoperative recovery following laparoscopic gynecological (LG) surgery at high altitudes. Methods We enrolled 80 ASA I or II patients scheduled for LG surgery and randomly assigned them to TIVA with propofol (group P, n = 40) or CIVIA with isoflurane (group I, n = 40). Mean arterial pressure, heart rate, pulse oxygen saturation, and partial pressure of end-tidal carbon dioxide were measured at various time points...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28213945/optimization-of-initial-propofol-bolus-dose-for-eeg-narcotrend-index-guided-transition-from-sevoflurane-induction-to-intravenous-anesthesia-in-children
#10
Nils Dennhardt, Dietmar Boethig, Christiane Beck, Sebastian Heiderich, Martin Boehne, Andreas Leffler, Barbara Schultz, Robert Sümpelmann
BACKGROUND: Sevoflurane induction followed by intravenous anesthesia is a widely used technique to combine the benefits of an easier and less traumatic venipuncture after sevoflurane inhalation with a recovery with less agitation, nausea, and vomiting after total intravenous anesthesia (TIVA). Combination of two different anesthetics may lead to unwanted burst suppression in the electroencephalogram (EEG) during the transition phase. OBJECTIVE: The objective of this prospective clinical observational study was to identify the optimal initial propofol bolus dose for a smooth transition from sevoflurane induction to TIVA using the EEG Narcotrend Index (NI)...
April 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28207547/planning-for-operating-room-efficiency-and-faster-anesthesia-wake-up-time-in-open-major-upper-abdominal-surgery
#11
Hou-Chuan Lai, Shun-Ming Chan, Chueng-He Lu, Chih-Shung Wong, Chen-Hwan Cherng, Zhi-Fu Wu
Reducing anesthesia-controlled time (ACT) may improve operation room (OR) efficiency result from different anesthetic techniques. However, the information about the difference in ACT between desflurane (DES) anesthesia and propofol-based total intravenous anesthesia (TIVA) techniques for open major upper abdominal surgery under general anesthesia (GA) is not available in the literature.This retrospective study uses our hospital database to analyze the ACT of open major upper abdominal surgery without liver resection after either desflurane/fentanyl-based anesthesia or TIVA via target-controlled infusion with fentanyl/propofol from January 2010 to December 2011...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28190788/a-comparison-of-cardiopulmonary-effects-and-anaesthetic-requirements-of-two-dexmedetomidine-continuous-rate-infusions-in-alfaxalone-anaesthetized-greyhounds
#12
Setefilla Quirós-Carmona, Rocío Navarrete, Juan M Domínguez, María Del Mar Granados, Rafael J Gómez-Villamandos, Pilar Muñoz-Rascón, Daniel Aguilar, Francisco J Funes, Juan Morgaz
OBJECTIVE: To determine the effects of two dexmedetomidine continuous rate infusions on the minimum infusion rate of alfaxalone for total intravenous anaesthesia (TIVA), and subsequent haemodynamic and recovery effects in Greyhounds undergoing laparoscopic ovariohysterectomy. STUDY DESIGN: Prospective, randomized and blinded clinical study. ANIMALS: Twenty-four female Greyhounds. METHODS: Dogs were premedicated with dexmedetomidine 3 μg kg(-1) and methadone 0...
March 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28183546/sevoflurane-preserves-regional-cerebral-oxygen-saturation-better-than-propofol-randomized-controlled-trial
#13
Tomislav Ružman, Tatjana Šimurina, Danijela Gulam, Nataša Ružman, Maja Miškulin
STUDY OBJECTIVE: To investigate possible effects of volatile induction and maintenance anesthesia with sevoflurane (VIMA) and total intravenous anesthesia with propofol (TIVA) on regional cerebral oxygen saturation (rcSo2) during laparoscopic cholecystectomy. DESIGN: Randomized, prospective and single-blinded study. SETTING: Academic hospital. PATIENTS: ASA physical status of I and II surgical patients, scheduled for elective laparoscopic cholecystectomy from March 2013 to October 2014...
February 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28096580/randomized-double-blind-comparison-of-remifentanil-and-alfentanil-in-patients-undergoing-laparoscopic-cholecystectomy-using-total-intravenous-anesthesia
#14
José M Beleña, Mónica Núñez, Alfonso Vidal, Diego Anta
BACKGROUND AND AIMS: To compare the use of remifentanil and alfentanil to suppress intraoperative adrenergic response of pain and the influence of these drugs on the recovery profile in patients undergoing laparoscopic cholecystectomy using a total intravenous anesthesia (TIVA) technique. MATERIAL AND METHODS: One hundred patients undergoing elective laparoscopic cholecystectomy were randomized to be managed with either remifentanil (group R) or alfentanil (group A)...
October 2016: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/28027562/microcirculation-violations-of-the-conjunctiva-in-clean-up-workers-of-the-chornobyl-npp-accident
#15
P A Fedirko, N A Garkava
OBJECTIVE: Explore hemomicrocirculation changes after radiation exposure depending of irradiation dose in dynam ics. MATERIALS AND METHODS: The research conducted on 470 clean up workers of the Chornobyl NPP accident. After 10-15 years after radiation exposure examined 450 Chornobyl clean up workers in age of 28 to 65 years. The con trol group consisted of 110 industrial workers who had not a contact of IR. In 22 years after radiation exposure sep arately examined 20 randomly selected Chornobyl clean up workers accident...
December 2016: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/27930529/effects-of-propofol-and-sevoflurane-on-perioperative-immune-response-in-patients-undergoing-laparoscopic-radical-hysterectomy-for-cervical-cancer
#16
RANDOMIZED CONTROLLED TRIAL
Songtao Liu, Xinyu Gu, Lijiao Zhu, Guannan Wu, Hai Zhou, Yan Song, Congyou Wu
The aim of this study is to compare the effects of propofol and sevoflurane anesthesia on perioperative immune response in patients undergoing laparoscopic radical hysterectomy for cervical cancer.Sixty patients with cervical cancer scheduled for elective laparoscopic radical hysterectomy under general anesthesia were randomized into 2 groups. TIVA group received propofol induction and maintenance and SEVO group received sevoflurane induction and maintenance. Blood samples were collected at 30 min before induction (T0); the end of the operation (T1); and 24 h (T2), 48 h (T3), and 72 h (T4) after operation...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27904618/assessment-of-different-anesthesia-depth-under-total-intravenous-anesthesia-on-postoperative-cognitive-function-in-laparoscopic-patients
#17
Delin Zhang, Aiqing Nie
BACKGROUND: This study aimed to compare the effects of different depths of sedation during total intravenous anesthesia (TIVA) with remifentanil and propofol given by target-controlled infusion (TCI) on postoperative cognitive function in young and middle-aged patients undergoing gynecological laparoscopic surgery. MATERIALS AND METHODS: A total of 150 American Society of Anesthesiologists physical Status I/II patients scheduled for gynecological laparoscopic operation were randomly divided into three groups...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27797096/a-comparison-of-bis-recordings-during-propofol-based-total-intravenous-anaesthesia-and-sevoflurane-based-inhalational-anaesthesia-in-obese-patients
#18
COMPARATIVE STUDY
Tomasz Gaszyński, Andrzej Wieczorek
BACKGROUND: Intraoperative awareness is a rarely occurring phenomenon. Obesity is considered as one of the factors increasing the probability of intraoperative awareness due to problems with the dosing of anaesthetics. In a randomized prospective study we compared bispectral index (BIS) recordings during propofol-based total intravenous anaesthesia (TIVA) and sevoflurane-based inhalation anaesthesia in morbidly obese patients as a sign of possible intraoperative awareness. METHODS: 120 morbidly obese patients were randomly allocated into two subgroups: TIVA or SEVO...
2016: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/27771984/the-effects-of-adding-ischemic-preconditioning-during-desflurane-inhalation-anesthesia-or-propofol-total-intravenous-anesthesia-on-pneumoperitoneum-induced-oxidative-stress
#19
RANDOMIZED CONTROLLED TRIAL
Safinaz Karabayirli, Onder Surgit, Hulya Kasikara, Cemile Koca Bicer, Merve Ergin, Ruveyda Irem Demircioglu, Bunyamin Muslu
BACKGROUND: The aim of the study was to explore the differences in oxidative stress during anesthesia with desflurane/N2O or propofol/remifentanil in patients undergoing laparoscopic cholecystectomy and additionally to evaluate the differential effects of desflurane and propofol on ischemic preconditioning (IP). MATERIALS AND METHODS: One hundred patients were randomly allocated to four groups. For anesthesia maintenance, the inhalation group (Group I) and the inhalation plus IP group (Group IIP) received desflurane at an end-tidal concentration of 4-6 vol% in oxygen/N2O, and the TIVA group (Group T) and TIVA plus IP group (Group TIP) received infusions of propofol and remifentanil...
February 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27736225/use-of-propofol-for-induction-and-maintenance-of-anesthesia-in-a-king-penguin-aptenodytes-patagonicus-undergoing-magnetic-resonance-imaging
#20
Sarah E Bigby, Jennifer E Carter, Sébastien Bauquier, Thierry Beths
Anesthesia protocols for patients with intracranial lesions need to provide hemodynamic stability, preserve cerebrovascular autoregulation, avoid increases in intracranial pressure, and facilitate a rapid recovery. Propofol total intravenous anesthesia (TIVA) maintains cerebral blood flow autoregulation and is considered superior to inhalant agents as an anesthetic protocol for patients with intracranial lesions. A propofol-based TIVA subsequent to premedication with medetomidine and diazepam was used in a king penguin ( Aptenodytes patagonicus ) undergoing magnetic resonance imaging of the brain after a new onset of seizures...
September 2016: Journal of Avian Medicine and Surgery
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