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https://www.readbyqxmd.com/read/28662995/simplifying-the-human-serum-proteome-for-discriminating-patients-with-bipolar-disorder-of-other-psychiatry-conditions
#1
Jemmyson Romário de Jesus, Rodrigo Moretto Galazzi, Tatiani Brenelli de Lima, Cláudio Eduardo Muller Banzato, Luiz Fernando de Almeida Lima E Silva, Clarissa de Rosalmeida Dantas, Fábio Cézar Gozzo, Marco Aurélio Zezzi Arruda
PURPOSE: An exploratory analysis using proteomic strategies in blood serum of patients with bipolar disorder (BD), and with other psychiatric conditions such as Schizophrenia (SCZ), can provide a better understanding of this disorder, as well as their discrimination based on their proteomic profile. METHODS: The proteomic profile of blood serum samples obtained from patients with BD using lithium or other drugs (N=14), healthy controls, including non-family (HCNF; N=3) and family (HCF; N=9), patients with schizophrenia (SCZ; N=23), and patients using lithium for other psychiatric conditions (OD; N=4) were compared...
June 26, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28657366/psychiatric-disorders-acne-and-systemic-retinoids-comparison-of-risks
#2
M Le Moigne, S Bulteau, Marie Grall-Bronnec, M Gerardin, Jean-Pascal Fournier, A P Jonville-Bera, Pascale Jolliet, Brigitte Dreno, C Victorri-Vigneau
BACKGROUND: The link between isotretinoin, treatment of a severe form of acne, and psychiatric disorders remains controversial, as acne itself could explain the occurrence of psychiatric disorders. This study aims at assessing the disproportionality of psychiatric adverse events reported with isotretinoin in the French National PharmacoVigilance Database, compared with other systemic acne treatments and systemic retinoids. MATERIALS AND METHODS: Data were extracted from the French National PharmacoVigilance Database for systemic acne treatments, systemic retinoids and drugs used as comparators...
June 28, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28631890/oxidative-stress-and-psychiatric-morbidity-in-patients-with-facial-acne
#3
Sara M Awad, Hanan Morsy, Ayat A Sayed, Nahed A Mohamed, Ghada M Ezzat, Mostafa M Noaman
BACKGROUND: Acne vulgaris is a common cosmetic problem that is frequently associated with psychosocial disturbances as well as increased oxidative stress. However, oxidative stress and psychological aspects have been studied separately in acne. OBJECTIVE: To evaluate the relationships between oxidative stress, anxiety, depression, and quality of life in acne patients. METHODS: Sixty patients with facial acne and 40 age- and sex-matched healthy individuals were included in the study...
June 20, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28545486/depression-in-patients-with-sapho-syndrome-and-its-relationship-with-brain-activity-and-connectivity
#4
Jie Lu, Yanping Duan, Zhentao Zuo, Wenrui Xu, Xuewei Zhang, Chen Li, Rong Xue, Hanzhang Lu, Weihong Zhang
BACKGROUND: Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a rare disease and there is no related literature concerning psychiatric symptoms in SAPHO patients. Thus, we believe that this will be the first paper to explore the episode and the neurobiological basis of depression symptoms in SAPHO patients using resting state functional magnetic resonance imaging (rs-fMRI). Twenty-eight SAPHO patients and fifteen age- and gender- matched normal controls (NC) were consecutively submitted to psychiatric evaluation and rs-fMRI scanning...
May 25, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28511829/suicidal-behaviors-in-the-dermatology-patient
#5
Madhulika A Gupta, Daiana R Pur, Branka Vujcic, Aditya K Gupta
An assessment of suicidal behaviors in the dermatology patient may be necessary in several situations: (1) in the presence of psychiatric comorbidity (major depressive disorder, body dysmorphic disorder, substance use disorder, posttraumatic stress disorder), encountered in up to 30% of dermatology patients; (2) when dermatologic symptoms ("dysmorphophobia," dermatitis artefacta) represent psychiatric pathologic conditions; (3) when psychosocial stressors (bereavement, interpersonal violence) increase the risk of suicidal behavior and exacerbate stress-reactive dermatoses (psoriasis, acne); (4) in the presence of high disease burden (chronicity, increased disease severity); (5) in instances of significant pruritus or chronic sleep disruption; (6) in the presence of facial lesions or facial scarring; (7) when social exclusion or feelings of alienation arise secondary to the skin disorder; (8) with use of medications (retinoids, biologics) for which suicidal behavior has been implicated as a possible side effect; and (9) when treating psychiatric patients experiencing a serious reaction to psychotropic medications (eg, Stevens-Johnson syndrome and anticonvulsants)...
May 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28295859/adverse-effects-of-isotretinoin-a-large-retrospective-review
#6
Piotr Brzezinski, Katarzyna Borowska, Anca Chiriac, Janusz Smigielski
Acne is a very common and disfiguring disease that affects mostly adolescents and, to some extent, adults. The objective of our study was to estimate the adverse effects after isotretinoin by treatment of 3,525 patients due to acne vulgaris in a 5-year observation. Retrospective, comparative study was carried out in Poland and Romania from January 2012 to August 2016. Inclusion criteria into this study were moderate, severe, and nodulocystic inflammatory acne vulgaris. Exclusion criteria were mild acne, pregnant, and lactating women...
March 14, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28196993/personality-disorders-and-its-association-with-anxiety-and-depression-among-patients-of-severe-acne-a-cross-sectional-study-from-eastern-india
#7
Sharmila Sarkar, Paramita Patra, Kakali Mridha, Sudip Kumar Ghosh, Asish Mukhopadhyay, Rajarshi Guha Thakurta
BACKGROUND: In many patients, emotional stress may exacerbate acne. Psychological problems such as social phobias, low self-esteem, or depression may also occur as a result of acne. The presence of acne may have some negative effect on the quality of life, self-esteem, and mood of the affected patients. While some studies have been undertaken about anxiety, depression, and personality patterns in patients with acne, only a few studies have been done to identify specific personality disorders in patients with acne...
October 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/27981606/evaluation-of-cutaneous-findings-in-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-a-preliminary-study
#8
Hilal Kaya Erdogan, Saniye Tulin Fıdan, Isil Bulur, Tekden Karapınar, Zeynep Nurhan Saracoglu
Attention deficit hyperactivity disorder (ADHD) is characterized by attention, concentration, mobility, and impulse control problems and is among the most frequently seen psychiatric disorders during childhood. Our aim was to evaluate cutaneous findings in children and adolescents with ADHD. In our study we found that onychophagy, traumatic skin changes, atopy and related symptoms, certain birthmarks, and acne were frequent cutaneous findings in children with ADHD. Although a limitation is the lack of a control group, ADHD is very common, and our study suggests that further studies of cutaneous findings and ADHD are warranted...
March 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/27817838/noncontraceptive-use-of-oral-combined-hormonal-contraceptives-in-polycystic-ovary-syndrome-risks-versus-benefits
#9
REVIEW
Anuja Dokras
The use of steroid sex hormones for noncontraceptive benefits has been endorsed by several medical societies. In women with polycystic ovary syndrome (PCOS), hormonal contraceptives are first-line therapy for concurrent treatment of menstrual irregularity, acne, and hirsutism. The association of PCOS with obesity, diabetes, and dyslipidemia frequently brings up the debate regarding risks versus benefits of hormonal contraceptives in this population. In women with PCOS, the lack of large-scale studies evaluating the risks with varying doses of ethinyl estradiol, types of progestins, and presence of confounding factors such as obesity, smoking, and other cardiometabolic comorbidities is a significant limitation in these deliberations...
December 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27784999/interventions-to-increase-adherence-to-acne-treatment
#10
REVIEW
Sara Moradi Tuchayi, Tiffany M Alexander, Anish Nadkarni, Steven R Feldman
BACKGROUND: Adherence to acne medication is poor and is a major reason why treatment plans are ineffective. Recognizing solutions to nonadherence is critical. OBJECTIVE: The purpose of this study is to describe the hurdles associated with acne nonadherence and to provide mechanisms on how to ameliorate them. METHODS: PubMed database was searched. Of the 419 search results, 29 articles were reviewed to identify hurdles to adherence and corresponding solutions...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27508953/evaluation-of-social-anxiety-self-esteem-life-quality-in-adolescents-with-acne-vulgaris
#11
Dilek Unal, Nazan Emiroğlu, Fatma Pelin Cengiz
BACKGROUND: Acne vulgaris is a visible skin disease commonly seen in adolescence. As it affects the appearance, it is likely to bring stress to the adolescent's life regarding sensitivity about their appearance. OBJECTIVE: The aim of the study was to investigate the social anxiety level, acne-specific life quality, and self-esteem among adolescents with acne vulgaris. In addition, we evaluated the relationship between these parameters, clinical severity, and sociodemographic data...
August 5, 2016: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/27498379/body-dysmorphic-disorder-in-different-settings-a-systematic-review-and-estimated-weighted-prevalence
#12
REVIEW
David Veale, Lucinda J Gledhill, Polyxeni Christodoulou, John Hodsoll
Our aim was to systematically review the prevalence of body dysmorphic disorder (BDD) in a variety of settings. Weighted prevalence estimate and 95% confidence intervals in each study were calculated. The weighted prevalence of BDD in adults in the community was estimated to be 1.9%; in adolescents 2.2%; in student populations 3.3%; in adult psychiatric inpatients 7.4%; in adolescent psychiatric inpatients 7.4%; in adult psychiatric outpatients 5.8%; in general cosmetic surgery 13.2%; in rhinoplasty surgery 20...
September 2016: Body Image
https://www.readbyqxmd.com/read/27498285/-acne-in-cameroon-quality-of-life-and-psychiatric-comorbidities
#13
MULTICENTER STUDY
E A Kouotou, H Adegbidi, R Bene Belembe, I Sieleunou, J R Nansseu, J-P Kamga, E C Ndjitoyap Ndam
BACKGROUND AND AIMS: The impact of acne upon quality of life (QOL) among affected patients had not previously been investigated in Cameroon. The present study therefore sought to assess the QOL of patients with acne and related psychiatric comorbidities in this country. PATIENTS AND METHODS: This was a cross-sectional study conducted in three hospitals in Yaoundé, Cameroon. We included patients diagnosed with acne after a consultation with a dermatologist, and who consented to participate in the study...
October 2016: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27424511/-emotions-and-bodily-experience-in-hidradenitis-suppurative-acne-inversa
#14
S Tugnoli, V Bettoli, C Agnoli, S Caracciolo
Hidradenitis Suppurative-Acne Inversa is one of the most debilitating chronic skin diseases. It seriously affects the emotional and relational life of the patient, it has a significant psychiatric comorbidity and it impairs the quality of life. We present the report of a clinical situation with onset of the illness in a young woman during pregnancy, a case characterized by particular evolution, severe systemic involvement, strong psycho-emotional impact on the patient and impairment of subjective well-being of the caregiver...
May 2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/27344625/affective-disorders-as-potential-complication-of-anti-acne-treatment-with-isotretinoin-a-case-series
#15
Karakula-Juchnowicz Hanna, Kowal-Popczak Agnieszka, Dzikowski Michal, Juchnowicz Dariusz, Dzikowska Izabela, Makarewicz Agata, Dubas-Slemp Halina
OBJECTIVE: To analyse cases of 9 patients (18-27 yo) who were consequently admitted to our department and treated with affective disorders (AD) while undergoing isotretinoin (INN) therapy. METHODS: A semi-structured questionnaire designed by the authors was used to analyse many variables related to demographic characteristics, dermatologic and psychiatrics symptoms, AD course and treatment, family history of mental disorders, building on medical histories of patients and their families, and available medical records...
November 1, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27014604/isotretinoin-was-not-associated-with-depression-or-anxiety-a-twelve-week-study
#16
Bella Suarez, Ana Serrano, Yves Cova, Trino Baptista
AIM: To investigate the frequency and severity of depression and/or anxiety in isotretinoin (ITT)-treated subjects and in a non-ITT control group. METHODS: Sixty consecutively-admitted non-psychiatric outpatients with acne were assigned to either ITT at a fixed dose of 30 mg/d (n = 36) or "other treatment" group (OT; n = 24). The Zung depression or anxiety scales (with cut-off points), two locally developed scales for depression (GeDepr) and anxiety (Ansilet) (without cut-off points) and clinical global impression scales of acne severity were administered at baseline and at weeks 6 and 12 of treatment...
March 22, 2016: World Journal of Psychiatry
https://www.readbyqxmd.com/read/26955128/a-case-report-of-isotretinoin-induced-manic-psychosis
#17
Jisha M Lucca, Niphy Annie Varghese, Madhan Ramesh, Dushad Ram
Isotretinoin, an oral vitamin A derivative, used to treat severe treatment-resistant acne. Psychiatric side effects of isotretinoin particularly depression and suicidal thoughts have been well documented. We report a case of isotretinoin-induced manic psychosis in a young female without a family history and history of mental illness.
January 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/26818062/social-anxiety-and-quality-of-life-in-vitiligo-and-acne-patients-with-facial-involvement-a-cross-sectional-controlled-study
#18
COMPARATIVE STUDY
Andac Salman, Emel Kurt, Volkan Topcuoglu, Zeynep Demircay
BACKGROUND: Vitiligo and acne vulgaris, commonly affecting the face, have significant psychological effects and impair the quality of life of the affected individuals. Because of their negative effect on physical appearance, these conditions may act as a potential barrier to social relationships and cause social anxiety. OBJECTIVE: The objective of the study was to investigate the social anxiety, quality of life, anxiety, and depression levels of acne and vitiligo patients with facial involvement and compare these levels with healthy controls...
June 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/26703328/-is-it-her-hormones-psychiatric-diagnoses-and-polycystic-ovarian-syndrome
#19
Ann Genovese, Teri Smith, Holly Kramer, Marilyn Augustyn
Beth, whom you have cared for in your primary care practice since she was born, is a 15-year-old adolescent girl with no prior psychiatric history who developed significant symptoms of clinical depression, associated with self-injurious behavior (cutting on wrists, arms, and thighs). She denied any known precipitant for her depression.She is a ninth grade honors student in the gifted program at a local high school and is described as a talented musician, playing multiple musical instruments as well as soccer and basketball...
January 2016: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/26677293/psychological-morbidity-among-dermatological-patients-in-a-rural-setting
#20
Sandeep Krishna Murthy Kosaraju, Karumuri Siva Rami Reddy, Naresh Vadlamani, Lakkireddy Sandhya, Lokesh Kalasapati, Sowmya Maganti, Amudha Mary
BACKGROUND: Dermatological conditions have an impact on psychology of the patients. There is a dearth of studies regarding this field in Rural population of India. AIMS AND OBJECTIVES: The primary objective of this study is to evaluate the psychiatric morbidity in patients affected with Dermatological condition in a rural population and secondary objective is to assess the morbidity in dimensions of Depression Severity and the quality of life in the Emotional Sphere, Physical Symptoms, Psychosocial Functioning...
November 2015: Indian Journal of Dermatology
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