Alayne P Meyer, Jianing Ma, Guy Brock, Sayaka Hashimoto, Catherine E Cottrell, Mariam Mathew, Jesse M Hunter, Marco L Leung, Don Corsmeier, Vijayakumar Jayaraman, Megan A Waldrop, Kevin M Flanigan
INTRODUCTION/AIMS: Exome sequencing (ES) has proven to be a valuable diagnostic tool for neuromuscular disorders, which often pose a diagnostic challenge. The aims of this study were to investigate the clinical outcomes associated with utilization of ES in the pediatric neuromuscular clinic and to determine if specific phenotypic features or abnormal neurodiagnostic tests were predictive of a diagnostic result. METHODS: This was a retrospective medical record review of 76 pediatric neuromuscular clinic patients who underwent ES...
October 3, 2023: Muscle & Nerve