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https://www.readbyqxmd.com/read/29217521/laser-balloon-or-wide-area-circumferential-irrigated-radiofrequency-ablation-for-persistent-atrial-fibrillation-a-multicenter-prospective-randomized-study
#1
Boris Schmidt, Petr Neuzil, Armin Luik, Joaquin Osca Asensi, Jan Wilko Schrickel, Thomas Deneke, Stefano Bordignon, Jan Petru, Matthias Merkel, Lucie Sediva, Annemarie Klostermann, Laura Perrotta, Oscar Cano, K R Julian Chun
BACKGROUND: Pulmonary vein isolation is the cornerstone of ablation for persistent atrial fibrillation (AF). The role of balloon catheters in this patient population remains ill defined. We sought to compare efficacy and safety of the laser balloon (LB) with wide-area circumferential pulmonary vein isolation using irrigated radiofrequency current (RF) ablation and 3-dimensional mapping. METHODS AND RESULTS: In 6 European centers, patients with persistent AF were prospectively randomized...
December 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29216412/insights-into-ablation-of-persistent-atrial-fibrillation-lessons-from-6-year-clinical-outcomes
#2
Andreas Metzner, Stephanie Brooks, Peter Wohlmuth, Tina Lin, Erik Wissner, Roland Tilz, Andreas Rillig, Shibu Mathew, Ardan Saguner, Christian Heeger, Christian Sohns, Karl-Heinz Kuck, Feifan Ouyang
INTRODUCTION: Ablation of persistent atrial fibrillation (AF) is a potential treatment option for symptomatic patients. We sought to evaluate the critical role of circumferential pulmonary vein isolation (CPVI) in the ablation of persistent AF. METHODS AND RESULTS: A total of 341 ablation procedures were performed in 174 consecutive patients with persistent AF. CPVI was performed in all patients, additional ablation was only performed if electrical cardioversion failed after CPVI...
December 7, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29211857/pulmonary-vein-isolation-with-vs-without-continued-antiarrhythmic-drug-treatment-in-subjects-with-recurrent-atrial-fibrillation-powder-af-results-from-a-multicentre-randomized-trial
#3
Mattias Duytschaever, Anthony Demolder, Thomas Phlips, Andrea Sarkozy, Milad El Haddad, Philippe Taghji, Sebastien Knecht, Rene Tavernier, Yves Vandekerckhove, Tom De Potter
Aims: Catheter ablation is indicated in patients with symptomatic paroxysmal atrial fibrillation (AF) resistant to antiarrhythmic drug therapy (ADT). We investigated whether continued use of previously ineffective ADT beyond the post-ablation blanking period reduces recurrence of atrial tachyarrhythmia within the 1st year after ablation. Methods and results: This was a multicentre, randomized controlled study in patients undergoing contact force-guided pulmonary vein isolation (PVI) for paroxysmal AF in whom previously ineffective ADT was continued during a blanking period of 3 months...
December 2, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29211301/outcome-in-patients-with-left-common-pulmonary-vein-after-cryoablation-with-second-generation-cryoballoon
#4
Thomas Beiert, Pia C Lodde, Lutz P T Linneborn, Jessica Werner, Lisa Prinz, Florian Stöckigt, Markus Linhart, Lars Lickfett, Georg Nickenig, Jan W Schrickel, René P Andrié
BACKGROUND: Pulmonary vein isolation (PVI) has become a widely accepted therapy in patients suffering from symptomatic atrial fibrillation (AF). HYPOTHESIS: AF-free survival differs in patients with left common pulmonary vein (LCPV) after PVI with second generation cryoballoon. METHODS: We included patients scheduled for first PVI for paroxysmal or persistent AF. Symptomatic and/or documented arrhythmia episodes (> 30 s) were defined as AF recurrence, excluding a three month blanking period...
December 6, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29209114/combined-endovascular-brachytherapy-sorafenib-and-transarterial-chemobolization-therapy-for-hepatocellular-carcinoma-patients-with-portal-vein-tumor-thrombus
#5
Zi-Han Zhang, Qing-Xin Liu, Wen Zhang, Jing-Qin Ma, Jian-Hua Wang, Jian-Jun Luo, Ling-Xiao Liu, Zhi-Ping Yan
AIM: To evaluate the safety and efficacy of combined endovascular brachytherapy (EVBT), transarterial chemoembolization (TACE), and sorafenib to treat hepatocellular carcinoma (HCC) patients with main portal vein tumor thrombus (MPVTT). METHODS: This single-center retrospective study involved 68 patients with unresectable HCC or those who were unfit for liver transplantation and percutaneous frequency ablation according to the BCLC classification. All patients had Child-Pugh classification grade A or B, Eastern Cooperative Oncology Group (ECOG) performance status of 0-2, and MPVTT...
November 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29208256/combined-cryoballoon-and-radiofrequency-ablation-versus-radiofrequency-ablation-alone-for-long-standing-persistent-atrial-fibrillation
#6
Tümer Erdem Guler, Tolga Aksu, Kivanc Yalin, Sukriye Ebru Golcuk, Ferit Onur Mutluer, Serdar Bozyel
BACKGROUND: To achieve sinus rhythm, ablation of long-standing persistent atrial fibrillation (LSPAF) usually requires substrate modification in addition to pulmonary vein isolation (PVI). In the present article, we aimed to compare clinical and substrate modification effects of 2 distinct PVI strategies during stepwise ablation in patients with LSPAF: (1) Combined approach: cryoballoon (CB) for PVI and radiofrequency (RF) ablation for substrate modification and (2) RF-only approach: RF ablation for both PVI and substrate modification...
December 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29207690/morphological-and-morphometric-study-of-coronary-sinus-in-north-indian-population
#7
Beegum Zabina, Rajan Kumar Singla, Ravi Kant Sharma, Neelam Bala
Introduction: Coronary sinus (CS) is the largest vein draining the blood from heart. It is a muscular tube of about 2 cm to 3 cm length and 1 cm in caliber. It has become a clinically important structure through its role in providing access for different cardiac procedures viz., biventricular pacing, arrhythmia ablation and for deployment of an array of cardiac devices. Aim: To study the location, shape, length and width of CS including its left atrial muscular coverage in 50 cadaveric hearts...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29202532/-premature-outflow-tract-ventricular-contraction-combined-with-complete-bundle-branch-block-the-characteristic-electrocardiographic-and-ablation-target-potential-features
#8
C Y Di, Z Wan, K Li, Y S Ding, W H Lin
Objective: To explore the characteristics of electrocardiogram(ECG) and target potential features of premature ventricular contraction (PVC) in patients with complete left/right bundle branch block (CL/RBBB) and compare with those without CL/RBBB. Methods: A retrospective analysis was done in 8 outflow tract PVC patients with CL/RBBB, who successfully underwent radiofrequency ablation from August 2009 to June 2017. According to the bundle branch block chamber, patients were divided into the complete right bundle branch block (CRBBB) group (n=4) and the complete left bundle branch block (CLBBB) group (n=4)...
December 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29200088/totally-thoracoscopic-pulmonary-vein-isolation-a-simplified-technique
#9
Meelad I H Al-Jazairi, Theo J Klinkenberg, Bart P Van Putte, Massimo A Mariani, Stefano Benussi
Since the introduction of thoracoscopic ablation for atrial fibrillation (AF), the field of minimally invasive AF treatment has evolved toward an established treatment option for AF, with an overall 2-year antiarrhythmic drug free success rate of 77%. Complications are usually minor, and the incidence of bleeding needing conversion to sternotomy or (mini-)thoracotomy varies between 0% and 1.6%. Bleeding is often related to encircling the pulmonary veins, which is a blind maneuver that has to be done without direct camera vision...
December 1, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29197190/percutaneous-treatment-with-radiofrequency-ablation-of-varicose-veins-recurring-after-vein-stripping-surgery-a-preliminary-study
#10
Giovanni Turtulici, Ermenegildo Furino, Giorgia Dedone, Riccardo Sartoris, Jeries Zawaideh, Aldo Fischetti, Enzo Silvestri, Gennaro Quarto
AIM: The aim of our study was to evaluate the efficacy of a new treatment of recurrent varicose vein after stripping of the great saphenous vein with rigid radiofrequency needles. MATERIAL OF STUDY: 37 patients enrolled (11 males and 26 females). 10 patients had recurrent varicose veins for the presence of residual reflux in the Saphenous-Femoral Junction (SFJ) stump, whilst 21 patients for the presence of a single or multiple re-chanalized and refluxing perforator veins, and 6 had mixed rechanalization due to perforator veins and refluxing saphenous stump...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29196089/atrial-fibrillation-ablation-with-the-second-generation-cryoballoon-multicenter-propensity-score-matched-comparison-between-freezing-strategies
#11
Erwin Ströker, Kaspars Kupics, Carlo de Asmundis, Giacomo Mugnai, Valentina de Regibus, Jeroen De Cocker, Dirk Stockman, Saverio Iacopino, Juan Sieira-Moret, Pedro Brugada, Bruno Schwagten, Yves De Greef, Gian-Battista Chierchia
BACKGROUND: Second generation cryoballoon (CB-A) ablation is highly effective in achieving pulmonary vein (PV) isolation and freedom from atrial fibrillation (AF). However, the ideal freezing strategy is still under debate. Our objective was to investigate the efficacy and outcome between different freezing strategies used with the CB-A in a multicenter, matched population. METHODS: From a total cohort of 1018 patients having undergone CB-A ablation for drug-refractory AF, 673 patients with follow-up ≥6months were included and stratified according to the applied freezing strategy: bonus freeze (BF) versus single freeze (SF)...
November 22, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29194518/coincidental-ganglionated-plexus-modification-during-radiofrequency-pulmonary-vein-isolation-and-post-ablation-arrhythmia-recurrence
#12
Georgios Giannopoulos, Charalampos Kossyvakis, Christos Angelidis, Vasiliki Panagopoulou, Dimitrios Tsiachris, Dimitrios A Vrachatis, Konstantinos Doudoumis, Konstantinos Letsas, Stamatina Pagoni, Christodoulos Stefanadis, Vassilios P Vassilikos, John Lekakis, Spyridon Deftereos
Aims: Vagal responses (VR) during left atrial ablation for atrial fibrillation (AF) treatment have been reported to be associated with less recurrences, presumably because they are a sign of ganglionated plexi modification. Our objective was to evaluate whether coincidentally elicited VR during left atrial ablation are associated with lower AF recurrence rates. Methods and results: This is a post hoc analysis of a prospective study of 291 patients with paroxysmal AF undergoing radiofrequency pulmonary vein isolation (PVI)...
December 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29191055/recurrence-after-pulmonary-vein-isolation-is-associated-with-low-contact-force
#13
Bawer Jalal Tofig, Peter Lukac, Rune Borregaard, Jan Møller Nielsen, Henrik Kjærulf Jensen, Christian Gerdes, Jens Kristensen, Jens Cosedis Nielsen, Steen Buus Kristiansen
OBJECTIVES: Recurrent arrhythmia after pulmonary vein isolation (PVI) by radiofrequency (RF) ablation in patients with atrial fibrillation (AFIB) remains a significant challenge. Using contact force (CF) sensing ablation catheters, we aimed to identify procedure related parameters associated with recurrence after de-novo PVI in patients with AFIB. METHODS: Consecutive patients undergoing a de-novo PVI procedure (n = 120, 63% paroxysmal and 37% persistent AFIB) employing a force-sensing ablation catheter were included...
November 30, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/29187667/strategy-and-outcome-of-catheter-ablation-for-persistent-atrial-fibrillation%C3%A3-impact-of-progress-in-the-mapping-and-ablation-technologies
#14
Hideharu Okamatsu, Ken Okumura
Pulmonary vein (PV) antrum isolation (PVAI) is effective in treating paroxysmal atrial fibrillation (AF) but is less so for persistent AF. A recent randomized study on the ablation strategies for persistent AF demonstrated that 2 common atrial substrate modifications, creation of linear lesions in the left atrium and ablation of complex fractionated electrogram sites, in addition to PVAI did not improve the outcome compared with stand-alone PVAI, suggesting the necessity of a more individualized, selective approach to persistent AF...
November 30, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29186938/occurrence-and-clinical-characteristics-of-hepatocellular-carcinoma-in-the-north-eastern-poland
#15
Paweł Kozłowski, Anna Parfieniuk-Kowerda, Aleksander Tarasik, Marcin Januszkiewicz, Agnieszka Czauż-Andrzejuk, Tadeusz wojciech Łapiński, Robert Flisiak
Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the third leading cause of cancerrelated mortality worldwide. Risk factors for this malignancy include liver cirrhosis, HBV or HCV infection, fatty liver disease. THE AIM OF STUDY: This study aims to assess the occurrence and clinical characteristics of HCC in the Northeastern Poland between 2011 and 2015. The number of primary lesions, their size and location within the liver were analysed. The risk factors for this cancer in studied population have been identified...
2017: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/29183028/radiofrequency-ablation-of-atrial-fibrillation-in-patients-with-ebstein-s-anomaly-a-two-case-report
#16
Konstantinos E Iliodromitis, Marc Bonsels, Rolf Borchard, Anja Dorszewski
Ebstein's anomaly (EA) is a rare congenital heart disease characterized by "atrialization" of the right ventricle, due to apical displacement of the tricuspid leaflets into the right ventricle. Patients with EA may develop all kinds of supraventricular arrhythmias requiring radiofrequency ablation. Atrial fibrillation (Afib) is a common arrhythmia in EA patients, and results in debilitating symptoms that often require surgical treatment. This is a follow-up report of 2 patients with EA undergoing radiofrequency ablation for Afib...
November 29, 2017: Cardiology
https://www.readbyqxmd.com/read/29182748/phrenic-nerve-injury-during-right-inferior-pulmonary-vein-ablation-with-the-second-generation-cryoballoon-clinical-procedural-and-anatomical-characteristics
#17
Juan-Pablo Abugattas, Carlo de Asmundis, Saverio Iacopino, Francesca Salghetti, Ken Takarada, Hugo-Enrique Coutiño, Erwin Ströker, Valentina De Regibus, Yves de Greef, Pedro Brugada, Juan Sieira, Gian-Battista Chierchia
Aims: There is still sparse information regarding phrenic nerve injury (PNI) during ablation of the right inferior pulmonary vein (RIPV) by means of the second-generation cryoballoon advance (CB-A). The aim of this study was to describe the procedural, anatomical, and clinical characteristics of patients who experienced PNI during the RIPV ablation. Methods and results: Consecutive patients who had undergone pulmonary vein isolation (PVI) using CB-A and suffered PNI during RIPV ablation were retrospectively included in our study...
November 22, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29178497/how-to-perform-posterior-wall-isolation-in-catheter-ablation-for-atrial-fibrillation
#18
Hariharan Sugumar, Stuart P Thomas, Sandeep Prabhu, Aleksandr Voskoboinik, Peter M Kistler
Catheter ablation (CA) has become standard of care in patients with symptomatic atrial fibrillation (AF). Although there have been significant advances in our understanding and technology, a substantial proportion of patients have ongoing AF requiring repeat procedures. Pulmonary vein isolation (PVI) is the cornerstone of AF ablation; however, it is less effective in patients with persistent as opposed to paroxysmal atrial fibrillation (PAF). Left atrial posterior wall isolation (PWI) is commonly performed as an adjunct to PVI in patients with persistent AF with non-randomized studies showing improved outcomes...
November 27, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29177475/individually-tailored-vs-standardized-substrate-modification-during-radiofrequency-catheter-ablation-for-atrial-fibrillation-a-randomized-study
#19
Simon Kircher, Arash Arya, David Altmann, Sascha Rolf, Andreas Bollmann, Philipp Sommer, Nikolaos Dagres, Sergio Richter, Ole-A Breithardt, Borislav Dinov, Daniela Husser, Charlotte Eitel, Thomas Gaspar, Christopher Piorkowski, Gerhard Hindricks
Aims: This randomized single-centre study sought to compare the efficacy and safety of pulmonary vein isolation (PVI) plus voltage-guided ablation vs. PVI with or without linear ablation depending on the type of atrial fibrillation (AF). Methods and results: Overall, 124 ablation-naive patients with paroxysmal or persistent AF were randomized to PVI with (persistent AF) or without (paroxysmal AF) additional linear ablation (control group) vs. PVI plus ablation of low-voltage areas (LVAs) irrespective of AF type...
November 21, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29173075/evaluation-of-plasma-growth-factors-vegf-pdgf-egf-ang1-and-ang2-in-patients-with-varicose-veins-before-and-after-treatment-with-endovenous-laser-ablation
#20
Nabil A Al-Zoubi, Rami J Yaghan, Tagleb S Mazahreh, Emad M Hijazi, Ahmad Alqudah, Yasmin N Owaisy, Shadi Hamouri, Nawaf J Al-Shatnawi
OBJECTIVE: To measure pre- and postoperative plasma concentrations of growth factors (VEGF, PDGF, EGF, ANG1, and ANG2) in patients with primary lower limb varicose veins (VVs) treated with endovenous laser ablation (EVLA). BACKGROUND: Many studies have explored the potential relationship between primary VVs and growth factors. No previous studies were done for patients treated with EVLA. MATERIALS AND METHODS: Blood samples were obtained from 30 patients with primary VVs undergoing treatment with EVLA before and 1 week after treatment...
November 27, 2017: Photomedicine and Laser Surgery
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