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https://www.readbyqxmd.com/read/29732601/longitudinal-ultrasound-curriculum-incorporation-at-west-virginia-university-school-of-medicine-a-description-and-graduating-students-perceptions
#1
Joseph Minardi, Holly Ressetar, Theresa Foreman, Kristen Craig, Melinda Sharon, John Bassler, Stephen Davis, Anthony Machi, Scott Cottrell, Nicolas Denne, Norman Ferrari, Kenneth Landreth, Bruce Palmer, Gregory Schaefer, Robert Tallaksen, David Wilks, Dorian Williams
OBJECTIVES: Sonography is a clinical tool being incorporated in multiple medical specialties with evidence of improved patient care and cost. Some schools have begun implementing ultrasound curricula. We hope to build upon that foundation and provide another potential framework of incorporation. There are several barriers, including curricular space, equipment and physical space, adequate faculty, and performing assessment. METHODS: At West Virginia University, we began a longitudinal ultrasound curriculum in 2012 with incorporation of didactic and practical sessions into gross anatomy, our systems-based second-year curriculum, physical diagnosis course, and clinical rotations...
May 6, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29725970/predominant-improvement-of-alpha-cell-function-after-steroid-therapy-in-a-patient-with-autoimmune-pancreatitis-case-report
#2
Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-Ichi Murata, Takashi Akamizu
INTRODUCTION: Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic endocrine function is still controversial. We present a case of AIP, focusing on pancreatic endocrine function after steroid therapy. CASE REPORT: The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling...
May 3, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29700047/multicentric-experience-in-distal-to-proximal-revascularization-of-tandem-occlusion-stroke-related-to-internal-carotid-artery-dissection
#3
G Marnat, M Bühlmann, O F Eker, J Gralla, P Machi, U Fischer, C Riquelme, M Arnold, A Bonafé, S Jung, V Costalat, P Mordasini
BACKGROUND AND PURPOSE: Internal carotid dissection is a frequent cause of ischemic stroke in young adults. It may cause tandem occlusions in which cervical carotid obstruction is associated with intracranial proximal vessel occlusion. To date, no consensus has emerged concerning endovascular treatment strategy. Our aim was to evaluate our endovascular "distal-to-proximal" strategy in the treatment of this stroke subtype in the first large multicentric cohort. MATERIALS AND METHODS: Prospectively managed stroke data bases from 2 separate centers were retrospectively studied between 2009 and 2014 for records of tandem occlusions related to internal carotid dissection...
April 26, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29625154/experimental-evaluation-of-the-neva-tm-thrombectomy-device-a-novel-stent-retriever-conceived-to-improve-efficacy-of-organized-clot-removal
#4
Paolo Machi, Arthur J Ulm, Gianmarco Bernava, Olivier Brina, Karl Olof Lovblad, Franck Jourdan
BACKGROUND AND PURPOSE: Stent retrievers are recognized as the most effective devices for intracranial thrombectomy. Although highly effective, such devices fail in clot removal when the brain vessel occlusion is due to organized, firm clots. The mechanism of failure is that during the retrieval, devices remain compressed by the organized clot and slide between it and the vessel wall without any removal effect. The aim of the current study is to present the preclinical evaluation of the Neva™ device, a novel stent retriever designed to improve the incorporation and removal of organized thrombi...
April 3, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29625141/optimal-cutoff-values-of-fasting-plasma-glucose-fpg-variability-for-detecting-retinopathy-and-the-threshold-of-fpg-levels-for-predicting-the-risk-of-retinopathy-in-type-2-diabetes-a-longitudinal-study-over-27-years
#5
Toshiko Takao, Kaori Inoue, Machi Suka, Hiroyuki Yanagisawa, Yasuhiko Iwamoto
AIMS: To determine the cutoff values of fasting plasma glucose (FPG) variability for detecting retinopathy and examine the threshold of FPG levels for predicting retinopathy incidence in type 2 diabetes. METHODS: Subjects comprised 170 patients with type 2 diabetes who had no retinopathy at their first visit, and continuously visited thereafter for 27 years. Retinopathy was evaluated by ophthalmologists at least annually. RESULTS: 114 patients developed retinopathy...
April 3, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29555642/protective-roles-of-interferon-%C3%AE-in-cardiac-hypertrophy-induced-by-sustained-pressure-overload
#6
Akihiko Kimura, Yuko Ishida, Machi Furuta, Mizuho Nosaka, Yumi Kuninaka, Akira Taruya, Naofumi Mukaida, Toshikazu Kondo
BACKGROUND: A clear understanding of the molecular mechanisms underlying hemodynamic stress-initiated cardiac hypertrophy is important for preventing heart failure. Interferon-γ (IFN-γ) has been suggested to play crucial roles in various diseases other than immunological disorders by modulating the expression of myriad genes. However, the involvement of IFN-γ in the pathogenesis of cardiac hypertrophy still remains unclear. METHODS AND RESULTS: In order to elucidate the roles of IFN-γ in pressure overload-induced cardiac pathology, we subjected Balb/c wild-type (WT) or IFN-γ-deficient ( Ifng -/- ) mice to transverse aortic constriction (TAC)...
March 19, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29451659/environmental-factors-can-influence-dengue-reported-cases
#7
Marco Antonio F Carneiro, Beatriz da C A Alves, Flávia de Sousa Gehrke, José Nuno Domingues, Nelson Sá, Susana Paixão, João Figueiredo, Ana Ferreira, Cleonice Almeida, Amaury Machi, Eriane Savóia, Vânia Nascimento, Fernando Fonseca
INTRODUCTION: Global climate changes directly affect the natural environment and contribute to an increase in the transmission of diseases by vectors. Among these diseases, dengue is at the top of the list. The aim of our study was to understand the consequences of temporal variability of air temperature in the occurrence of dengue in an area comprising seven municipalities of the Greater São Paulo. METHOD: Characterization of a temporal trend of the disease in the region between 2010 and 2013 was performed through analysis of the notified number of dengue cases over this period...
November 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29449944/dexmedetomidine-use-during-epiduroscopy-reduces-fentanyl-use-and-postoperative-nausea-and-vomiting-a-single-center-retrospective-study
#8
Takashi Suzuki, Ryota Inokuchi, Kazuo Hanaoka, Machi Suka, Hiroyuki Yanagisawa
Objectives: Minimally invasive epiduroscopy has recently been reported as an effective treatment procedure for chronic and intractable low back pain. However, no study has determined safe anesthetics for monitored anesthesia care during epiduroscopy. We aimed to compare and evaluate conventional monitored anesthesia care drugs with dexmedetomidine. Methods: A retrospective study including all patients who underwent epiduroscopy at the JR Tokyo General Hospital from April 2011 to March 2016 was designed...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29437981/second-generation-hydrogel-coils-for-the-endovascular-treatment-of-intracranial-aneurysms-a-randomized-controlled-trial
#9
RANDOMIZED CONTROLLED TRIAL
Christian A Taschner, René Chapot, Vincent Costalat, Paolo Machi, Patrick Courthéoux, Xavier Barreau, Jérôme Berge, Laurent Pierot, Krzysztof Kadziolka, Betty Jean, Raphaël Blanc, Alessandra Biondi, Hervé Brunel, Sophie Gallas, Ansgar Berlis, Denis Herbreteau, Joachim Berkefeld, Horst Urbach, Samer Elsheikh, Jens Fiehler, Hubert Desal, Erika Graf, Alain Bonafé
BACKGROUND AND PURPOSE: Endovascular embolization of intracranial aneurysms with hydrogel-coated coils lowers the risk of major recurrence, but technical limitations (coil stiffness and time restriction for placement) have prevented their wider clinical use. We aimed to assess the efficacy of softer, second-generation hydrogel coils. METHODS: A randomized controlled trial was conducted at 22 centers in France and Germany. Patients aged 18 to 75 years with untreated ruptured or unruptured intracranial aneurysms measuring 4 to 12 mm in diameter were eligible and randomized (1:1 using a web-based system, stratified by rupture status) to coiling with either second-generation hydrogel coils or bare platinum coils...
March 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29410371/trans-venous-embolization-of-a-basal-ganglia-ruptured-arteriovenous-malformation-with-open-surgical-arterial-control-a-hybrid-technique
#10
Zsolt Kulcsár, Paolo Machi, Karl Schaller, Karl Olof Lovblad, Philippe Bijlenga
Treatment of ruptured deep-seated arteriovenous malformations is challenging and associated with elevated risks. This is due to the proximity or involvement of critical brain structures and the specifically fine and delicate angioarchitecture of these lesions, making both endovascular and surgical access technically complicated. We present the advantages of a true combined, open surgical and endovascular transvenous approach in a hybrid operating room. The technique may overcome in part the difficulties and may improve safety and risk related concerns...
February 2, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29410105/the-catch-mini-stent-retriever-for-mechanical-thrombectomy-in-distal-intracranial-occlusions
#11
Jeremy Hofmeister, Zsolt Kulcsar, Gianmarco Bernava, Alain Pellaton, Hasan Yilmaz, Gorislav Erceg, Maria Isabel Vargas, Karl-Olof Lovblad, Paolo Machi
OBJECTIVE: Mechanical thrombectomy (MTB) is a treatment of reference for acute ischemic stroke due to large brain vessel occlusion but some concerns remain about its use in small distal branches. In the present study, we assessed the efficacy and the safety of distal MTB using the Catch Mini (CM) stent retriever. METHODS: We retrospectively reviewed a prospectively maintained database of all consecutive patients who underwent MTB for a distal intracranial occlusion with the Catch Mini device at our hospital...
February 1, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29401710/dietary-iron-supplementation-alters-hepatic-inflammation-in-a-rat-model-of-nonalcoholic-steatohepatitis
#12
Machi Atarashi, Takeshi Izawa, Rena Miyagi, Shoko Ohji, Ai Hashimoto, Mitsuru Kuwamura, Jyoji Yamate
Nonalcoholic fatty liver disease (NAFLD) is now the most common liver disease in the world. NAFLD can progress to nonalcoholic steatohepatitis (NASH), cirrhosis and eventually hepatocellular carcinoma. Acquired hepatic iron overload is seen in a number of patients with NAFLD; however, its significance in the pathology of NAFLD is still debated. Here, we investigated the role of dietary iron supplementation in experimental steatohepatitis in rats. Rats were fed a control, high-fat (HF), high-fat high-iron (HFHI) and high-iron (HI) diet for 30 weeks...
February 4, 2018: Nutrients
https://www.readbyqxmd.com/read/29382772/outcome-of-transarterial-treatment-of-dural-arteriovenous-fistulas-with-direct-or-indirect-cortical-venous-drainage
#13
Daniel Mantilla, Marine Le Corre, Federico Cagnazzo, Gregory Gascou, Omer Eker, Paolo Machi, Carlos Riquelme, Cyril Dargazanli, Vincent Costalat, Alain Bonafe, Pierre-Henri Lefevre
BACKGROUND AND PURPOSE: Transarterial Onyx embolization is an effective treatment for patients with intracranial dural arteriovenous fistula (DAVF). A study was performed to determine whether the clinical and radiological outcomes after transarterial Onyx treatment were affected by the type of cortical venous drainage (direct vs indirect) of high-grade DAVF. MATERIALS AND METHODS: Between May 2006 and December 2014, demographic data, clinical presentation, angiographic characteristics, and treatment-related outcomes were collected for 54 patients divided into two groups (intracranial DAVF with direct and indirect cortical venous drainage)...
January 30, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29370013/differences-in-work-related-adverse-events-by-sex-and-industry-in-cases-involving-compensation-for-mental-disorders-and-suicide-in-japan-from-2010-to-2014
#14
Takashi Yamauchi, Takeshi Sasaki, Toru Yoshikawa, Shun Matsumoto, Masaya Takahashi, Machi Suka, Hiroyuki Yanagisawa
OBJECTIVE: This study aimed to clarify whether work-related adverse events in cases involving compensation for mental disorders and suicide differ by sex and industry using a database containing all relevant cases reported from 2010 to 2014 in Japan. METHODS: A total of 1362 eligible cases involving compensation for mental disorders (422 females and 940 males) were analyzed. RESULTS: Among males, 55.7% of cases were attributed to "long working hours...
April 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29277864/assembly-annotation-and-comparative-genomics-in-patric-the-all-bacterial-bioinformatics-resource-center
#15
Alice R Wattam, Thomas Brettin, James J Davis, Svetlana Gerdes, Ronald Kenyon, Dustin Machi, Chunhong Mao, Robert Olson, Ross Overbeek, Gordon D Pusch, Maulik P Shukla, Rick Stevens, Veronika Vonstein, Andrew Warren, Fangfang Xia, Hyunseung Yoo
In the "big data" era, research biologists are faced with analyzing new types that usually require some level of computational expertise. A number of programs and pipelines exist, but acquiring the expertise to run them, and then understanding the output can be a challenge.The Pathosystems Resource Integration Center (PATRIC, www.patricbrc.org ) has created an end-to-end analysis platform that allows researchers to take their raw reads, assemble a genome, annotate it, and then use a suite of user-friendly tools to compare it to any public data that is available in the repository...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29209882/hemodynamics-of-focal-versus-global-growth-of-small-cerebral-aneurysms
#16
Paolo Machi, Rafik Ouared, Olivier Brina, Pierre Bouillot, Hasan Yilmaz, Maria I Vargas, Renato Gondar, Philippe Bijlenga, Karl O Lovblad, Zsolt Kulcsár
BACKGROUND AND PURPOSE: Hemodynamics play a driving role in the life cycle of brain aneurysms from initiation through growth until eventual rupture. The specific factors behind aneurysm growth, especially in small aneurysms, are not well elucidated. The goal of this study was to differentiate focal versus general growth and to analyze the hemodynamic microenvironment at the sites of enlargement in small cerebral aneurysms. MATERIALS AND METHODS: Small aneurysms showing growth during follow-up were identified from our prospective aneurysm database...
December 5, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/29175829/safety-and-effectiveness-of-the-low-profile-visualized-intraluminal-support-lvis-and-lvis-jr-devices-in-the-endovascular-treatment-of-intracranial-aneurysms-results-of-the-trail-multicenter-observational-study
#17
Christina Iosif, Michel Piotin, Suzana Saleme, Xavier Barreau, Jacques Sedat, Yves Chau, Nader Sourour, Mohamed Aggour, Herve Brunel, Alain Bonafe, Paolo Machi, Carlos Riquelme, Vincent Costalat, Laurent Pierot, Raphael Blanc, Charbel Mounayer
BACKGROUND AND PURPOSE: To evaluate the safety and effectiveness of the low-profile braided intracranial stents called the Low Profile Visualized Intraluminal Support (LVIS) devices for stent-assisted coil embolization of wide-necked intracranial aneurysms. MATERIALS AND METHODS: This was a prospective, multicenter, observational study of unruptured and ruptured intracranial aneurysms treated with the LVIS devices. Imaging and clinical data were independently analyzed respectively by CoreLab and Clinical Event Committee...
November 24, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29165165/perceived-effectiveness-rating-scales-applied-to-insomnia-help-seeking-messages-for-middle-aged-japanese-people-a-validity-and-reliability-study
#18
Machi Suka, Takashi Yamauchi, Hiroyuki Yanagisawa
BACKGROUND: Communicating health messages is an important way to influence people's behaviors towards health issues. Providers need to incorporate audience's perspective to design more persuasive messages. This study aimed to develop rating scales for measuring audience's perception of effectiveness of health messages in Japanese people. METHODS: The comprehensibility scale including five items and the persuasiveness scale including seven items were designed based on literature review...
September 29, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29139579/topical-adjuvants-incompletely-remove-adherent-staphylococcus-aureus-from-implant-materials
#19
Emily P Ernest, Anthony S Machi, Brock A Karolcik, Paul R LaSala, Matthew J Dietz
Adjuvant treatments including Betadine, Dakin's solution (sodium hypochlorite), or hydrogen peroxide (H2 O2 ) have been attempted to eradicate prosthetic joint infection caused by biofilm or intracellular bacteria. The purpose of this study was to evaluate the in vitro abilities of chemical adjuvants to decrease Staphylococcus aureus (S. aureus) biofilm presence on orthopaedic implant grade materials, including titanium, stainless steel, and cobalt chrome. S. aureus biofilms were grown for 48 h and evaluated for baseline colony forming units/centimeter squared (CFU/cm2 ) and compared to treatments with Betadine, Dakin's solution, H2 O2 , or 1% chlorine dioxide (ClO2 )...
November 15, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29051203/anterior-circulation-acute-ischemic-stroke-associated-with-atherosclerotic-lesions-of-the-cervical-ica-a-nosologic-entity-apart
#20
O F Eker, P Panni, C Dargazanli, G Marnat, C Arquizan, P Machi, I Mourand, G Gascou, E Le Bars, V Costalat, A Bonafé
BACKGROUND AND PURPOSE: Mechanical thrombectomy for patients with acute ischemic stroke with tandem occlusions has been shown to present varying reperfusion successes and clinical outcomes. However, the heterogeneity of tandem occlusion etiology has been strongly neglected in previous studies. We retrospectively investigated patients with acute ischemic stroke atherothrombotic tandem occlusion. MATERIALS AND METHODS: All consecutive patients with acute ischemic stroke with atherothrombotic tandem occlusions treated with mechanical thrombectomy in our center between September 2009 and April 2015 were analyzed...
November 2017: AJNR. American Journal of Neuroradiology
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