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nephrotic syndrone

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January 10, 1965: Nihon Naika Gakkai Zasshi. the Journal of the Japanese Society of Internal Medicine
P Fernández-Llama, P Andrews, C A Ecelbarger, S Nielsen, M Knepper
BACKGROUND: Several pathophysiological states associated with deranged water balance are associated with altered expression and/or intracellular distribution of aquaporin water channels. The possible role of dysregulation of thick ascending limb NaCl transporters, which are responsible for countercurrent multiplication in the kidney, has not been evaluated. METHODS: Semiquantitative immunoblotting and immunocytochemistry were carried out in the kidneys of rat with adriamycin-induced nephrotic syndrome and in vehicle-injected control rats...
July 1998: Kidney International
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