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Hyponatremia case report

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https://www.readbyqxmd.com/read/29896051/-case-report-osmotic-demyelination-syndrome-in-an-adolescent-with-neuromyelitis-optica
#1
Sarah Kariv, Kathleen Bateman
A 17-year-old girl presented with intractable vomiting due to area postrema involvement in the first presentation of seronegative neuromyelitis optica (NMO). During the course of her illness, she developed mild hyponatremia, and magnetic resonance imaging revealed abnormalities consistent with the co-occurrence of osmotic demyelination syndrome (ODS). This combination of imaging features is novel, and this case expands the spectrum of brain abnormalities seen in NMO and NMO spectrum disorders. It was suspected that NMO may predispose to ODS by causing astrocyte dysfunction involving aquaporin 4 water channels, which are implicated in both conditions...
May 2018: International Journal of MS Care
https://www.readbyqxmd.com/read/29877286/legionella-pneumonia-complicated-with-acquired-fanconi-syndrome-a-case-report
#2
Ryo Koda, Ryo Itoh, Masafumi Tsuchida, Kazumasa Ohashi, Noriaki Iino, Toshinori Takada, Ichiei Narita
Legionella pneumonia is occasionally accompanied by renal complications; however, the cause of this remains unknown. We herein report a 70-year-old Japanese man with Legionella pneumonia who presented with hyponatremia, hypophosphatemia, and hypouricemia. The levels of urinary β2-microglobulin and N-acetyl-β-D-glucosaminidase were remarkably high, indicating severe renal tubular damage. The presence of glycosuria and aminoaciduria as well as increased fractional excretion of uric acid and decreased tubular reabsorption of phosphate indicated that the patient's condition was complicated with Fanconi syndrome...
June 6, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29863435/a-case-series-study-of-hypopituitarism-in-older-patients-with-and-without-gastrointestinal-symptoms
#3
Xiaowei Li, Hang Yang, Zhijun Duan, Qingyong Chang, Xiaoting Wei, Changjin Li, Ying Ba, Jianling Du
OBJECTIVES: Some older individuals who present with gastrointestinal symptoms as their chief complaint were ultimately diagnosed with hypopituitarism instead of gastrointestinal diseases. The aim of this study was to find the characteristics of biochemical indicators in these patients so as to reduce early misdiagnosis. METHODS: We conducted a retrospective review of 45 patients with hypopituitarism who were at least 60 years of age. Two groups were included: group of hypopituitarism patients with gastrointestinal symptoms (Group G) included 23 patients with gastrointestinal symptoms and group of hypopituitarism patients without gastrointestinal symptoms (Group N) included 22 patients without these symptoms...
June 4, 2018: Postgraduate Medicine
https://www.readbyqxmd.com/read/29843084/chronic-hyponatremia-why-care-a-case-report
#4
Sarah Seberg Diemar, Anne-Sophie Sejling, Niklas Rye Jørgensen, Noémi Becser Andersen
No abstract text is available yet for this article.
May 21, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29796276/successful-treatment-by-tolvaptan-of-the-syndrome-of-inappropriate-antidiuretic-hormone-secretion-that-may-be-associated-with-chemotherapy-induced-tumour-lysis-in-a-patient-with-small-cell-lung-carcinoma
#5
Koichi Miyashita, Shun Matsuura, Hyogo Naoi, Masaru Tsukui, Naoki Koshimizu, Takafumi Suda
Here, we report the case of a patient with small-cell lung carcinoma (SCLC) who developed the syndrome of inappropriate antidiuretic hormone secretion (SIADH). This syndrome may be associated with chemotherapy-induced tumour lysis. Our patient was successfully treated with tolvaptan. A 70-year-old man was diagnosed with SCLC and was treated with carboplatin and etoposide. Episodes of hyponatremia occurred after every four cycles of chemotherapy that achieved tumour reduction; however, the hyponatremia was improved by temporary administration of tolvaptan...
April 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29775155/long-term-surgical-outcomes-following-transsphenoidal-surgery-in-patients-with-rathke-s-cleft-cysts
#6
Michelle Lin, Michelle A Wedemeyer, Daniel Bradley, Daniel A Donoho, Vance L Fredrickson, Martin H Weiss, John D Carmichael, Gabriel Zada
OBJECTIVE Rathke's cleft cysts (RCCs) are benign epithelial lesions of the sellar region typically treated via a transsphenoidal approach with cyst fenestration and drainage. At present, there is limited evidence to guide patient selection for operative treatment. Furthermore, there is minimal literature describing factors contributing to cyst recurrence. METHODS The authors conducted a retrospective analysis of 109 consecutive cases of pathology-confirmed RCCs treated via a transsphenoidal approach at a single center from 1995 to 2016...
May 18, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29773358/-antidepressive-agents-and-hyponatremia-a-literature-review-and-a-case-non-case-study-in-the-french-pharmacovigilance-database
#7
Michaël Rochoy, Christina Zakhem-Stachera, Johana Béné, Christophe Berkhout, Sophie Gautier
OBJECTIVE: Most antidepressants have been associated with a risk of hyponatremia in the literature. This effect is not always reported in monographs. The aim of our study was to clarify the difference of increased risk of hyponatremia among various antidepressants. METHODS: Retrospective study of such cases/non-cases from observations recorded in the French national pharmacovigilance between 01/01/2004 and 31/12/2013. We studied all antidepressants marketed in 2014 in France, with a positive control (haloperidol) and a negative one (amoxicillin)...
March 1, 2018: Thérapie
https://www.readbyqxmd.com/read/29720096/celiac-crisis-a-rare-and-profound-presentation-of-celiac-disease-a-case-report
#8
Elizabeth Ann Forrest, Mark Wong, Srinivasa Nama, Siddharth Sharma
BACKGROUND: Celiac crisis is a life-threatening manifestation of celiac disease and is rare in adults, with only a handful of cases documented worldwide and mostly in children. CASE PRESENTATION: A profoundly emaciated 43-year-old female presented with profuse diarrhoea, shortness of breath, left leg swelling with ulceration and immobility (Body Mass Index (BMI) = 14.7 kg/m2 ). The patient had normal anion-gap metabolic acidosis (pH = 7.16) with persisting hypokalemia, hyponatremia, hypomagnesemia and hypophosphatemia...
May 2, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29709945/a-case-of-fulminant-type-1-diabetes-mellitus-complicated-with-a-life-threatening-electrolyte-abnormality-and-abnormal-electrocardiogram-findings
#9
Tomoe Kinoshita, Hideaki Kaneto, Fumiko Kawasaki, Takatoshi Anno, Takeyuki Kurihara, Haruki Yamada, Yoshiyuki Oshiro, Naoyuki Miyashita, Niro Okimoto, Kohei Kaku
Fulminant type 1 diabetes mellitus (T1DM) is idiopathic T1DM with the rapid destruction of pancreatic β-cells. We herein report a 48-year-old man who developed fulminant T1DM complicated with a life-threatening electrolyte abnormality and abnormal electrocardiogram findings. He had no remarkable medical history, but one day, he developed general fatigue. His blood glucose level and HbA1c were 806 mg/dL and 6.3%, and his insulin secretion was markedly suppressed. He had ketoacidosis, hyponatremia and hyperkalemia...
April 27, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29703048/tolvaptan-rescue-contrast-induced-acute-kidney-injury-a-case-report
#10
Wei-Chieh Lee, Hsiu-Yu Fang, Chih-Yuan Fang
RATIONALE: Contrast-induced acute kidney injury is one of the most serious adverse effects of contrast media and is related to three distinct but interacting mechanisms: medullary ischemia, formation of reactive oxygen species and direct tubular cell toxicity, especially in the patients with chronic kidney disease. The strategies of treatment, including stabilization of hemodynamic parameters and maintenance of normal fluid and electrolyte balance, were similar to the management of other types of acute kidney injury...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29696555/desmopressin-induced-severe-hyponatremia-with-central-pontine-myelinolysis-a-case-report
#11
Tanzib Hossain, Marya Ghazipura, Vineet Reddy, Pedro J Rivera, Vikramjit Mukherjee
Desmopressin, a synthetic vasopressin analog, is used to treat central diabetes insipidus, hemostatic disorders such as von Willebrand's disease, and nocturnal enuresis. We present the case of a 69-year-old man who developed severe hyponatremia during treatment with intranasal desmopressin at 10 µg twice daily for chronic polyuria and nocturia thought to be due to central diabetes insipidus. After 5 months of therapy, the patient noticed progressive fatigue, anorexia, dizziness, weakness, light-headedness, decreased concentration, and new-onset falls...
April 25, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29693270/uremic-encephalopathy-in-a-rhesus-macaque-macaca-mulatta-a-case-report-and-a-brief-review-of-the-veterinary-literature
#12
REVIEW
Allison Mustonen, Olga Gonzalez, Elda Mendoza, Shyamesh Kumar, Edward J Dick
BACKGROUND: Uremic encephalopathy is uncommon yet is one of the most severe complications of renal failure. We present a case of acute renal failure and associated cerebral and vascular lesions consistent with uremic encephalopathy in a rhesus macaque (Macaca mulatta). METHODS: A 14-year-old, female, specific-pathogen-free rhesus macaque presented in lateral recumbency, obtunded, severely dehydrated, and hypothermic, with severe azotemia, mild hyponatremia, hypokalemia, hypochloremia, increased anion gap, and hypercholesterolemia...
April 25, 2018: Journal of Medical Primatology
https://www.readbyqxmd.com/read/29684948/-successful-treatment-of-peritoneal-dissemination-recurrence-with-axitinib-in-papillary-renal-cell-carcinoma-a-case-report
#13
Junichi Mori, Yuki Nakayama, Tsuyoshi Hiragino, Hideyasu Matsuyama
We report a case of successful treatment of recurrence of peritoneal dissemination with axitinib. A 55-year-old man presented at our hospital with the chief complaint of remarkable abdominal fullness 18 months after right radical nephrectomy, which had been performed at another hospital for the treatment of renal cell carcinoma. The pathological diagnosis was papillary renal cell carcinoma type 1, pT3aN0M0. A large amount of ascites was detected by computed tomography, and recurrence of peritoneal dissemination was diagnosed (ascites cytology : class V)...
February 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29675480/pituitary-dysfunction-from-an-unruptured-ophthalmic-internal-carotid-artery-aneurysm-with-improved-2-year-follow-up-results-a-case-report
#14
Meng Qi, Ming Ye, Meng Li, Peng Zhang
Internal carotid artery (ICA) supraclinoid segment aneurysms extending into the sellar region and leading to pituitary dysfunction are a rare occurrence. To date, long-term follow up of pituitary function 2 years post-treatment has never been reported. Herein, we present a case of pituitary dysfunction due to an unruptured ophthalmic segment internal carotid artery aneurysm and report improved 2-year follow-up results. A 76-year-old male presented with disturbed consciousness due to hyponatremia, which was caused by hypoadrenocorticism resulting from pituitary dysfunction complicated by hypogonadism and hypothyroidism...
2018: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29595672/a-case-report-of-a-man-on-peritoneal-dialysis-having-intractable-hyponatremia
#15
Xu-Jie Zhou, Ying Yang, Tao Su, Jie Dong
RATIONALE: Hyponatremia is one of the most common electrolyte disorders in patients on peritoneal dialysis (PD). It can be associated with severe consequences, higher morbidity and mortality. Therefore, hyponatremia should be assessed and monitored more carefully in these patients. PATIENT CONCERNS: A 55-year-old male PD patient progressively developed intractable hyponatremia was admitted to our hospital. DIAGNOSES: The observation that no significant salt was lost in kidney and PD drainage prompted us to seek the underlying reasons for malnutrition and chronic inflammation...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29582446/molecular-genetic-studies-in-a-case-series-of-isolated-hypoaldosteronism-due-to-biosynthesis-defects-or-aldosterone-resistance
#16
Ihsan Turan, Leman Damla Kotan, Mehmet Tastan, Fatih Gurbuz, Ali Kemal Topaloglu, Bilgin Yuksel
BACKGROUND AND AIM: Hypoaldosteronism is associated with either insufficient aldosterone production or aldosterone resistance (pseudohypoaldosteronism). Patients with aldosterone defects typically present with similar symptoms and findings, which include failure to thrive, vomiting, hyponatremia, hyperkalemia and metabolic acidosis. Accurate diagnosis of these clinical conditions therefore can be challenging. Molecular genetic analyses can help to greatly clarify this complexity. The aim of this study was to obtain an overview of the clinical and genetic characteristics of patients with aldosterone defects due to biosynthesis defects or aldosterone resistance...
March 27, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29564285/a-case-report-of-rapid-onset-hyponatremia-induced-by-low-dose-olanzapine
#17
Sethulakshmi Sreevalsam Anil, Badr Ratnakaran, Nisha Suresh
Hyponatremia has been reported with the use of psychotropic drugs. Olanzapine does not find much mention as a cause of hyponatremia in literature; however, it has been found to be the second most frequently reported atypical antipsychotic to cause it. We report a case of hyponatremia due to syndrome of inappropriate antidiuretic hormone secretion which occurred at a rapid onset following the administration of low-dose olanzapine during inpatient treatment of a patient with bipolar disorder. We would like to highlight our case for the need to be vigil about such fatal side complications apart from metabolic side effects of atypical antipsychotics...
October 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29560008/closed-eye-visualizations-in-the-setting-of-hyponatremia
#18
Travis Peck, Christopher Mercogliano, Eugene York
Purpose: To report a case of closed-eye visualizations and to clarify the different types of hallucinations and their etiologies. Methods: Retrospective case report of a patient with closed-eye visualizations secondary to hyponatremia. Clinical findings, physical exam, laboratory assessment, treatment, and disease course from the patient's hospitalization were used in creating this report. Follow-up data after discharge were also obtained. Results: Closed-eye visualizations were diagnosed as secondary to hyponatremia, as they did not occur with the eyes open, and potential alternate causes were excluded...
2018: Case Reports in Medicine
https://www.readbyqxmd.com/read/29546600/focus-on-neonatal-and-infantile-onset-of-nephrogenic-syndrome-of-inappropriate-antidiuresis-12-years-later
#19
REVIEW
Flaminia Bardanzellu, Maria Cristina Pintus, Valentina Masile, Vassilios Fanos, Maria Antonietta Marcialis
Nephrogenic syndrome of inappropriate antidiuresis (NSIAD), first described in 2005, is a rare genetic X-linked disease, presenting with hyponatremia, hyposmolarity, euvolemia, inappropriately concentrated urine, increased natriuresis, and undetectable or very low arginine-vasopressine (AVP) circulating levels. It can occur in neonates, infants, or later in life. NSIAD must be early recognized and treated to prevent severe hyponatremia, which can show a dangerous impact on neonatal outcome. In fact, it potentially leads to death or, in case of survival, neurologic sequelae...
March 15, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29540223/tongue-fasciculations-with-denervation-pattern-in-osmotic-demyelination-syndrome-a-case-report-of-diagnostic-dilemma
#20
H M M T B Herath, S P Pahalagamage, Sunethra Senanayake
BACKGROUND: The pathogenesis of osmotic demyelination syndrome is not completely understood and usually occurs with severe and prolonged hyponatremia, particularly with rapid correction. It can occur even in normonatremic patients, especially who have risk factors like alcoholism, malnutrition and liver disease. Bilateral tongue fasciculations with denervation pattern in electromyogram is a manifestation of damage to the hypoglossal nucleus or hypoglossal nerves. Tongue fasciculations were reported rarely in some cases of osmotic demyelination syndrome, but the exact mechanism is not explained...
March 14, 2018: BMC Research Notes
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