keyword
https://read.qxmd.com/read/38431543/feasibility-and-early-cosmetic-outcome-of-modified-lateral-intercostal-artery-perforator-flap-after-breast-conservative-surgery
#21
JOURNAL ARTICLE
Islam M Korayem, Rabie Ramadan, Haytham Fayed
BACKGROUND: The lateral intercostal artery perforator (LICAP) flap aims at replacing the excised breast lump with axillary tissue rich blood supply. The purpose of this study is to report the initial results of a modification LICAP flap technique in terms of intraoperative technical feasibility and short-term cosmetic outcomes in the early postoperative period. METHODS: Modified LICAP flap technique was performed on 36 female patients with pathologically proven BC located in the outer half of the breast in the period from June 1, 2021, to April 30, 2022...
March 2, 2024: BMC Surgery
https://read.qxmd.com/read/38431421/oxidized-cellulose-filled-double-thermo-ph-sensitive-hydrogel-for-local-chemo-photothermal-therapy-in-breast-cancer
#22
JOURNAL ARTICLE
Zijian Zhang, Haoran Cui, Xin Wang, Jie Liu, Guangchun Liu, Xin Meng, Song Lin
Lumpectomy plus radiation is a treatment option offering better survival than conventional mastectomy for patients with early-stage breast cancer. However, successive radioactive therapy remains tedious and unsafe with severe adverse reactions and secondary injury. Herein, a composite hydrogel with pH- and photothermal double-sensitive activity is developed via physical crosslinking. The composite hydrogel incorporated with tempo-oxidized cellulose nanofiber (TOCN), polyvinyl alcohol (PVA) and a polydopamine (PDA) coating for photothermal therapy (PTT) triggered in situ release of doxorubicin (DOX) drug was utilized to optimize postoperative strategies of malignant tumors inhibition...
May 15, 2024: Carbohydrate Polymers
https://read.qxmd.com/read/38428963/orbital-and-optic-nerve-sheath-involvement-and-pupil-involving-cranial-nerve-3-palsy-in-giant-cell-arteritis
#23
JOURNAL ARTICLE
Salma A Dawoud, Noor-Us-Sabah Ahmad, Erin M Shriver, Sophia M Chung
Giant cell arteritis (GCA) can present with atypical presentations that are diagnostically challenging. An 84-year-old woman with a history of breast adenocarcinoma treated with lumpectomy and radiation 2 years prior presented with a seizure-like episode.
March 1, 2024: Journal of Rheumatology
https://read.qxmd.com/read/38417817/a-case-of-necrotizing-fasciitis-of-the-breast-following-lumpectomy-and-oncoplastic-closure
#24
JOURNAL ARTICLE
Lauren E Berger, Daisy L Spoer, Samuel S Huffman, Eleanor Drew, Ian T Greenwalt, Kenneth L Fan
BACKGROUND: NF is a life-threatening soft tissue infection that most commonly occurs in the lower extremity. While presenting symptoms such as erythema, severe pain, sepsis, and wound crepitation are well documented, diagnosis of NF of the breast often is obscured by a low clinical index of suspicion due to its relative rarity as well as by the breast parenchyma that physically separates the underlying fascia and overlying skin. Several risk factors have previously been identified, such as underlying infection, diabetes, advanced age, and immunosuppression...
January 2024: Wounds: a Compendium of Clinical Research and Practice
https://read.qxmd.com/read/38416938/ethanol-sclerotherapy-for-postoperative-seroma-of-the-breast-and-axilla
#25
JOURNAL ARTICLE
Camron B Smith, Jay A Baker, Sora C Yoon, Dorothy A Lowell, Lars Grimm
OBJECTIVE: Evaluate the effectiveness of alcohol sclerotherapy in postoperative breast and axillary seromas. METHODS: This was an IRB-approved retrospective review of consecutive patients from 2017 to 2021. The procedure involves aspiration of seroma fluid, injection of ethanol for 15 to 30 minutes, and then aspiration of the injected ethanol. Following review of the medical record, patient and procedure data were recorded. Success was defined as no recurrence of seroma...
March 20, 2023: Journal of breast imaging
https://read.qxmd.com/read/38405107/does-nipple-ward-positive-margin-contribute-to-a-higher-rate-of-re-excision-procedures-after-a-lumpectomy-with-pathology-confirmed-positive-margins-a-retrospective-study
#26
JOURNAL ARTICLE
Fardeen Bhimani, Sophie Lin, Maureen McEvoy, Arianna Cavalli, Liane Obaid, Yu Chen, Anjuli Gupta, Jessica Pastoriza, Areej Shihabi, Sheldon Feldman
BACKGROUND: Positive margins on lumpectomy specimens are associated with a twofold increased risk of local breast tumor recurrence. Prior literature has demonstrated various techniques and modalities for assessing margin status to reduce re-excision rates. However, there is paucity of literature analyzing which margin contributes to the highest re-excision rates. Therefore, the primary aim of the study was to investigate whether the nipple-ward margins resulted in a higher rate of re-excision in our patient population...
2024: Breast Cancer: Targets and Therapy
https://read.qxmd.com/read/38396024/lumpectomy-without-radiation-for-ductal-carcinoma-in-situ-of-the-breast-20-year-results-from-the-ecog-acrin-e5194-study
#27
JOURNAL ARTICLE
Jean L Wright, Robert Gray, Habib Rahbar, Christopher E Comstock, Judy A Tjoe, Sunil Badve, Abram Recht, Joseph A Sparano, Nancy E Davidson, Antonio C Wolff
We report the 20-year rate of ipsilateral breast event (IBE) for patients with ductal carcinoma in situ (DCIS) treated with lumpectomy without radiation on a non-randomized prospective clinical trial. Patients were enrolled in cohort 1: low- or intermediate-grade DCIS, size ≤ 2.5 cm (n = 561); or cohort 2: high-grade DCIS, size ≤ 1 cm (n = 104). The Kaplan-Meier method was used to estimate time-to-event distributions. Cox proportional hazard methods were used to estimate hazard ratios (HRs) and tests for significance for event times...
February 24, 2024: NPJ Breast Cancer
https://read.qxmd.com/read/38387423/machine-learning-analysis-of-online-patient-questions-regarding-breast-reconstruction
#28
JOURNAL ARTICLE
Nicholas C Oleck, Hani I Naga, Mehdi S Lemdani, Christopher C Tseng, Joseph S Weisberger, Roger W Cason, Brett T Phillips
BACKGROUND: Social media has become a dominant educational resource for breast reconstruction patients. Rather than passively consuming information, patients interact directly with other users and healthcare professionals. While online information for breast reconstruction has been analyzed previously, a robust analysis of patient questions on online forums has not been conducted. In this study, the authors used a machine learning approach to analyze and categorize online patient questions regarding breast reconstruction...
February 1, 2024: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://read.qxmd.com/read/38384226/-development-and-clinical-application-of-multifunctional-inflation-free-lumpectomy-aid
#29
JOURNAL ARTICLE
Mengxiang Qiao, Gongsheng Jin, Xianfu Liu, Yansong Chen, Xiaojing Zhang, Hao Zhang, Yanfeng Sun, Yuqing Chen, Ru Bai
To investigate the value of self-developed air-free laparoscopic auxiliary instruments in the clinical application of thyroid diseases. The clinical data of 70 transaxillary and 45 transareolar air-free laparoscopic surgeries for thyroid cancer and 40 conventional open surgeries were retrospectively compared. The transaxillary and transareolar laparoscopic groups had significantly longer operative times than the open group, while the postoperative satisfaction was higher in the endoscopic group than in the open group...
January 30, 2024: Zhongguo Yi Liao Qi Xie za Zhi, Chinese Journal of Medical Instrumentation
https://read.qxmd.com/read/38376294/perceived-stress-anxiety-and-depression-in-women-with-breast-cancer-cibc-study
#30
JOURNAL ARTICLE
Zamaneh Vafaei, Jamshid Najafian, Masood Shekarchizadeh, Noushin Mohammadifard, Samaneh Mostafavi, Hamidreza Roohafza, Ali Darakhshandeh, Mohammadreza Khosravifarsani, Farzaneh Ashraf, Mehran Sharif, Mohammad Hassan Emami, Shaghayegh Haghjooy Javanmard, Razieh Hassannejad, Mohammad Reza Maracy, Nizal Sarrafzadegan
BACKGROUND: Many breast cancer (BC) patients experience psychological reactions and may have psychiatric morbidities, especially anxiety and depressive disorders. The aim of this study was to evaluate perceived stress and factors affecting this stress in women with BC in Isfahan. MATERIAL AND METHODS: This analytical cross-sectional study was carried out among 197 females with BC who were newly diagnosed and referred to Isfahan Cardio-Oncology Clinic. Stress was measured by the Perceived Stress Scale Standard questionnaire...
October 1, 2023: Journal of Cancer Research and Therapeutics
https://read.qxmd.com/read/38368764/interactive-multidisciplinary-pilot-workshop-to-improve-medical-student-perception-of-and-interest-in-breast-surgical-oncology
#31
JOURNAL ARTICLE
Amani Raheel, Shreeya Dalla, Jalee Birney, Allison M Aripoli, Meredith Collins, Kelsey E Larson, Jamie L Wagner, Christa R Balanoff, Jordan Baker, Lynn Chollet-Hinton, Lyndsey J Kilgore
BACKGROUND: Exposure to breast surgical oncology (BSO) and the multidisciplinary management of patients with breast cancer is limited in medical school. The purpose of this study was to assess changes in student perceptions of BSO as a career following an interactive multidisciplinary workshop. METHODS: Pre-clinical medical students participated in a multidisciplinary, hands-on workshop, composed of breast radiology (BR), breast surgical oncology (BSO) and breast plastic reconstructive surgery (B-PRS)...
February 9, 2024: Breast: Official Journal of the European Society of Mastology
https://read.qxmd.com/read/38368667/ductal-carcinoma-in-situ-and-invasive-carcinoma-originating-in-a-fibroadenoma-with-concurrent-benign-phyllodes-tumor-a-case-report
#32
Afaq Ahmad, Erum Najeeb, Muhammad Burhan Ul Haq, Humaira Bashir, Muhammad Uzair, Nadira Mamoon
INTRODUCTION AND IMPORTANCE: This case report presents a rare occurrence of multiple bilateral breast fibroadenomas, one evolving into ductal carcinoma in situ (DCIS) and invasive carcinoma, occurring simultaneously with a benign phyllodes tumor in the same breast. The importance of this case lies in emphasizing the crucial need for surveillance in patients with a long history of fibroadenomas and the necessity to investigate any rapid change in the size of fibroadenoma. CASE PRESENTATION: A 35-year-old multiparous female with a 17 year history of bilateral multiple breast lumps presented with recent onset of right breast pain and yellowish nipple discharge...
December 24, 2023: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38364950/are-we-missing-acute-toxicities-associated-with-hypofractionated-breast-irradiation-a-report-from-a-large-multi-center-cohort-study
#33
JOURNAL ARTICLE
H Beydoun, K A Griffith, R Jagsi, J W Burmeister, J M Moran, F A Vicini, J A Hayman, P Paximadis, T P Boike, E M Walker, L J Pierce, M M Dominello
PURPOSE/OBJECTIVE(S): The efficacy and long-term safety of hypofractionated whole breast irradiation (HF-WBI) has been established through multiple randomized trials, yet data about acute toxicities remains more limited. Since 2013, our group has prospectively collected acute toxicity data from weekly treatment evaluations and additional assessment after completion. In 2016, we intentionally shifted the post-treatment assessment follow-up (f/u) visit from 1 month to 2 weeks in order to evaluate for missed acute toxicity occurring in that immediate post-treatment window...
February 14, 2024: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/38348460/oncoplastic-breast-reconstruction-in-morbidly-obese-patients-an-acceptable-practice
#34
JOURNAL ARTICLE
Grey W Fortenbery, Lauren Todd, Niaman Nazir, Shreeya Dalla, Meredith Collins
BACKGROUND: Breast cancer is the most common noncutaneous malignancy amongst women. Lumpectomy with adjuvant radiation is a mainstay of surgical treatment. Oncoplastic breast reconstruction reduces the resultant breast deformity. Obesity is a risk factor for the development of complications after breast reconstruction. This study's purpose was to determine if oncoplastic breast reconstruction is a safe procedure in obese patients. METHODS: A single institution retrospective chart review was performed on women undergoing oncoplastic breast reduction from 2009 to 2021...
February 2024: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38345725/exploration-of-tumor-size-measurement-methods-in-preoperative-breast-cancer-assessment-using-whole-body-silicon-photomultiplier-pet-feasibility-and-first-results
#35
JOURNAL ARTICLE
Hiroyuki Kuroda, Takeshi Yoshizako, Nobuhiro Yada, Tomomi Kamimura, Nobuko Yamamoto, Mitsunari Maruyama, Rika Yoshida, Mizuki Fukuda, Yuko Kataoka, Masayuki Itakura, Yasushi Kaji
PURPOSE: Whole-body silicon photomultiplier positron emission tomography (WB SiPM PET) could be used to diagnose breast cancer spread before lumpectomy. We aimed to investigate the method of measuring the tumor size by WB SiPM PET as a basis for diagnosing breast cancer spread in the breast. MATERIALS AND METHODS: We retrospectively reviewed 35 breast cancer lesions in 32 patients who underwent WB SiPM PET/CT in the prone position as preoperative breast cancer examinations from September 2020 to March 2022...
February 12, 2024: Japanese Journal of Radiology
https://read.qxmd.com/read/38339249/breast-cancer-in-the-tissue-of-the-contralateral-breast-reduction
#36
REVIEW
Zoë M A Kuijlaars, Nadine S Hillberg, Loes Kooreman, Carmen A H Severens Rijvers, Shan Shan Qiu
Breast cancer is the most prevalent malignancy among women worldwide, and the increasing number of survivors is due to advances in early diagnosis and treatment efficacy. Consequently, the risk of developing contralateral breast cancer (CBC) among these survivors has become a concern. While surgical intervention with lumpectomy is a widely used primary approach for breast cancer, post-operative breast asymmetry is a potential concern. Many women opt for symmetrizing reduction procedures to improve aesthetic outcomes and quality of life...
January 24, 2024: Cancers
https://read.qxmd.com/read/38332198/comparison-of-long-term-oncological-outcomes-after-central-lumpectomy-versus-nipple-sparing-breast-conserving-surgery-for-centrally-located-breast-cancer-a-propensity-score-matched-study
#37
JOURNAL ARTICLE
Yung-Huyn Hwang, Tae-Kyung Yoo, Sae Byul Lee, Jisun Kim, Il Yong Chung, Beom Seok Ko, Hee Jeong Kim, Jong Won Lee, Byung Ho Son
PURPOSE: To compare the oncological safety of nipple-sparing breast-conserving surgery (BCS) versus central lumpectomy for centrally located breast cancer (CLBC). METHODS: Patients who underwent BCS for CLBC at Asan Medical Center from 2007 to 2018 were reviewed retrospectively. The oncological outcomes of nipple-sparing BCS (NS-BCS) and central lumpectomy were compared using univariate and multivariate Cox regression analyses and compared again after 1:1 propensity score matching (PSM)...
February 8, 2024: Breast Cancer Research and Treatment
https://read.qxmd.com/read/38320360/understanding-treatment-decision-making-in-older-women-with-breast-cancer-a%C3%A2-survey-based-study
#38
JOURNAL ARTICLE
Ruby J Kazemi, Callie VanWinkle, Cecilia M Pesavento, Ton Wang, Lesly A Dossett
INTRODUCTION: For women ≥70 y old with early-stage hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer, the national guidelines recommend the omission of sentinel lymph node biopsy (SLNB) and post-lumpectomy radiotherapy. However, national-level data suggest these treatments remain common. We utilized a survey-based approach to explore patient-level factors driving overutilization. METHODS: We recruited women ≥70 y old with early-stage hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer within 6 mo of surgery...
February 5, 2024: Journal of Surgical Research
https://read.qxmd.com/read/38320169/something-to-dye-for-toward-better-breast-lumpectomy-margins
#39
MULTICENTER STUDY
Lauren C Turza, Craig D Shriver
The development of fluorescence imaging in oncology led to the possibility of using intraoperative devices to improve the precision of surgical techniques.1 In this issue of NEJM Evidence, Smith et al.2 report results from a prospective multicenter trial evaluating the ability of intravenous pegulicianine with an optical head device and software to intraoperatively identify lumpectomy margins with residual cancer and excise them immediately. Identifying these margins intraoperatively avoids the need for a second surgery, which is required when margins are positive on the final pathology...
July 2023: NEJM Evid
https://read.qxmd.com/read/38320161/intraoperative-fluorescence-guidance-for-breast-cancer-lumpectomy-surgery
#40
JOURNAL ARTICLE
Barbara L Smith, Kelly K Hunt, David Carr, Peter W Blumencranz, E Shelley Hwang, Michele A Gadd, Kimberly Stone, Donna L Dyess, Daleela Dodge, Stephanie Valente, Nayana Dekhne, Patricia Clark, Marie Catherine Lee, Laila Samiian, Beth-Anne Lesnikoski, Lynne Clark, Kate Porta Smith, Manna Chang, Daniel K Harris, Brian Schlossberg, Jorge Ferrer, Irene L Wapnir
Fluorescence Guidance for Lumpectomy SurgeryThis prospective trial of 406 patients assessed margin status with and without pegulicianine fluorescence-guided surgery (pFGS) for stages 0 to 3 breast cancers. The use of pFGS met prespecified thresholds for removal of residual tumor and specificity but did not meet the prespecified threshold for sensitivity.
July 2023: NEJM Evid
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