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https://www.readbyqxmd.com/read/28331757/inflammatory-myofibroblastic-tumor-of-the-breast-coexisting-with-pseudoangiomatous-stromal-hyperplasia
#1
Canan Kelten Talu, Yasemin Çakır, Ezgi Hacıhasanoğlu, Cem Leblebici, Şefika Aksoy, Mehmet Ali Nazlı
Inflammatory myofibroblastic tumors (IMTs) are uncommon breast lesions that consist of spindle cells accompanied by plasma cell-rich inflammatory infiltration, which may mimic breast cancer clinico-radiologically. A woman aged 38 years with a breast mass was referred to our general surgery clinic. The physical examination revealed a mass with irregular borders in the upper outer quadrant of the left breast. In mammography, the lesion was 15 mm in diameter with a spheric form and high density. Ultrasonographically, the mass was solid, heterogeneous, and hypoechoic with posterior enhancement...
October 2016: J Breast Health (2013)
https://www.readbyqxmd.com/read/28328633/complications-and-recurrence-in-implant-sparing-oncologic-breast-surgery
#2
Joshua B Elston, Sangeetha Prabhakaran, Amina Lleshi, Brianna Castillo, Weihong Sun, Ambuj Kumar, Zhenjun Ma, Paul D Smith, Deniz Dayicioglu
BACKGROUND: Patients with a history of prior breast augmentation and newly diagnosed breast cancer represent a rapidly expanding and unique subset of patients. Prior studies have described changes in breast parenchyma and characteristic body habitus of previously augmented patients, as well as increased rates of capsular contracture associated with breast conservation therapy. In our current study, we aimed to study the risk factors contributing to morbidity and whether recurrence rates are higher in patients with prior breast augmentation undergoing lumpectomy or mastectomy for breast cancer and identify differences in complications between these 2 groups...
March 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28328631/single-institution-review-of-patients-with-prior-breast-augmentation-undergoing-breast-conservation-therapy-for-breast-cancer
#3
Sangeetha Prabhakaran, Joshua B Elston, Amina Lleshi, Ambuj Kumar, Weihong Sun, Nazanin Khakpour, Deniz Dayicioglu
BACKGROUND: Increasing number of patients with preexisting breast implants desire breast conservation therapy for breast cancer. There is paucity of comparative data on tumor margins and re-excisions in these patients. High re-excision rates up to 25% have been reported in breast conservation therapy patients; efforts to obtain cosmesis and avoid implant rupture might increase this further. We analyzed tumor margins, re-excision rates, and recurrence in previously augmented versus non-augmented patients undergoing lumpectomy for breast cancer...
March 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28299887/fibroepithelial-lesions-in-the-breast-of-adolescent-females-a-clinicopathological-study-of-54-cases
#4
Dara S Ross, Dilip D Giri, Muzaffar M Akram, Jeffrey P Catalano, Cristina Olcese, Kimberly J Van Zee, Edi Brogi
Fibroepithelial lesions (FELs) are the most frequent breast tumors in adolescent females. The pubertal hormonal surge could impact the growth and microscopic appearance of FELs in this age group. In this study, we evaluate the morphology and clinical behavior of FELs in adolescents. We searched the 1992-2012 pathology data base for FELs in females 18 years old or younger (F ≤18 years). Seven FELs from 1975 to 1983 were also included. Three pathologists reviewed all available material. Patient (pt) characteristics and follow-up information were obtained from electronic medical records...
March 2017: Breast Journal
https://www.readbyqxmd.com/read/28295828/are-the-acosog-z0011-trial-findings-being-applied-to-breast-cancer-patients-undergoing-neoadjuvant-chemotherapy
#5
Olga Kantor, Catherine Pesce, Erik Liederbach, Chi-Hsiung Wang, David J Winchester, Katharine Yao
In 2010, the ACOSOG Z0011 trial showed equivalent survival and recurrence between sentinel lymph node biopsy (SLNB) alone versus axillary lymph node dissection (ALND) for those with a tumor positive sentinel node (SN). We examined national trends in axillary surgery following neoadjuvant chemotherapy (NAC) for clinically node positive disease in the years prior to and after the Z0011 trial publication. 12,063 women with cT1-4N1M0 invasive breast cancer who underwent NAC from 2006 to 2013 and had 1-3 positive nodes on pathology were selected from the National Cancer Data Base...
March 13, 2017: Breast Journal
https://www.readbyqxmd.com/read/28291382/cost-implications-of-an-evidence-based-approach-to-radiation-treatment-after-lumpectomy-for-early-stage-breast-cancer
#6
Rachel A Greenup, Rachel C Blitzblau, Kevin L Houck, Julie Ann Sosa, Janet Horton, Jeffrey M Peppercorn, Alphonse G Taghian, Barbara L Smith, E Shelley Hwang
INTRODUCTION: Breast cancer treatment costs are rising, and identification of high-value oncology treatment strategies is increasingly needed. We sought to determine the potential cost savings associated with an evidence-based radiation treatment (RT) approach among women with early-stage breast cancer treated in the United States. PATIENTS AND METHODS: Using the National Cancer Database, we identified women with T1-T2 N0 invasive breast cancers treated with lumpectomy during 2011...
March 14, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28282801/thyroid-cancer-with-concurrent-breast-tubular-cancer-a-case-report-and-literature-review
#7
Ying-Jie Xu, Chen Qian, Jun He, Da-Qing Cheng, Liu-Xia Jiang
Here one concurrent case of a patient with both thyroid and breast cancers was discussed here with a comprehensive literature review. On March 21, 2016, a 42-year-old female patient was admitted into our hospital because of right neck mass and left breast mass for 1 week during a routine health examination. On March 22, the combined procedures of complete resection of right thyroid gland plus isthmus with dissection of lymph nodes in right VI region plus left breast regional lumpectomy were performed under endotracheal anesthesia...
March 3, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28274029/radiotherapy-in-phyllodes-tumour
#8
Sunitha Susan Varghese, Balukrishna Sasidharan, Marie Therese Manipadam, M J Paul, Selvamani Backianathan
INTRODUCTION: Phyllodes Tumour (PT) of the breast is a relatively rare breast neoplasm (<1%) with diverse range of pathology and biological behaviour. AIM: To describe the clinical course of PT and to define the role of Radiotherapy (RT) in PT of the breast. MATERIALS AND METHODS: Retrospective analysis of hospital data of patients with PT presented from 2005 to 2014 was done. Descriptive statistics was used to analyze the results. Simple description of data was done in this study...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28259217/the-first-case-of-her2-invasive-ductal-carcinoma-arising-from-a-breast-hamartoma-and-literature-review
#9
Lea Baer, Sherise Chantell Rogers, Patricia Farrelly, Carmen Tornos, Keith Sweeney
Carcinomas arising from breast hamartomas are exceedingly rare. We present the first reported case of an African-American female presenting with a right breast lump and a subsequent mammogram suggestive of a hamartoma. She later underwent lumpectomy and was found to have HER2+ invasive ductal carcinoma (IDC) arising from a hamartoma. She was amenable to HER2-targeted trastuzumab, hormone therapy and adjuvant radiation but declined chemotherapy. In a review of the literature, IDC is the predominant neoplastic type found in hamartomas...
April 2017: Journal of the National Medical Association
https://www.readbyqxmd.com/read/28245288/polymeric-composite-devices-for-localized-treatment-of-early-stage-breast-cancer
#10
Kwabena Kan-Dapaah, Nima Rahbar, Wole Soboyejo
For early-stage breast cancers mastectomy is an aggressive form of treatment. Therefore, there is a need for new treatment strategies that can enhance the use of lumpectomy by eliminating residual cancer cells with limited side effects to reduce local recurrence. Although, various radiotherapy-based methods have been developed, residual cells are found in 20-55% of the time at the first operation. Furthermore, some current treatment methods result in poor cosmesis. For the last decade, the authors have been exploring the use of polymeric composite materials in single and multi-modal implantable biomedical devices for post-operative treatment of breast cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28244410/preoperative-accelerated-partial-breast-irradiation-for-early-stage-breast-cancer-preliminary-results-of-a-prospective-phase-2-trial
#11
Elizabeth Nichols, Susan B Kesmodel, Emily Bellavance, Cynthia Drogula, Katherine Tkaczuk, Randi J Cohen, Wendla Citron, Michelle Morgan, Paul Staats, Steven Feigenberg, William F Regine
PURPOSE: To assess the feasibility of utilizing 3-dimensional conformal accelerated partial-breast irradiation (APBI) in the preoperative setting followed by standard breast-conserving therapy. PATIENTS AND METHODS: This was a prospective trial testing the feasibility of preoperative APBI followed by lumpectomy for patients with early-stage invasive ductal breast cancer. Eligible patients had T1-T2 (<3 cm), N0 tumors. Patients received 38.5 Gy in 3.85-Gy fractions delivered twice daily...
March 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28214145/effect-of-reduction-mammoplasty-on-acute-radiation-side-effects-and-use-of-lumpectomy-cavity-boosts
#12
Jolinta Y Lin, Rachel Bluebond-Langner, Enid Choi, Sally Cheston, Elizabeth M Nichols, Randi J Cohen, Soren M Bentzen, Cynthia Drogula, Susan Kesmodel, Emily Bellavance, Paula Rosenblatt, Katherine Tkaczuk, Sheri Slezak, Steven J Feigenberg
PURPOSE: Reduction mammoplasty (RM) during breast-conserving surgery is popular among women with large-volume breasts because it reduces redundant breast folds and may decrease skin-related morbidity from radiation therapy. However, RM may obscure the lumpectomy cavity (LC) and pose challenges to administering an LC boost, potentially affecting local control. We investigated the impact of RM on acute side effects and use of LC boosts. METHODS AND MATERIALS: The records of 645 consecutive women treated with whole-breast irradiation at an urban university and 2 community practices between January 2012 and December 2014 were reviewed on an institutional review board-approved study...
January 7, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28210920/choosing-the-appropriate-side-for-subcutaneous-port-catheter-placement-in-patients-with-mastectomy-ipsilateral-or-contralateral
#13
Omer Fatih Nas, Kadir Hacikurt, Ahmet Kaya, Nurullah Dogan, Bekir Sanal, Guven Ozkaya, Halit Ziya Dundar, Cuneyt Erdogan
PURPOSE: To evaluate long-term clinical follow-up results of implanting subcutaneous port catheters (SPCs) on ipsilateral or contralateral with mastectomy side in patients with axillary lymph node dissection. METHODS: A total of 73 patients composed of ipsilateral (34 catheters) and contralateral (39 catheters) groups, with SPCs were included. All patients had lumpectomy or modified radical mastectomy for breast cancer. Ipsilateral and contralateral groups had similar patient characteristics...
February 17, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28210548/does-neoadjuvant-chemotherapy-affect-morbidity-mortality-reoperations-or-readmissions-in-patients-undergoing-lumpectomy-or-mastectomy-for-breast-cancer
#14
Jeffrey Landercasper, Barbara Bennie, Mallory S Bray, Choua A Vang, Jared H Linebarger
BACKGROUND: The influence of neoadjuvant chemotherapy (NAC) prior to breast cancer surgery on postoperative complications is unclear. Our objective was to determine whether NAC was associated with postoperative outcomes in patients undergoing lumpectomy or mastectomy without reconstruction. METHODS: Patients meeting inclusion criteria were identified from the National Surgical Quality Improvement Program (NSQIP) database participant user files from 2005 through 2012, after which NSQIP discontinued the NAC variable...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28168385/postoperative-complications-after-breast-cancer-surgery-are-not-related-to-age
#15
Britt Ten Wolde, Michelle Kuiper, Johannes H W de Wilt, Luc J A Strobbe
INTRODUCTION: Consensus about surgical treatment options for breast cancer in elderly patients remains elusive due to exclusion from clinical trials. Fear of complications due to increased age often is an important factor in the choice of treatment and might result in different treatment of the older patient. METHODS: A total of 1258 female patients who underwent breast cancer surgery for primary diagnosed breast cancer in 2010-2014 were included. Incidence of postoperative complications (POCs) was compared between the younger (18-70 years, N = 1008) and older (≥71 years, N = 250) patients...
February 6, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28162949/sentinel-node-procedure-obsolete-in-lumpectomy-for-ductal-carcinoma-in-situ
#16
Cathelijne Heymans, James van Bastelaar, Ruben G J Visschers, Yvonne L J Vissers
BACKGROUND: Patients with a preoperative needle-biopsy diagnosis of ductal carcinoma in situ (DCIS) may have an indication for a sentinel lymph node biopsy if invasive carcinoma is found. We investigated how often a positive sentinel node and invasive carcinoma occurred in patients with a preoperative diagnosis of DCIS and whether this influenced the adjuvant regime. MATERIALS AND METHODS: From 2005 to 2014, the records of 240 patients with needle-biopsy diagnosis of DCIS were retrospectively reviewed for postoperative pathology outcomes of the sentinel node and breast, and decisions on adjuvant treatment...
October 19, 2016: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28162333/-526-a-brief-psychological-intervention-targeting-persistent-pain-prevention-following-mastectomy-or-lumpectomy-a-pilot-investigation
#17
K Hadlandsmyth, L Dindo, S Sugg, R Wajid, M Zimmerman, B Rakel
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162018/oncoplastic-breast-surgery-does-not-delay-the-onset-of-adjuvant-chemotherapy-a-population-based-study
#18
Anders Klit, Tove Filtenborg Tvedskov, Niels Kroman, Jens Jørgen Elberg, Bent Ejlertsen, Trine Foged Henriksen
BACKGROUND: Only a few studies of limited size have examined whether oncoplastic breast surgery delays the onset of adjuvant chemotherapy as compared to conventional breast surgery. We investigated whether oncoplastic breast surgery causes a delay in the onset of adjuvant chemotherapy in comparison to lumpectomy and mastectomy. MATERIAL AND METHODS: The study is a population-based cohort study. Within the nationwide registry of the Danish Breast Cancer Group (DBCG), we identified 1798 patients who received adjuvant chemotherapy following mastectomy, lumpectomy or oncoplastic breast surgery for early and unilateral invasive breast cancer...
February 6, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28161935/can-we-skip-intraoperative-evaluation-of-sentinel-lymph-nodes-nomogram-predicting-involvement-of-three-or-more-axillary-lymph-nodes-before-breast-cancer-surgery
#19
Soo Kyung Ahn, Min Kyoon Kim, Jongjin Kim, Eunshin Lee, Tae-Kyung Yoo, Han-Byoel Lee, Young Joon Kang, Jisun Kim, Hyeong-Gon Moon, Jung Min Chang, Nariya Cho, Woo Kyung Moon, In Ae Park, Dong-Young Noh, Wonshik Han
Purpose: The American College of Surgeons Oncology Group (ACOSOG) Z0011 trial reported that complete dissection of axillary lymph nodes (ALNs) may not be warranted in women with clinical T1-T2 tumors and one or two involved ALNs who were undergoing lumpectomy plus radiation followed by systemic therapy. The present study was conducted to identify preoperative imaging predictors of ≥3 ALNs. Materials and Methods: The training set consisted of 1917 patients with clinical T1-T2 and node negative invasive breast cancer...
January 25, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28161933/education-level-is-a-strong-prognosticator-in-the-subgroup-aged-more-than-50-years-regardless-of-the-molecular-subtype-of-breast-cancer-study-based-on-the-nationwide-korean-breast-cancer-registry-database
#20
Ki-Tae Hwang, Woochul Noh, Se-Heon Cho, Jonghan Yu, Min Ho Park, Joon Jeong, Hyouk Jin Lee, Jongjin Kim, Sohee Oh, Young A Kim
Purpose: This study investigated the role of education level (EL) as a prognostic factor for breast cancer and to analyze the relationship between EL and various confounding factors. Materials and Methods: Data of 64,129 primary breast cancer patients from the Korean Breast Cancer Registry was analyzed. EL was classified into two groups based on the education period; the high EL group (≥ 12 years) and the low EL group (< 12 years). We performed survival analyses erewith respect to overall survival between the two groups...
February 2, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
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