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Squamoid eccrine ductal carcinoma

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https://www.readbyqxmd.com/read/26796504/squamoid-eccrine-ductal-carcinoma-a-clinicopathologic-study-of-30-cases
#1
Michiel P J van der Horst, Adriana Garcia-Herrera, Dorota Markiewicz, Blanca Martin, Eduardo Calonje, Thomas Brenn
Squamoid eccrine ductal carcinoma is a poorly documented skin adnexal carcinoma showing squamous and duct differentiation. It is regarded to be of low-grade malignant potential, but limited follow-up information is available. To study their clinical behavior and histologic features, 30 squamoid eccrine ductal carcinomas were identified from departmental and referral files. Hematoxylin and eosin-stained sections were reviewed, and immunohistochemistry for carcinoembryonic antigen and epithelial membrane antigen was examined to confirm duct differentiation...
June 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/26171108/squamoid-eccrine-ductal-carcinoma
#2
Kelly Segars, Jared M Gopman, Joshua B Elston, William Carter, Michael A Harrington
No abstract text is available yet for this article.
2015: Eplasty
https://www.readbyqxmd.com/read/26114606/malignant-sweat-gland-tumours-an-update
#3
REVIEW
José C Cardoso, Eduardo Calonje
Cutaneous adnexal tumours can be a diagnostic challenge for the pathologist. This is particularly true in the case of tumours with sweat gland differentiation, due to a large number of rare entities, a multiplicity of names to designate the same neoplasms and consequent lack of consensus regarding their classification and nomenclature. In the traditional view, sweat gland tumours were divided into eccrine and apocrine. However, this has been challenged in recent years, and in fact many of these tumours may have both eccrine and apocrine variants...
November 2015: Histopathology
https://www.readbyqxmd.com/read/25873411/anatomoclinical-study-of-30-cases-of-sclerosing-sweat-duct-carcinomas-microcystic-adnexal-carcinoma-syringomatous-carcinoma-and-squamoid-eccrine-ductal-carcinoma
#4
E Frouin, M D Vignon-Pennamen, B Balme, B Cavelier-Balloy, U Zimmermann, N Ortonne, A Carlotti, L Pinquier, J André, B Cribier
BACKGROUND: Microcystic adnexal carcinoma (MAC), syringomatous carcinoma (SC) and "Squamoid eccrine ductal carcinoma" (SEDC) are rare sclerosing adnexal tumours. OBJECTIVE: To understand the histogenesis of these tumours and possible clinical implications. METHODS: We conducted a retrospective study of 30 cases, 18 MAC, 5 SC and 7 SEDC reviewed and classified by a panel of dermatopathology experts, with immunohistochemical analysis of keratins, including K77, a new keratin specific of eccrine ducts, and PHLDA1 expressed in adnexal structures...
October 2015: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/25752474/squamoid-eccrine-ductal-carcinoma-of-the-scalp
#5
Hsien Chan, Vicki Howard, Denis Moir, Delwyn Dyall-Smith
An 85-year-old man presented with an ulcerated pruritic nodule on the scalp. Histology of a deep curette specimen showed the typical features of a squamoid eccrine ductal carcinoma: superficial squamous differentiation and deep ductal structures.
August 2016: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/25243946/pet-ct-imaging-of-squamoid-eccrine-ductal-carcinoma
#6
Bin Wang, Abel D Jarell, Jonathan L Bingham, Grant H Bonavia
Squamoid eccrine ductal carcinoma is an extremely uncommon type of eccrine carcinoma (EC). An important distinguishing feature of EC is potential for metastasis. Eccrine carcinoma has been reported to metastasize in up to 50% of cases. Despite tumor aggressivity, no recommendations for staging exist. We present the case of a 91-year-old woman with a lesion involving the left index finger confirmed to be squamoid eccrine ductal carcinoma by dermatopathologic evaluation. 18F-FDG PET/CT images revealed widespread multifocal FDG-avid metastatic disease...
April 2015: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/23630640/mohs-micrographic-surgery-in-the-setting-of-squamoid-eccrine-ductal-carcinoma-addressing-a-diagnostic-and-therapeutic-challenge
#7
Shane Clark, Adam Young, Eli Piatigorsky, Larisa Ravitskiy
OBJECTIVE: The purpose of this case report and literature review was to summarize the current knowledge surrounding this rare cutaneous tumor and promote awareness of the success of Mohs micrographic surgery as a definitive therapeutic modality in a case of squamoid eccrine ductal carcinoma. DESIGN: Case report and literature review. SETTING: Squamoid eccrine ductal carcinoma has been introduced as a rare type of eccrine carcinoma with only eight previously reported cases in the literature...
April 2013: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/23110015/squamoid-eccrine-ductal-carcinoma-of-the-scalp
#8
Yong-Han Jung, Hye-Jung Jo, Mi-Seon Kang
Squamoid eccrine ductal carcinoma (SEDC) is an exceedingly rare tumor that shows both squamous and adnexal ductal differentiation. We report a case of this unusual tumor occurring on the occiput of a 53-year-old man. A histopathological examination revealed a nodular lesion infiltrating the dermis and subcutaneous tissue with numerous duct-like structure and squamoid differentiation foci. Five months later, the patient presented with a palpable mass at the site of the previous excision and the right side of the neck...
June 2012: Korean Journal of Pathology
https://www.readbyqxmd.com/read/23021050/dermatology-clinics-what-s-new-in-dermatopathology-news-in-nonmelanocytic-neoplasia
#9
REVIEW
Harleen K Sidhu, Rita V Patel, Gary Goldenberg
This article reviews the recent dermatopathology literature involving nonmelanocytic neoplasia, with a focus on important work done over the last 5 years. The discussion includes advances in the understanding of Merkel cell carcinoma pathogenesis and prognosis; changes in the seventh edition of the American Joint Committee of Cancer staging manual in reference to staging of squamous cell carcinoma and Merkel cell carcinoma; newly described or rare histopathologic patterns and entities including squamoid eccrine ductal carcinoma, rippled-pattern adnexal neoplasms, onychomatricoma, spindle cell predominant trichodiscoma/neurofollicular hamartoma, and myoepithelioma; and microsatellite instability in sebaceous neoplasms of Muir-Torre syndrome and other tumors...
October 2012: Dermatologic Clinics
https://www.readbyqxmd.com/read/22801148/surgical-management-of-recurrent-squamoid-eccrine-ductal-carcinoma-of-the-scalp
#10
REVIEW
Jin Woo Kim, Min Kyeong Jeon, Seok Joo Kang, Hook Sun
Squamoid eccrine ductal carcinoma (SEDC) is an exceedingly rare tumor that shows both squamous differentiation and adnexal ductal differentiation. As our review of the literature revealed, only a total of 7 cases were reported to date. We report an additional case of SEDC occurring on the scalp of a 53-year-old man. Despite complete excision by conventional technique with clear margin, the lesion recurred within a 3-month period, with regional lymph node metastasis. The tumor was completely removed, and the large scalp defect was reconstructed by using scalp rotation flap...
July 2012: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/21642659/syringoid-eccrine-carcinoma-a-clinicopathological-and-immunohistochemical-study-of-four-cases
#11
M Sidiropoulos, S Sade, A Al-Habeeb, D Ghazarian
BACKGROUND: Syringoid eccrine carcinoma (SEC) is a rare malignant adnexal tumour with variable presentations. AIM: To examine the clinicopathological and immunohistochemical features of SEC. METHODS: Four cases were reviewed by three dermatopathologists and the immunohistochemical profile was examined using antibodies against CK5/6, CK7, CK14, CK20, LMWK, HMWK, EMA, mCEA, p63, ER, PR, AR, S-100 and Ber-EP4. RESULTS: The cases occurred in two men and two women, ranging in age from 61 to 87 years (mean 68...
September 2011: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/20010402/squamoid-eccrine-ductal-carcinoma-a-case-report-and-review-of-the-literature
#12
Elina Terushkin, David J Leffell, Tanya Futoryan, Shawn Cowper, Rossitza Lazova
Eccrine ductal carcinoma is a rare adnexal tumor. Squamoid eccrine ductal carcinoma (SEDC) represents an exceptionally rare variant with only 6 cases reported to date. This neoplasm is deeply infiltrative and may provide a diagnostic challenge in superficial shave biopsies of skin. We present a case of SEDC in an immunocompromised patient, who, after an initial shave biopsy for diagnostic purposes, underwent a complete excision of his tumor by Mohs micrographic surgery. A combined histologic and immunohistochemical approach is necessary to identify and confirm the unique characteristics of SEDC...
May 2010: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/19786851/-squamoid-eccrine-ductal-carcinoma-an-unusual-low-grade-case-with-follicular-differentiation-are-these-tumors-squamoid-variants-of-microcystic-adnexal-carcinoma
#13
Sima Kavand, David S Cassarino
Squamoid eccrine ductal carcinoma is a rare primary cutaneous tumor exhibiting both squamous and adnexal ductal differentiation. The cell of origin of these tumors is unknown, and they have been classified both as variants of cutaneous squamous cell carcinoma and as a type of eccrine carcinoma. Only 6 of these tumors have been reported in the literature to date. We report an additional case of a slow-growing tumor, occurring on the great toe of a 61-year-old woman, which was unusual as it showed follicular differentiation in addition to squamoid and ductal areas...
December 2009: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/17518781/ductal-eccrine-carcinoma-with-squamous-differentiation-apropos-a-case
#14
Vishesh Chhibber, Stephen Lyle, Meera Mahalingam
Sweat gland carcinomas are rare. Given this, they can pose a diagnostic challenge especially in shave biopsy specimens. We present a case of ductal eccrine carcinoma with extensive squamoid differentiation that was repeatedly misdiagnosed by multiple dermatopathologists as squamous cell carcinoma in the initial few biopsies. As the distinction between these two neoplasms is crucial to patient management, we highlight the histologic features of this uncommon entity to highlight the potential diagnostic pitfalls...
June 2007: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/16630176/cutaneous-squamous-cell-carcinoma-a-comprehensive-clinicopathologic-classification-part-two
#15
REVIEW
David S Cassarino, Damian P Derienzo, Ronald J Barr
Cutaneous squamous cell carcinoma (SCC) includes many subtypes with widely varying clinical behaviors, ranging from indolent to aggressive tumors with significant metastatic potential. However, the tendency for pathologists and clinicians alike is to refer to all squamoid neoplasms as generic SCC. No definitive, comprehensive clinicopathological system dividing cutaneous SCCs into categories based upon their aggressiveness has yet been promulgated. Therefore, we have proposed the following based upon the malignant potential of SCC variants, separating them into categories of low (< or = 2% metastatic rate), intermediate (3-10%), high (greater than 10%), and indeterminate behavior...
April 2006: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/16466506/cutaneous-squamous-cell-carcinoma-a-comprehensive-clinicopathologic-classification-part-one
#16
REVIEW
David S Cassarino, Damian P Derienzo, Ronald J Barr
Cutaneous squamous cell carcinoma (SCC) includes many subtypes with widely varying clinical behaviors, ranging from indolent to aggressive tumors with significant metastatic potential. However, the tendency for pathologists and clinicians alike is to refer to all squamoid neoplasms as generic SCC. No definitive, comprehensive clinicopathological system dividing cutaneous SCCs into categories based upon their aggressiveness has yet been promulgated. Therefore, we have proposed the following based upon the malignant potential of SCC variants, separating them into categories of low (< or = 2% metastatic rate), intermediate (3-10%), high (greater than 10%), and indeterminate behavior...
March 2006: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/16416622/mohs-micrographic-surgery-for-squamoid-eccrine-ductal-carcinoma
#17
Yong Ju Kim, Ae Ree Kim, Dong Soo Yu
BACKGROUND: Squamoid eccrine ductal carcinoma is a rare cutaneous malignancy. There are no accepted standards for surgical margins in eccrine carcinomas. OBJECTIVE: We report a case of squamoid eccrine ductal carcinoma resembling squamous cell carcinoma and discuss Mohs micrographic surgery as a surgical modality for eccrine carcinomas. METHOD: The patient was a 30-year-old Korean woman with a 4-year history of a nodule on her neck. Following primary diagnosis of squamous cell carcinoma by punch biopsy, the tumor was completely removed by Mohs micrographic surgery with a 2 mm cancer-free margin...
November 2005: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/9088963/squamoid-eccrine-ductal-carcinoma
#18
T Y Wong, S Suster, M C Mihm
We describe three cases of a distinctive cutaneous adnexal neoplasm showing features of eccrine ductal differentiation that were characterized by a prominent squamoid component. The tumours presented as solitary dermal nodules on the head and neck areas and the extremities in elderly patients. Histologically, they were characterized by a prominent squamous proliferation with atypia, keratinous cyst formation and squamous eddies which seemed to merge with areas showing eccrine ductal differentiation, including ductular formations in continuity with eccrine ductal epithelium...
March 1997: Histopathology
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