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Eccrine porocarcinoma

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https://www.readbyqxmd.com/read/29022792/a-case-of-massive-porocarcinoma
#1
T Boam, A Szczap, T Mendes da Costa, N Khirwadkar, L Tho, J Gollogly
A 53-year-old Cambodian woman presented with nodular masses on the right arm suggestive of a sarcoma-type malignancy. The masses were excised and identified as multiple benign eccrine poromas. The patient re-presented after two years with large relapsed tumours and axillary lymph node involvement. A forequarter amputation was undertaken. Histology confirmed the diagnosis of a porocarcinoma, which was likely to be due to malignant transformation of the original poromas. The size and multiplicity of the tumours represents a highly unusual presentation of these rare eccrine neoplasms...
September 15, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28954110/concomitant-poroma-and-porocarcinoma
#2
Álvaro Abarzúa, Sergio Álvarez-Véliz, Catherina Moll-Manzur
Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Both lesions had no clear distinctive features, enhancing the need of high-level clinical suspicion together with surgical excision and histopathology for prompt diagnosis confirmation.
July 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28913302/eccrine-poroma-of-the-postauricular-area
#3
Hyun Rok Lee, Gyu Yong Jung, Hea Kyeong Shin, Dong Lark Lee, Jong Im Lee, Jung Hwan Kim
Eccrine poroma is a common benign cutaneous tumor that originates in an intraepidermal eccrine duct. This tumor exhibits acral distribution (sole, palm), and is rarely encountered in the head and neck area. In fact eccrine poroma in the postauricular area has only been rarely reported. A 55-year-old female visited our hospital with a main complaint of a mass that first developed in the left postauricular area about a year previously. The mass was painless, soft, protruding, domed, and dark red in color, and had slowly enlarged (at presentation it measured 1×1 cm)...
March 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28831427/eosinophilic-variant-of-eccrine-porocarcinoma-of-the-scalp-case-report-and-review-of-the-literature
#4
M D Horwich, J Finch, O Ibrahimi, S S Dadras
Porocarcinoma is a rare malignant neoplasm of the acrosyringium with metastatic potential that most commonly presents on the acral skin in older adults (mean age = 72 years). We present the case of a 43-year-old woman who developed a rapidly growing de novo porocarcinoma on the scalp with an unusual oncocytic appearance. The tumor consisted of benign eccrine poroma that arose from the epidermis and broad pushing borders with minimal cytological atypia but ample eosinophilic cytoplasm with numerous mitotic figures...
September 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28445202/adnexal-carcinomas-treated-with-mohs-micrographic-surgery-a-comprehensive-review
#5
REVIEW
Stanislav N Tolkachjov
BACKGROUND: Adnexal carcinomas (ACs) are rare cutaneous malignancies of sweat gland or pilosebaceous origin. Optimal treatment and metastatic potential of AC are poorly defined. Mohs micrographic surgery (MMS) has been increasingly used to treat AC. OBJECTIVE: To review selected primary cutaneous AC and their treatment outcomes with MMS. MATERIALS AND METHODS: Literature review using PubMed search for articles related to primary cutaneous ACs...
October 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28328706/subungual-eccrine-porocarcinoma-rare-but-possible
#6
Giovanni M Palleschi, Federica Dragoni, Carmelo Urso
No abstract text is available yet for this article.
July 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28133207/-a-case-of-breast-metastasis-of-eccrine-porocarcinoma
#7
Tsuyoshi Mori, Mina Kitamura, Kaori Tomida, Yuki Kawai, Sachiko Sakai, Sachiko Kaida, Toru Miyake, Naomi Kitamura, Hiroya Akabori, Tsuyoshi Yamaguchi, Hiromichi Sonoda, Tomoharu Shimizu, Shigeyuki Naka, Masaji Tani
An 80's woman was diagnosed with eccrine porocarcinoma of the head in 2010.T he tumor was removed surgically but relapsed in the cervical and axillary lymph nodes 2 years later.The patient underwent surgery, and received systemic chemotherapy and radiation.Chest CT after treatment revealed an irregular mass and thickened skin in the left breast.Core needle biopsy specimens were used to diagnose metastasis of eccrine porocarcinoma.A wide excision with a 1 cm margin was performed under local anesthesia.After surgery, supraclavicular lymph node recurrence was detected...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28110827/eccrine-porocarcinoma-patient-characteristics-clinical-and-histopathologic-features-and-treatment-in-7-cases
#8
A Gómez-Zubiaur, S Medina-Montalvo, M D Vélez-Velázquez, I Polo-Rodríguez
Eccrine porocarcinoma is a rare, malignant cutaneous adnexal tumor that arises from the ducts of sweat glands. Found mainly in patients of advanced age, this tumor has diverse clinical presentations. Histology confirms the diagnosis, detects features relevant to prognosis, and guides treatment. Growth is slow, but the prognosis is poor if the tumor metastasizes to lymph nodes or visceral organs. We report 7 cases of eccrine porocarcinoma, describing patient characteristics, the clinical and histopathologic features of the tumors, and treatments used...
May 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28087039/dermoscopic-and-reflectance-confocal-microscopic-presentation-of-relapsing-eccrine-porocarcinoma
#9
Rita Pinheiro, André Oliveira, Pedro Mendes-Bastos
No abstract text is available yet for this article.
February 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28027201/incidence-and-clinical-features-of-rare-cutaneous-malignancies-in-olmsted-county-minnesota-2000-to-2010
#10
Stanislav N Tolkachjov, Adam R Schmitt, John G Muzic, Amy L Weaver, Christian L Baum
BACKGROUND: The incidence of rare cutaneous malignancies is unknown. Current estimates of rare cutaneous malignancy incidences are based on broad epidemiologic data or single institution experiences, not population-based data. OBJECTIVE: To determine the incidence of several rare nonmelanoma skin cancers. MATERIALS AND METHODS: The authors conducted a retrospective chart review of a population-based cohort between the years 2000 and 2010. Residents of Olmsted County, Minnesota, who were diagnosed with a biopsy-proven nonmelanoma skin cancer-excluding basal cell carcinoma and squamous cell carcinoma-were included in this study...
January 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27898349/porocarcinoma-a-systematic-review-of-literature-with-a-single-case-report
#11
Abdulwahid M Salih, F H Kakamad, Rawand A Essa, Goran M Rauf, Masrur S A, Shvan H M, Rawezh Q S, Hunar A H, Dahat A H, Snur Othman
INTRODUCTION: Eccrine porocarcinoma is a very rare type of skin cancer. It is an aggressive dermatological malignancy. We presented a 62-year-old male with long history of a mass in left forearm complicated by distant metastasis and death. A rapid review of literature has been presented. CONCLUSION: Eccrine porocarcinoma is a rare but aggressive type of skin disease. It may arise de novo or complicate a benign skin lesion. Wide local resection is recommended.
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27832810/eccrine-porocarcinoma-of-the-vulva-a-case-report-and-review-of-the-literature
#12
REVIEW
Ayako Fujimine-Sato, Masafumi Toyoshima, Shogo Shigeta, Asami Toki, Takashi Kuno, Izumi Sato, Mika Watanabe, Hitoshi Niikura, Nobuo Yaegashi
BACKGROUND: Malignant tumors arising from the vulva account for only 0.6 % of all cancers in female patients. The predominant histologic type, representing about 90 % of these malignancies, is squamous cell carcinoma. Eccrine porocarcinoma is a rare malignant tumor arising from sweat glands. The incidence of eccrine porocarcinoma is estimated at 0.005-0.01 % of all cutaneous tumors. To the best of our knowledge, only seven previous cases of vulvar eccrine porocarcinoma have been reported in the English-language literature...
November 10, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27721767/metastatic-eccrine-porocarcinoma-a-rare-case-of-successful-treatment
#13
Hiren Mandaliya, Ina Nordman
The successful treatment of the rare malignancy eccrine porocarcinoma (EP) is extremely challenging, often not rewarding and when associated with metastatic disease, therapy results are disappointing. We present a unique case of treatment response of metastatic EP, with a significant disease-free interval. The patient has remained in clinical and radiological remission for 36 months since diagnosis of metastatic disease.
May 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/27593487/eccrine-porocarcinoma-presenting-as-a-hand-cyst
#14
Amer Raheemullah, Shyam Allamaneni, Steven Weber, Ranjodh Singh
Eccrine porocarcinoma is a rare tumor that arises from the epithelium of the eccrine ducts, with a tendency for metastatic spread and a high rate of local recurrence after excision. It was first described in 1963 by Pinkus and Mehregan and can present clinically as a nodule, erosive plaque or a polypoid growth that may ulcerate. The variable clinical appearance of these lesions can make diagnosis challenging and could delay appropriate treatment. If metastasis occurs the prognosis is poor, with a reported mortality rate of up to 80%...
November 2016: Journal of Hand Surgery
https://www.readbyqxmd.com/read/27502253/characteristics-of-eccrine-tumors-in-a-tertiary-institution-a-5-year-retrospective-study
#15
Peiqi Su, Jun Khee Heng, Derrick Chen Wee Aw, Kong Bing Tan
Eccrine tumors are adnexal tumors with a varied clinical presentation and wide histological spectrum. This study aims to consolidate data on the clinical characteristics of eccrine tumors to help improve clinical acumen and management of such tumors. Histopathological records from January 2008 to December 2012 were retrieved. Clinical characteristics of the tumor including site, appearance, symptoms, color, duration prior to presentation, and clinical and histological diagnosis were recorded. Eighty-four patients with eccrine tumors were identified, with seven main types of tumors recognized-hidradenoma (33...
2016: Skinmed
https://www.readbyqxmd.com/read/27307184/cutaneous-collision-tumor-associated-with-porocarcinomatous-and-angiosarcomatous-components-a-potential-diagnostic-pitfall
#16
Rafael Parra-Medina, Mario A Melo-Uribe, Oscar Messa-Botero, Samuel D Morales
Sarcomatoid eccrine porocarcinoma (SEP) is a very rare malignancy including epithelial and mesenchymal components exhibiting pleomorphic cells, nuclear hyperchromasia, and high mitotic activity in both elements. To date, only 6 cases of this uncommon neoplasm have been reported, corresponding to women over 70 years of age with ulcerated skin lesions. The authors describe the first sarcomatoid eccrine porocarcinoma in a 75-year-old male patient with a right hallux lesion, presenting a collision tumor with a mixed population of epithelial cells and a spindle cell angiosarcomatous mesenchymal component each expressing distinct and nonoverlapping morphologic and immunohistochemical features of epithelial and mesenchymal differentiation...
September 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27302529/porocarcinoma-scalp-with-high-risk-features-treated-with-surgery-and-adjuvant-radiotherapy-a-case-report-and-review-of-literature
#17
Wineeta Melgandi, Rony Benson, Abdul Hakin, Suman Bhasker
Eccrine porocarcinoma is a rare malignant sweat gland tumor arising from the intra dermal part of the gland and accounts for only 0.005% of all epithelial cutaneous tumors. Commonly involved site includes extremities and face. Scalp is a rare site for porocarcinoma with less than 20 reported cases so far. Wide local excision with clear margins remains the treatment of choice. Review of literature revealed a local recurrence rate of 37.5% and a nodal involvement risk of 20%. Porocarcinoma of the scalp is peculiar in that the primary tumor may be large at presentation, making surgery with adequate margins difficult...
September 2016: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/27176862/treatment-of-porocarcinoma-with-mohs-micrographic-surgery-the-mayo-clinic-experience
#18
Stanislav N Tolkachjov, Thomas L Hocker, Michael J Camilleri, Christian L Baum
BACKGROUND: Eccrine porocarcinoma (EPC) is a rare malignant adnexal neoplasm with reported metastatic potential and undefined optimal treatment. OBJECTIVE: This study reviews the clinical characteristics and outcomes of patients with EPC treated with Mohs micrographic surgery (MMS). MATERIALS AND METHODS: The authors performed a retrospective chart review of patients with EPC treated by MMS at the Mayo Clinic from 1995 to 2013, recording patient demographics, tumor characteristics, MMS stages to clearance, follow-up, recurrence, metastasis, and mortality...
June 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27159948/immunohistological-expression-of-p16ink4a-is-commonly-present-both-in-benign-and-malignant-sweat-gland-neoplasias
#19
Jun Tsujita, Yumiko Kaku, Toshio Ichiki, Ayaka Eto, Hiromi Maemura, Akiko Otsuka, Risa Nakaie, Noriko Kitagawa, Yuka Morioka, Tomoyo Matsuda, Maiko Yoshida, Masutaka Furue
The expression of p16INK4a has been reported to be a significant marker for malignant transformation of epidermal tumors. However, little is known about sweat gland tumors. We examined the immunohistological expression of p16INK4a in benign and malignant sweat gland tumors. The ductal and acrosyringial portion of normal eccrine glands were positively stained with p16INK4a while it was negative in the normal epidermis. Moderate to strong expression of p16INK4a was found in 16 of 17 eccrine poromas, 4 of 5 hidradenomas, 3 of 3 syringocystadenoma papilliferums, 2 of 2 mixed tumors, and 3 of 3 syringomas...
December 2015: Fukuoka Igaku Zasshi, Hukuoka Acta Medica
https://www.readbyqxmd.com/read/27085107/eccrine-porocarcinoma-presenting-as-an-abdominal-wall-mass-in-a-patient-with-ulcerative-colitis-a-rare-case-report
#20
Narendrasinh Parmar, Mohamed Mohamed, Adel Elmoghrabi, Michael McCann
INTRODUCTION: Eccrine porocarcinoma (EPC) is a rare malignancy of eccrine sweat glands. It is often seen during the sixth to eighth decades of life. We report the first case of eccrine porocarcinoma arising on the abdomen of a 21-year-old patient with ulcerative colitis. CASE PRESENTATION: A 21-Year-old female presented to emergency department with a one month history of an enlarging mass over left lower abdomen. Abdominal examination revealed a slightly erythematous, nodular and non-mobile firm mass in left lower quadrant...
2016: International Journal of Surgery Case Reports
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