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Porokeratosis

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https://www.readbyqxmd.com/read/28398427/disseminated-superficial-actinic-porokeratosis-treated-with-ingenol-mebutate-gel-0-05
#1
Isabella Anderson, Ethan T Routt, Shelbi C Jim On
Disseminated superficial actinic porokeratosis (DSAP) is a chronic condition characterized by numerous atrophic papules and patches with a distinctive peripheral keratotic ridge, typically found on sun-exposed areas. Treatment of DSAP is warranted not only for cosmetic and symptomatic benefits but also to prevent malignant transformation. Successful treatment of DSAP often is difficult and frequently requires the use of multiple modalities. Ingenol mebutate gel 0.05% is a topical medication primarily used for the treatment of actinic keratosis (AK) by inducing cell death...
March 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28300921/porokeratosis-ptychotropica
#2
Ana Carolina Franco Tebet, Tatiana Gandolfi de Oliveira, Anna Rita Ferrante Mitidieri de Oliveira, Fabiolla Sih Moriya, Jayme de Oliveira, Luiz Carlos Cucé
Porokeratosis is a skin disorder clinically characterized by annular plaques with keratotic borders resembling the Great Wall of China and histopathologically by cornoid lamellae. The disease has several clinical variants. Porokeratosis ptychotropica, which has recently become part of these variants, is quite rare and little known. The entity is characterized by verrucous plaques - which may resemble a psoriasis plaque - that affect the regions of the buttocks, most commonly the gluteal cleft, with or without extremity involvement...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300920/porokeratosis-of-mibelli-in-an-hiv-positive-patient
#3
Luiza de Queiroz Ottoni, Priscila Kakizaki, Rafael Ribeiro Pinheiro, José Alexandre de Souza Sittart, Neusa Yuriko Sakai Valente
Porokeratosis represents a group of disorders of epidermal keratinization that are characterized by one or more annular plaques surrounded by a histologically distinctive hyperkeratotic ridge-like border called the cornoid lamella. Many studies showed that organ transplantation and immunosuppression were associated in a significant number of cases. Furthermore, an association with squamous cell carcinoma and basal cell carcinoma has been noted in all variants of porokeratosis. The rarity of this disorder and its atypical clinical presentation - a single lesion on the thumb of an HIV-positive male patient - motivated this report...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300916/porokeratosis-simulating-bowen-s-disease-on-dermoscopy
#4
Alzinira Sousa Herênio, Silvana Maria de Morais Cavalcanti, Emmanuel Rodrigues de França, Clarissa Marques Maranhão, Eliane Ruth Barbosa de Alencar
Porokeratosis is a disorder of epidermal keratinization characterized by the presence of annular hyperkeratotic plaques. Its etiopathogenesis is not yet fully understood, but a relationship with immunosuppression has been reported. Dermoscopic examination revealed a classic yellowish-white ring-like structure that resembled "volcanic crater contour" - the so-called cornoid lamella. We describe a case of porokeratosis in a female patient with chronic lymphedema, which was similar to Bowen's disease due to the many glomerular vessels seen on clinical examination and dermoscopy...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28283894/treatment-of-porokeratosis-a-systematic-review
#5
REVIEW
Till Weidner, Tanja Illing, Diana Miguel, Peter Elsner
BACKGROUND: Porokeratosis (PK) is a rare skin disease of unknown etiology. It consists of a keratinization disorder, which may appear in several clinical forms and can undergo malignant transformation. The histopathological hallmark of PK is the cornoid lamella. While many topical, systemic, and surgical treatment modalities for PK have been described, no randomized controlled trials have been performed yet. Because of a lack of treatment standards for PK, European and international guidelines cannot be created...
March 10, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28266938/follicular-porokeratosis-a-porokeratosis-variant
#6
Ben Tallon, Patrick Emanuel
Porokeratosis derives from a process of abnormal keratinization, resulting in clinical and histologic variants. Follicular involvement is infrequently described, with previous suggestions that it may represent a distinct condition. We describe a case of typical disseminated superficial actinic porokeratosis with additional clinically prominent folliculocentric keratosis. Histologically, this represented follicular cornoid lamellae. These findings support follicular porokeratosis as an anatomic site variant of porokeratosis, as opposed to a distinct condition...
February 27, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28239750/light-and-laser-treatment-modalities-for-disseminated-superficial-actinic-porokeratosis-a-systematic-review
#7
Gregory A Aird, Jenna L Sitenga, Austin Huy Nguyen, Adam Vaudreuil, Christopher J Huerter
Treatment of disseminated superficial actinic porokeratosis (DSAP) is poorly standardized. The present review seeks to comprehensively discuss the potential for laser and light modalities in the treatment of DSAP. A systematic review of light and laser treatment modalities was conducted to include 26 cases of patients with DSAP. Systematic review resulted in 14 articles to be included. Photodynamic therapy (PDT) overall was the least successful treatment modality, with clinical improvement seen in a minority of patients (MAL-PDT: N = 9 patients, 33...
February 27, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28223751/secondary-cutaneous-amyloidosis-in-a-patient-with-mycosis-fungoides
#8
Chan Hee Nam, Min Kee Park, Mi Soo Choi, Seung Phil Hong, Byung Cheol Park, Myung Hwa Kim
Secondary cutaneous amyloidosis refers to clinically unapparent amyloid deposits within the skin in association with a pre-existing skin condition or skin tumors, such as basal cell carcinoma, porokeratosis, solar elastosis, Bowen's disease, and mycosis fungoides. A 70-year-old woman presented with a 6-month history of asymptomatic multiple yellowish plaques on both legs. She had been diagnosed with mycosis fungoides 7 years ago and was treated with psoralen and ultraviolet A radiation (PUVA) therapy, narrow-band ultraviolet B (UVB) therapy, and acitretin for 5 years...
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28217872/craniosynostosis-delayed-closure-of-the-fontanelle-anal-genitourinary-and-skin-abnormalities-cdags-syndrome-first-report-in-a-mexican-patient-and-review-of-the-literature
#9
Rodrigo Pastrana-Ayala, Gretty L Peña-Castro, Adriana M Valencia-Herrera, Carlos A Mena-Cedillos, Sonia Toussaint-Caire, Yumiko I Akaki-Carreño, Constanza García-Delgado, Veronica F Morán-Barroso, Mirna Toledo-Bahena
INTRODUCTION: Craniosynostosis and clavicular hypoplasia, delayed closure of the fontanelle, cranial defects, anal and genitourinary abnormalities, and skin (CDAGS), is an infrequent autosomal recessive entity with only 10 cases reported; no associated gene has been identified so far. CASE REPORT: The proband is a 2-year-old Mexican female with brachycephaly, cleft palate, anal malformation with rectovestibular fistula, and clinodactyly of the third toe overlapping the second...
February 19, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28197991/transformation-of-porokeratosis-ptychotropica-into-invasive-squamous-cell-carcinoma
#10
Daniel R Mazori, Marianna Shvartsbeyn, Shane A Meehan, Sara L Tarsis
No abstract text is available yet for this article.
February 15, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28027122/genitogluteal-porokeratosis-in-a-well-woman
#11
Tracy Kristine Foran, Tania Day, Jennifer Bradford, James Scurry
No abstract text is available yet for this article.
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27904191/a-case-of-psoriasis-encircled-by-porokeratosis
#12
Indrashis Podder, Debabrata Bandyopadhyay
No abstract text is available yet for this article.
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27859984/successful-management-of-disseminated-superficial-actinic-porokeratosis-with-diclofenac-sodium-3-gel
#13
María-Mercedes Otero-Rivas, Romina Rodríguez-Lojo, Iria-Margarita Castiñeiras-Mato, Mercedes Lueiro-Vilariño, Yolanda Juárez-Casado, María-Luisa Fernández-Díaz
No abstract text is available yet for this article.
November 18, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27771123/-circumscribed-palmar-hypokeratosis-cpm-the-diagnostic-value-of-dermoscopy
#14
S Topin-Ruiz, J-M Debarre, E Blanchard, S Kettani, P-J Valmier, L Martin, Y Le Corre
BACKGROUND: Circumscribed palmar hypokeratosis (CPH) is a rare skin disease, first described in 2002, associated with sudden localized reduction of the corneal layer. In most cases, it presents as an isolated rounded erythematous palmar lesion on the thenar eminence. We describe the dermoscopic semiology of CPH in 3 cases. PATIENTS AND METHODS: Three patients between the ages of 59 and 72 presented very limited erythematous lesions suggestive of CPH. Dermoscopic examination of these lesions provided similar findings...
March 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27741114/mycosis-fungoides-patient-accompanied-actinic-keratosis-actinic-keratosis-with-squamous-cell-carcinoma-transformation-and-porokeratosis-after-nbuvb-therapy-1st-case-report-and-review-of-the-literature
#15
REVIEW
Meng-Jie Zhao, Bilal Abdul-Fattah, Xiao-Ying Qu, Cui-Yan Wang, Xia Wang, Yi Ran, Ting Lai, Si-Yuan Chen, Chang-Zheng Huang
INTRODUCTION: Mycosis fungoides (MF) is the most common form of primary cutaneous T cell lymphoma. Narrowband ultraviolet B light (NBUVB) is used increasingly in treating MF because of its good toleration and well-established management. CONCERNS: To discuss the risk factors and underlying pathogenic factors in the patients with secondary skin diseases after NBUVB therapy. METHODS: We report in details the first case of a patient with MF accompanied with actinic keratosis (AK), AK with squamous cell carcinoma (SCC) transformation and porokeratosis after NBUVB therapy...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27613297/dermoscopy-in-general-dermatology-a-practical-overview
#16
REVIEW
Enzo Errichetti, Giuseppe Stinco
Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. dermatoses presenting with erythematous-desquamative patches/plaques (plaque psoriasis, eczematous dermatitis, pityriasis rosea, mycosis fungoides and subacute cutaneous lupus erythematosus), papulosquamous/papulokeratotic dermatoses (lichen planus, pityriasis rosea, papulosquamous sarcoidosis, guttate psoriasis, pityriasis lichenoides chronica, classical pityriasis rubra pilaris, porokeratosis, lymphomatoid papulosis, papulosquamous chronic GVHD, parakeratosis variegata, Grover disease, Darier disease and BRAF-inhibitor-induced acantholytic dyskeratosis), facial inflammatory skin diseases (rosacea, seborrheic dermatitis, discoid lupus erythematosus, sarcoidosis, cutaneous leishmaniasis, lupus vulgaris, granuloma faciale and demodicidosis), acquired keratodermas (chronic hand eczema, palmar psoriasis, keratoderma due to mycosis fungoides, keratoderma resulting from pityriasis rubra pilaris, tinea manuum, palmar lichen planus and aquagenic palmar keratoderma), sclero-atrophic dermatoses (necrobiosis lipoidica, morphea and cutaneous lichen sclerosus), hypopigmented macular diseases (extragenital guttate lichen sclerosus, achromic pityriasis versicolor, guttate vitiligo, idiopathic guttate hypomelanosis, progressive macular hypomelanosis and postinflammatory hypopigmentations), hyperpigmented maculopapular diseases (pityriasis versicolor, lichen planus pigmentosus, Gougerot-Carteaud syndrome, Dowling-Degos disease, erythema ab igne, macular amyloidosis, lichen amyloidosus, friction melanosis, terra firma-forme dermatosis, urticaria pigmentosa and telangiectasia macularis eruptiva perstans), itchy papulonodular dermatoses (hypertrophic lichen planus, prurigo nodularis, nodular scabies and acquired perforating dermatosis), erythrodermas (due to psoriasis, atopic dermatitis, mycosis fungoides, pityriasis rubra pilaris and scabies), noninfectious balanitis (Zoon's plasma cell balanitis, psoriatic balanitis, seborrheic dermatitis and non-specific balanitis) and erythroplasia of Queyrat, inflammatory cicatricial alopecias (scalp discoid lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia and folliculitis decalvans), nonscarring alopecias (alopecia areata, trichotillomania, androgenetic alopecia and telogen effluvium) and scaling disorders of the scalp (tinea capitis, scalp psoriasis, seborrheic dermatitis and pityriasis amiantacea)...
December 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/27579746/porokeratosis-ptychotropica-a-rare-manifestation-with-typical-histological-exam
#17
John Verrinder Veasey, Monique Coelho Dalapicola, Rute Facchini Lellis, Adriana Bittencourt Campaner, Thiago da Silveira Manzione, Maria Clarissa de Faria Soares Rodrigues
Porokeratosis is a disorder of epidermal keratinization characterized clinically by a distinctive ridge-like border, and histologically by cornoid lamellae. The known clinical variants of porokeratosis are: classic porokeratosis of Mibelli, disseminated superficial (actinic) porokeratosis (DSAP), porokeratosis palmaris et plantaris disseminata, linear porokeratosis and punctate porokeratosis. In 1995, a seventh form was described as porokeratosis ptychotropica: a verrucous form resembling psoriasis involving the gluteal cleft presenting on the histological exam multiple cornoid lamellae...
July 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27559506/clinical-and-dermatoscopic-features-of-porokeratosis-palmaris-et-plantaris
#18
Satish Udare, Karishma Hemmady
A dermatoscope is an important tool in a dermatologist's armamentarium as it can eliminate the need for a biopsy in a wide array of conditions. Porokeratosis was described by Mibelli and Respighi in 1893, as a disorder of keratinization which on the basis of distribution patterns was described as five clinical variants that portrayed a coronoid lamella on histopathology. We describe a case of asymptomatic, long-standing palmar and plantar pits, which on dermatoscopy showed features suggestive of porokeratosis, which was later reconfirmed by histopathologic sections...
July 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27502333/two-cases-of-disseminated-superficial-actinic-porokeratosis-treated-with-daylight-mediated-photodynamic-therapy
#19
Tania Salas, Jesus Hernandez-Gil, Alicia Lopez, Maria Dorado, Javier Ruiz, Esther García, Francisco Martinez
No abstract text is available yet for this article.
November 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27468973/disseminated-superficial-actinic-porokeratosis-dsap-significant-improvement-after-local-administration-of-calcipotriol-betamethasone-gel
#20
Georgi Tchernev, Anastasiya Atanasova Chokoeva, Bogdana Ivanova, Hristo Mangarov, Nadezhda Georgieva Vidolova
Porokeratosis is defined as a disorder of keratinization characterized by one or more atrophic patches surrounded by a clinically and histologically distinctive hyperkeratotic ridgelike border called the cornoid lamella. Lesions are most commonly located on the sun-exposed sides of trunk and extremities, while exclusive facial involvement has been also reported. Despite that the exact risk of cutaneous malignancy developing in porokeratosis is unknown, it is confirmed by series of case reports, including squamous cell carcinoma, basal cell carcinoma and even melanoma...
March 2017: Wiener Medizinische Wochenschrift
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