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https://www.readbyqxmd.com/read/28092915/malignant-mixed-m%C3%A3-llerian-tumour-of-the-uterus-analysis-of-44-cases
#1
Silvana Grasso, Vera Loizzi, Valentina Minicucci, Leonardo Resta, Anna Lina Camporeale, Ettore Cicinelli, Gennaro Cormio
OBJECTIVES: The aim of our study was to evaluate the clinicopathological features and prognostic factors of uterine carcinosarcoma. PATIENTS AND METHODS: In this retrospective study, the clinical characteristics of 44 patients with uterine MMMT were evaluated. Survival curves were estimated by the Kaplan-Meier method and compared by the log-rank test. RESULTS: Forty-four patients with uterine carcinosarcoma were referred to our unit between 1995 and 2015...
January 17, 2017: Oncology
https://www.readbyqxmd.com/read/28091710/role-of-concurrent-vaginal-hysterectomy-in-the-outcomes-of-mesh-based-vaginal-pelvic-organ-prolapse-surgery
#2
James C Forde, Bilal Chughtai, Jennifer T Anger, Jialin Mao, Art Sedrakyan
INTRODUCTION AND HYPOTHESIS: Hysterectomy is often performed at the time of pelvic organ prolapse (POP) surgery; yet, there is insufficient evidence regarding the specific effect of hysterectomy on outcomes. We sought to determine the outcomes and associated short-term complications of mesh-based POP surgery with and without concurrent hysterectomy. METHODS: We utilized the New York Statewide Planning and Research Cooperation System (SPARCS) database to identify patients under 55 years of age undergoing surgeries for POP with mesh between 2009 and 2014...
January 13, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28088221/role-of-pelvic-and-para-aortic-lymphadenectomy-in-abandoned-radical-hysterectomy-in-cervical-cancer
#3
Salim Abraham Barquet-Muñoz, Gabriel Jaime Rendón-Pereira, Denise Acuña-González, Monica Vanessa Heymann Peñate, Luis Alonso Herrera-Montalvo, Lenny Nadia Gallardo-Alvarado, David Francisco Cantú-de León, René Pareja
BACKGROUND: Cervical cancer (CC) occupies fourth place in cancer incidence and mortality worldwide in women, with 560,505 new cases and 284,923 deaths per year. Approximately, nine of every ten (87%) take place in developing countries. When a macroscopic nodal involvement is discovered during a radical hysterectomy (RH), there is controversy in the literature between resect macroscopic lymph node compromise or abandonment of the surgery and sending the patient for standard chemo-radiotherapy treatment...
January 14, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28081480/does-the-addition-of-salpingectomy-or-fimbriectomy-to-hysterectomy-in-premenopausal-patients-compromise-ovarian-reserve-a-prospective-study
#4
Y Naaman, Y Hazan, M Gillor, G Marciano, R Bardenstein, Z Shoham, A Ben-Arie
OBJECTIVE: To evaluate changes in ovarian reserve in patients following hysterectomy, with or without bilateral salpingectomy or fimbriectomy. STUDY DESIGN: Open-label, prospective cohort trial of patients undergoing hysterectomy for benign uterine indications. Levels of follicle-stimulating hormone (FSH), anti-Müllerian hormone (AMH), and ultrasonic measures of peak systolic flow velocity/diastolic velocity (S/D) ratio and resistance index (RI) in the ovarian artery were taken from patients before and 6 weeks after hysterectomy, hysterectomy+salpingectomy or hysterectomy+fimbriectomy...
December 27, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28081334/comparison-of-the-distinctive-pathological-features-of-and-p16-and-c-kitexpression-levels-in-benign-and-malignant-endometrial-polyps
#5
Nermin Koç, Selçuk Ayas, Lütfiye Uygur, Nurver Özel Özbay
BACKGROUND/AIM: Histopathological examination is crucial for the effective management of endometrial polyps. Immunohistochemical markers such as p16 and c-Kit may facilitate the differential diagnoses of benign and malignant polyps. The aim of the present study was to explore the expression levels of c-Kit (CD117) and p16 in endometrial polyps of postmenopausal women. MATERIALS AND METHODS: Twenty-five hysterectomy specimens with malignant endometrial polyps and hysterectomy or polypectomy specimens featuring 55 benign polyps were studied...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28079779/pathologically-diagnosed-placenta-accreta-and-hemorrhagic-morbidity-in-a-subsequent-pregnancy
#6
Cassandra Roeca, Sarah E Little, Daniela A Carusi
OBJECTIVE: To identify the relationship between pathologically diagnosed placenta accreta and risk of major morbidity in a subsequent pregnancy. METHODS: We conducted a retrospective cohort study of patients with pathologically diagnosed placenta accreta in an index pregnancy who returned with a subsequent pregnancy at our academic center from 2007 to 2015. Subsequent delivery outcomes included minor, major, or no morbidity. Minor morbidity included estimated blood loss 500-1,500 cc for vaginal and 1,000-1,500 cc for cesarean delivery, transfusion of one to three units of red cells, and minor surgical procedures...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28076262/physician-cost-consciousness-and-use-of-low-value-clinical-services
#7
Michael Grover, Neena Abraham, Yu-Hui Chang, Jon Tilburt
PURPOSE: Choosing Wisely(TM) engaged medical specialties, creating "top 5 lists" of low-value services. We describe primary care physicians' (PCPs') self-reported use of these services and perceived barriers to guideline adherence. We quantify physician cost consciousness and determine associations with use. METHODS: PCP attendees of a continuing medical education conference completed a survey. For each Family Medicine Choosing Wisely behavior, participants reported clinical adherence...
November 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28069180/investigation-of-the-microbiota-of-the-reproductive-tract-in-women-undergoing-a-total-hysterectomy-and-bilateral-salpingo-oopherectomy
#8
Shana M Miles, Britney L Hardy, D Scott Merrell
OBJECTIVE: To conduct a pilot study to investigate the possible presence of bacteria throughout the female reproductive tract and to make a preliminary assessment of whether there are differences in the composition of the microbial communities between these body sites and/or between patients. DESIGN: Prospective pilot study followed by 16S amplification and high-throughput sequencing. SETTING: Tertiary care military hospital. PATIENT(S): A total of 10 women underwent a total hysterectomy with bilateral salpingo-oopherectomy; tissue samples were collected from the vagina, resected cervix, uterus, fallopian tubes, and ovaries...
January 6, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28068945/why-women-bleed-and-how-they-are-saved-a-cross-sectional-study-of-caesarean-section-near-miss-morbidity
#9
S Maswime, E J Buchmann
BACKGROUND: Maternal deaths from 'bleeding during and after caesarean section' (BDACS) have increased in South Africa, and have now become the largest sub-cause of deaths from obstetric haemorrhage. The aim of this study was to describe risk factors and causes of near-miss related to BDACS and interventions used to arrest haemorrhage and treat its effects. METHODS: Cross-sectional prospective study in 13 urban public hospitals in South Africa, from July to December 2014...
January 9, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28068595/the-impact-of-lymphadenectomy-on-survival-endpoints-in-women-with-early-stage-uterine-endometrioid-carcinoma-a-matched-analysis
#10
Ahmed I Ghanem, Nadia T Khan, Meredith Mahan, Ahmed Ibrahim, Thomas Buekers, Mohamed A Elshaikh
OBJECTIVES: The role of pelvic lymphadenectomy (LA) in women with stage I endometrial carcinoma (EC) is controversial. The objective of this study is to investigate the prognostic impact of LA on survival endpoints in matched cohorts of women with stage I EC solely of endometrioid histology. Survival endpoints included recurrence-free (RFS), disease-specific (DSS) and overall survival (OS). METHODS AND MATERIALS: Patients with FIGO stage I EC who underwent hysterectomy with LA as part of their surgical staging between 1/1990 and 6/2015 were matched to a similar group that underwent hysterectomy without lymphadenectomy (NLA), based on stage, grade and adjuvant management...
December 28, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28067743/comparative-perioperative-pain-and-recovery-in-women-undergoing-vaginal-reconstruction-versus-robotic-sacrocolpopexy
#11
Lauren B Westermann, Catrina C Crisp, Donna Mazloomdoost, Steven D Kleeman, Rachel N Pauls
BACKGROUND: In this study of patients undergoing vaginal hysterectomy with either robotic or vaginal prolapse repair, there was no difference in quality of life in the weeks following surgery; however, less narcotics were used, less pain was documented by nurses and Surgical Pain Scale (SPS), and better performance on voiding trials was noted in those undergoing robotic sacrocolpopexy. OBJECTIVES: Minimally invasive surgery for pelvic organ prolapse is the preferred surgical route for optimal recovery...
January 6, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28065954/postpartum-depression-and-associated-factors-after-emergency-peripartum-hysterectomy
#12
Mehmet Baki Senturk, Yusuf Cakmak, Ahmet Ozalp
OBJECTIVE: To investigate post-partum depression after emergency peripartum hysterectomy and associated factors. METHODS: This cross-sectional controlled study was conducted at Batman Gynaecology and Paediatric Diseases Hospital, Batman, Turkey, between June 15 and July 23, 2015, and comprised cases of patients with peripartum hysterectomy and of those who had experienced surgical procedures other than hysterectomy (hypogastric artery ligation and/or B-Lynch suture)...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065812/minimally-invasive-approach-in-type-ii-endometrial-cancer-it-is-wise-and-safe
#13
Giorgia Monterossi, Fabio Ghezzi, Enrico Vizza, Gian Franco Zannoni, Stefano Uccella, Giacomo Corrado, Stefano Restaino, Lorena Quagliozzi, Jvan Casarin, Giorgia Dinoi, Giovanni Scambia, Francesco Fanfani
STUDY OBJECTIVE: The aims of this study were to compare peri-operative and survival outcomes of Type II endometrial cancers patients staged by minimally invasive approaches versus laparotomy. DESIGN: A retrospective cohort study. DESIGN: Classification: Canadian Task Force classification II-2 SETTING: Catholic University of the Sacred Heart of Rome, University of Insubria, Varese and "Regina Elena" National Cancer Institute of Rome. PATIENTS: We enrolled 283 Type II endometrial cancer patients with clinical FIGO stage I-II and pathological stage III with apparent early-stage disease at the pre-operative instrumental examination...
January 5, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28065618/pathological-features-and-clinical-behavior-of-lynch-syndrome-associated-ovarian-cancer
#14
N A J Ryan, D G Evans, K Green, E J Crosbie
OBJECTIVE: Lynch syndrome (LS) is an inherited tumor predisposition condition caused by mutations in the mismatch repair (MMR) genes. Mutation carriers are at increased risk of various malignancies, including ovarian cancer (OC). Relatively little is known about the pathological features and clinical behavior of LS associated OC. METHODS: We analyzed the data of 1047 proven MMR mutated individuals from a prospectively maintained database at a large referral center for genomic medicine in the North West of England...
January 5, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28065219/uterine-artery-embolization-for-management-of-primary-postpartum-hemorrhage-associated-with-placenta-accreta
#15
Wang Zhi-Wei, Li Xiao-Guang, Pan Jie, Zhang Xiao-Bo, Shi Hai-Feng, Yang Ning, Jin Zheng-Yu
Objective To evaluate the efficacy and safety of uterine artery embolization (UAE) in the management of primary postpartum hemorrhage associated with placenta accreta. Methods We retrospectively reviewed the medical records of patients with placenta accreta between January 2010 and August 2014. Totally 18 women (mean age 30.8±4.2 years) of primary massive postpartum hemorrhage with diagnosis of placenta accrete received treatment of UAE after delivery. Images of DSA and medical records were reviewed. Technical success was defined as control of bleeding after embolization...
November 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/28063908/laser-angiography-with-indocyanine-green-icg-to-assess-vaginal-cuff-perfusion-during-total-laparoscopic-hysterectomy-tlh-a-pilot-study
#16
Benjamin D Beran, Marie Shockley, Katrin Arnolds, Pedro Escobar, Stephen Zimberg, Michael L Sprague
STUDY OBJECTIVE: To determine feasibility of using laser angiography with ICG to assess vaginal cuff vascular perfusion during TLH. DESIGN: Pilot feasibility trial DESIGN CLASSIFICATION: Canadian Task Force Class II-2 SETTING: Academic-affiliated hospital PATIENTS: Twenty women undergoing TLH for benign disease. INTERVENTIONS: Participants underwent 1:1 randomization of energy method used for colpotomy (ultrasonic versus monopolar) and vaginal cuff closure suture (barbed versus non-barbed)...
January 4, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28062902/transvaginal-excision-of-complete-vaginal-septum-with-hysterectomy-in-a-nulliparous-woman-with-uterus-didelphys
#17
Peter L Dwyer, Debjyoti Karmakar
No abstract text is available yet for this article.
January 6, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28060142/the-importance-of-appendectomy-in-surgery-for-mucinous-adenocarcinoma-of-the-ovary
#18
Mikkel Rosendahl, Laura Amalie Haueberg Oester, Claus Kim Høgdall
OBJECTIVE: The aim of this study was to assess the importance of appendectomy during surgery for mucinous ovarian cancer. It can be difficult to distinguish between primary ovarian and primary appendiceal cancers clinically, histologically, and immunohistochemically. Removal of the appendix may facilitate differential diagnosis, improve staging, and possibly increase 5-year survival but may also be associated with increased postsurgical morbidity. In the largest population published to date, we analyze and discuss these matters...
January 4, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28060139/is-older-age-a-real-adverse-prognostic-factor-in-women-with-early-stage-endometrial-carcinoma-a-matched-analysis
#19
Laura Haley, Charlotte Burmeister, Thomas Buekers, Mohamed A Elshaikh
OBJECTIVES: The aim of this study was to evaluate if older age alone negatively impacts survival endpoints in women with early-stage uterine endometrioid carcinoma (EC), or its reported prognostic impact is due to an interaction with other well-known adverse factors using matched-analysis methodology. METHODS: We identified 1254 patients with International Federation of Gynecology and Obstetrics stage I-II EC who underwent hysterectomy at our institution. We created 2 matched groups based on International Federation of Gynecology and Obstetrics stage, tumor grade, lymph node dissection status, and the type of adjuvant management...
January 4, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28058000/vesicovaginal-fistula-presenting-as-a-large-abdominal-pseudocyst-a-rare-case
#20
Gaurav Vinod Kasat, Prakash W Pawar, Ajit S Sawant, Ashwin S Tamhankar
We present a rare case of indirect vesicovaginal fistula (VVF) in a patient with small capacity bladder. The fistula was between abdominal pseudocyst (APC) arising from bladder and vagina - and hence, an indirect VVF. A 35-year-old female had a history of emergency obstetric hysterectomy with iatrogenic bladder injury. Postoperatively, the patient developed VVF and large APC. Patient's micturating cystourethrogram was suggestive of small capacity bladder with bilateral Grade IV vesicoureteral reflux with a well-defined APC arising from superior surface of bladder to L4-L5 lumbar vertebrae...
October 2016: Urology Annals
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