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https://www.readbyqxmd.com/read/29142801/idiopathic-acquired-dacryocystocele-presenting-only-with-epiphora-a-very-rare-case-report
#1
Muhammad Jahanzaib Anwar, Saad A Choudhry, Muhammad Aadil, Ahmer Asif, Atif Ameer
A 42-years-old male presented with left medial canthal swelling, accompanied with only mild epiphora. There was no history of dacryocystitis, mid-facial trauma, surgery, or bloody tears. On examination, there was an immobile, subcutaneous, non-inflammatory mass below the medial canthal tendon. Lacrimal irrigation showed blockade at the nasolacrimal duct. A computerized axial tomography (CAT) scan revealed a non-enhancing, low-density, cystic lesion at the inferomedial margin of the orbit. There were no signs of bony erosion, consistent with idiopathic acquired dacryocystocele...
September 4, 2017: Curēus
https://www.readbyqxmd.com/read/29131698/the-anti-inflammatory-and-antioxidant-effects-of-salvia-officinalis-on-lipopolysaccharide-induced-inflammation-in-rats
#2
Umut Kerem Kolac, Mehmet Cengiz Ustuner, Neslihan Tekin, Derya Ustuner, Emine Colak, Emre Entok
Salvia officinalis, which has a high phenolic acid and flavonoid content, is a powerful antioxidant and anti-inflammatory herb. Inflammation plays an important role in the pathophysiology of many diseases and could cause damage by means of oxidative stress. The aim of this study was to investigate the anti-inflammatory and antioxidant activity of S. officinalis formed lipopolysaccharide (LPS)-induced experimental inflammation model. Four- to five-month-old 42 female Wistar albino rats were divided into six groups...
November 13, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29131633/effect-of-the-helix-coil-transition-in-bovine-skin-gelatin-on-its-associative-phase-separation-with-lysozyme
#3
Yurij A Antonov, Irina Zhuravleva, Alexander Volodine, Paula Moldenaers, Ruth Cardinaels
It is known that the formation of electrostatic polyelectrolyte complexes can induce conformational changes in the interacting macromolecules. However, the opposite effect, namely, that of the helix-coil transition of one of the interacting polyelectrolytes on its associative phase separation with another polyelectrolyte and the possible phase transitions in such systems, has not been determined. Atomic force and confocal laser scanning microscopy, phase analysis, dynamic and electrophoretic light scattering, turbidimetry, absorption, and fluorescence measurements as well as differential scanning calorimetry and rheology were used to study the effect of the helix-coil transition in bovine skin gelatin (Gel) on its associative phase separation with hen egg white lysozyme (Lys) at different temperatures (18-40 °C) and various Lys/Gel weight ratios (0...
November 13, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29123915/global-cerebral-ischemia-with-subsequent-respiratory-arrest-in-a-cat-after-repeated-use-of-a-spring-loaded-mouth-gag
#4
Emily A Hartman, Robert J McCarthy, Mary A Labato
Case summary: A 10-year-old neutered male domestic shorthair cat was evaluated because of signs of stertorous breathing and reverse sneezing of 8 months' duration. A CT scan performed 1 week before evaluation indicated nasopharyngeal stenosis or collapse. Increased respiratory effort, stertorous breathing, coughing, reverse sneezing, bilateral black ocular discharge and mucoid left nasal discharge were noted. Rhinoscopy suggested possible nasopharyngeal stenosis. Balloon dilation was attempted but unsuccessful...
July 2017: JFMS open reports
https://www.readbyqxmd.com/read/29115902/open-mouth-jaw-locking-in-cats-a-literature-review-and-use-of-computed-tomography-in-three-cases
#5
Anna E Nutt, Thomas Anderson, Margherita Gracis, Ivan Doran, Chris Warren-Smith, Sorrel J Langley-Hobbs
Case series summary This report summarises and reviews the published cases of open-mouth jaw locking in cats and describes three further cases. Case 1 was a 5-year-old, 5.3 kg male neutered domestic shorthair cat. CT identified changes consistent with temporomandibular joint (TMJ) dysplasia with osseous degenerative changes, and the cat subsequently underwent bilateral partial zygomectomy with bilateral partial coronoidectomy. Case 2 was a 10-year-old, 6.0 kg male neutered Exotic Shorthair. Aside from a fracture of the left maxillary canine tooth crown and absence of the left maxillary fourth premolar tooth, no abnormalities were found on CT scan...
November 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29110603/characterization-of-polyethersulfone-membranes-for-tear-fluid-collection
#6
Q Yang, X Liu, Z Song, L Lin, K Wu
This study evaluated the utility of polyethersulfone membranes (PESms) for tear collection and compared it with two frequently employed approaches: the use of Schirmer test paper (STP) and capillary tube (CaT). STP and PESms of 0.45 and 0.65 μm (PESm65) were examined using scanning electron microscopy (SEM), applied to soak up water and cellular lysates, and employed to collect tear fluid (TF) from rabbits. The proteins in the cellular lysates and TF were characterized through band profiling of SDS-polyacrylamide electrophoresis (PAGE) gels and Western blot analyzing...
November 1, 2017: Current Molecular Medicine
https://www.readbyqxmd.com/read/29098568/the-signaling-of-protease-activated-receptor-2-activating-peptide-induced-contraction-in-cat-esophageal-smooth-muscle-cells
#7
Hyun Su Ha, Se Eun Lee, Hyun Seok Lee, Gil Hyung Kim, Chan Jong Yoon, Jong Soo Han, Ji-Yun Lee, Uy Dong Sohn
Protease-activated receptors (PARs) are a family of G protein-coupled receptors with a unique activation mechanism involving proteolytic cleavage of the extracellular N-terminal domain of the receptor. PAR2 has a contractile effect on esophageal smooth muscle. We investigate the signaling pathways of the PAR2-activating peptide (PAR2-AP) induced contraction in cat esophageal smooth muscle cells. The length of freshly isolated smooth muscle cells and permeabilized cells from feline esophagus were measured by scanning micrometry, and by confirming molecular basis via western blot analysis...
November 2, 2017: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/29098440/taxonomic-identification-of-the-thermotolerant-and-fast-growing-fungus-lichtheimia-ramosa-h71d-and-biochemical-characterization-of-the-thermophilic-xylanase-lrxyna
#8
María Teresa Alvarez-Zúñiga, Alejandro Santiago-Hernández, Johan Rodríguez-Mendoza, Jorge E Campos, Patricia Pavón-Orozco, Sergio Trejo-Estrada, María Eugenia Hidalgo-Lara
The zygomycete fungus Lichtheimia ramosa H71D, isolated from sugarcane bagasse compost, was identified by applying phylogenetic analysis based on the DNA sequence of the Internal Transcribed Spacer (ITS), and subsequent secondary structure analysis of ITS2. L. ramosa H71D was able to grow over a wide range of temperatures (25-45 °C), manifesting optimal growth at 37 °C. A 64 kDa xylanase (named LrXynA) was purified from the culture supernatant of L. ramosa H71D grown on 2% carboxymethylcellulose (CMC), as the only carbon source...
November 2, 2017: AMB Express
https://www.readbyqxmd.com/read/29080485/suppression-of-the-release-of-arsenic-from-arsenopyrite-by-carrier-microencapsulation-using-ti-catechol-complex
#9
Ilhwan Park, Carlito Baltazar Tabelin, Kagehiro Magaribuchi, Kensuke Seno, Mayumi Ito, Naoki Hiroyoshi
Arsenopyrite is the most common arsenic-bearing sulfide mineral in nature, and its weathering contributes to acid mine drainage (AMD) formation and the release of toxic arsenic (As). To mitigate this problem, carrier-microencapsulation (CME) using titanium (Ti)-catechol complex (i.e., Ti-based CME) was investigated to passivate arsenopyrite by forming a protective coating. Ti(4+) ion dissolved in sulfuric acid and catechol were used to successfully synthesize Ti(IV) tris-catecholate complex, [Ti(Cat)3](2-), which was stable in the pH range of 5-12...
October 14, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29070448/exposure-to-the-herbicide-2-4-d-produces-different-toxic-effects-in-two-different-phytoplankters-a-green-microalga-ankistrodesmus-falcatus-and-a-toxigenic-cyanobacterium-microcystis-aeruginosa
#10
Erika Berenice Martínez-Ruiz, Fernando Martínez-Jerónimo
The extensive use of 2,4-dichlorophenoxiacetic acid (2,4-D) in agriculture is an important source of pollution to water and soil. Toxicity of commonly used herbicides to non-target, planktonic photosynthetic organisms has not been described completely yet. Therefore, we determined the effect of subinhibitory 2,4-D concentrations on the Chlorophycean alga Ankistrodesmus falcatus and on a toxigenic strain of the cyanobacterium Microcystis aeruginosa. Population growth, photosynthetic pigments, macromolecular biomarkers (carbohydrates, lipids, and protein), and antioxidant enzymes (catalase [CAT], glutathione peroxidase [GPx], and superoxide dismutase [SOD]) were quantified, and the integrated biomarker response (IBR) was calculated...
October 22, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29067484/crystal-structure-and-iterative-saturation-mutagenesis-of-chkred20-for-expanded-catalytic-scope
#11
Feng-Jiao Zhao, Yun Jin, Zhongchuan Liu, Chao Guo, Tong-Biao Li, Zi-Yi Li, Ganggang Wang, Zhong-Liu Wu
ChKRED20 is an efficient and robust anti-Prelog ketoreductase that can catalyze the reduction of ketones to chiral alcohols as pharmaceutical intermediates with great industrial potential. To overcome its limitation on the bioreduction of ortho-substituted acetophenone derivatives, the X-ray crystal structure of the apo-enzyme of ChKRED20 was determined at a resolution of 1.85 Å and applied to the molecular modeling and reshaping of the catalytic cavity via three rounds of iterative saturation mutagenesis together with alanine scanning and recombination...
December 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29027670/chiari-like-malformation-in-two-cats
#12
S Minato, M Baroni
Two male, neutered, domestic, shorthaired cats were evaluated for progressive paresis and ataxia. Neurological examinations suggested a spinal cord lesion in each case. Complete blood examination and cerebrospinal fluid analysis were unremarkable in both cats. MRI revealed malformation of the occipital bone with herniation of the cerebellar vermis through the foramen magnum but without syringomyelia. Chiari-like malformation was suspected in both patients. MRI repeated one year later in both cats because of progression of clinical signs yielded the same findings as the initial scans...
October 13, 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/28994206/the-computed-tomographic-tree-in-bud-pattern-characterization-and-comparison-with-radiographic-and-clinical-findings-in-36-cats
#13
Harriet Hahn, Swan Specchi, Isabelle Masseau, Carol Reinero, Ghita Benchekroun, Jaime Rechy, Gabriela Seiler, Pascaline Pey
In humans, a CT "tree-in-bud" pattern has been described as a characteristic of centrilobular bronchiolar dilation, with bronchiolar plugging by mucus, pus, or fluid. Aims of this retrospective, descriptive, multi-center study were to characterize the CT appearance of a "tree-in-bud" pattern in a group of cats, and compare this pattern with radiographic and clinical findings. Databases from four hospitals were searched during the period of January 2012 to September 2015 and cats with thoracic radiographs, thoracic CT scans and CT reports describing findings consistent with a "tree-in-bud" pattern were included...
October 9, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28986596/palisade-endings-of-extraocular-muscles-develop-postnatally-following-different-time-courses
#14
COMPARATIVE STUDY
Roland Blumer, Johannes Streicher, María A Davis-López de Carrizosa, Rosa R de la Cruz, Angel M Pastor
Purpose: To analyze in a frontal-eyed mammal (cat) the postnatal development of palisade endings in extraocular muscles (EOMs) and to compare the spatiotemporal and quantitative patterns of palisade endings among individual rectus muscles. Methods: Cats of different ages ranging from birth to adult stage were studied. EOM whole-mount preparations were fluorescently labeled using six combinations of triple staining and analyzed in the confocal laser scanning microscope...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28983492/comparison-of-the-ctdi-and-aapm-report-no-111-methodology-in-adult-adolescent-and-child-head-phantoms-for-msct-and-dental-cbct-scanners
#15
Celina L Li, Yogesh Thakur, Nancy L Ford
This study investigates the dosimetry methodology proposed by the American Association of Physicists in Medicine (AAPM) task group 111 and compares with the computed tomography dose index (CTDI) method and the SEDENTEXCT DI method on one clinical multislice CT and two dental cone beam CT (CBCT) scanners using adult, adolescent, and child head phantoms. Following the AAPM method, the normalized (100 mAs) equilibrium doses ([Formula: see text]) for Toshiba Aquilion One MSCT computed using dose measurements from the central hole of the phantom ([Formula: see text]), the peripheral hole of the phantom, ([Formula: see text]), and by the [Formula: see text] equation ([Formula: see text]) are in the range from 20 to 25 mGy...
July 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28947014/characteristics-of-patients-with-increasing-copd-assessment-test-scores-within-3-years
#16
Hidehiro Irie, Shotaro Chubachi, Minako Sato, Akihiro Tsutsumi, Ichiro Nakachi, Naoki Miyao, Kazumi Nishio, Hidetoshi Nakamura, Koichiro Asano, Tomoko Betsuyaku
BACKGROUND: The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a subjective measure of quality of life. The aim of this study was to examine the characteristics of COPD patients with increasing CAT scores within 3 years. METHODS: Keio University and its affiliate hospitals conducted an observational COPD cohort study over 3 years. St. George's Respiratory Questionnaire (SGRQ) and CAT were completed at baseline and annually thereafter. Patients who had at least 3 CAT scores were included (n = 315)...
October 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28945810/spontaneous-local-diastolic-subsarcolemmal-calcium-releases-in-single-isolated-guinea-pig-sinoatrial-nodal-cells
#17
Syevda G Sirenko, Dongmei Yang, Larissa A Maltseva, Mary S Kim, Edward G Lakatta, Victor A Maltsev
Uptake and release calcium from the sarcoplasmic reticulum (SR) (dubbed "calcium clock"), in the form of spontaneous, rhythmic, local diastolic calcium releases (LCRs), together with voltage-sensitive ion channels (membrane clock) form a coupled system that regulates the action potential (AP) firing rate. LCRs activate Sodium/Calcium exchanger (NCX) that accelerates diastolic depolarization and thus participating in regulation of the time at which the next AP will occur. Previous studies in rabbit SA node cells (SANC) demonstrated that the basal AP cycle length (APCL) is tightly coupled to the basal LCR period (time from the prior AP-induced Ca2+ transient to the diastolic LCR occurrence), and that this coupling is further modulated by autonomic receptor stimulation...
2017: PloS One
https://www.readbyqxmd.com/read/28945310/brain-structural-correlates-of-irritability-findings-in-a-large-healthy-cohort
#18
Bianca Besteher, Letizia Squarcina, Robert Spalthoff, Marcella Bellani, Christian Gaser, Paolo Brambilla, Igor Nenadić
Irritability and nonviolent aggression are common behavioral features across the population, yet there is limited neurobiological research into subclinical phenotypes representing the lower edge of a symptom continuum ranging from slight irritability to criminal violence. We studied brain structural correlates of irritability in a large healthy cohort to test the hypothesis of associations with fronto-limbic brain structures implicated in mood regulation. In a large multicenter effort, we recruited 409 mentally healthy adults from the community, who received T1-weighted high-resolution 3 T MRI scans...
September 25, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28925790/morphological-variation-of-the-caudal-fossa-of-domestic-cat-skulls-assessed-with-computed-tomography-and-geometric-morphometrics-analysis
#19
Caroline R Gordon, Thomas W Marchant, Joanna Lodzinska, Jeffery J Schoenebeck, Tobias Schwarz
Objectives This study aimed to investigate differences and demonstrate a normal range of morphological variation of the caudal fossa of the cranium of domestic cats. Methods CT scans of 32 domestic cat heads of 11 breeds were included. Isosurfaces from skulls were characterised through three-dimensional geometric morphometrics using geographical landmarks placed on the internal surface of the caudal fossa and foramen magnum. Raw data was transformed with a Procrustes fit and coordinate covariance was analysed by principal components to establish breed- and sex-level differences...
September 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28898344/-lung-epithelioid-hemangioendothelioma-report-of-one-case
#20
Manuel Quiroz, Álvaro Undurraga, Rafael Moya, Cristina Fernández, Katiuska Bezares, Virginia Linacre
Epithelioid hemangioendothelioma is a multifocal tumor that rarely metastasizes. It is difficult to diagnose, most often it is an incidental finding in young asymptomatic women. The radiologic pattern is heterogeneous. Histologic confirmation of Weibel-Palade bodies or immunohistochemistry based on specific tumor markers such as factor VIII and CD34 are the most important finding to confirm the diagnosis. We report a 21 years old woman Presenting with cough and dyspnea. A chest X ray was suggestive of tuberculosis...
May 2017: Revista Médica de Chile
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