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REVIEW
Lourdes M DelRosso, Daniel L Picchietti, Denise Sharon, Karen Spruyt, Judith A Owens, Arthur S Walters, Marco Zucconi, Raffaele Ferri
This systematic review evaluates the scientific literature on pediatric periodic limb movement disorder (PLMD), adhering to PRISMA guidelines and utilizing PICOS criteria. The search across PubMed, EMBASE, and Scopus yielded 331 articles, with 17 meeting inclusion criteria. Diagnostic criteria evolved, with polysomnography and PLMS index ≥5 required since 2003. Also, PLMD diagnosis mandates clinical consequences like insomnia, hypersomnia, and fatigue, excluding comorbidities causing sleep disruption...
April 16, 2024: Sleep Medicine Reviews
#2
JOURNAL ARTICLE
Monica Aggarwal, Brian G Hutchison, Kristina M Kokorelias, Vivian R Ramsden, Noah M Ivers, Andrew Pinto, Ross E G Uphsur, Sabrina T Wong, Nick Pimlott, Steve Slade
BACKGROUND: The generation of research evidence and knowledge in primary health care (PHC) is crucial for informing the development and implementation of interventions and innovations and driving health policy, health service improvements, and potential societal changes. PHC research has broad effects on patients, practices, services, population health, community, and policy formulation. The in-depth exploration of the definition and measures of research impact within PHC is essential for broadening our understanding of research impact in the discipline and how it compares to other health services research...
April 23, 2024: JMIR Research Protocols
#3
JOURNAL ARTICLE
Shujie Zhang, Laibo Song, Ruina Zheng, Fang Zhang, Qimeng Wang, Xiaosui Mao, Jin-Xuan Fan, Bo Liu, Yuan-Di Zhao, Wei Chen
Accurate analysis of microRNAs (miRNAs) at the single-cell level is extremely important for deeply understanding their multiple and intricate biological functions. Despite some advancements in analyzing single-cell miRNAs, challenges such as intracellular interferences and insufficient detection limits still remain. In this work, an ultrasensitive nanopore sensor for quantitative single-cell miRNA-155 detection is constructed based on ionic current rectification (ICR) coupled with enzyme-free catalytic hairpin assembly (CHA)...
April 23, 2024: Analytical Chemistry
#4
JOURNAL ARTICLE
Lee Jussim
Because the term "diversity" has two related but different meanings, what authors mean when they use the term is inherently unclear. In its broad form, it refers to vast variety. In its narrow form, it refers to human demographic categories deemed deserving of special attention by social justice-oriented activists. In this article, I review Hommel's critique of Roberts et al. (2020), which, I suggest, essentially constitutes two claims: that Roberts et al.'s (2020) call for diversity in psychological science focuses exclusively on the latter narrow form of diversity and ignores the scientific importance of diversity in the broader sense, and ignoring diversity in the broader sense is scientifically unjustified...
May 2024: Perspectives on Psychological Science
#5
JOURNAL ARTICLE
Bernhard Hommel
The increasing use of political activist arguments and reasoning in scientific communication about diversity is criticized. Based on an article of Roberts et al. (2020) on "racial inequality in psychological research," three hallmarks of the intrusion of activist thinking into science are described: blindness to the multidimensional nature of diversity, the failure to distinguish psychological mechanisms from the impact of moderators, and a blindness to agency as an explanation for psychological observations...
May 2024: Perspectives on Psychological Science
#6
JOURNAL ARTICLE
Steven Othello Roberts
In the spirit of America's Shakespeare, August Wilson (1997), I have written this article as a testimony to the conditions under which I, and too many others, engage in scholarly discourse. I hope to make clear from the beginning that although the ideas presented here are not entirely my own-as they have been inherited from the minority of scholars who dared and managed to bring the most necessary, unpalatable, and unsettling truths about our discipline to the broader scientific community-I do not write for anyone but myself and those scholars who have felt similarly marginalized, oppressed, and silenced...
May 2024: Perspectives on Psychological Science
#7
JOURNAL ARTICLE
Sushant Sharma Chaudhary, Andrew Toivonen, Gaurav Waratkar, Geoffrey Mo, Deep Chatterjee, Sarah Antier, Patrick Brockill, Michael W Coughlin, Reed Essick, Shaon Ghosh, Soichiro Morisaki, Pratyusava Baral, Amanda Baylor, Naresh Adhikari, Patrick Brady, Gareth Cabourn Davies, Tito Dal Canton, Marco Cavaglia, Jolien Creighton, Sunil Choudhary, Yu-Kuang Chu, Patrick Clearwater, Luke Davis, Thomas Dent, Marco Drago, Becca Ewing, Patrick Godwin, Weichangfeng Guo, Chad Hanna, Rachael Huxford, Ian Harry, Erik Katsavounidis, Manoj Kovalam, Alvin K Y Li, Ryan Magee, Ethan Marx, Duncan Meacher, Cody Messick, Xan Morice-Atkinson, Alexander Pace, Roberto De Pietri, Brandon Piotrzkowski, Soumen Roy, Surabhi Sachdev, Leo P Singer, Divya Singh, Marek Szczepanczyk, Daniel Tang, Max Trevor, Leo Tsukada, Verónica Villa-Ortega, Linqing Wen, Daniel Wysocki
Multimessenger searches for binary neutron star (BNS) and neutron star-black hole (NSBH) mergers are currently one of the most exciting areas of astronomy. The search for joint electromagnetic and neutrino counterparts to gravitational wave (GW)s has resumed with ALIGO's, AdVirgo's and KAGRA's fourth observing run (O4). To support this effort, public semiautomated data products are sent in near real-time and include localization and source properties to guide complementary observations. In preparation for O4, we have conducted a study using a simulated population of compact binaries and a mock data challenge (MDC) in the form of a real-time replay to optimize and profile the software infrastructure and scientific deliverables...
April 30, 2024: Proceedings of the National Academy of Sciences of the United States of America
#8
JOURNAL ARTICLE
Emma Grace Carey, Faith Oluwasemilore Adeyemi, Lakshmi Neelakantan, Blossom Fernandes, Mina Fazel, Tamsin Ford, Anne-Marie Burn
BACKGROUND: Improving access to mental health data to accelerate research and improve mental health outcomes is a potentially achievable goal given the substantial data that can now be collected from mobile devices. Smartphones can provide a useful mechanism for collecting mental health data from young people, especially as their use is relatively ubiquitous in high-resource settings such as the United Kingdom and they have a high capacity to collect active and passive data. This raises the interesting opportunity to establish a large bank of mental health data from young people that could be accessed by researchers worldwide, but it is important to clarify how to ensure that this is done in an appropriate manner aligned with the values of young people...
April 23, 2024: JMIR Formative Research
#9
REVIEW
Li Zeng, Jialin Wang, Guiling Liu, Zhongqing Yuan, Fengxue Yang, Dong Liu, Lan Li, Yihang Peng
BACKGROUND: The urgency and risk of clinical nursing may cause nurses to experience traumatic stress, but it may also lead to posttraumatic growth. However, no study has comprehensively analyzed the prevalence of posttraumatic growth among nurses using a unified outcome measure and a validated assessment tool. AIM: This study aims to systematically assess the prevalence and factors of posttraumatic growth among nurses based on the Posttraumatic Growth Inventory (PTGI)...
April 23, 2024: International Nursing Review
#10
REVIEW
Navigating the Tumor Microenvironment: Mesenchymal Stem Cell-Mediated Delivery of Anticancer Agents.
Muhammad Ahsan Waqar, Muhammad Zaman, Muhammad ShafeeqUrRahman, Rabeel Khan, Imtiaz Majeed
Scientific knowledge of cancer has advanced greatly throughout the years, with most recent studies findings includes many hallmarks that capture disease's multifaceted character. One of the novel approach utilized for the delivery of anti-cancer agents includes mesenchymal stem cell mediated drug delivery. Mesenchymal stem cells (MSCs) are non-hematopoietic progenitor cells that may be extracted from bone marrow, tooth pulp, adipose tissue and placenta/umbilical cord blood dealing with adult stem cells. MSCs are mostly involved in regeneration of tissue, they have also been shown to preferentially migrate to location of several types of tumor in-vivo ...
April 23, 2024: Journal of Drug Targeting
#11
JOURNAL ARTICLE
Chuanwang Yang, Zhe Cheng, Pengju Li, Bozhi Tian
ConspectusElectrical neuromodulation has achieved significant translational advancements, including the development of deep brain stimulators for managing neural disorders and vagus nerve stimulators for seizure treatment. Optoelectronics, in contrast to wired electrical systems, offers the leadless feature that guides multisite and high spatiotemporal neural system targeting, ensuring high specificity and precision in translational therapies known as "photoelectroceuticals". This Account provides a concise overview of developments in novel optoelectronic nanomaterials that are engineered through innovative molecular, chemical, and nanostructure designs to facilitate neural interfacing with high efficiency and minimally invasive implantation...
April 23, 2024: Accounts of Chemical Research
#12
REVIEW
Laura Zucconi, Giorgia Cavallini, Fabiana Canini
Antarctic soils represent one of the most pristine environments on Earth, where highly adapted and often endemic microbial species withstand multiple extremes. Specifically, fungal diversity is extremely low in Antarctic soils and species distribution and diversity are still not fully characterized in the continent. Despite the unique features of this environment and the international interest in its preservation, several factors pose severe threats to the conservation of inhabiting ecosystems. In this light, we aimed to provide an overview of the effects on fungal communities of the main changes endangering the soils of the continent...
April 23, 2024: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
#13
JOURNAL ARTICLE
Zhi Zhang, Guoshuai Zhang, Xinke Zhang, Huihui Zhang, Junbo Xie, Rui Zeng, Baolin Guo, Linfang Huang
Eomecon chionantha Hance, an endemic species in China, has a long medical history in Chinese ethnic minority medicine and is known for its anti-inflammatory and analgesic effects. However, studies of E. chionantha are lacking. In this study, we investigated the characteristics of the E. chionantha chloroplast genome and determined the taxonomic position of E. chionantha in Papaveraceae via phylogenetic analysis. In addition, we determined molecular markers to identify E. chionantha at the molecular level by comparing the chloroplast genomes of E...
April 23, 2024: Journal of Plant Research
#14
REVIEW
Amirhossein Bahmanpour, Seyed Majid Ghoreishian, Azadeh Sepahvandi
There are numerous effective procedures for cell signaling, in which humans directly transmit detectable signals to cells to govern their essential behaviors. From a biomedical perspective, the cellular response to the combined influence of electrical and magnetic fields holds significant promise in various domains, such as cancer treatment, targeted drug delivery, gene therapy, and wound healing. Among these modern cell signaling methods, electromagnetic fields (EMFs) play a pivotal role; however, there remains a paucity of knowledge concerning the effects of EMFs across all wavelengths...
April 23, 2024: Annals of Biomedical Engineering
#15
REVIEW
Amy Coop, Amelia Clark, John Morgan, Fiona Reid, J Hubert Lacey
PURPOSE: The SCOFF questionnaire was designed as a simple, memorable screening tool to raise suspicion that a person might have an eating disorder. It is over 20 years since the creation of the SCOFF, during which time it has been widely used. Considering this, we wish to review the use of the SCOFF in peer-reviewed scientific journals, and to assess whether it is being used appropriately in the manner in which it was originally devised and tested. METHODS: The Preferred Reporting Items for a Systematic Review and Meta-analysis (PRISMA) guidelines were followed, and all search strategies and methods were determined before the onset of the study...
April 23, 2024: Eating and Weight Disorders: EWD
#16
JOURNAL ARTICLE
Susan Benjamin Feingold, Barry M Lewis
PURPOSE: To prevent the incarceration and influence outcomes when criminal culpability is linked to postpartum psychosis. METHODS: Infanticide, neonaticide and filicide are most often linked with postpartum psychosis, which affects 1-2 women per 1,000 births or 4,000 women each year in the United States. Multiple genetic, hormonal and psychosocial factors surrounding childbirth result in a 1 to 4% risk of infanticide in women with postpartum psychosis. The authors seek to increase awareness of postpartum psychosis and postpartum depression in state legislatures...
April 23, 2024: Archives of Women's Mental Health
#17
JOURNAL ARTICLE
Elisabeth Mack, Peter Horak, Stefan Fröhling, Andreas Neubauer
Precision oncology is a field of personalized medicine in which tumor biology forms the basis for tailored treatments. The preferred approach currently applied in clinical practice is based on the concept of malignant tumors as genetic diseases that are caused by mutations in oncogenes and tumor suppressors. On the one hand, these can be targeted by molecular drugs, while on the other hand, next-generation sequencing allows for comprehensive analysis of all relevant aberrations, thus enabling the matching of appropriate treatments across entities based on molecular information...
April 23, 2024: Inn Med (Heidelb)
#18
JOURNAL ARTICLE
Zeng Cui, Jian Sun, Gao-Lin Wu
Plant diversity can significantly affect the grassland productivity and its stability. However, it remains unclear how plant diversity affects the spatial stability of natural grassland productivity, especially in alpine regions that are sensitive to climate change. We analyzed the interaction between plant (species richness and productivity, etc.) and climatic factors (precipitation, temperature, and moisture index, etc.) of alpine natural grassland on the Qinghai-Tibetan Plateau. In addition, we tested the relationship between plant diversity and spatial stability of grassland productivity...
April 23, 2024: Oecologia
#19
JOURNAL ARTICLE
Mert Erkan Basol, Roland Seifert
Naunyn-Schmiedeberg's Archives of Pharmacology is the oldest pharmacological journal, founded in 1873. This bibliometric analysis examines the pivotal transformations within Naunyn-Schmiedeberg's Archives of Pharmacology from 1947 to 1974, identifying significant shifts from a national focus to a period of extensive internationalization and English-language adoption. Employing Python and Beautiful Soup for data extraction from SpringerLink, the study maps the journal's trajectory through post-World War II development, highlighting the decline in publication rates due to its initial emphasis on German-language articles predominantly from Germany...
April 23, 2024: Naunyn-Schmiedeberg's Archives of Pharmacology
#20
JOURNAL ARTICLE
Attentional spatial cueing of the stop-signal affects the ability to suppress behavioural responses.
Md Tanbeer Haque, Mariella Segreti, Valentina Giuffrida, Stefano Ferraina, Emiliano Brunamonti, Pierpaolo Pani
The ability to adapt to the environment is linked to the possibility of inhibiting inappropriate behaviours, and this ability can be enhanced by attention. Despite this premise, the scientific literature that assesses how attention can influence inhibition is still limited. This study contributes to this topic by evaluating whether spatial and moving attentional cueing can influence inhibitory control. We employed a task in which subjects viewed a vertical bar on the screen that, from a central position, moved either left or right where two circles were positioned...
April 23, 2024: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
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