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Anxiety medications

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https://www.readbyqxmd.com/read/29332026/medicinal-plant-materials-in-the-treatment-of-anxiety-disorders-neurobiological-aspects
#1
Miłosz Jan Gołyszny, Ewa Obuchowicz
Context • Pathological anxiety, which affects approximately one-third of the world population, is an inadequate, irrational reaction of an organism to the environment and to a potential threat. Despite advancements in pharmacotherapy for anxiety disorders, further studies are still necessary to search for new substances possessing the desired anxiolytic effects, with as few unwanted effects as possible. Objective • This study intended to examine the characteristics of medicinal plant materials that exhibit anxiolytic properties, with a special emphasis on the mechanisms of action of their active ingredients on the systems involved in the pathophysiology of anxiety...
January 15, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29331971/a-study-protocol-for-a-non-randomised-comparison-trial-evaluating-the-feasibility-and-effectiveness-of-a-mobile-cognitive-behavioural-programme-with-integrated-coaching-for-anxious-adults-in-primary-care
#2
Eva Szigethy, Francis Solano, Meredith Wallace, Dina L Perry, Lauren Morrell, Kathryn Scott, Megan Jones Bell, Megan Oser
INTRODUCTION: Generalised anxiety disorder (GAD) and subclinical GAD are highly prevalent in primary care. Unmanaged anxiety worsens quality of life in patients seen in primary care practices and leads to increased medical utilisation and costs. Programmes that teach patients cognitive-behavioural therapy (CBT) techniques have been shown to improve anxiety and to prevent the evolution of anxiety symptoms to disorders, but access and engagement have hampered integration of CBT into medical settings...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29330598/satisfaction-in-rhinoplasty-the-possible-impact-of-anxiety-and-functional-outcome
#3
Serap Koybasi, Yusuf Ozgur Bicer, Sinan Seyhan, Selcan Kesgin
BACKGROUND: Rhinoplasty is a complex but commonly applied surgical procedure. Patient satisfaction is the least discussed but one of the most important determinants of surgical success. OBJECTIVES: Evaluation of the patient satisfaction together with surgeon satisfaction were the main goals of this study. The roles of anxiety, gender, age and follow-up period were also studied. PATIENTS AND METHODS: 53 eligible patients operated by the first two authors within the previous 2 years were enrolled in the study...
January 12, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29330217/a-systematic-review-of-network-meta-analyses-for-pharmacological-treatment-of-common-mental-disorders
#4
REVIEW
Taryn Williams, Dan J Stein, Jonathan Ipser
QUESTION: Network meta-analyses (NMAs) of treatment efficacy across different pharmacological treatments help inform clinical decision-making, but their methodological quality may vary a lot depending also on the quality of the included primary studies. We therefore conducted a systematic review of NMAs of pharmacological treatment for common mental disorders in order to assess the methodological quality of these NMAs, and to relate study characteristics to the rankings of efficacy and tolerability...
January 12, 2018: Evidence-based Mental Health
https://www.readbyqxmd.com/read/29329059/amyloid-burden-and-incident-depressive-symptoms-in-preclinical-alzheimer-s-disease
#5
Stephanie Perin, Karra D Harrington, Yen Ying Lim, Kathryn Ellis, David Ames, Robert H Pietrzak, Adrian Schembri, Stephanie Rainey-Smith, Olivier Salvado, Simon M Laws, Ralph N Martins, Victor L Villemagne, Christopher C Rowe, Colin L Masters, Paul Maruff
BACKGROUND: Relationships between depression and Alzheimer's disease (AD) may become clearer if studied in preclinical AD where dementia is not present. METHOD: The aim of this study was to evaluate prospectively, relationships between brain amyloid-β (Aβ), depressive symptoms and screen positive depression in cognitively normal (CN) older adults. Depressive symptoms were measured with the Geriatric Depression Inventory (GDS-15) in CN adults from the Australian Imaging Biomarkers and Lifestyle (AIBL) study without depression at baseline and classified as having abnormally high (Aβ+; n = 136) or low (Aβ-; n = 449) Aβ according to positron emission tomography at 18-month intervals over 72 months...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29327493/a-prospective-cohort-study-of-122-adult-patients-presenting-to-an-otolaryngologist-s-office-with-globus-pharyngeus
#6
Eva Rye Rasmussen, Didde Traerup Schnack, Andreas Tomaas Ravn
OBJECTIVES: To investigate the epidemiology of globus pharyngeus in adult patients presenting to the otolaryngologist's office. Also the predictors of persisting symptoms, prevalence of anxiety and the effect of clinical assessment were analyzed. DESIGN: This was a prospective cohort study. Follow-up was done using a postal questionnaire. SETTING: One otolaryngologists' office comprising three medical doctors. PARTICIPANTS: 122 consecutive globus patients presenting to one otolaryngology office in a one-year period...
January 11, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29327173/personality-traits-patient-centered-health-status-and-prognosis-of-brain-tumor-patients
#7
Adomas Bunevicius
Personality traits can be related to prognosis of cancer patients. The study aimed to evaluate the association of big-five personality dimensions with emotional and cognitive health status, and prognosis of brain tumor patients. A total of 178 patients admitted for brain tumor surgery were evaluated for personality traits (Tem item Personality Inventory), depressive/anxiety symptoms (Hospital Anxiety and Depression Scale or HADS) and cognitive functioning (Mini Mental State Examination or MMSE) on admission...
January 11, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29327085/acceptance-and-commitment-therapy-for-symptom-interference-in-metastatic-breast-cancer-patients-a-pilot-randomized-trial
#8
Catherine E Mosher, Ekin Secinti, Ruohong Li, Adam T Hirsh, Jonathan Bricker, Kathy D Miller, Bryan Schneider, Anna Maria Storniolo, Lida Mina, Erin V Newton, Victoria L Champion, Shelley A Johns
PURPOSE: Breast cancer is the leading cause of cancer mortality in women worldwide. With medical advances, metastatic breast cancer (MBC) patients often live for years with many symptoms that interfere with activities. However, there is a paucity of efficacious interventions to address symptom-related suffering and functional interference. Thus, this study examined the feasibility and preliminary efficacy of telephone-based acceptance and commitment therapy (ACT) for symptom interference with functioning in MBC patients...
January 12, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29326032/the-anxiolytic-effect-of-juniperus-virginiana-l-essential-oil-and-determination-of-its-active-constituents
#9
Kai Zhang, Lei Yao
Essential oil from Juniperus virginiana L. (eastern red cedarwood essential oil, CWO) has been used to relax mind and enhance comfort for medical purposes. Few reports showed its effect on anxiety behaviors in animal models. The present study investigated the anxiolytic effect of CWO using two anxiety tests in mice, then determined the major active constituents, examined the change of neurotransmitters after intraperitoneal (i.p.) administration. Analysis using GC/MS revealed that the CWO contained (-)-α-cedrene (28...
January 8, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29325791/the-therapeutic-effects-of-cannabis-and-cannabinoids-an-update-from-the-national-academies-of-sciences-engineering-and-medicine-report
#10
REVIEW
Donald I Abrams
The National Academies of Sciences, Engineering and Medicine conducted a rapid turn-around comprehensive review of recent medical literature on The Health Effects of Cannabis and Cannabinoids. The 16-member committee adopted the key features of a systematic review process, conducting an extensive search of relevant databases and considered 10,000 recent abstracts to determine their relevance. Primacy was given to recently published systematic reviews and primary research that studied one of the committee's 11 prioritized health endpoints- therapeutic effects; cancer incidence; cardiometabolic risk; respiratory disease; immune function; injury and death; prenatal, perinatal and postnatal outcomes; psychosocial outcomes; mental health; problem Cannabis use; and Cannabis use and abuse of other substances...
January 8, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29325731/pharmacogenomic-testing-in-child-and-adolescent-psychiatry-an-evidence-based-review
#11
Anna M Wehry, Laura Ramsey, Shane E Dulemba, Sarah A Mossman, Jeffrey R Strawn
Significant advances have been made in the application of pharmacogenomic testing for the treatment of patients with psychiatric disorders. Over the past decade, a number of studies have evaluated the utility of pharmacogenomic testing in pediatric patients with psychiatric disorders. The evidence base for pharmacogenomic testing in youth with depressive and anxiety disorders as well as attention/deficit hyperactivity disorder (ADHD) is reviewed in this article. General pharmacogenomic principles are summarized and functional polymorphisms in P450 enzymes (and associated metabolizer phenotypes), the serotonin transporter promoter polymorphisms, serotonin 2 A receptor genes (e...
January 8, 2018: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/29325492/illness-perception-is-significantly-determined-by-depression-and-anxiety-in-systemic-lupus-erythematosus
#12
K Nowicka-Sauer, A Hajduk, H Kujawska-Danecka, D Banaszkiewicz, Ż Smoleńska, Z Czuszyńska, J Siebert
Objectives Illness perception is a cognitive representation influencing physical and psychological functioning and adherence in patients with rheumatic disease. Studies exploring illness perception in systemic lupus erythematosus (SLE) are still scarce and none of them have investigated factors determining illness perception. We aimed to assess illness perception and to identify psychological, clinical and sociodemographic factors that might influence illness perception in SLE. Methods The study involved 80 patients with SLE (87...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29325238/psychometrics-of-the-self-report-concise-associated-symptoms-tracking-scale-cast-sr-results-from-the-stride-ctn-0037-study
#13
Joseph M Trombello, Michael O Killian, Allen Liao, Katherine Sanchez, Tracy L Greer, Robrina Walker, Bruce Grannemann, Chad D Rethorst, Thomas Carmody, Madhukar H Trivedi
OBJECTIVE: The self-report Concise Associated Symptoms Tracking Scale (CAST-SR) was developed to track mania, irritability, anxiety, panic, and insomnia symptoms among depressed outpatients receiving antidepressant medication. Given the overlap between these domains, depression, and stimulant use disorders, we reexamined CAST-SR psychometrics in a novel sample: individuals with stimulant use disorder receiving aerobic exercise or health education interventions. METHODS: Using the subsample of stimulant-dependent (following DSM-IV criteria) individuals prescribed antidepressants (N = 124) from the multisite Stimulant Reduction Intervention Using Dosed Exercise (CTN-0037) trial (total sample N = 302), conducted July 2010 to February 2013, we analyzed CAST-SR data collected at the first assessment after participant's discharge from residential treatment...
January 9, 2018: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29324396/cyberchondria-overlap-with-health-anxiety-and-unique-relations-with-impairment-quality-of-life-and-service-utilization
#14
Brittany M Mathes, Aaron M Norr, Nicholas P Allan, Brian J Albanese, Norman B Schmidt
Cyberchondria refers to a clinical phenomenon in which repeated Internet searches regarding medical information result in excessive concerns about physical health. Cyberchondria is positively associated with symptoms of health anxiety, though it remains unclear as to whether cyberchondria poses a unique public burden. The current study replicated previous findings regarding the relationship between cyberchondria and health anxiety, and extended those findings to examine the extent to which health anxiety and cyberchondria may be differentially associated with public health outcomes, including impairment, quality of life, and service utilization...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29321706/validity-and-reliability-of-the-turkish-version-of-the-multiple-sclerosis-related-symptom-checklist
#15
Zeliha Tülek, Cansu Polat, Murat Kürtüncü, Mefkure Eraksoy
Introduction: Multiple sclerosis (MS) is a disease that causes different symptoms in each attack and has an individual-specific course. Detailed questioning and recording of MS symptoms is important for developing a management plan for individual-specific symptoms. The present study was planned to evaluate the validity and reliability of the Turkish version of "Multiple Sclerosis-Related Symptom Checklist" (MS-RS), which has been developed for patients to personally follow-up the symptoms they experience...
December 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/29321703/executive-functions-of-obsessive-compulsive-disorder-and-panic-disorder-patients-in-comparison-to-healty-controls
#16
Emel Kurt, Erol Yildirim, Volkan Topçuoğlu
Introduction: Patients with obsessive compulsive disorder (OCD) have impaired cognitive functions, including attention, verbal and visual memory, and visual-spatial abilities as well as executive function But some studies did not show any disturbance in executive function of patients with OCD. To date, only few studies have been conducted on neuropsychological functioning of patients with panic disorder (PD). There are limited studies to reach a definite conclusion on executive functions of patients with OCD and those with PD...
December 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/29320976/the-mediational-role-of-helplessness-in-psychological-outcomes-in-systemic-lupus-erythematosus
#17
S D Mills, D Azizoddin, S Gholizadeh, G Z Racaza, P M Nicassio
Objective Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can result in disability and psychological distress. Although pain has been associated with depressive symptomatology and stress in SLE, a paucity of theoretical models have been used to explain the relationship between pain and psychological distress in this population. Thus, the present study examined helplessness as a mediator of the relationship between pain and psychological distress among patients with SLE. Methods Multiple mediation analysis was used to examine the hypothesis that learned helplessness mediates the relationship between pain and symptoms of anxiety, depression, and stress in a sample of patients with SLE ( N = 136) receiving medical care at Cedars Sinai Medical Center...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29320917/hypoesthesia-in-generalised-anxiety-disorder-and-major-depression-disorder
#18
Ana García-Blanco, Pablo González-Valls, Carmen Iranzo-Tatay, Luis Rojo-Moreno, Pilar Sierra, Lorenzo Livianos
OBJECTIVE: The determination of soft signs can be a conducive practice to understand the differential etiology between depression and anxiety. This study aims at examining malleolar hypoesthesia role in distinguishing between patients with generalised anxiety disorder (GAD) and major depression disorder (MDD). METHODS: This study examines the presence of malleolar hypoesthesia in patients with GAD (n = 47) compared to patients with MDD (n = 48) and healthy individuals (controls; n = 99)...
January 10, 2018: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/29320382/two-new-psychotherapy-studies-back-to-the-future
#19
Eric M Plakun
This column reviews 2 recent high-quality psychotherapy research studies. One study by Steinert and colleagues suggests that psychodynamic therapy is equivalent to cognitive behavioral therapy (CBT) (or medication when this was the comparator) for a range of disorders. A second study by Barlow and colleagues finds Unified Protocol CBT targeting underlying emotional dysregulation to be equivalent to single disorder-specific CBT for a range of anxiety disorders. Taken together, these studies help bridge the gap between CBT and psychodynamic therapy and refocus us on the realities of clinical settings, where most patients present with multiple comorbid disorders...
January 2018: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/29319145/medical-students-knowledge-attitudes-and-behaviours-related-to-substance-use-in-lebanon-a-cross-sectional-survey
#20
Georges Assaf, Samar Noureddine, Silva P Kouyoumdjian, Jamil El Khoury
The study aims were to explore the knowledge, attitudes and behaviours of Lebanese medical students related to substance use and to determine prevalence and psychosocial predictors. A cross-sectional survey of 231 medical students (48.6% male; 53.1% preclinical, 46.9% clinical) was conducted during June 2012-July 2013. The questionnaire addressed knowledge and attitudes about substance use, religiosity, depression, anxiety and demographic characteristics. The knowledge score was 52.7% (standard deviation 14...
January 2, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
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