Zhe Jay Chen, X Allen Li, David J Brenner, Taran P Hellebust, Peter Hoskin, Michael C Joiner, Christian Kirisits, Ravinder Nath, Mark J Rivard, Bruce R Thomadsen, Marco Zaider
Brachytherapy utilizes a multitude of radioactive sources and treatment techniques that often exhibit widely different spatial and temporal dose delivery patterns. Biophysical models, capable of modeling the key interacting effects of dose delivery patterns with the underlying cellular processes of the irradiated tissues, can be a potentially useful tool for elucidating the radiobiological effects of complex brachytherapy dose delivery patterns and for comparing their relative clinical effectiveness. While the biophysical models have been used largely in research settings by experts, it has also been used increasingly by clinical medical physicists over the last two decades...
May 9, 2024: Medical Physics