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https://www.readbyqxmd.com/read/29100252/guidelines-regarding-%C3%A2-16-of-the-german-transplantation-act-initial-experiences-with-structured-reporting
#1
Daniel Pinto Dos Santos, Gordon Arnhold, Peter Mildenberger, Christoph Düber, Roman Kloeckner
Purpose To transfer the report sheet from the guidelines regarding the German Transplantation Act to a standards-compliant report template and to evaluate it in the clinical routine. Materials and Methods The template was developed using the freely available software brackets.io. It was implemented in the clinical routine using a reporting platform developed in-house. Interfaces to the department RIS and PACS allowed for integration into the usual reporting workflow. The evaluation period was 70 days. Results Developing the template for implementation of the guidelines was possible without any difficulties...
December 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29073168/coronary-endothelial-function-is-better-in-healthy-premenopausal-women-than-in-healthy-older-postmenopausal-women-and-men
#2
Lena Mathews, Micaela Iantorno, Michael Schär, Gabriele Bonanno, Gary Gerstenblith, Robert G Weiss, Allison G Hays
BACKGROUND: Premenopausal women have fewer cardiovascular disease (CVD) events than postmenopausal women and age-matched men, but the reasons are not fully understood. Coronary endothelial function (CEF), a barometer of coronary vascular health, promises important insights into age and sex differences in atherosclerotic CVD risk, but has not been well characterized in healthy individuals because of the invasive nature of conventional CEF measurements. Recently developed magnetic resonance imaging (MRI) methods were used to quantify CEF (coronary area and flow changes in response to isometric handgrip exercise (IHE), an endothelial-dependent stressor) to test the hypothesis that healthy women have better CEF compared to men particularly at a younger age...
2017: PloS One
https://www.readbyqxmd.com/read/28970412/exploration-of-learning-during-an-international-health-elective-using-photovoice-methodology
#3
Amy Werremeyer, Elizabeth Skoy, Gina Aalgaard Kelly
Based on surveys and structured interviews, International Health Experiences (IHEs) improve cultural sensitivity, communication, and self-confidence among health professions students. However, open-ended methods to explore student learning during an IHE are not widely utilized. We sought to explore pharmacy student-identified learning during an IHE in an open-ended fashion using Photovoice methodology. Pharmacy students on an IHE in Guatemala were given disposable cameras and asked to photograph images that reflected their learning...
November 29, 2016: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28846046/the-use-of-simulated-altitude-techniques-for-beneficial-cardiovascular-health-outcomes-in-nonathletic-sedentary-and-clinical-populations-a-literature-review
#4
Catherine A Lizamore, Michael J Hamlin
Lizamore, Catherine A., and Michael J. Hamlin. The use of simulated altitude techniques for beneficial cardiovascular health outcomes in nonathletic, sedentary, and clinical populations: A literature review. High Alt Med Biol 00:000-000, 2017. BACKGROUND: The reportedly beneficial improvements in an athlete's physical performance following altitude training may have merit for individuals struggling to meet physical activity guidelines. AIM: To review the effectiveness of simulated altitude training methodologies at improving cardiovascular health in sedentary and clinical cohorts...
August 28, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28837211/special-topic-interoperability-and-ehr-combining-openehr-snomed-ihe-and-continua-as-approaches-to-interoperability-on-national-ehealth
#5
Mate Beštek, Dalibor Stanimirović
OBJECTIVES: The main aims of the paper comprise the characterization and examination of the potential approaches regarding interoperability. This includes openEHR, SNOMED, IHE, and Continua as combined interoperability approaches, possibilities for their incorporation into the eHealth environment, and identification of the main success factors in the field, which are necessary for achieving required interoperability, and consequently, for the successful implementation of eHealth projects in general...
August 9, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28796600/interoperable-end-to-end-remote-patient-monitoring-platform-based-on-ieee-11073-phd-and-zigbee-health-care-profile
#6
Malcolm Clarke, Joost de Folter, Vivek Verma, Hulya Gokalp
This paper describes the implementation of an end-to-end remote monitoring platform based on the IEEE 11073 standards for Personal Health Devices (PHD). It provides an overview of the concepts and approaches and describes how the standard has been optimized for small devices with limited resources of processor, memory and power and that use short range wireless technology. It explains aspects of IEEE 11073, including the Domain Information Model, state model and nomenclature, and how these support its plug-and-play architecture...
August 7, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28679397/local-coronary-wall-eccentricity-and-endothelial-function-are-closely-related-in-patients-with-atherosclerotic-coronary-artery-disease
#7
Allison G Hays, Micaela Iantorno, Michael Schär, Monica Mukherjee, Matthias Stuber, Gary Gerstenblith, Robert G Weiss
BACKGROUND: Coronary endothelial function (CEF) in patients with coronary artery disease (CAD) varies among coronary segments in a given patient. Because both coronary vessel wall eccentricity and coronary endothelial dysfunction are predictors of adverse outcomes, we hypothesized that local coronary endothelial dysfunction is associated with local coronary artery eccentricity. METHODS: We used 3 T coronary CMR to measure CEF as changes in coronary cross-sectional area (CSA) and coronary blood flow (CBF) during isometric handgrip exercise (IHE), a known endothelial-dependent stressor, in 29 patients with known CAD and 16 healthy subjects...
July 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28601027/a-semantic-interoperability-approach-to-support-integration-of-gene-expression-and-clinical-data-in-breast-cancer
#8
Raul Alonso-Calvo, Sergio Paraiso-Medina, David Perez-Rey, Enrique Alonso-Oset, Ruud van Stiphout, Sheng Yu, Marian Taylor, Francesca Buffa, Carlos Fernandez-Lozano, Alejandro Pazos, Victor Maojo
INTRODUCTION: The introduction of omics data and advances in technologies involved in clinical treatment has led to a broad range of approaches to represent clinical information. Within this context, patient stratification across health institutions due to omic profiling presents a complex scenario to carry out multi-center clinical trials. METHODS: This paper presents a standards-based approach to ensure semantic integration required to facilitate the analysis of clinico-genomic clinical trials...
August 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28514150/correction-to-photocycle-of-photoactive-yellow-protein-in-cell-mimetic-environments-molecular-volume-changes-and-kinetics
#9
Cheolhee Yang, Seong Ok Kim, Yonggwan Kim, So Ri Yun, Jungkweon Choi, Hyotcherl Ihee
No abstract text is available yet for this article.
May 17, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28508818/biosignals-standards-and-fhir-the-way-to-go
#10
Stefan Sauermann, Veronika David, Alois Schlögl, Reinhard Egelkraut, Matthias Frohner, Birgit Pohn, Philipp Urbauer, Alexander Mense
BACKGROUND: Standards have become available to share semantically encoded vital parameters from medical devices, as required for example by personal healthcare records. Standardised sharing of biosignal data largely remains open. OBJECTIVES: The goal of this work is to explore available biosignal file format and data exchange standards and profiles, and to conceptualise end-to-end solutions. METHODS: The authors reviewed and discussed available biosignal file format standards with other members of international standards development organisations (SDOs)...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28479549/patient-summaries-in-context-of-large-scale-ehr-networks-with-fine-granular-access-control-restrictions
#11
Patrick Mangesius, Samrend Saboor, Thomas Schabetsberger
BACKGROUND: Large Scale Electronic Health Record (EHR) systems tend to contain a significant higher amount of patient data compared to traditional local Electronic Medical Record (EMR) silos. This demands the requirement of providing a user context and role specific summary of the patient record. Security and Access Control systems are a crucial part of modern EHR systems controlling legal policies and patient consents. Goal of this paper is to elaborate a concept enhancing an already existing, commonly based on IHE XDS and XACML based, EHR systems with summarization functionalities...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28405591/svd-aided-pseudo-principal-component-analysis-a-new-method-to-speed-up-and-improve-determination-of-the-optimum-kinetic-model-from-time-resolved-data
#12
Key Young Oang, Cheolhee Yang, Srinivasan Muniyappan, Jeongho Kim, Hyotcherl Ihee
Determination of the optimum kinetic model is an essential prerequisite for characterizing dynamics and mechanism of a reaction. Here, we propose a simple method, termed as singular value decomposition-aided pseudo principal-component analysis (SAPPA), to facilitate determination of the optimum kinetic model from time-resolved data by bypassing any need to examine candidate kinetic models. We demonstrate the wide applicability of SAPPA by examining three different sets of experimental time-resolved data and show that SAPPA can efficiently determine the optimum kinetic model...
July 2017: Structural Dynamics (Melville, N.Y.)
https://www.readbyqxmd.com/read/28375690/ultrafast-x-ray-crystallography-and-liquidography
#13
Hosung Ki, Key Young Oang, Jeongho Kim, Hyotcherl Ihee
Time-resolved X-ray diffraction provides direct information on three-dimensional structures of reacting molecules and thus can be used to elucidate structural dynamics of chemical and biological reactions. In this review, we discuss time-resolved X-ray diffraction on small molecules and proteins with particular emphasis on its application to crystalline (crystallography) and liquid-solution (liquidography) samples. Time-resolved X-ray diffraction has been used to study picosecond and slower dynamics at synchrotrons and can now access even femtosecond dynamics with the recent arrival of X-ray free-electron lasers...
May 5, 2017: Annual Review of Physical Chemistry
https://www.readbyqxmd.com/read/28364029/intact-blood-pressure-but-not-sympathetic-responsiveness-to-sympathoexcitatory-stimuli-in-a-patient-with-unilateral-carotid-body-resection
#14
Kathryn F Larson, Jacqueline K Limberg, Sarah E Baker, Michael J Joyner, Timothy B Curry
Despite rapidly growing interest in the therapeutic resection of the carotid body (CB) chemoreceptors, few physiologic studies exist on the consequences of unilateral CB resection. We present a case of an otherwise healthy postmenopausal female who underwent unilateral CB resection for a paraganglioma. Approximately 4 years postoperatively, she underwent analysis of her sympathetic and hemodynamic responses to hypoxia, lower body negative pressure, cold pressor test (CPT), and ischemic hand grip exercise and postexercise ischemia (IHE/PEI)...
April 2017: Physiological Reports
https://www.readbyqxmd.com/read/28353539/coronary-artery-endothelial-dysfunction-is-present-in-hiv-positive-individuals-without-significant-coronary-artery-disease
#15
Micaela Iantorno, Michael Schär, Sahar Soleimanifard, Todd T Brown, Richard Moore, Patricia Barditch-Crovo, Matthias Stuber, Shenghan Lai, Gary Gerstenblith, Robert G Weiss, Allison G Hays
OBJECTIVE: HIV-positive (HIV+) individuals experience an increased burden of coronary artery disease (CAD) not adequately accounted for by traditional CAD risk factors. Coronary endothelial function (CEF), a barometer of vascular health, is depressed early in atherosclerosis and predict future events but has not been studied in HIV+ individuals. We tested whether CEF is impaired in HIV+ patients without CAD as compared with an HIV-negative (HIV-) population matched for cardiac risk factors...
June 1, 2017: AIDS
https://www.readbyqxmd.com/read/28255789/-incidental-findings-evaluation-management-recommendations-and-legal-considerations
#16
P Mildenberger
Incidental findings are part of the routine radiological reporting workflow and describe findings which are not primarily the focus of the clinical context or the request of the referring physician. The clinical implications of such incidental findings can be very different, for example simple renal cysts or space-occupying lesions suspected of being tumors. A categorization of clinical findings according to the clinical relevance is therefore recommended. Documentation and communication of clinically relevant incidental findings are a part of the radiological reporting process and essential for reduction of the medicolegal risk...
April 2017: Der Radiologe
https://www.readbyqxmd.com/read/28210482/delayed-interval-delivery-can-save-the-second-twin-evidence-from-a-systematic-review
#17
REVIEW
S Feys, Y Jacquemyn
BACKGROUND: In case of preterm birth in twins, it is not well established if the second twin benefits from a delayed-interval delivery. OBJECTIVE: The main objective of this systematic review is to evaluate survival benefit of the second twin from delayed interval delivery compared to the first twin. Secondly, we will evaluate the survival benefit of the procedure when performed equal to or after 24 weeks gestational age of the first born. METHODS: Delayed interval delivery was defined as every attempt to perform a delayed interval delivery with at minimum placement of a high ligature of the umbilical cord and a delay of delivery of at least 24 hours...
December 2016: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/28193464/igas-a-framework-for-using-electronic-intraoperative-medical-records-for-genomic-discovery
#18
Matthew A Levin, Thomas T Joseph, Janina M Jeff, Rajiv Nadukuru, Stephen B Ellis, Erwin P Bottinger, Eimear E Kenny
OBJECTIVE: Design and implement a HIPAA and Integrating the Healthcare Enterprise (IHE) profile compliant automated pipeline, the integrated Genomics Anesthesia System (iGAS), linking genomic data from the Mount Sinai Health System (MSHS) BioMe biobank to electronic anesthesia records, including physiological data collected during the perioperative period. The resulting repository of multi-dimensional data can be used for precision medicine analysis of physiological readouts, acute medical conditions, and adverse events that can occur during surgery...
February 10, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28131837/acute-improvement-of-endothelial-functions-after-oral-ingestion-of-isohumulones-bitter-components-of-beer
#19
RANDOMIZED CONTROLLED TRIAL
Junko Tomita, Seiichi Mochizuki, Sohachi Fujimoto, Naoki Kashihara, Takashi Akasaka, Mitsune Tanimoto, Kiyoshi Yoshida
Isohumulones, principal components of the bitter taste of beers, have antioxidant capacity. We studied i) the effects of oral ingestion of isomerized hop extract (IHE) on the endothelial functions in smokers as well as non-smokers and ii) the effects of IHE on cultured endothelial cells in high oxidative stress state. Twelve cigarette smokers and eleven non-smokers ingested IHE and placebo in a randomized crossover design. Flow-mediated vasodilatation (FMD) was measured using ultrasonography. We also studied the effects of isohumulones on i) the cell viability under hypoxia and ii) the levels of angiotensin II (AT-II)-induced reactive oxygen species (ROS) in the cultured human aortic endothelial cells (HAECs)...
March 18, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28063135/cost-effectiveness-of-insulin-degludec-plus-liraglutide-ideglira-in-a-fixed-combination-for-uncontrolled-type-2-diabetes-mellitus-in-sweden
#20
Åsa Ericsson, Adam Lundqvist
BACKGROUND: Patients with uncontrolled type 2 diabetes mellitus (T2DM) are a priority group for intensified therapy without weight gain and with low risk of hypoglycaemia. OBJECTIVE: This study evaluates the cost effectiveness of insulin degludec plus liraglutide (IDegLira, Xultophy(®)) compared with six potential intensification treatment options for patients with T2DM that is uncontrolled with basal insulin. METHODS: The Swedish Institute for Health Economics (IHE) Cohort Model of Type 2 Diabetes was used with Swedish input data, a 40-year time frame and a societal perspective...
April 2017: Applied Health Economics and Health Policy
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