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Scabies

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https://www.readbyqxmd.com/read/28892427/norwegian-or-crusted-sarcoptic-mange-in-two-leishmanial-dogs
#1
Flora Kaltsogianni, Rania Farmaki, Alexander F Koutinas
Norwegian or crusted scabies (N/CS) is a rare skin disease with very few cases reported in the dog or the cat. Two adult, stray dogs were admitted in our clinic with a generalized, multifocal to diffuse and nonpruritic dermatitis that was characterized by severe crusting, scaling, and ulceration. In both instances, leishmaniosis and N/CS were diagnosed by immunofluorescent antibody test serology, lymph node cytology, and skin scrapings in which high numbers of Sarcoptes mites were found. The combination of miticidal and antileishmanial treatment, supported by topical treatment and nutritional support, resulted in the complete resolution of the skin lesions and spectacular improvement of the body condition in both cases...
September 11, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28890037/the-association-between-scabies-and-myasthenia-gravis-a-nationwide-population-based-cohort-study
#2
Ren-Jun Hsu, Chien-Yu Lin, Fung-Wei Chang, Chun-Fa Huang, Heng-Chang Chuang, Jui-Ming Liu
Scabies is an infectious inflammatory pruritic skin disease. Cytokine-mediated inflammatory processes contribute to the pathologic mechanism in scabies. Myasthenia gravis (MG) is also an autoimmune disease that is mediated by cytokines. The study aimed to investigate the association between scabies and myasthenia gravis. We conducted a nationwide population-based cohort study utilized data from the National Health Insurance Research Database (NHIRD) of Taiwan. Patients with scabies (n=5429) and control subjects without scabies (n=20,176) were enrolled...
September 7, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28883737/scabies-masquerading-as-bullous-pemphigoid-scabies-surrepticius
#3
Philip R Cohen
Scabies, a parasitic infestation caused by the mite Sarcoptes scabiei, is diagnosed by observing either the mite, its ova, or its excrement. The mite tracts, known as burrows and a characteristic presentation of the pruritic condition, are typically found on the web spaces between the fingers. Other cutaneous lesions include excoriated papules, pustules, and vesicles. However, atypical clinical variants of scabies, such as bullous, crusted, hidden, incognito, nodular, and scalp forms of the parasitic infestation, mimic the morphologic features of other non-parasitic dermatoses...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28879092/scabies
#4
Xiao Ke Liu, Jun Li
No abstract text is available yet for this article.
2017: IDCases
https://www.readbyqxmd.com/read/28868002/scabies-associated-with-granulomatous-dermatitis
#5
Jessica Harris, Rajiv Nathoo, Vladimir Vincek
Scabies is a relatively common parasitic infection, which has sometimes been associated with the formation of granuloma annulare. We report the case of an 86-year-old female who developed a non-necrotizing granulomatous dermatitis after a scabies infestation. This case highlights the importance of considering scabies in the differential diagnosis when granulomatous dermatitis is noted histologically that cannot be explained by other causes.
May 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28859974/novel-stat1-mutation-disrupts-small-ubiquitin-related-modifier-sumo-conjugation-causing-gain-of-function
#6
Elizabeth P Sampaio, Li Ding, Stacey R Rose, Phillip Cruz, Amy P Hsu, Anuj Kashyap, Lindsey B Rosen, Margery Smelkinson, Tatyana A Tavella, Elise M N Ferre, Meredith K Wierman, Christa S Zerbe, Michail S Lionakis, Steven M Holland
BACKGROUND: Sumoylation is a post-translational reversible modification of cellular proteins by the conjugation of SUMO (small ubiquitin-related modifier) and comprises an important regulator of protein function. OBJECTIVE: To characterize the molecular mechanism of a novel mutation at the SUMO motif on STAT1. METHODS: STAT1 sequencing and functional characterization were performed in transfection experiments using immunoblotting and immunoprecipitation in STAT1-deficient cell lines...
August 28, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28852108/expression-and-characterisation-of-a-sarcoptes-scabiei-protein-tyrosine-kinase-as-a-potential-antigen-for-scabies-diagnosis
#7
Nengxing Shen, Ran He, Yuqing Liang, Jing Xu, Manli He, Yongjun Ren, Xiaobin Gu, Weimin Lai, Yue Xie, Xuerong Peng, Guangyou Yang
Scabies is a disease that harms humans and other animals that is caused by the itch mite Sarcoptes scabiei burrowing into the stratum corneum of the skin. In the early stages of scabies, symptoms are often subclinical and there are no effective diagnostic methods. Herein, we cloned, expressed and characterised an S. scabiei protein tyrosine kinase (SsPTK) and evaluated its diagnostic value as a recombinant antigen in rabbit during the early stages of Sarcoptes infestation. The SsPTK protein is ~30 kDa, lacks a signal peptide, and shares high homology with a PTK from the rabbit ear mite Psoroptes ovis cuniculi...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28851633/acute-postinfectious-glomerulonephritis-associated-with-scabies-in-the-elderly-a-case-report
#8
Di Wang, Li Li, Lei Wei, Yingying Liu, Shiren Sun
Acute postinfectious glomerulonephritis (GN) secondary to scabies were mainly documented as early as in 1980s, and in all these published cases no histopathological evidence of renal biopsy were reported regarding scabies and renal damage. The delay in scabies treatment can result in a greater risk of secondary bacterial infections that can become invasive and/or lead to severe post-infective complications such as post-streptococcal glomerulonephritis. In diagnostic procedures, the clinical presentation of scabies is often atypical especially in elderly people patients...
August 26, 2017: Parasitology International
https://www.readbyqxmd.com/read/28833468/scabies-in-babies
#9
Taryn A Hill, Bernard Cohen
The clinical manifestations of scabies infestation vary according to age, making the diagnosis challenging, particularly for primary care providers and dermatologists who do not routinely care for young children. We present seven cases of newborns and infants who developed inflammatory burrows and nodules early in the course, which is not typical of the eruption seen in older children and adults. We review the cutaneous features, differential diagnosis, and treatment recommendations for scabies in different age groups...
August 22, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28829832/allergen-homologs-in-the-euroglyphus-maynei-draft-genome
#10
S Dean Rider, Marjorie S Morgan, Larry G Arlian
Euroglyphus maynei is a house dust mite commonly found in homes worldwide and is the source of allergens that sensitize and induce allergic reactions in humans. It is the source of species-specific allergens as well as allergens that are cross-reactive with the allergens from house dust mites Dermatophagoides farinae and D. pteronyssinus, and the ectoparasitic scabies mite Sarcoptes scabiei. The genomics, proteomics and molecular biology of E. maynei and its allergens have not been as extensively investigated as those of D...
2017: PloS One
https://www.readbyqxmd.com/read/28800522/screening-for-infectious-diseases-among-asylum-seekers-newly-arrived-in-germany-in-2015-a%C3%A2-systematic-single-centre-analysis
#11
A Z Kortas, J Polenz, J von Hayek, S Rüdiger, W Rottbauer, U Storr, T Wibmer
OBJECTIVES: During the migrant crisis in 2015, Germany was the largest single recipient of new asylum seekers in Europe. The German asylum law requires a screening examination for certain infectious diseases in asylum seekers upon arrival. The aim of this work was to analyse the rate of certain infectious diseases among asylum seekers screened at a reception centre in Southern Germany. STUDY DESIGN: Retrospective medical record review. METHODS: Medical records of 2602 asylum seekers screened by a local public health authority in Germany in 2015 were systematically analysed...
August 8, 2017: Public Health
https://www.readbyqxmd.com/read/28797273/host-immune-responses-to-the-itch-mite-sarcoptes-scabiei-in-humans
#12
REVIEW
Sajad A Bhat, Kate E Mounsey, Xiaosong Liu, Shelley F Walton
Scabies is a parasitic disease due to infestation of skin by the burrowing mite Sarcoptes scabiei. Scabies is a major public health problem and endemic in resource poor communities worldwide affecting over 100 million people. Associated bacterial infections cause substantial morbidity, and in severe cases can lead to renal and cardiac diseases. Mite infestation of the skin causes localised cutaneous inflammation, pruritus, skin lesions, and allergic and inflammatory responses are mounted by the host against the mite and its products...
August 10, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28783773/clinical-inquiry-what-is-the-most-effective-treatment-for-scabies
#13
Jonathon J Campbell, Christopher P Paulson, Joan Nashelsky
Topical permethrin is the most effective treatment for classic scabies (strength of recommendation [SOR]: A, meta-analyses with consistent results). Topical lindane and crotamiton are inferior to permethrin but appear equivalent to each other and benzyl benzoate, sulfur, and natural synergized pyrethrins (SOR: B, limited randomized trials). Although not as effective as topical permethrin, oral ivermectin is an effective treatment compared with placebo (SOR: B, a single small randomized trial). Oral ivermectin may reduce the prevalence of scabies at one year in populations with endemic disease more than topical permethrin (SOR: B, a single randomized trial)...
August 2017: Journal of Family Practice
https://www.readbyqxmd.com/read/28771469/the-prevalence-and-association-with-health-related-quality-of-life-of-tungiasis-and-scabies-in-schoolchildren-in-southern-ethiopia
#14
Stephen L Walker, Eglantine Lebas, Valentina De Sario, Zeleke Deyasso, Shimelis N Doni, Michael Marks, Chrissy H Roberts, Saba M Lambert
BACKGROUND: The prevalence of skin disease in low and middle income countries is high and communicable skin diseases are a significant public health problem. Tungiasis is an ectoparasite infestation caused by the flea Tunga penetrans, which has a widespread geographical distribution. Tungiasis causes painful skin lesions and may affect activities of daily living. OBJECTIVE: We wished to determine the prevalence and impact of tungiasis and scabies in schoolchildren in southern Ethiopia...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28767353/crusted-scabies
#15
Marta Elosua-González, Elena García-Zamora
A 71-year-old man with cirrhosis presented to the emergency department with severe diffuse pruritus. Three months earlier, he had presented with erythematous and scaly skin on the scalp and hands. Two skin scrapings had not revealed mites, and he was treated with oral and topical glucocorticoids...
August 3, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28758268/noodle-pattern-a-new-dermoscopic-pattern-for-crusted-scabies-norwegian-scabies
#16
LETTER
S Chavez-Alvarez, A Villarreal-Martinez, G Argenziano, J Ancer-Arellano, J Ocampo-Candiani
No abstract text is available yet for this article.
July 31, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28754703/biosynthesis-and-evolution-of-coronafacoyl-phytotoxin-production-in-the-common-scab-pathogen-streptomyces-scabies
#17
Luke Bown, Yuting Li, Fabrice Berrué, Joost T P Verhoeven, Suzanne C Dufour, Dawn R D Bignell
Coronafacoyl phytotoxins are an important family of plant toxins that are produced by several different phytopathogenic bacteria, including the gammaproteobacterium Pseudomonas syringae and the actinobacterium Streptomyces scabies. The phytotoxins consist of coronafacic acid (CFA) linked via an amide bond to different amino acids or amino acid derivatives. Previous work suggested that S. scabies and P. syringae use distinct biosynthetic pathways for producing CFA, which is subsequently linked to its amino acid partner to form the complete phytotoxin...
July 28, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28722633/characterization-of-sarcoptes-scabiei-tropomyosin-and-paramyosin-immunoreactive-allergens-in-scabies
#18
Shumaila Naz, Marion Desclozeaux, Kate E Mounsey, Farhana Riaz Chaudhry, Shelley Walton
Scabies is a human skin disease due to the burrowing ectoparasite Sarcoptes scabiei var. hominis resulting in intense itching and inflammation and manifesting as a skin allergy. Because of insufficient mite material and lack of in vitro propagation system for antigen preparation, scabies is a challenging disease to develop serological diagnostics. For allergen characterization, full-length S. scabiei tropomyosin (Sar s 10) was cloned, expressed in pET-15b, and assessed for reactivity with IgE antibodies from human sera...
July 10, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722612/the-epidemiology-of-scabies-and-impetigo-in-relation-to-demographic-and-residential-characteristics-baseline-findings-from-the-skin-health-intervention-fiji-trial
#19
Lucia Romani, Margot J Whitfeld, Josefa Koroivueta, Mike Kama, Handan Wand, Lisi Tikoduadua, Meciusela Tuicakau, Aminiasi Koroi, Raijieli Ritova, Ross Andrews, John M Kaldor, Andrew C Steer
Scabies and associated impetigo are under-recognised causes of morbidity in many developing countries. To strengthen the evidence base for scabies control we undertook a trial of mass treatment for scabies. We report on the occurrence and predictors of scabies and impetigo in participants at baseline. Participants were recruited in six island communities and were examined for the presence of scabies and impetigo. In addition to descriptive analyses, logistic regression models were fit to assess the association between demographic variables and outcome of interest...
July 17, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28711102/liquid-nitrogen-cryotherapy-in-the-treatment-of-chronic-unresponsive-nodular-scabies
#20
Vijay Zawar, Manoj Pawar
No abstract text is available yet for this article.
August 2017: Journal of the American Academy of Dermatology
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