Xiaoxue Yang, Jiawei Li, Meiling Ren, Xuemei Pan, Huiling Liu, Jie Jiang, Man Li, Zhe Yang, Bingyu Han, Lina Ma, Jianlei Hao, Yuanyuan Duan, Zhinan Yin, Yan Xu, Zheng Xiang, Bin Wu
Primary Biliary Cholangitis (PBC) and Autoimmune Hepatitis (AIH) are autoimmune diseases that target hepatocytes and bile duct cells, respectively. Despite their shared autoimmune nature, the differences in immunologic characteristics between them remain largely unexplored. This study seeks to elucidate the unique immunological profiles of PBC and AIH, and to identify key differences. We comprehensively analyzed various T-cell subsets and their receptor expression in a cohort of 45 patients, including 27 PBC and 18 AIH cases...
April 23, 2024: Journal of Leukocyte Biology