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https://www.readbyqxmd.com/read/29657061/risk-factors-for-new-onset-atrial-fibrillation-a-focus-on-asian-populations
#1
Yanguang Li, Daniele Pastori, Yutao Guo, Yutang Wang, Gregory Y H Lip
The incidence of new-onset atrial fibrillation (NOAF) is increasing both in the Asian populations and Western countries. Several demographic and clinical risk factors were independently associated with NOAF, including ageing, male sex, obesity, obstructive sleep apnea syndrome, hypertension, coronary artery disease, renal dysfunction and heart failure. However, some differences in the incidence of NOAF, the prevalence of some risk factors and lifestyle or environmental conditions may exist between Asian and Western countries...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29622460/prevalence-and-clinical-characteristics-of-obstructive-and-central-dominant-sleep-apnea-in-candidates-of-catheter-ablation-for-atrial-fibrillation-in-japan
#2
Takashi Kohno, Takehiro Kimura, Koichi Fukunaga, Wakako Yamasawa, Taishi Fujisawa, Ryoma Fukuoka, Kazuaki Nakajima, Shin Kashimura, Akira Kunitomi, Yoshinori Katsumata, Takahiko Nishiyama, Nobuhiro Nishiyama, Yoshiyasu Aizawa, Keiichi Fukuda, Seiji Takatsuki
INTRODUCTION: We aimed to study the prevalence and types of sleep apnea (SA) as well as their clinical characteristics in atrial fibrillation (AF) ablation candidates in Japan. METHODS: Before catheter ablation, 197 consecutive AF patients (age: 60 ± 9 years, body mass index; 25.0 ± 3.0) were evaluated with portable polygraphy. We compared the clinical characteristics, according to the severity of SA as well as its types, as defined by the presence of obstruction and the mixed vs...
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29589988/laparoscopic-sleeve-gastrectomy-for-morbid-obesity-at-a-veterans-affairs-medical-center
#3
Matthew Skancke, Clint Schoolfield, Robert Grossman, Jennifer C Kerns, Nicole Abel, Fredrick Brody
BACKGROUND: Class III obesity is a global health emergency associated with an increase in the incidence of many other diseases such as type 2 diabetes mellitus, hypertension, hyperlipidemia, cancer, obstructive sleep apnea, nonalcoholic fatty liver disease, osteoarthritis, infertility, and mental health disorders. Minimal work has been published regarding the efficacy of laparoscopic sleeve gastrectomy (LSG) in the veteran population to surgically manage morbid obesity. DESIGN: Retrospective analysis of LSG performed at a Veterans Affairs Medical Center (VAMC) between 2010 and 2017...
March 28, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29556729/role-of-mineralocorticoid-receptors-in-obstructive-sleep-apnea-and-metabolic-syndrome
#4
REVIEW
Badhma Valaiyapathi, David A Calhoun
PURPOSE OF REVIEW: This review will summarize recent developments in the research on the mineralocorticoid receptor and its impact on obstructive sleep apnea and metabolic syndrome. RECENT FINDINGS: Aldosterone excess plays an important role in the association between resistant hypertension and obstructive sleep apnea. The prevalence of obesity is increasing rapidly worldwide and is especially common among patients with obstructive sleep apnea, resistant hypertension, and metabolic syndrome, suggesting probable mechanistic links between these three conditions...
March 19, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29503410/investigation-of-obstructive-sleep-apnea-using-portable-monitors-and-health-check-data-in-japanese-drivers
#5
Masako Ueyama, Hiroyuki Kokuto, Hitoshi Sugihara, Shinichi Oikawa, Fumio Suzuki, Hajime Goto, Shoji Kudoh
AIMS: The identification and appropriate management of commercial motor vehicle (CMV) drivers with unrecognized obstructive sleep apnea (OSA) is a major public health concern and priority; OSA among drivers has not been fully investigated in Japan, and a better understanding of this undiagnosed disease is warranted. Therefore, we evaluated the prevalence of OSA and the factors related to apnea-hypopnea index (AHI) in Japanese CMV drivers. METHODS: This retrospective study included 1309 Japanese CMV drivers aged 40-69 years...
March 5, 2018: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/29482805/comorbidities-in-a-community-sample-of-narcolepsy
#6
Alexander Cohen, Jay Mandrekar, Erik K St Louis, Michael H Silber, Suresh Kotagal
STUDY OBJECTIVE: To assess comorbidities in a community-based cohort of narcolepsy. METHODS: A 2000-2014 community-based narcolepsy cohort was identified in Olmsted County, Minnesota. Records were reviewed by a certified sleep specialist for accuracy of diagnosis, and comorbidities were extracted and analyzed. Comorbidities in narcolepsy subjects, both at diagnosis and upon follow-up, were compared with those in unaffected and age- and sex-matched cohort using conditional logistic regression...
March 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29474482/prevalence-of-several-somatic-diseases-depends-on-the-presence-and-severity-of-obstructive-sleep-apnea
#7
Ragnhild L Tveit, Sverre Lehmann, Bjørn Bjorvatn
STUDY OBJECTIVES: The objective was to investigate the prevalence of heart attack, angina pectoris, stroke, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, asthma and obesity in relation to the presence and severity of obstructive sleep apnea. METHODS: The sample consisted of 1887 patients, with mean age of 48.6 years (range 16-83 years), referred to a university hospital on suspicion of obstructive sleep apnea. The patients filled out a questionnaire asking whether they were previously diagnosed with the comorbidities in interest...
2018: PloS One
https://www.readbyqxmd.com/read/29435811/comparative-outcomes-of-bariatric-surgery-in-patients-with-impaired-mobility-and-ambulatory-population
#8
Gautam Sharma, Zubaidah Nor-Hanipah, Ivy N Haskins, Suriya Punchai, Andrew T Strong, Chao Tu, John H Rodriguez, Phillip R Schauer, Matthew Kroh
PURPOSE: This study aims to characterize complications, metabolic improvement, and change in ambulation status for patients with impaired mobility undergoing bariatric surgery. MATERIAL AND METHODS: Individuals undergoing primary sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) from February 2008 to December 2015 were included. Impaired mobility (WC) was defined as using a wheelchair or motorized scooter for at least part of a typical day. The WC group was propensity score matched to ambulatory patients (1:5 ratio)...
February 12, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29432207/prevalence-of-comorbid-conditions-pre-existing-and-diagnosed-at-a-tertiary-care-pediatric-weight-management-clinic
#9
Griselle Leon, Elizabeth de Klerk, Josephine Ho, Michelle Jackman, Raylene A Reimer, Kimberly E Connors, Paola Luca
BACKGROUND: Childhood obesity places individuals at risk for a multitude of physical and mental health problems. The aim of this study was to assess the prevalence of obesity related comorbidities diagnosed prior to and after attending a tertiary care pediatric weight management clinic. METHODS: A cross sectional retrospective chart review of patients 2-17 years old seen in the weight management clinic at Alberta Children's Hospital from May 2012 to May 2014. RESULTS: A total of 199 patients were included in the review...
February 13, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29425754/does-the-medical-comorbidity-profile-of-obstructive-sleep-apnea-patients-treated-with-maxillomandibular-advancement-differ-from-that-of-obstructive-sleep-apnea-patients-managed-nonsurgically
#10
Richard Ngo, Elaina Pullano, Zachary S Peacock, Edward T Lahey, Meredith August
PURPOSE: Obstructive sleep apnea (OSA) patients with retrognathia and measurable anatomic airway determinants may represent a subset of OSA patients and have distinct comorbidity profiles. Our aim was to compare the medical comorbidities of OSA patients managed surgically with maxillomandibular advancement with those of nonsurgical patients. PATIENTS AND METHODS: In this cross-sectional retrospective study, patients for both cohorts were identified through the Massachusetts General Hospital oral and maxillofacial surgery data registry and the Massachusetts General Hospital Research Patient Data Registry...
January 31, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29373256/severe-obstructive-sleep-apnea-in-children-with-elevated-blood-pressure
#11
Jane Hinkle, Heidi V Connolly, Heather R Adams, Marc B Lande
The objective was to determine the prevalence of habitual snoring and obstructive sleep apnea (OSA) in a cohort of children referred for elevated blood pressure (BP), and to determine the association between OSA and BP elevation, learning difficulties, and behavioral problems. We performed a retrospective review of 446 consecutive new patients referred for elevated BP. One hundred four (23%) had habitual snoring. Patients with habitual snoring were more likely to be obese (86.5 vs. 55.6%, P < .001) and to have Medicaid insurance (52...
January 3, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29368899/-obesity-hypoventilation-syndrome-and-pulmonary-hypertension-an-association-little-known-in-mexico
#12
Ernesto Díaz-Domínguez, Martín Rosas-Peralta, Luis Efrén Santos-Martínez, Nielzer Armando Rodríguez-Almendros, José Antonio Magaña-Serrano, Gilberto Pérez-Rodríguez
The obesity hypoventilation syndrome (OHS) refers to the combination of obesity, daytime hypercapnia and sleep-disordered breathing. Obesity has risen to epidemic proportions in the last three decades in the United States, Mexico and Europe. The OHS is associated with obstructive sleep apnea syndrome in 30%. Without treatment, mortality is 46% at 50 months. So in this paper we analyze the OHS, obesity and pulmonary hypertension, the pathophysiology, clinical presentation and diagnosis as well as the treatment, which is aimed at the correction of sleep-disordered breathing and hypoxemia; although there is little experience with the use of specific pulmonary vasodilator drugs...
January 2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29332673/prevalence-and-comorbidity-of-sleep-conditions-in-australian-adults-2016-sleep-health-foundation-national-survey
#13
Sarah L Appleton, Tiffany K Gill, Carol J Lang, Anne W Taylor, R Douglas McEvoy, Nigel P Stocks, David A González-Chica, Robert J Adams
OBJECTIVE: To determine the prevalence of sleep conditions (obstructive sleep apnea [OSA], insomnia symptoms, simple snoring, and restless legs) and their associated burden of chronic conditions in a community sample. DESIGN: Cross-sectional national adult online survey. SETTING: Community-based sample. PARTICIPANTS: Australian adults ≥18 years, N = 1011. MEASUREMENTS: A cross-sectional national online survey assessed diagnosed OSA, OSA symptoms, insomnia symptoms, sleep problems, excessive daytime sleepiness (Epworth Sleepiness Scale ≥11), and physician-diagnosed health conditions (heart disease, diabetes, hypertension, reflux disease, lung disease, depression, anxiety/panic disorder, arthritis)...
February 2018: Sleep Health
https://www.readbyqxmd.com/read/29319835/gastrisk-bypass-fyller-50-%C3%A3-r-fetmaoperationen-som-visade-sig-fungera-mot-diabetes
#14
Per Videhult
Mason performed the first gastric bypass (GBP) for obesity in 1967 after having observed substantial weight loss in patients operated for gastric ulcer.  The weight loss after GBP is 30 % and 2/3 of patients with type II diabetes can stop their medication. Half of the patients can stop medication for hypertension or hyperlipidemia, 75% are cured from reflux and obstructive sleep apnea. GBP prolongs survival especially among diabetics. Restriction and malabsorption is of minor importance for weight loss. The mechanisms underlying weight loss and diabetes remissions are endocrine...
January 9, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29315434/recognizable-clinical-subtypes-of-obstructive-sleep-apnea-across-international-sleep-centers-a-cluster-analysis
#15
Brendan T Keenan, Jinyoung Kim, Bhajan Singh, Lia Bittencourt, Ning-Hung Chen, Peter A Cistulli, Ulysses J Magalang, Nigel McArdle, Jesse W Mindel, Bryndis Benediktsdottir, Erna Sif Arnardottir, Lisa Kristin Prochnow, Thomas Penzel, Bernd Sanner, Richard J Schwab, Chol Shin, Kate Sutherland, Sergio Tufik, Greg Maislin, Thorarinn Gislason, Allan I Pack
Study Objectives: A recent study of patients with moderate-severe obstructive sleep apnea (OSA) in Iceland identified three clinical clusters based on symptoms and comorbidities. We sought to verify this finding in a new cohort in Iceland and examine the generalizability of OSA clusters in an international ethnically diverse cohort. Methods: Using data on 972 patients with moderate-severe OSA (apnea-hypopnea index [AHI] ≥ 15 events per hour) recruited from the Sleep Apnea Global Interdisciplinary Consortium (SAGIC), we performed a latent class analysis of 18 self-reported symptom variables, hypertension, cardiovascular disease, and diabetes...
March 1, 2018: Sleep
https://www.readbyqxmd.com/read/29306907/new-aspects-in-the-pathomechanism-of-diseases-of-civilization-particularly-psychosomatic-disorders-part-2-chronic-hypocapnia-and-hypercapnia-in-the-medical-practice
#16
Andras Sikter, Zoltan Rihmer, Roberto de Guevara
The authors seek to find new connections between recent results of biology and older theories. This paper aims to assemble the jigsaw puzzle. The theoretical background of the hypothesis was described in the previous issue of the journal (Sikter et al. 2017a). Human stress response often coexists with persistent hypocapnia or hypercapnia - developing via psychosomatic pathomechanism - which can lead to mental and psychosomatic illnesses. Chronic hypocapnia mainly generates hyperarousal disorders which may be reversible for an extended time, however, vicious cycles may start when hypoxia and/or severe somatic diseases are simultaneously present (commonly in the elderly), which conditions often end with death without medical help...
September 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/29298287/polysomnography-based-diagnosis-in-mexican-adult-patients-with-obstructive-sleep-apnea-syndrome-osas-clinical-suspicion
#17
Edgar Arrazola-Cortés, Josefina Hernández-Cervantes, Brenda González-Pérez, Sergio Sauri-Suárez, Luz Berenice López-Hernández, Christian Gabriel Toledo-Lozano, Vanessa Orellana-Villazón, Sofía Lizeth Alcaraz-Estrada, Silvia García
INTRODUCTION: Obstructive sleep apnea syndrome (OSA) occurs in 2-4% of adults, increasing by 2.5 times the risk of sudden death. OBJECTIVE: Establish the concordance of the clinical diagnostic and electrical diagnosis in an adult series that underwent polysomnography. MATERIALS AND METHODS: Patients with sleep disorders that underwent consecutively polysomnography recording. RESULTS: In this study, 51 subjects from 24 to 77 years old (54...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29249586/medium-to-long-term-outcomes-of-bariatric-surgery-in-older-adults-with-super-obesity
#18
Aly Elbahrawy, Alexandre Bougie, Sarah-Eve Loiselle, Sebastian Demyttenaere, Olivier Court, Amin Andalib
BACKGROUND: Indications and outcomes of bariatric surgery in older adults suffering from morbid obesity remain controversial. We aimed to evaluate safety and medium to long-term outcomes of bariatric procedures in this patient population. SETTING: University Hospital, Canada. METHODS: This is a single-center retrospective study of a prospectively collected database. We included patients aged ≥60 years who underwent sleeve gastrectomy, Roux-en-Y gastric bypass, or biliopancreatic diversion with duodenal switch between January 2006 and December 2014 and had at least 2 years of follow-up...
April 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29241747/pathophysiology-of-the-metabolic-syndrome
#19
Emma McCracken, Monica Monaghan, Shiva Sreenivasan
The metabolic syndrome-otherwise called syndrome X, insulin resistance syndrome, Reaven syndrome, and "the deadly quartet"-is the name given to the aggregate of clinical conditions comprising central and abdominal obesity, systemic hypertension, insulin resistance (or type 2 diabetes mellitus), and atherogenic dyslipidemia. It is a prothrombotic and proinflammatory state characterized by increased inflammatory cytokine activity. In addition to inflammatory dermatoses such as psoriasis, lichen planus, and hidradenitis suppurativa, metabolic syndrome is also commonly associated with accelerated atherosclerotic cardiovascular disease, hyperuricemia/gout, chronic kidney disease, and obstructive sleep apnea...
January 2018: Clinics in Dermatology
https://www.readbyqxmd.com/read/29227187/laparoscopic-sleeve-gastrectomy-endoscopic-findings-and-gastroesophageal-reflux-symptoms-at-18-month-follow-up
#20
Germán Viscido, Verónica Gorodner, Franco Signorini, Luciano Navarro, Lucio Obeide, Federico Moser
INTRODUCTION: Laparoscopic sleeve gastrectomy (LSG) has shown excellent results in terms of weight loss and resolution of comorbidities. Despite that, the effect of LSG on gastroesophageal reflux disease (GERD) is still a controversial topic. Our objective was to evaluate the presence of gastroesophageal reflux symptoms, erosive esophagitis (EE), and hiatal hernia (HH) in obese patients undergoing LSG. METHODS: Prospective observational study. LSG patients were studied before and at 18-month follow-up...
January 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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