E Seidl, J Carlens, S Reu, M Wetzke, J Ley-Zaporozhan, F Brasch, T Wesselak, A Schams, D Rauch, L Schuch, M Kappler, P Schelstraete, M Wolf, F Stehling, E Haarmann, D Borensztajn, M van de Loo, S Rubak, C Lex, B Hinrichs, K Reiter, N Schwerk, M Griese
BACKGROUND: Pulmonary interstitial glycogenosis (PIG) is a rare paediatric interstitial lung disease of unknown cause. The diagnosis can only be made by lung biopsy. Less than 100 cases have been reported. Clinical features, treatment and outcomes have rarely been assessed systematically in decent cohorts of patients. METHODS: In this retrospective multicentre study, the clinical presentation, radiologic findings, pattern of lung biopsy, extrapulmonary comorbidities, treatment and outcome of eleven children with PIG were collected systematically...
July 2018: Respiratory Medicine