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vitamin D and hypertension

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https://www.readbyqxmd.com/read/28286773/the-strategy-to-prevent-and-regress-the-vascular-calcification-in-dialysis-patients
#1
REVIEW
Nai-Ching Chen, Chih-Yang Hsu, Chien-Liang Chen
The high prevalence of arterial calcification in end-stage renal disease (ESRD) is far beyond the explanation by common cardiovascular risk factors such as aging, diabetes, hypertension, and dyslipidemia. The finding relies on the fact that vascular and valvular calcifications are predictors of cardiovascular diseases and mortality in persons with chronic renal failure. In addition to traditional cardiovascular risk factors such as diabetes mellitus and blood pressure control, other ESRD-related risks such as phosphate retention, excess calcium, and prolonged dialysis time also contribute to the development of vascular calcification...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28264782/pregnancy-outcome-and-ultraviolet-radiation-a-systematic-review
#2
REVIEW
Lauren Megaw, Tom Clemens, Chris Dibben, Richard Weller, Sarah Stock
BACKGROUND: Season and vitamin D are indirect and direct correlates of ultraviolet (UV) radiation and are associated with pregnancy outcomes. Further to producing vitamin D, UV has positive effects on cardiovascular and immune health that may support a role for UV directly benefitting pregnancy. OBJECTIVES: To investigate the effects of UV exposure on pregnancy; specifically fetal growth, preterm birth and hypertensive complications. METHODS: We conducted a systematic review of Medline, EMBASE, DoPHER, Global Health, ProQuest Public Health, AustHealth Informit, SCOPUS and Google Scholar to identify 537 citations, 8 of which are included in this review...
March 3, 2017: Environmental Research
https://www.readbyqxmd.com/read/28255001/physiology-and-pathophysiology-of-the-intrarenal-renin-angiotensin-system-an-update
#3
Tianxin Yang, Chuanming Xu
The renin-angiotensin system (RAS) has a pivotal role in the maintenance of extracellular volume homeostasis and blood pressure through complex mechanisms. Apart from the well known systemic RAS, occurrence of a local RAS has been documented in multiple tissues, including the kidney. A large body of recent evidence from pharmacologic and genetic studies, particularly those using various transgenic approaches to manipulate intrarenal levels of RAS components, has established the important role of intrarenal RAS in hypertension...
March 2, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28244294/vitamin-d-and-urinary-incontinence-among-korean-women-a-propensity-score-matched-analysis-from-the-2008-2009-korean-national-health-and-nutrition-examination-survey
#4
Hyo Serk Lee, Jun Ho Lee
A recent study investigated the role of vitamin D in urinary incontinence (UI). However, very few data are available on this topic. Therefore, we evaluated these relationships using nationally representative data from Korea. We included 6,451 women over the age of 20 years who had participated in the Korea National Health and Nutrition Examination Survey IV. We conducted a propensity-matched study by identifying women with UI. Women without UI, matched for menopause, number of pregnancies, hypertension, diabetes, body mass index, age, stroke, asthma, and chronic obstructive pulmonary disease, were selected as a control group at a 2:1 ratio...
April 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28230063/effects-of-calcium-plus-vitamin-d-supplementation-on-blood-pressure-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#5
REVIEW
L Wu, D Sun
The effect of calcium or vitamin D supplement on blood pressure (BP) has been explored in previous meta-analyses, but the results are conflicting. The combined efficacy of calcium and vitamin D on BP has not been systematically assessed. Thus, we conducted a meta-analysis of randomized controlled trials (RCTs) to explore the effect of calcium plus vitamin D (CaD) supplementation on changes of systolic blood pressure (SBP) and diastolic blood pressure among male and female participants (with and without diagnosed hypertension) aged 18 years or older...
February 23, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28217686/pregnancy-related-osteoporosis-and-spinal-fractures
#6
Ka Yeong Yun, Si Eun Han, Seung Chul Kim, Jong Kil Joo, Kyu Sup Lee
Pregnancy-related osteoporosis is a very rare condition characterized by the occurrence of fracture during pregnancy or the puerperium. Despite its relative rarity, it can be a dangerous condition that causes severe back pain, height loss and disability. Normal physiologic changes during pregnancy, genetic or racial difference, obstetrical history and obstetrical disease, such as preterm labor or pregnancy-induced hypertension, are presumed risk factors of pregnancy-related osteooporosis. However, exact etiology and pathogenesis are uncertain...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28179126/vitamin-d-deficiency-in-mothers-neonates-and-children
#7
Deena H Elsori, Majeda S Hammoud
Vitamin D is produced in response to the exposure of skin to sunlight through UV-B synthesis. It can also be obtained from diet and dietary supplements. Vitamin D is essential for strong bones as it helps to absorb calcium from diet. Vitamin D deficiency mainly occurs if strict vegetarian diet is followed as mostly the source of vitamin D is animal based; therefore, exposure to sunlight is restricted or having dark skin color. Low vitamin D levels results in increased possibility of gestational diabetes among pregnant women, low birth weight and pre-eclampsia in infants, and mothers may suffer bone impairment, osteoporosis, hypocalcaemia, and hypertension...
February 5, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28160246/hypogonadotropic-hypogonadism-in-males-with-glycogen-storage-disease-type-1
#8
Evelyn M Wong, Anna Lehman, Philip Acott, Jane Gillis, Daniel L Metzger, Sandra Sirrs
BACKGROUND: Glycogen storage disease type 1 is an autosomal recessive disorder with an incidence of 1 in 100,000. Long-term complications include chronic blood glucose lability, lactic academia, short stature, osteoporosis, delayed puberty, gout, progressive renal insufficiency, systemic or pulmonary hypertension, hepatic adenomas at risk for malignant transformation, anemia, vitamin D deficiency, hyperuricemic nephrocalcinosis, inflammatory bowel syndrome (type 1b), hypertriglyceridemia, and irregular menstrual cycles...
February 4, 2017: JIMD Reports
https://www.readbyqxmd.com/read/28155313/vitamin-d-status-hypertension-and-body-mass-index-in-an-urban-black-community-in-mangaung-south-africa
#9
Ronette Lategan, Violet L Van den Berg, Jasminka Z Ilich, Corinna M Walsh
BACKGROUND: A strong relationship exists between hypertension and body weight. Research has linked both higher blood pressure and body weight with lower vitamin D status. OBJECTIVE: This study assessed the vitamin D status of a low-income, urban, black community in South Africa, to examine whether serum levels of 25-hydroxy vitamin D [25(OH)D] are associated with hypertension and body mass index (BMI). METHODS: Data collected from 339 adults (25-64 years) from the Assuring Health for All in the Free State (AHA-FS) study were analysed...
October 31, 2016: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/28138903/the-treatment-of-giant-cell-arteritis
#10
REVIEW
Imran Jivraj, Madhura Tamhankar
Giant cell arteritis (GCA) is a systemic inflammatory vasculitis affecting medium and large vessels with potentially sight and life-threatening complications. Early diagnosis and prompt treatment are imperative in order to prevent vision loss and progression of the disease. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are inflammatory markers which are elevated in the majority of patients and support the diagnosis of GCA among patients who present with typical symptoms. GCA is confirmed with superficial temporal artery biopsy which demonstrates characteristic pathological findings...
January 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28120718/nutraceuticals-and-dietary-supplements-to-improve-quality-of-life-and-outcomes-in-heart-failure-patients
#11
Arrigo Fg Cicero, Alessandro Colletti
BACKGROUND: Heart failure (HF) is a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill or eject blood. It represents a major public health issue, with a prevalence of over 23 million worldwide. The lifetime risk of developing HF is one in five and the most important risk factors identified are ischemic heart disease, hypertension, smoking, obesity and diabetes. Preventive approaches are based on improvements of lifestyle, associated with pharmacological therapy...
January 24, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28077419/effect-of-vitamin-d-on-endothelial-function-a-randomized-double-blind-placebo-controlled-trial
#12
Lea Borgi, Ciaran McMullan, Ann Wohlhueter, Gary C Curhan, Naomi D Fisher, John P Forman
BACKGROUND: In nonhypertensive individuals, lower levels of 25-hydroxyvitamin D (25[OH]D) have been associated with an increased risk of hypertension, and vitamin D deficiency has been associated with endothelial dysfunction in such individuals. However, the effect of vitamin D supplementation on endothelial dysfunction in nonhypertensive individuals has not been examined in a rigorous fashion. METHODS: In this randomized, double-blind, placebo-controlled trial of nonhypertensive, nondiabetic overweight, or obese individuals with vitamin D deficiency (body mass index ≥25 and 25[OH]D ≤ 20 ng/ml), we assigned subjects to receive either ergocalciferol (50,000 units) or matching placebo, once a week for 8 weeks...
February 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28070240/newer-perspectives-of-coronary-artery-disease-in-young
#13
REVIEW
Amitesh Aggarwal, Saurabh Srivastava, M Velmurugan
Coronary artery disease (CAD) occurring in less than 45 years of age is termed as young CAD. Recent studies show a prevalence of 1.2% of CAD cases in this age group. Ethnic wise south Asians especially Indians are more vulnerable to have CAD in young age group with a prevalence of 5% to 10%. Conventional risk factors such as smoking, diabetes, hypertension, obesity and family history seems to be as important as in older CAD subjects. But the prevalence of these risk factors seems to vary in younger subjects...
December 26, 2016: World Journal of Cardiology
https://www.readbyqxmd.com/read/28068529/impact-of-high-dose-statins-on-vitamin-d-levels-and-platelet-function-in-patients-with-coronary-artery-disease
#14
Monica Verdoia, Patrizia Pergolini, Roberta Rolla, Matteo Nardin, Alon Schaffer, Lucia Barbieri, Veronica Daffara, Paolo Marino, Giorgio Bellomo, Harry Suryapranata, Giuseppe De Luca
BACKGROUND: Statins represent a pivotal treatment in coronary artery disease, offering a reduction in cardiovascular risk even beyond their lipid-lowering action. However, the mechanism of these "pleiotropic" benefits of statins is poorly understood. Vitamin D has been suggested as a potential mediator of the anti-inflammatory, anti-thrombotic and vascular protecting effects of statins. Aim of present study was to assess the impact of a high-intensity statin therapy on vitamin D levels and platelet function in patients with coronary artery disease...
February 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28045952/predictive-factors-of-one-year-mortality-in-a-cohort-of-patients-undergoing-urgent-start-hemodialysis
#15
Luciene P Magalhães, Luciene M Dos Reis, Fabiana G Graciolli, Benedito J Pereira, Rodrigo B de Oliveira, Altay A L de Souza, Rosa M Moyses, Rosilene M Elias, Vanda Jorgetti
BACKGROUND: Chronic kidney disease (CKD) affects 10-15% of adult population worldwide. Incident patients on hemodialysis, mainly those on urgent-start dialysis at the emergency room, have a high mortality risk, which may reflect the absence of nephrology care. A lack of data exists regarding the influence of baseline factors on the mortality of these patients. The aim of this study was to evaluate the clinical and laboratory characteristics of this population and identify risk factors that contribute to their mortality...
2017: PloS One
https://www.readbyqxmd.com/read/28045413/vitamin-d-levels-predict-the-response-to-cardiac-resynchronization-therapy-in-patients-with-systolic-heart-failure
#16
Hamza Sunman, Adem Özkan, Hikmet Yorgun, Uğur Canpolat, Naresh Maharjan, Serkan Asil, Ergün Barış Kaya, Tülin Bayrak, Lale Tokgözoğlu, Asuman Özkara, Kudret Aytemir, Ali Oto
OBJECTIVE: The aim of this study was to examine the relationship between vitamin D levels in patients with heart failure (HF) and response to cardiac resynchronization therapy (CRT). METHODS: We studied 57 patients (mean age: 60.47±13.09 years) with New York Heart Association Class II or III heart failure, QRS duration ?120 milliseconds, and ejection fraction <35% (mean: 27.1±4.4%) who underwent CRT. All patients were taking optimal medical treatment for HF...
December 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28043680/vitamin-d-and-cardiovascular-disease-from-atherosclerosis-to-myocardial-infarction-and-stroke
#17
REVIEW
Giovanna Muscogiuri, Cedric Annweiler, Guillaume Duval, Spyridon Karras, Giacomo Tirabassi, Gianmaria Salvio, Giancarlo Balercia, Samantha Kimball, Kalliopi Kotsa, Luca Mascitelli, Harjit Pal Bhattoa, Annamaria Colao
There continues to be interest in understanding the role of vitamin D in the pathogenesis, epidemiology and prevention of cardiovascular disease (CVD). In fact vitamin D deficiency has been associated to an increased risk of developing CVD given to the relationship between low vitamin D levels and obesity, diabetes mellitus, dyslipidaemia, endothelial dysfunction and hypertension. However, although vitamin D has been identified as a potentially important marker of CVD, the mechanisms through which vitamin D deficiency leads from endothelial dysfunction to myocardial infarction and stroke are not fully understood...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28040349/-effect-of-drugs-for-osteoporosis-on-cardiovascular-diseases-and-effect-of-cardio-vascular-drugs-on-osteoporosis
#18
Michel Laroche, Yannick Degboe, Hubert Blain, Véronique Breuil, Roland Chapurlat, Bernard Cortet, Bruno Sutter
Osteoporosis and cardiovascular diseases are epidemiologically associated. Calcification phenomena of atherosclerotic plaque involve cytokines and growth factors also involved in bone remodeling. Drugs given for either of these two conditions could act on these mechanisms. Can osteoporosis drugs have an influence on the occurrence of cardiovascular events? Conversely, can the treatment of hypertension alter the course of osteoporosis? It is possible that administration of high doses of calcium (1g/day) in patients who already have important dietary intake can increase the risk of myocardial infarction...
December 28, 2016: La Presse Médicale
https://www.readbyqxmd.com/read/28039036/nutritional-intake-depressive-symptoms-and-vitamin-d-status-in-hypertensive-patients-in-the-north-of-iran-a-case-control-study
#19
A Salari, M Mahdavi-Roshan, T Hasandokht, M Gholipour, S Soltanipour, M Nagshbandi, A Javadzadeh
OBJECTIVE: We investigated vitamin D status, body size, nutritional intake and depression status in hypertensive patients in the north of Iran that have special dietary habit and lifestyle according to their culture and geographical situation. MATERIALS AND METHODS: This study was conducted on 127 patients with newly recognized hypertension and the 120 normal participants, in the north of Iran. Anthropometric data was measured and demographic characteristics, dietary intake, depression and medical status were collected by valid questionnaires...
December 27, 2016: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/28033130/the-effect-of-vitamin-d-on-renin-angiotensin-system-activation-and-blood-pressure-a-randomized-control-trial
#20
Ciaran J McMullan, Lea Borgi, Gary C Curhan, Naomi Fisher, John P Forman
OBJECTIVE: Disruption of vitamin D signaling in rodents causes activation of the rennin-angiotensin system (RAS) and development of hypertension. Observational studies in humans found lower circulating 25-hydroxyvitamin D [25(OH)D] is associated with increased RAS activity and blood pressure (BP). We performed the first randomized control trial to investigate the effects of vitamin D supplementation on the RAS in humans. METHODS: Vitamin D deficient, [25(OH)D ≤20 ng/ml), overweight individuals without hypertension were randomized into a double-blind, placebo-controlled trial of 8-weeks treatment with ergocalciferol or placebo...
April 2017: Journal of Hypertension
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