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intraspinal delivery of bone marrow stromal cell derived neural stem cells

Shahriar Nafissi, Hadi Kazemi, Taki Tiraihi, Nahid Beladi-Moghadam, Soghrat Faghihzadeh, Elham Faghihzadeh, Davoud Yadegarynia, Mostafa Sadeghi, Leili Chamani-Tabriz, Abdollah Khanfakhraei, Taher Taheri
BACKGROUND: Stem cells have been used in several studies with different methodologies to treat patients with ALS. METHODS: In this safety and feasibility study, 11 patients with definite or probable ALS according to El Escorial criteria were selected. 3 patients were excluded due to inadequate bone marrow or safety measures after acquisition of bone marrow. Bone marrow stromal cell-derived neural stem cells were injected in C7-T1 spinal cord under general anesthesia...
March 15, 2016: Journal of the Neurological Sciences
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