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osteoporosis and exercise

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https://www.readbyqxmd.com/read/29767227/effect-of-a-balance-training-programme-on-postural-balance-aerobic-capacity-and-frequency-of-falls-in-women-with-osteoporosis-a-randomized-controlled-trial
#1
Ibolya Miko, Imre Szerb, Anna Szerb, Tamas Bender, Gyula Poor
OBJECTIVE: To investigate the effect of a 12-month complex balance-training programme on static and dynamic postural balance, aerobic capacity and frequency of falls in women with established osteoporosis. DESIGN: Randomized controlled trial in which the intervention group was assigned a 12-month exercise programme (3 times a week for 30 min) and the control group had no intervention. SUBJECTS: A total of 100 osteoporotic women with at least one previous fracture...
May 16, 2018: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29756977/effects-of-red-wine-grape-juice-and-resveratrol-consumption-on-bone-parameters-of-wistar-rats-submitted-to-high-fat-diet-and-physical-training
#2
Letícia Monteiro da Fonseca Cardoso, Nina Da Matta Alvarez Pimenta, Raiza Da Silva Ferreira Fiochi, Bruna Ferreira Mota Mota, Juliana Arruda de Souza Monnerat, Cristiane Correia Teixeira, Renata Beatriz Da Rocha Ramalho, Isabelle Waleska Maldronato, Manuela Dolisnky, Gilson Teles Boaventura, Vilma Blondet, Sergio Girão Barroso, Carlos Alberto Soares da Costa, Gabrielle De Souza Rocha
INTRODUCTION: intake of diets with high saturated fat may produce deleterious effects on bone mineralization. Lifestyle changes help reduce the bone loss observed in osteoporosis. Resveratrol, present in grape juice and red wine, has osteogenic and osteoinductive effects, being potentially beneficial for bone health. OBJECTIVE: to evaluate the effects of red grape juice, red wine and resveratrol consumption on bone parameters in Wistar rats submitted to a high-fat diet and physical training...
October 27, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29753373/dipstick-proteinuria-and-reduced-estimated-glomerular-filtration-rate-as-independent-risk-factors-for-osteoporosis
#3
Chun-Wu Tung, Yung-Chien Hsu, Ya-Hsueh Shih, Pey-Jium Chang, Chun-Liang Lin
BACKGROUND: Osteoporosis is associated with a poor quality of life and mortality. Proteinuria contributes to vitamin D deficiency and osteoblast dysfunction. The correlation between estimated glomerular filtration rate (eGFR) and bone density still remains elusive. Therefore, we sought to investigate whether reduced eGFR or proteinuria are independently associated with the osteoporotic risk. METHODS: We conducted a cross-sectional study using community-based health survey data from January 2004 to December 2008 in southern Taiwan...
May 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29738411/risk-factors-for-5-year-prospective-height-loss-among-postmenopausal-women
#4
Xiaodan Mai, Britt Marshall, Kathleen M Hovey, Jill Sperrazza, Jean Wactawski-Wende
OBJECTIVE: Height loss is common in older women and has been associated with increased morbidity and mortality. In this study, we identified factors that could predict prospective height loss in postmenopausal women. METHODS: Height was measured in 1,024 postmenopausal women, enrolled in the Buffalo Osteoporosis and Periodontal Disease Study, at baseline and 5 years later using a fixed stadiometer. Demographics, lifestyle, medical history, and medication use were assessed at baseline...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29737744/-clinical-analysis-of-adult-spontaneous-cerebrospinal-fluid-rhinorrhea
#5
Zheng Jie Zhu, Lan Cheng, Jun Yang, Qi Huang, Guo Zhen Meng, Rong Ping Cao
OBJECTIVES: To discuss the clinical characteristics, diagnosis and treatment of adult spontaneous cerebrospinal fluid rhinorrhea (CSFR). METHODS: A retrospective study was conducted on 18 patients of CSFR. Nasal secretion was collected for biochemical analysis. Imaging examination was done for identification of the bony defect in skull base. RESULTS: In all cases, the glucose concentration of nasal secretion were more than 1.7 mmol/L, and the β-2 transferrin detected by immunoelectrophoresis technique were positive...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29736771/increased-prevalence-of-asymptomatic-vertebral-fractures-in-hiv-infected-patients-over-50-years-of-age
#6
Maria Llop, W A Sifuentes, S Bañón, C Macia-Villa, M J Perez-Elías, M Rosillo, S Moreno, M Vázquez, J L Casado
The prevalence of asymptomatic vertebral fracture in HIV-infected patients over 50 was 20%, associated with older age, male sex, longer time since HIV diagnosis, and tubular renal alterations. Vertebral fractures were independent of osteoporosis at lumbar spine, and were not predicted by the use of the FRAX equation. PURPOSE: Vertebral fractures (VF) are the hallmark of osteoporotic fractures. Our objective was to determine the prevalence of asymptomatic VF and associated factors in HIV-infected patients over 50 years, and the role of FRAX equation...
May 8, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29727228/osteosarcopenia
#7
James Paintin, Cyrus Cooper, Elaine Dennison
Osteosarcopenia is a newly described syndrome that describes the co-existence of osteoporosis and sarcopenia, two chronic musculoskeletal conditions associated with ageing. Osteoporosis, a condition of low bone mass and micro-architectural deterioration of bone, and sarcopenia, the loss of muscle mass, strength and function, often co-exist in a frail subset of the elderly population, leading to significantly worsened outcomes than seen in either condition alone. These include a greater risk of falls, fractures and institutionalization, and significant socioeconomic costs...
May 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29714190/quantitative-study-of-the-influence-of-swimming-therapy-on-osteoporosis-rat-models-based-on-synchrotron-radiation-computed-tomogaphy
#8
Liya Huang, Jun Xu, Han Guo, Yujie Wang, Jun Zhao, Jianqi Sun
Osteoporosis is a bone disease with a variety of causes, leading to bone pain and fragility to fracture. Major treatment methods include nutrition therapy, exercise therapy, drug therapy and surgical treatment, among which exercise therapy, such as swimming, is the most effective. To investigate the optimal swimming therapy regime for postmenopausal women, the effects of eight weeks of different intensity swimming exercises were studied in rat models. After the swimming program, lumbar vertebrae were dissected from all the rats and scanned by synchrotron radiation computed tomography (SRCT)...
May 1, 2018: Journal of Synchrotron Radiation
https://www.readbyqxmd.com/read/29710770/exercise-early-and-often-effects-of-physical-activity-and-exercise-on-women-s-bone-health
#9
REVIEW
Karen L Troy, Megan E Mancuso, Tiffiny A Butler, Joshua E Johnson
In 2011 over 1.7 million people were hospitalized because of a fragility fracture, and direct costs associated with osteoporosis treatment exceeded 70 billion dollars in the United States. Failure to reach and maintain optimal peak bone mass during adulthood is a critical factor in determining fragility fracture risk later in life. Physical activity is a widely accessible, low cost, and highly modifiable contributor to bone health. Exercise is especially effective during adolescence, a time period when nearly 50% of peak adult bone mass is gained...
April 28, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29710141/interventions-to-prevent-falls-in-community-dwelling-older-adults-us-preventive-services-task-force-recommendation-statement
#10
David C Grossman, Susan J Curry, Douglas K Owens, Michael J Barry, Aaron B Caughey, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Martha Kubik, Seth Landefeld, Carol M Mangione, Michael Pignone, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: Falls are the leading cause of injury-related morbidity and mortality among older adults in the United States. In 2014, 28.7% of community-dwelling adults 65 years or older reported falling, resulting in 29 million falls (37.5% of which needed medical treatment or restricted activity for a day or longer) and an estimated 33 000 deaths in 2015. Objective: To update the 2012 US Preventive Services Task Force (USPSTF) recommendation on the prevention of falls in community-dwelling older adults...
April 24, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29705875/association-between-metabolic-syndrome-and-osteoporosis-in-taiwanese-middle-aged-and-elderly-participants
#11
Hsin-Hui Lin, Chun-Yuan Huang, Lee-Ching Hwang
This study examined the association between metabolic syndrome and osteoporosis among middle-aged and elderly Taiwanese participants. After controlling for body mass index, age, liver and renal functions, and nutrition and exercise statuses, we found no significant association between MS and osteoporosis in either gender. PURPOSE: The term metabolic syndrome (MS) encompasses different abnormalities with independent effects on bone metabolism, which has led to inconsistencies in the association between MS and osteoporosis...
April 28, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29705177/the-impact-of-exercise-and-vitamin-d-supplementation-on-physical-function-in-community-dwelling-elderly-individuals-a-randomized-trial
#12
Kana Aoki, Mayumi Sakuma, Naoto Endo
BACKGROUND: We investigated the impact of exercise and vitamin D supplementation on physical function and locomotor dysfunction in community-dwelling elderly individuals. METHODS: In total, 148 community-dwelling elderly individuals (aged ≥60 years) who were not taking osteoporosis medications participated in a 24-week intervention. The participants were randomly divided into an exercise group, vitamin D group, and exercise and vitamin D group. The participants and outcome-assessing staff were not blinded to group assignment...
April 25, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29704016/function-of-low-back-muscle-exercise-preventive-effect-of-refracture-analysis-of-postoperative-vertebral-fractures
#13
DeLi Deng, Zhen Lian, WenFei Cui, HeSheng Liang, LiJun Xiao, Guanfeng Yao
BACKGROUND: Low back muscles exercise reportedly influence the risk of osteoporotic vertebral fractures. The exact relationship between the low back muscles exercise and the incidence of vertebral refractures remain unclear. OBJECTIVE: To investigate the ability of exercise to strengthen the low back muscles to prevent vertebral refracture after surgery, through clinical analysis of the vertebral fracture risk reduction program. METHODS: In total 152 patients with vertebral fractures who had undergone percutaneous vertebroplasty (PVP) and anti-osteoporosis treatment were randomly divided into observation and control groups...
April 27, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29699580/genetic-deletion-of-muscle-rank-or-selective-inhibition-of-rankl-is-not-as-effective-as-full-length-opg-fc-in-mitigating-muscular-dystrophy
#14
Sébastien S Dufresne, Antoine Boulanger-Piette, Sabrina Bossé, Anteneh Argaw, Dounia Hamoudi, Laetitia Marcadet, Daniel Gamu, Val A Fajardo, Hideo Yagita, Josef M Penninger, A Russell Tupling, Jérôme Frenette
Although there is a strong association between osteoporosis and skeletal muscle atrophy/dysfunction, the functional relevance of a particular biological pathway that regulates synchronously bone and skeletal muscle physiopathology is still elusive. Receptor-activator of nuclear factor κB (RANK), its ligand RANKL and the soluble decoy receptor osteoprotegerin (OPG) are the key regulators of osteoclast differentiation and bone remodelling. We thus hypothesized that RANK/RANKL/OPG, which is a key pathway for bone regulation, is involved in Duchenne muscular dystrophy (DMD) physiopathology...
April 24, 2018: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/29687967/vertebral-compression-fractures-associated-with-yoga-a-case-series
#15
Jad G Sfeir, Matthew T Drake, Vikram J Sonawane, Mehrsheed Sinaki
BACKGROUND: The importance of exercise in skeletal health is increasingly recognized by both patients and providers. However, the safety of prescribed or recreational exercise in at-risk populations remains under-reported and under-publicized. Yoga has gained widespread popularity due to its physical and psychological benefits. When practiced in a population at increased fracture risk, however, some yoga poses may increase fracture risk, particularly at the spine, rather than increasing BMD as noted in recent popular press reports...
April 24, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29672438/alterations-of-inflammatory-and-matrix-production-indices-in-celiac-disease-with-low-bone-mass-on-long-term-gluten-free-diet
#16
Michele Di Stefano, Manuela Bergonzi, Irene Benedetti, Mara De Amici, Cristina Torre, Natascia Brondino, Emanuela Miceli, Elisabetta Pagani, Gian L Marseglia, Gino R Corazza, Antonio Di Sabatino
BACKGROUND: A clinically meaningful impairment of bone mass secondary to malabsorption is frequent in untreated celiac disease. In adult patients, a rigorous gluten-free diet (GFD) significantly improves, but does not always normalize, bone mineral density (BMD). The reason for this marginal response is unclear. Accordingly, we evaluated the role of both local and systemic factors for bone loss in celiac patients on long-term GFD. STUDY: In a prospective cohort, 22 patients with low lumbar and/or femoral BMD and 22 with normal BMD underwent bone and mineral metabolism evaluation: we tested calcium, phosphate, parathyroid hormone, and vitamin D; telopeptide of type I collagen, a bone resorption index; propeptide of type I procollagen, a bone neoformation index; receptor antagonist of NF-kB ligand, an osteoclast-stimulating factor; osteoprotegerin (OPG), a decoy receptor for RANKL...
April 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29662566/focal-increased-tc-99m-mdp-uptake-in-the-nutrient-foramen-of-the-femoral-diaphysis-on-bone-spect-ct
#17
Hwajin Cha, Soo Bin Park, Hyun-Joo Kim
We present images of an 83-year-old female with a history of osteoporosis and bilateral total knee replacement arthroplasty, referred for bone scintigraphy and single-photon emission computed tomography (SPECT)/computed tomography (CT), owing to left knee pain. No trauma to, or intense exercise of, the knee was reported. The bone scan and SPECT/CT revealed a focally increased Tc-99m methylene diphosphonate (MDP) uptake in the medial cortex of the left femoral diaphysis with matched linear radiolucency on CT images...
April 2018: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29619067/a-hop-extract-lifenol%C3%A2-improves-postmenopausal-overweight-osteoporosis-and-hot-flash-in-ovariectomized-rats
#18
Young-Hwan Ban, Jung-Min Yon, Yeseul Cha, Jieun Choi, Eun Suk An, Haiyu Guo, Da Woom Seo, Tae-Su Kim, Sung-Pyo Lee, Jong-Choon Kim, Ehn-Kyoung Choi, Yun-Bae Kim
Objective: In order to assess the effectiveness of a hop extract (HE) for postmenopausal symptoms, the effects of Lifenol on ovariectomy-induced osteoporosis, hyperlipidemia, body weight increase, and hot flash were investigated in rats. Methods: Female Sprague-Dawley rats were ovariectomized and subjected to a daily scheduled exercise training (15 min at 15 m/min) or treated with HE (30 or 100 mg/kg, oral) or 17 β -estradiol (100  μ g/kg, intraperitoneal) for 12 weeks...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29615028/effect-of-a-resistance-and-balance-exercise-programme-for-women-with-osteoporosis-and-vertebral-fracture-study-protocol-for-a-randomized-controlled-trial
#19
Brita Stanghelle, Hege Bentzen, Lora Giangregorio, Are Hugo Pripp, Astrid Bergland
BACKGROUND: Osteoporotic vertebral fractures are common, and are associated with reduced functioning and health related quality of life. The primary aims of this randomized controlled trial are to examine the immediate and long-term effects of a 12-weeks supervised group exercise programme on habitual walking speed in older women with osteoporosis and a history of vertebral fracture. The secondary aims are to examine the immediate and long-term effects of the exercise program on physical fitness, fear of falling and quality of life...
April 3, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29607594/management-of-the-female-athlete-triad
#20
Sayaka Nose-Ogura, Miyuki Harada, Osamu Hiraike, Yutaka Osuga, Tomoyuki Fujii
The female athlete triad (FAT) is defined by the American College of Sports Medicine (ACSM) as low energy availability (low EA), functional hypothalamic amenorrhoea and osteoporosis. In low EA, lutein dysfunction first develops, followed by anovulation and, subsequently, oligomenorrhea, leading to amenorrhea. Moreover, low estradiol concentrations due to amenorrhea decrease bone mineral density (BMD). In athletes with one of the factors of FAT, the risk of a stress fracture is 2.4-4.9 times higher and may increase the risk of fracture throughout the lifespan...
April 2, 2018: Journal of Obstetrics and Gynaecology Research
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