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https://www.readbyqxmd.com/read/28932313/serum-zinc-level-and-its-correlation-with-vesikari-system-scoring-in-acute-pediatric-diarrhea
#1
Ayman E Eskander, Lobna S Sherif, Mohammad Nabih, Nevine R El Baroudy, Ghobrial C Marcos, Ehsan A Badawy, Amira S El Refay
BACKGROUND: Diarrhea remains the most common infectious disease worldwide. Zinc has been studied extensively recently for its potential effect on prevention, control and treatment of acute diarrhoea. AIM: This study was designed to correlate the level of zinc with the severity of pediatric diarrhoea estimated by Vesikari Scoring System. PATIENTS AND METHODS: The present study included 80 children aged two months to 30 months from those suffering from the acute diarrheal episode and admitted to Pediatric Hospital "Abo El Rish" Cairo University...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28927157/selected-mirna-levels-are-associated-with-ikzf1-microdeletions-in-pediatric-acute-lymphoblastic-leukemia
#2
J Krzanowski, J Madzio, A Pastorczak, A Tracz, M Braun, J Tabarkiewicz, A Pluta, W Młynarski, I Zawlik
The clinical outcome of children with high-risk relapsed B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is poor. The present study assessed the utility and prognostic value of selected microRNA (miRNA/miR) in BCP-ALL. The changes in the expression levels of these miRNAs regarding known gene lesions affecting lymphoid development [early B-cell factor 1 (EBF1), ETS variant 6 (ETV6), IKAROS family zinc finger 1 (IKZF1), paired box 5 (PAX5), cyclin dependent kinase inhibitor (CDKN) 2A/CDKN2B, retinoblastoma 1 (RB1), pseudoautosomal region 1 (PAR1), B-cell translocation gene 1 protein (BTG1)] were analyzed...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28925036/combining-food-based-dietary-recommendations-using-optifood-with-zinc-fortified-water-potentially-improves-nutrient-adequacy-among-4-to-6-year-old-children-in-kisumu-west-district-kenya
#3
Prosper Kujinga, Karin J Borgonjen-van den Berg, Cecilia Superchi, Hermine J Ten Hove, Elizabeth Opiyo Onyango, Pauline Andang'o, Valeria Galetti, Michael B Zimmerman, Diego Moretti, Inge D Brouwer
Children in developing countries often face multiple micronutrient deficiencies. Introduction of zinc-fortified water can increase zinc intake, but additional recommendations are required to address overall diet nutrient adequacy. We developed and tested food-based recommendations (FBRs) that included zinc-fortified water for children aged between 4 and 6 years from rural Kenya to achieve the best possible nutrient adequacy. Dietary intakes of 60 children aged 4-6 years, from Kisumu West district, Kenya, were assessed using a quantitative multipass 24-hr recall...
September 19, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28924031/cytoplasmic-copper-detoxification-in-salmonella-can-contribute-to-sodc-metalation-but-is-dispensable-during-systemic-infection
#4
Luke A Fenlon, James M Slauch
Salmonella Typhimurium is a leading cause of foodborne disease worldwide. Severe infections result from the ability of S. Typhimurium to survive within host immune cells, despite being exposed to various host antimicrobial factors. SodCI, a copper-zinc cofactored superoxide dismutase, is required to defend against phagocytic superoxide. SodCII, an additional periplasmic superoxide dismutase, although produced during infection, does not function in the host. Previous studies suggested that CueP, a periplasmic copper binding protein, facilitates acquisition of copper by SodCII...
September 18, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28921450/nutrients-other-than-selenium-are-important-for-promoting-children-s-health-in-kashin-beck-disease-areas
#5
Yujie Ning, Xi Wang, Xiong Guo, Pan Zhang, Pengfei Qu, Feng Zhang, Sen Wang, Yanxia Lei, Mikko Lammi
Overall nutritional status has been proved associated with people's health. The overall nutritional status of children in Kashin-Beck disease (KBD) areas has been overlooked for decades. Therefore, it is worth investigating in the current generation to gather evidence and make suggestions for improvement. A cross-sectional study with three 24-h dietary recalls was conducted to collect raw data on the daily food intake of children. Recorded food was converted into daily nutrient intakes using CDGSS 3.0 software...
September 18, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28914251/clinical-and-radiographic-comparison-of-platelet-rich-fibrin-and-mineral-trioxide-aggregate-as-pulpotomy-agents-in-primary-molars
#6
Surendra Patidar, Namita Kalra, Amit Khatri, Rishi Tyagi
AIM: This study aimed to evaluate and compare the Platelet-rich fibrin (PRF) and Mineral trioxide aggregate (MTA) as a pulpotomy agent in primary molars. MATERIAL AND METHODS: In this study, 50 primary molars from 50 healthy children aged 5-9 years requiring pulpotomy were randomly allocated into two groups. In PRF group, after coronal pulp removal and hemostasis, remaining pulp tissue was covered with PRF preparation. In the MTA group, the pulp stumps were covered with MTA (Pro Root MTA-Root Canal Repair Material, Dentsply International Inc...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28914248/comparative-evaluation-of-clinical-and-radiological-success-of-zinc-oxide-ozonated-oil-modified-3mix-mp-antibiotic-paste-and-vitapex-as-treatment-options-in-primary-molars-requiring-pulpectomy-an-in-vivo-study
#7
Divya Doneria, Seema Thakur, Parul Singhal, Deepak Chauhan
OBJECTIVES: The aim of this study was to evaluate the clinical and radiographic success of zinc oxide-ozonated oil (ZnO-OO), modified 3Mix antibiotic paste, and Vitapex in treatment of primary molars requiring pulpectomy. METHODS: Sixty-four primary molars of forty three children aged between 4 and 8 years with pulpally involved primary molars requiring root canal procedures were treated with ZnO-OO, modified 3Mix-MP paste, and Vitapex. The subjects were followed up clinically at 1, 6, and 12 months whereas radiographically at 6 and 12 months, respectively...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28899425/the-physiological-determinants-of-low-level-urine-cadmium-an-assessment-in-a-cross-sectional-study-among-schoolchildren
#8
Hongyu Wang, Xavier Dumont, Vincent Haufroid, Alfred Bernard
BACKGROUND: Recent studies in children have reported associations of urinary cadmium (U-Cd), used as biomarker of Cd body burden, with renal dysfunction, retarded growth and impaired cognitive development in children. Little is known, however, about factors influencing U-Cd in children and likely to act as confounders. METHODS: In a cross-sectional study involving 249 schoolchildren (mean age, 5.72 years; 138 boys), we measured the urine concentrations of cadmium, zinc, lead, albumin, alpha1-microglobulin (A1M), retinol-binding protein, β2-microglobulin and club cell protein (CC16)...
September 12, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28894702/effects-of-hair-metals-on-body-weight-in-iranian-children-aged-20-to-36-months
#9
Mohsen Vigeh, Kazuhito Yokoyama, Takehisa Matsukawa, Atsuko Shinohara, Mamak Shariat, Katsumi Ohtani
BACKGROUND: Although the level of exposure to many toxic metals decreased recently, the adverse effects of these metals on children's growth and development remain a serious public health issue. METHODS: The present study was conducted in three teaching hospitals affiliated with Tehran University of Medical Sciences (Tehran, Iran) from Sep 2012 to Mar 2013. To study the relationship between metals and childhood growth, concentrations of zinc and several potentially toxic metals (lead, cadmium, antimony, cobalt, and molybdenum) were measured in scalp hair for 174 children, aged 20 to 36 months...
August 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28883729/maternal-exposure-to-nanosized-titanium-dioxide-suppresses-embryonic-development-in-mice
#10
Fashui Hong, Yingjun Zhou, Xiaoyang Zhao, Lei Sheng, Ling Wang
Although nanoscale titanium dioxide (nano-TiO2) has been extensively used in industrial food applications and daily products for pregnant women, infants, and children, its potential toxicity on fetal development has been rarely studied. The main objective of this investigation was to establish the effects of maternal exposure of nano-TiO2 on developing embryos. Female imprinting control region mice were orally administered nano-TiO2 from gestational day 0 to 17. Our findings showed that Ti concentrations in maternal serum, placenta, and fetus were increased in nano-TiO2-exposed mice when compared to controls, which resulted in reductions in the contents of calcium and zinc in maternal serum, placenta, and fetus, maternal weight gain, placental weight, fetal weight, number of live fetuses, and fetal crown-rump length as well as cauda length, and caused an increase in the number of both dead fetuses and resorptions...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28861860/interaction-of-lead-with-calcium-iron-and-zinc-in-the-biological-samples-of-malnourished-children
#11
Sehrish Talpur, Hassan I Afridi, Tasneem G Kazi, Farah Naz Talpur
Interaction between toxic and essential elements is of particular interest, because the deficiency of essential element can dramatically increase the absorption rate of toxic metals inside the body. This study was conducted to evaluate the possible correlation of lead (Pb) with calcium (Ca), iron (Fe), and zinc (Zn) in biological samples (whole blood and scalp hair) of malnourished children (MNC). For comparative purposes, age-matched, well-nourished children (WNC) were selected. The concentrations of understudy elements were analyzed by atomic absorption spectrophotometry after microwave acid digestion...
August 31, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28861723/health-risk-assessment-of-heavy-metal-variability-in-sachet-water-sold-in-ado-odo-ota-south-western-nigeria
#12
PraiseGod Chidozie Emenike, Theophilus Imokhai Tenebe, Maxwell Omeje, Damilare Samuel Osinubi
The sales of sachet water (SW), also known as "pure water" (PW), in Nigeria is a lucrative business. It serves many people, especially low-income earners, by providing a more affordable access to safe drinking water when compared with table water. However, some of the producers of SW do not effectively treat raw water before packaging them for sale. This study investigates the presence and concentrations of heavy metals, such as chromium (Cr), iron (Fe), manganese (Mn), copper (Cu), aluminum (Al), and zinc (Zn) in some samples of SW sold within Ota, Ogun State, Nigeria...
August 31, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28854208/delaying-the-start-of-iron-until-28-days-after-antimalarial-treatment-is-associated-with-lower-incidence-of-subsequent-illness-in-children-with-malaria-and-iron-deficiency
#13
Ericka G Jaramillo, Ezekiel Mupere, Robert O Opoka, James S Hodges, Troy C Lund, Michael K Georgieff, Chandy C John, Sarah E Cusick
We evaluated the incidence of all-cause and malaria-specific clinic visits during follow-up of a recent trial of iron therapy. In the main trial, Ugandan children 6-59 months with smear-confirmed malaria and iron deficiency [zinc protoporphyrin (ZPP > = 80 μmol/mol heme)] were treated for malaria and randomized to start a 27-day course of oral iron concurrently with (immediate group) or 28 days after (delayed group) antimalarial treatment. All children were followed for the same 56-day period starting at the time of antimalarial treatment (Day 0) and underwent passive and active surveillance for malaria and other morbidity for the entire follow-up period...
2017: PloS One
https://www.readbyqxmd.com/read/28841170/contaminations-sources-and-health-risks-of-trace-metal-loid-s-in-street-dust-of-a-small-city-impacted-by-artisanal-zn-smelting-activities
#14
Tingting Wu, Xiangyang Bi, Zhonggen Li, Guangyi Sun, Xinbin Feng, Lihai Shang, Hua Zhang, Tianrong He, Ji Chen
To investigate the impact of artisanal zinc smelting activities (AZSA) on the distribution and enrichment of trace metal(loid)s in street dust of a small city in Guizhou province, SW China, street dust samples were collected and analyzed for 10 trace metal(loid)s (Cr, Co, Ni, Cu, Zn, As, Cd, Sb, Pb, and Hg). Meanwhile, the health risks of local resident exposed to street dust were assessed. The result showed that the average concentrations of 10 elements were Zn (1039 mg kg(-1)), Pb (423 mg kg(-1)), Cr (119 mg kg(-1)), Cu (99 mg kg(-1)), As (55 mg kg(-1)), Ni (39 mg kg(-1)), Co (18 mg kg(-1)), Sb (7...
August 25, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28832571/the-effect-of-inflammation-on-serum-zinc-concentrations-and-the-prevalence-estimates-of-population-level-zinc-status-among-congolese-children-aged-6-59-months
#15
C D Karakochuk, S I Barr, E Boy, E Bahizire, P L Tugirimana, P Z Akilimali, L A Houghton, T J Green
BACKGROUND/OBJECTIVES: Zinc is a negative acute-phase reactant; hence, its concentration decreases in the presence of inflammation. There is no current consensus on how to control for the effect of inflammation on serum zinc, which has implications for accurate estimates of population-level zinc status. We aimed to measure the association between inflammation and serum zinc concentrations and to compare the means and the prevalence of zinc deficiency using unadjusted and inflammation-adjusted serum zinc concentrations among Congolese children...
August 23, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28822338/in-vitro-bioaccessibility-and-health-risk-assessment-of-heavy-metals-in-atmospheric-particulate-matters-from-three-different-functional-areas-of-shanghai-china
#16
Huang Huang, Ying Jiang, Xiaoyun Xu, Xinde Cao
The bioaccessibility and human health risks of heavy metals in PM2.5 and PM10 samples from three functional areas of Shanghai, China including a commercial area (CA), a residential area (RA), and an industrial area (IA), were investigated. Gamble's solution and physiologically based extraction test were employed to simulate human respiratory and digestive system, respectively. Both PM2.5 and PM10 concentration in the three areas exceeded the guideline of WHO, and followed the order of IA>CA≈RA. Zinc and Pb were the most abundant metals with a concentration range of 0...
August 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28805771/-synergistic-application-of-zinc-and-vitamin-c-to-support-memory-attention-and-the-reduction-of-the-risk-of-the-neurological-diseases
#17
O A Gromova, I Yu Torshin, A V Pronin, M A Kilchevsky
Zinc and vitamin C supplementation of the body is important for CNS functioning. Zinc ions are involved in the neurotransmission (signal transmission from acetylcholine, catecholamine, serotonin, prostaglandin receptors) and in ubiquitin-related protein degradation. Zinc deficits are associated with Alzheimer's disease and depression. Zinc supplementation (10-30 mg daily) improves neurologic recovery rate in patients with stroke and brain injury, has a positive impact on memory and reduces hyperactivity in children...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28799141/trace-element-and-vitamin-concentrations-in-paediatric-dialysis-patients
#18
Triona Joyce, Frances Court Brown, Dean Wallace, Christopher J D Reid, Manish D Sinha
BACKGROUND: There are few recent data regarding blood micronutrient concentrations and supplementation in children on maintenance dialysis. We investigated micronutrient concentrations following dialysis commencement. METHODS: Retrospective review, including all children on maintenance dialysis (peritoneal dialysis, PD; intermittent haemodialysis, IHD), for nutritional blood concentrations measured over the first 12 months. Patients received pyridoxine and Dialyvit® daily with planned 3-monthly micronutrient concentration monitoring including selenium, manganese, copper, zinc, folate and vitamins A, D, B12 and E...
August 10, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28783109/health-risks-and-contamination-levels-of-heavy-metals-in-dusts-from-parks-and-squares-of-an-industrial-city-in-semi-arid-area-of-china
#19
Xiufeng Han, Xinwei Lu, Yongfu Wu
The contamination characteristics and health risk of barium (Ba), cobalt (Co), chromium (Cr), copper (Cu), manganese (Mn), nickel (Ni), lead (Pb), vanadium (V), zinc (Zn), arsenic (As), mercury (Hg), and cadmium (Cd) in samples of dust gathered from squares and parks of Baotou city, an industrial city situated in a semi-arid location of the northwest China were investigated. The contents of Ba, Co, Cr, Cu, Mn, Ni, V, Pb, and Zn in the collected dust samples were determined using X-ray fluorescence spectrometry, while the contents of As and Hg in the dust were investigated by use of the ICP-MS...
August 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28780718/clinical-and-radiographic-comparison-of-biodentine-mineral-trioxide-aggregate-and-formocresol-as-pulpotomy-agents-in-primary-molars
#20
P Juneja, S Kulkarni
AIM: To compare the clinical and radiographic success rates of three different pulpotomy agents in primary molars after 18 months. METHODS: The study was carried out with 51 primary molars of children aged 5-9 years old. The teeth were randomly assigned to the experimental or control groups. After coronal pulp removal and haemostasis, the remaining pulp tissue was covered with Biodentine(®) or mineral trioxide aggregate in the experimental groups. In the control group, formocresol was placed with a cotton pellet over the pulp tissue for 5 min and after removal the pulp tissue was covered with zinc oxide-eugenol (ZOE) paste...
August 5, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
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