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Keywords predictors of Pseudomonas and ...

predictors of Pseudomonas and staphylococcus

https://read.qxmd.com/read/38482328/risk-factors-and-etiology-of-early-onset-neonatal-sepsis-in-northeastern-part-of-india-case-control-study
#1
JOURNAL ARTICLE
Sudesh Kumar, Piyali Bhattacharya, Simranjit Kaur, Prajna Ray, Nandita Chattopadhyay
BACKGROUND: Sepsis, the second most common cause of neonatal mortality, causes more than one million deaths annually. India has the highest incidence of clinical sepsis (17000/100000 live birth). OBJECTIVE: This study aimed to determine the risk factors and organisms of early-onset neonatal sepsis (EONS) in a tertiary care hospital in Northeast India. MATERIALS AND METHODS: It was a case-control study conducted in the neonatal unit of MGM Medical College, Kishanganj, Bihar, from January 2022 to April 2023...
January 2024: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/38166702/hospitalization-case-fatality-comorbidities-and-isolated-pathogens-of-adult-inpatients-with-pneumonia-from-2013-to-2022-a-real-world-study-in-guangzhou-china
#2
JOURNAL ARTICLE
Yun Li, Zhufeng Wang, Lunfang Tan, Lina Liang, Shuyi Liu, Jinhai Huang, Junfeng Lin, Kang Peng, Zihui Wang, Qiasheng Li, Wenhua Jian, Baosong Xie, Yi Gao, Jinping Zheng
BACKGROUND: In the context of increasing population aging, ongoing drug-resistant pathogens and the COVID-19 epidemic, the changes in the epidemiological and clinical characteristics of patients with pneumonia remain unclear. This study aimed to assess the trends in hospitalization, case fatality, comorbidities, and isolated pathogens of pneumonia-related adult inpatients in Guangzhou during the last decade. METHODS: We retrospectively enrolled hospitalized adults who had doctor-diagnosed pneumonia in the First Affiliated Hospital of Guangzhou Medical University from January 1, 2013 to December 31, 2022...
January 2, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38125533/predictors-of-hospital-mortality-and-multidrug-resistant-pathogens-in-hospitalized-pneumonia-patients-residing-in-the-community
#3
JOURNAL ARTICLE
Tomohiko Ukai, Takaya Maruyama, Shinichi Tomioka, Takumi Fukui, Shinya Matsuda, Kiyohide Fushimi, Hiroyasu Iso
BACKGROUND AND OBJECTIVE: The 2019 ATS/ADSA guidelines for adult community-acquired pneumonia (CAP) eliminated healthcare-associated pneumonia (HCAP) and considered it to be a form of CAP. This concept, however, was based on studies with relatively small sample sizes. METHODS: We investigated the risk factors of 30-day mortality, and methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa infections in patients with pneumonia coming from the community using the Diagnosis Procedure Combination database, a nationwide discharge database of acute care hospitals...
December 2023: Heliyon
https://read.qxmd.com/read/37927447/methicillin-resistant-staphylococcus-aureus-and-pseudomonas-aeruginosa-community-acquired-pneumonia-prevalence-and-locally-derived-risk-factors-in-a-single-hospital-system
#4
JOURNAL ARTICLE
Bradley W Frazee, Amarinder Singh, Matt Labreche, Partow Imani, Kevin Ha, Jonathan Furszyfer Del Rio, Eugene Kreys, Robert Mccabe
OBJECTIVES: Current American Thoracic Society/Infectious Disease Society of America (ATS/IDSA) community-acquired pneumonia (CAP) guidelines expand the CAP definition to include infections occurring in patients with recent health care exposure. The guidelines now recommend that hospital systems determine their own local prevalence and predictors of Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA) among patients satisfying this new broader CAP definition. We sought to carry out these recommendations in our system, focusing on the emergency department, where CAP diagnosis and initial empiric antibiotic selection usually ooccur...
December 2023: Journal of the American College of Emergency Physicians open
https://read.qxmd.com/read/37776130/epidemiological-features-antimicrobial-resistance-profile-and-clinical-outcomes-of-healthcare-associated-infections-in-islamic-republic-of-iran
#5
JOURNAL ARTICLE
Shahnaz Rimaz, Parastoo Tajzadeh, Milad Bahrami, Mehdi Nooghabi, Babak Eshrati, Sohrab Effati, Maryam Yaghoobi
BACKGROUND: Healthcare-associated infections are a major cause of mortality worldwide, especially in intensive care units where severely ill patients have limited physical space. AIMS: To investigate the incidence, microbial aetiology, antimicrobial resistance profile, and mortality rate of healthcare-associated infections in intensive care units in the Islamic Republic of Iran. METHODS: This observational study retrospectively reviewed the medical records of 1722 intensive care units patients with confirmed healthcare-associated infections at hospitals affiliated with Mashhad University of Medical Sciences in 2017-2019...
September 9, 2023: Eastern Mediterranean Health Journal
https://read.qxmd.com/read/37707656/phenotypic-and-genotypic-characterizations-of-bacteria-isolated-from-the-respiratory-microbiota-of-healthy-turkeys-with-potential-for-probiotic-composition
#6
JOURNAL ARTICLE
Michele Trintinaglia, Kelly Cristina Tagliari de Brito, Renata Katsuko Takayama Kobayashi, Luciana Kazue Otutumi, Gerson Nakazato, Luís Eduardo de Souza Gazal, Victor Dellevedove Cruz, Benito Guimarães de Brito
Desirable characteristics of Staphylococcus sp., Streptococcus sp., Bacillus sp., Klebsiella sp., Escherichia coli, and Pseudomonas pseudoalcaligenes isolated from the trachea of healthy turkeys were evaluated as probiotic candidates in the search for new alternatives to solve antimicrobial resistance issues in poultry. In current study phenotypic and genotypic capacity to produce bacteriocin-like substances, efficacy to inhibit the growth of avian pathogens, susceptibility to antimicrobials of bacteria isolated from the respiratory microbiota of healthy turkeys, and the presence of virulence-associated genes (VAGs) predictors of Avian Pathogenic Escherichia coli (APEC) were evaluated...
September 14, 2023: Veterinary Research Communications
https://read.qxmd.com/read/37317184/relative-abundance-and-detection-of-pseudomonas-aeruginosa-from-chronic-wound-infections-globally
#7
REVIEW
Sang Phan, Cafrey He Feng, Raymond Huang, Zeng X Lee, Yer Moua, Olivia J Phung, Justin R Lenhard
Pseudomonas aeruginosa is a difficult-to-treat pathogen that is frequently involved with chronic wound infections. Here, we conducted a literature search of world-wide studies published between 2005 and 2022 that described the microbiological profiles of chronic wound infections. For each continent, a hierarchy of pathogens was created to define the organisms that were most frequently isolated in each region. Except for South America, P. aeruginosa was the second most common organism in each major continent, with Staphylococcus aureus being the most abundant pathogen overall...
May 5, 2023: Microorganisms
https://read.qxmd.com/read/37252470/ventilator-associated-pneumonia-in-paediatric-intensive-care-unit-patients-microbiological-profile-risk-factors-and-outcome
#8
JOURNAL ARTICLE
Piyali Bhattacharya, Arvind Kumar, Sanat Kumar Ghosh, Sudesh Kumar
Introduction Ventilator-associated pneumonia (VAP) is one of the dreaded events in sick children who are ventilated in the paediatric intensive care unit (PICU) and has a high mortality rate. So, there is a need to know the causative organisms, risk factors, and possible predictors in a particular PICU for prevention, early identification, and treatment to decrease morbidity and mortality. This study was planned with the objectives to determine the microbiological profile, associated risk factors, and outcome of VAP in children...
April 2023: Curēus
https://read.qxmd.com/read/36977789/prediction-of-ciprofloxacin-resistance-in-hospitalized-patients-using-machine-learning
#9
JOURNAL ARTICLE
Igor Mintz, Michal Chowers, Uri Obolski
BACKGROUND: Ciprofloxacin is a widely used antibiotic that has lost efficiency due to extensive resistance. We developed machine learning (ML) models that predict the probability of ciprofloxacin resistance in hospitalized patients. METHODS: Data were collected from electronic records of hospitalized patients with positive bacterial cultures, during 2016-2019. Susceptibility results to ciprofloxacin (n = 10,053 cultures) were obtained for Escherichia coli, Klebsiella pneumoniae, Morganella morganii, Pseudomonas aeruginosa, Proteus mirabilis and Staphylococcus aureus...
March 28, 2023: Commun Med (Lond)
https://read.qxmd.com/read/36861046/determinants-of-mortality-for-ventilated-hospital-acquired-pneumonia-and-ventilator-associated-pneumonia
#10
JOURNAL ARTICLE
Hayley Motowski, Daniel Ilges, Nicholas Hampton, Marin H Kollef, Scott T Micek
UNLABELLED: Hospital-acquired pneumonia (HAP) is the most common hospital-acquired infection, accounting for 22% of all nosocomial infections. The available studies to date have not attempted to assess whether confounding factors may account for the observed difference in mortality for the two forms of nosocomial pneumonia associated with mechanical ventilation, namely ventilated HAP (vHAP) and ventilator-associated pneumonia (VAP). OBJECTIVES: To determine if vHAP is an independent predictor of mortality among patients with nosocomial pneumonia...
March 2023: Critical care explorations
https://read.qxmd.com/read/36700572/prevalence-outcomes-and-predictors-of-multidrug-resistant-nosocomial-lower-respiratory-tract-infections-among-patients-in-an-icu
#11
JOURNAL ARTICLE
Ana Beatriz Souza de Oliveira, Guilherme Hirassawa Sacillotto, Manuela Francisco Balthazar Neves, Andressa Hellen Nora da Silva, Tamiris Adriane Moimaz, Joelma Villafanha Gandolfi, Mara Correa Lelles Nogueira, Suzana Margareth Lobo
OBJECTIVE: To determine the prevalence, outcomes, and predictors of multidrug-resistant nosocomial lower respiratory tract infections (LRTI) in patients in an ICU. METHODS: This was an observational cohort study involving patients with nosocomial LRTI (health care-associated pneumonia, hospital-acquired pneumonia, or ventilator-associated pneumonia). Data were prospectively collected between 2015 and 2019. The multidrug-resistant pathogens (MDRPs) identified in the isolates studied included resistant to extended-spectrum cephalosporin-resistant and carbapenem-resistant Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa, carbapenem-resistant Enterobacteriaceae, and methicillin-resistant Staphylococcus aureus at microbiological diagnosis...
2023: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/36551465/the-antimicrobial-resistance-amr-rates-of-uropathogens-in-a-rural-western-african-area-a-retrospective-single-center-study-from-kpando-ghana
#12
JOURNAL ARTICLE
Susanne Deininger, Therese Gründler, Sebastian Hubertus Markus Deininger, Karina Lütcke, Harry Lütcke, James Agbesi, Williams Ladzaka, Eric Gyamfi, Florian Wichlas, Valeska Hofmann, Eva Erne, Peter Törzsök, Lukas Lusuardi, Jan Marco Kern, Christian Deininger
Little is known about the antimicrobial resistance (AMR) status of uropathogens in Western Africa. We performed a retrospective evaluation of urine cultures collected from the rural Margret Marquart Catholic Hospital, Kpando, Ghana during the time period from October 2019-December 2021. Urine samples from 348 patients (median age 40 years, 52.6% male) were examined. Of these, 125 (35.9%) showed either fungal or bacterial growth, including Escherichia coli in 48 (38.4%), Candida species (spp.) in 29 (23.2%), Klebsiella spp...
December 13, 2022: Antibiotics
https://read.qxmd.com/read/36536455/risk-factors-for-colonization-by-carbapenemase-producing-bacteria-in-spanish-long-term-care-facilities-a-multicentre-point-prevalence-study
#13
MULTICENTER STUDY
Manuel Callejón Fernández, Ana Madueño Alonso, Rossana Abreu Rodríguez, Armando Aguirre-Jaime, María Beatriz Castro Hernández, María José Ramos-Real, Yanet Pedroso-Fernández, María Lecuona Fernández
BACKGROUND: The emergence of carbapenemase-producing bacteria (CPB) has become a major public health concern. Long-term care facilities (LTCF) are potential reservoirs for multidrug-resistant micro-organisms (MDRO). However, data on CPB is limited. The study aims to determine the prevalence of MDRO and risk factors for CPB colonization among residents of LTCFs. METHODS: A point-prevalence study was conducted at 14 LTCFs in Tenerife (Spain) between October 2020 and May 2021...
December 20, 2022: Antimicrobial Resistance and Infection Control
https://read.qxmd.com/read/36415193/-value-of-procalcitonin-in-the-diagnosis-of-perioperative-infection-in-patients-undergoing-primary-hip-replacement
#14
JOURNAL ARTICLE
Shan-Zheng Zhang, Zhi-Jun Luo, Ling Ye
OBJECTIVE: To analyze the value of procalcitonin (PCT) in the diagnosis of perioperative infection associated with implants in patients with primary hip arthroplasty. METHODS: A retrospective study was conducted on 150 patients who underwent primary hip arthroplasty from June 2018 to June 2020, including 86 males and 64 females, aged from 47 to 77 years old with an average of (57.04±7.43) years. All patients with primary hip arthroplasty were divided into infection group and non infection group according to whether there was infection after operation...
November 25, 2022: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://read.qxmd.com/read/36402792/gut-microbiota-analysis-for-prediction-of-clinical-relapse-in-crohn-s-disease
#15
JOURNAL ARTICLE
Sylvie Buffet-Bataillon, Guillaume Bouguen, François Fleury, Vincent Cattoir, Yann Le Cunff
The role of intestinal bacterial microbiota has been described as key in the pathophysiology of Crohn's disease (CD). CD is characterized by frequent relapses after periods of remission which are not entirely understood. In this paper, we investigate whether the heterogeneity in microbiota profiles in CD patients could be a suitable predictor for these relapses. This prospective observational study involved 259 CD patients, in which 41 provided an additional total of 62 consecutive fecal samples, with an average interval of 25 weeks in between each of these samples...
November 19, 2022: Scientific Reports
https://read.qxmd.com/read/36358232/trends-in-the-bacterial-prevalence-and-antibiotic-resistance-patterns-in-the-acute-exacerbation-of-chronic-obstructive-pulmonary-disease-in-hospitalized-patients-in-south-india
#16
JOURNAL ARTICLE
Mohammed Kaleem Ullah, Sowmya Malamardi, Jayaraj Biligere Siddaiah, Tejashree A, Akila Prashant, Prashant Vishwanath, Lee W Riley, Purnima Madhivanan, Padukudru Anand Mahesh
Exacerbation due to antimicrobial-drug-resistant bacteria among chronic obstructive pulmonary disease (AECOPD) patients contributes to mortality and morbidity. We examined the prevalence of the bacterial organisms and trends in drug resistance in AECOPD. In this retrospective study, between January 2016 to December 2020, among 3027 AECOPD patients, 432 (14.3%) had bacteria isolated. The regression and generalized estimating equations (GEE) were used for trends in the resistance patterns over five years, adjusting for age, gender, and comorbidities...
November 9, 2022: Antibiotics
https://read.qxmd.com/read/35963814/predicting-risk-adjusted-incidence-rates-of-methicillin-resistant-staphylococcus-aureus-and-pseudomonas-aeruginosa-in-cystic-fibrosis-programs-in-the-united-states
#17
JOURNAL ARTICLE
William Stoudemire, Xiaotong Jiang, Juyan J Zhou, Michael R Kosorok, Lisa Saiman, Marianne S Muhlebach
BACKGROUND: Healthcare-associated transmission of methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa occurs for people with cystic fibrosis (CF), but CF programs lack a process to monitor incidence rates (IRs). We assessed predictors of incident infections and created a model to determine risk-adjusted IRs for CF programs. METHODS: Using the CF Foundation Patient Registry data for all patients from 2012 to 2015, coefficients for variables that predicted IRs were estimated...
August 10, 2022: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://read.qxmd.com/read/35956807/biofilm-i-a-platform-for-predicting-biofilm-inhibitors-using-quantitative-structure-relationship-qsar-based-regression-models-to-curb-antibiotic-resistance
#18
JOURNAL ARTICLE
Akanksha Rajput, Kailash T Bhamare, Anamika Thakur, Manoj Kumar
Antibiotic drug resistance has emerged as a major public health threat globally. One of the leading causes of drug resistance is the colonization of microorganisms in biofilm mode. Hence, there is an urgent need to design novel and highly effective biofilm inhibitors that can work either synergistically with antibiotics or individually. Therefore, we have developed a recursive regression-based platform "Biofilm- i " employing a quantitative structure-activity relationship approach for making generalized predictions, along with group and species-specific predictions of biofilm inhibition efficiency of chemical(s)...
July 29, 2022: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/35911104/antibacterial-and-biofilm-degradation-effects-of-hungarian-honeys-linked-with-botanical-origin-antioxidant-capacity-and-mineral-content
#19
JOURNAL ARTICLE
Ágnes Farkas, Viktória Lilla Balázs, Tamás Kõszegi, Rita Csepregi, Erika Kerekes, Györgyi Horváth, Péter Szabó, Krisztián Gaál, Marianna Kocsis
The aim of the study was to assess the impact of four unifloral honeys on the food-borne pathogens Pseudomonas aeruginosa and Staphylococcus aureus , by analyzing the honeys' antibacterial and biofilm degradation effects, as well as their antioxidant activity and element content. Linden and milkweed honeys represented light colored honeys, while goldenrod and chestnut honeys the darker ones. The botanical origin of the honeys and the relative frequency of their pollen types were established with melissopalynological analysis...
2022: Frontiers in Nutrition
https://read.qxmd.com/read/35873292/prevalence-and-predictors-of-pseudomonas-aeruginosa-among-hospitalized-patients-with-diabetic-foot-infections
#20
JOURNAL ARTICLE
Michael P Veve, Nicholas J Mercuro, Ryan J Sangiovanni, Maressa Santarossa, Nimish Patel
Background: Diabetic foot infections (DFIs) are commonly associated with antibiotic overuse. Empiric DFI treatment often includes coverage for Pseudomonas aeruginosa (PsA), but the frequency of PsA DFIs is poorly understood. The study objectives were to quantify the prevalence of and determine predictors for PsA DFIs. Methods: This multicenter, retrospective cohort included hospitalized patients with DFI from 2013 through 2020 who were age ≥18 years; diabetes mellitus diagnosis; and DFI based on International Classification of Diseases, Tenth Revision coding, antibiotic treatment, and DFI culture with organism growth...
July 2022: Open Forum Infectious Diseases
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