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Catheter-Related Infection

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https://www.readbyqxmd.com/read/29452598/7-versus-14-days-of-antibiotic-treatment-for-critically-ill-patients-with-bloodstream-infection-a-pilot-randomized-clinical-trial
#1
Nick Daneman, Asgar H Rishu, Ruxandra Pinto, Pierre Aslanian, Sean M Bagshaw, Alex Carignan, Emmanuel Charbonney, Bryan Coburn, Deborah J Cook, Michael E Detsky, Peter Dodek, Richard Hall, Anand Kumar, Francois Lamontagne, Francois Lauzier, John C Marshall, Claudio M Martin, Lauralyn McIntyre, John Muscedere, Steven Reynolds, Wendy Sligl, Henry T Stelfox, M Elizabeth Wilcox, Robert A Fowler
BACKGROUND: Shorter-duration antibiotic treatment is sufficient for a range of bacterial infections, but has not been adequately studied for bloodstream infections. Our systematic review, survey, and observational study indicated equipoise for a trial of 7 versus 14 days of antibiotic treatment for bloodstream infections; a pilot randomized clinical trial (RCT) was a necessary next step to assess feasibility of a larger trial. METHODS: We conducted an open, pilot RCT of antibiotic treatment duration among critically ill patients with bloodstream infection across 11 intensive care units (ICUs)...
February 17, 2018: Trials
https://www.readbyqxmd.com/read/29446842/epidemiology-and-risk-factors-for-outpatient-acquired-catheter-related-bloodstream-infections-in-children-receiving-home-parenteral-nutrition
#2
Laura J Wozniak, Hannah M Bechtold, Laurie E Reyen, Alvin P Chan, Elizabeth A Marcus, Jorge H Vargas
BACKGROUND: Few studies have examined the epidemiology and risk factors for the development of outpatient-acquired catheter-related bloodstream infections (CRBSIs) in children receiving home parenteral nutrition. This study aimed to (1) characterize the incidence, clinical presentation, and epidemiology of CRBSIs and (2) identify risk factors for CRBSIs in children receiving home parenteral nutrition. METHODS: A longitudinal database approved by our Institutional Review Board was created to prospectively track CRBSIs in the UCLA pediatric population from January to December 2012...
February 15, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29443407/implanted-vascular-access-device-options-a-focused-review-on-safety-and-outcomes
#3
REVIEW
Merilda O Blanco-Guzman
Implantable vascular access devices are frequently used in patients who have poor peripheral venous access. These devices can be partially implanted as tunneled and nontunneled central catheters, or they can be fully implanted as ports. Compared with long-term catheters, implanted ports have lower infection rates and improved perceptions of quality of life, but complications still occur in 2% to 18% of patients, frequently requiring removal of the device. Since the conception of implantable vascular access device ports, numerous advances in port design, materials, and techniques for implantation and care have been developed with the goal of overcoming frequent complications...
February 2018: Transfusion
https://www.readbyqxmd.com/read/29443395/subcutaneous-infusion-of-fluids-for-hydration-or-nutrition-a-review
#4
REVIEW
Riccardo Caccialanza, Thierry Constans, Paolo Cotogni, Gary P Zaloga, Alessandro Pontes-Arruda
Subcutaneous infusion, or hypodermoclysis, is a technique whereby fluids are infused into the subcutaneous space via small-gauge needles that are typically inserted into the thighs, abdomen, back, or arms. In this review, we provide an overview of the technique, summarize findings from studies that have examined the use of subcutaneous infusion of fluids for hydration or nutrition, and describe the indications, advantages, and disadvantages of subcutaneous infusion. Taken together, the available evidence suggests that, when indicated, subcutaneous infusion can be effective for administering fluids for hydration or nutrition, with minimal complications, and has similar effectiveness and safety to the intravenous route...
February 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29443394/catheter-related-bloodstream-infections-in-adults-receiving-home-parenteral-nutrition-substantial-differences-in-incidence-comparing-a-strict-microbiological-to-a-clinically-based-diagnosis
#5
Siri Tribler, Christopher F Brandt, Mark Hvistendahl, Michael Staun, Per Brøbech, Claus E Moser, Palle B Jeppesen
BACKGROUND: A common complication in patients receiving home parenteral nutrition (HPN) is catheter-related bloodstream infections (CRBSIs). The CRBSI incidence has been advocated as an outcome parameter assessing the quality of care. This study aimed to illustrate how the use of different CRBSI definitions affects the reported incidence. MATERIALS AND METHODS: In an observational study based on the Copenhagen intestinal failure database, all clinically reported CRBSIs from 2002-2013 were compared with data from the affiliated microbiological database according to recommended CRBSI criteria...
February 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29432818/differential-time-to-positivity-of-central-and-peripheral-blood-cultures-is-inaccurate-for-the-diagnosis-of-staphylococcus-aureus-long-term-catheter-related-sepsis
#6
Hanène Bouzidi, Aurélie Emirian, Antoine Marty, Elisabeth Chachaty, Agnès Laplanche, Bertrand Gachot, François Blot
OBJECTIVES: Differential time to positivity of cultures of blood drawn simultaneously from central venous catheter and peripheral sites is widely used to diagnose catheter-related bloodstream infections without removing the catheter. However, the accuracy of this technique for some pathogens such as Staphylococcus aureus is debated in routine practice. METHODS: In a 320-bed reference cancer centre, we retrospectively studied the charts of patients with at least one blood culture positive for S...
February 9, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29428697/transient-bacteremia-induced-by-dental-cleaning-is-not-associated-with-infection-of-central-venous-catheters-in-patients-with-cancer
#7
Saad Usmani, Linda Choquette, Robert Bona, Richard Feinn, Zainab Shahid, Rajesh V Lalla
OBJECTIVE: The aim of this study was to determine the incidence of bacteremia resulting from dental cleaning and of subsequent established bloodstream infection (BSI) caused by oral microorganisms in patients with cancer with central venous catheters (CVCs). STUDY DESIGN: Twenty-six patients with cancer with CVCs and absolute neutrophil count over 1000 cells/µL received dental cleaning without antibiotic prophylaxis. Periodontal status was assessed at baseline by using the Periodontal Screening and Recording (PSR) score...
January 11, 2018: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29427820/techniques-for-successful-early-retrieval-of-the-micra-transcatheter-pacing-system-a-worldwide-experience
#8
Muhammad R Afzal, Emile G Daoud, Ryan Cunnane, Shiva K Mulpuru, Alan Koay, Azlan Hussain, Razali Omar, Koh Kok Wei, Anish Amin, Gregory Kidwell, Nirav Patel, Charles Love, Michel Llyod, Maciej Sterliński, Seth Goldbarg, Miguel A Leal, James Gabriels, Apoor Patel, Ram Jadonath, Eric Grubman, George Crossley, Chris Pepper, Dhanunjaya Lakkireddy, Toshimasa Okabe, John D Hummel, Ralph S Augostini
BACKGROUND: Due to relatively newer technology, experience with retrieval of Micra transcatheter pacing system (TPS) is limited. Although, it is recommended to abandon the TPS at end of life, certain situations such as endovascular infections or device embolization warrant retrieval. OBJECTIVES: To report worldwide experience of successful retrieval for Micra TPS. METHODS: The list of all successful retrievals for the currently available leadless pacemakers (LPs) was obtained from the manufacturer of Micra TPS...
February 7, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29426705/is-a-project-needed-to-prevent-urinary-tract-infection-in-patients-admitted-to-spanish-icus
#9
F Álvarez Lerma, P Olaechea Astigarraga, X Nuvials, R Gimeno, M Catalán, M P Gracia Arnillas, I Seijas Betolaza, M Palomar Martínez
OBJECTIVE: To analyze epidemiological data of catheter-associated urinary tract infection (CAUTI) in critically ill patients admitted to Spanish ICUs in order to assess the need of implementing a nationwide intervention program to reduce these infections. DESIGN: Non-intervention retrospective annual period prevalence analysis. SETTING: Participating ICUs in the ENVIN-UCI multicenter registry between the years 2007-2016. PATIENTS: Critically ill patients admitted to the ICU with catheter-associated urinary tract infection (CAUTI)...
February 6, 2018: Medicina Intensiva
https://www.readbyqxmd.com/read/29422728/multicenter-observational-study-to-evaluate-epidemiology-and-resistance-patterns-of-common-intensive-care-unit-infections
#10
Ramesh Venkataraman, Jigeeshu V Divatia, Nagarajan Ramakrishnan, Rajesh Chawla, Pravin Amin, Palepu Gopal, Dhruva Chaudhry, Kapil Zirpe, Babu Abraham
Background: There is limited data regarding the microbiology of Intensive Care Unit (ICU)-acquired infections, such as ventilator-associated pneumonia (VAP), catheter-associated urinary tract infections (CAUTI), and catheter-related bloodstream infections (CRBSI) from India. Objectives: To explore the microbiology and resistance patterns of ICU-acquired infections and evaluate their outcomes. Materials and Methods: This was a multicenter observational study, conducted by Indian Society of Critical Care Medicine (MOSER study) between August 2011 and October 2012...
January 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29420315/prolonged-catheter-use-and-infection-in-regional-anesthesia-a-retrospective-registry-analysis
#11
Hagen Bomberg, Ina Bayer, Stefan Wagenpfeil, Paul Kessler, Hinnerk Wulf, Thomas Standl, André Gottschalk, Jens Döffert, Werner Hering, Jürgen Birnbaum, Claudia Spies, Bernd Kutter, Jörg Winckelmann, Simone Liebl-Biereige, Winfried Meissner, Oliver Vicent, Thea Koch, Daniel I Sessler, Thomas Volk, Alexander Raddatz
BACKGROUND: Prolonged catheter use is controversial because of the risk of catheter-related infection, but the extent to which the risk increases over time remains unknown. We thus assessed the time-dependence of catheter-related infection risk up to 15 days. METHODS: Our analysis was based on the German Network for Regional Anesthesia, which includes 25 centers. We considered 44,555 patients who had surgery between 2007 and 2014 and had continuous regional anesthesia as well as complete covariable details...
February 8, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29412895/executive-summary-diagnosis-and-treatment-of-catheter-related-bloodstream-infection-clinical-guidelines-of-the-spanish-society-of-clinical-microbiology-and-infectious-diseases-seimc-and-the-spanish-society-of-intensive-care-medicine-and-coronary-units-semicyuc
#12
Fernando Chaves, José Garnacho-Montero, José Luis Del Pozo, Emilio Bouza, José Antonio Capdevila, Marina de Cueto, M Ángeles Domínguez, Jaime Esteban, Nuria Fernández-Hidalgo, Marta Fernández Sampedro, Jesús Fortún, María Guembe, Leonardo Lorente, Jose Ramón Paño, Paula Ramírez, Miguel Salavert, Miguel Sánchez, Jordi Vallés
Catheter-related bloodstream infections (CRBSI) constitute an important cause of hospital-acquired infection associated with morbidity, mortality, and cost. The aim of these guidelines is to provide updated recommendations for the diagnosis and management of CRBSI in adults. Prevention of CRBSI is excluded. Experts in the field were designated by the two participating Societies (Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica and the Sociedad Española de Medicina Intensiva, Crítica y Unidades Coronarias)...
February 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29406956/diagnosis-and-treatment-of-catheter-related-bloodstream-infection-clinical-guidelines-of-the-spanish-society-of-infectious-diseases-and-clinical-microbiology-and-seimc-and-the-spanish-society-of-spanish-society-of-intensive-and-critical-care-medicine-and-coronary
#13
F Chaves, J Garnacho-Montero, J L Del Pozo, E Bouza, J A Capdevila, M de Cueto, M Á Domínguez, J Esteban, N Fernández-Hidalgo, M Fernández Sampedro, J Fortún, M Guembe, L Lorente, J R Paño, P Ramírez, M Salavert, M Sánchez, J Vallés
Catheter-related bloodstream infections (CRBSI) constitute an important cause of hospital-acquired infection associated with morbidity, mortality, and cost. The aim of these guidelines is to provide updated recommendations for the diagnosis and management of CRBSI in adults. Prevention of CRBSI is excluded. Experts in the field were designated by the two participating Societies (the Spanish Society of Infectious Diseases and Clinical Microbiology and [SEIMC] and the Spanish Society of Spanish Society of Intensive and Critical Care Medicine and Coronary Units [SEMICYUC])...
January 2018: Medicina Intensiva
https://www.readbyqxmd.com/read/29399528/anti-fouling-strategies-for-central-venous-catheters
#14
REVIEW
Alex Wallace, Hassan Albadawi, Nikasha Patel, Ali Khademhosseini, Yu Shrike Zhang, Sailendra Naidu, Grace Knuttinen, Rahmi Oklu
Central venous catheters (CVCs) are ubiquitous in the healthcare industry and carry two common complications, catheter related infections and occlusion, particularly by thrombus. Catheter-related bloodstream infections (CRBSI) are an important cause of nosocomial infections that increase patient morbidity, mortality, and hospital cost. Innovative design strategies for intravenous catheters can help reduce these preventable infections. Antimicrobial coatings can play a major role in preventing disease. These coatings can be divided into two major categories: drug eluting and non-drug eluting...
December 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/29399329/intestinal-failure-a-review
#15
REVIEW
Philip Allan, Simon Lal
Intestinal failure (IF) is the inability of the gut to absorb necessary water, macronutrients (carbohydrate, protein, and fat), micronutrients, and electrolytes sufficient to sustain life and requiring intravenous supplementation or replacement. Acute IF (types 1 and 2) is the initial phase of the illness and may last for weeks to a few months, and chronic IF (type 3) from months to years. The challenge of caring for patients with IF is not merely the management of the underlying condition leading to IF or the correct provision of appropriate nutrition or both but also the prevention of complications, whether thromboembolic phenomenon (for example, venous occlusion), central venous catheter-related bloodstream infection, IF-associated liver disease, or metabolic bone disease...
2018: F1000Research
https://www.readbyqxmd.com/read/29399286/toll-like-receptor-4-polymorphisms-and-bacterial-infections-in-patients-with-cirrhosis-and-ascites
#16
Edilmar Alvarado-Tapias, Carlos Guarner-Argente, Elida Oblitas, Elisabet Sánchez, Silvia Vidal, Eva Román, Mar Concepción, Maria Poca, Cristina Gely, Oana Pavel, Juan Camilo Nieto, Cándido Juárez, Carlos Guarner, Germán Soriano
AIM: To assess the relationship between the presence of toll-like receptor 4 (TLR4) polymorphisms and bacterial infections in cirrhotic patients with ascites. METHODS: We prospectively included consecutive patients with cirrhosis and ascites hospitalized during a 6-year period. Patients with human immunodeficiency virus (HIV) infection or any other immunodeficiency, patients with advanced hepatocellular carcinoma (beyond Milan's criteria) or any other condition determining poor short-term prognosis, and patients with a permanent urinary catheter were excluded...
January 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29395511/healthcare-associated-infections-in-the-neurological-intensive-care-unit-results-of-a-6-year-surveillance-study-at-a-major-tertiary-care-center
#17
Yasser B Abulhasan, Susan P Rachel, Marc-Olivier Châtillon-Angle, Najayeb Alabdulraheem, Ian Schiller, Nandini Dendukuri, Mark R Angle, Charles Frenette
BACKGROUND: Healthcare-associated infections (HAIs) occur frequently in neurological intensive care units (neuro-ICUs); however, data differentiating associations with various diagnostic categories and resulting burdens are limited. This prospective cohort study reported incidence rates, pathogen distribution, and patient-related outcomes of HAIs in a neuro-ICU population from April 2010 to March 2016. METHODS: Laboratory results and specific clinical indicators were used to categorize infections as per National Healthcare Safety Network nosocomial infection surveillance definitions...
January 25, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29390515/application-of-failure-mode-and-effect-analysis-in-managing-catheter-related-blood-stream-infection-in-intensive-care-unit
#18
Xixi Li, Mei He, Haiyan Wang
In this study, failure mode and effect analysis (FMEA), a proactive tool, was applied to reduce errors associated with the process which begins with assessment of patient and ends with treatment of complications. The aim of this study is to assess whether FMEA implementation will significantly reduce the incidence of catheter-related bloodstream infections (CRBSIs) in intensive care unit.The FMEA team was constructed. A team of 15 medical staff from different departments were recruited and trained. Their main responsibility was to analyze and score all possible processes of central venous catheterization failures...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29385236/strategies-to-reduce-catheter-related-bloodstream-infections-in-pediatric-patients-receiving-home-parenteral-nutrition-the-efficacy-of-taurolidine-citrate-prophylactic-locking
#19
Cecile Lambe, Catherine Poisson, Cecile Talbotec, Olivier Goulet
BACKGROUND: Catheter-related bloodstream infections (CRBSIs) remain a major issue in patients who are receiving home parenteral nutrition (HPN). The aim of this interventional study was to assess the impact of a new strategy using taurolidine-citrate (T-C) prophylactic locks on the CRBSI rate in children with intestinal failure who are receiving HPN. METHODS: The rate of CRBSIs was monitored every calendar year in a prospective cohort of 195 children with intestinal failure...
January 31, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29384980/infectious-diseases-consultation-improves-treatment-and-decreases-mortality-by-enterococcal-bacteremia-in-children
#20
Munehiro Furuichi, Mihoko Furuichi, Yuho Horikoshi, Isao Miyairi
BACKGROUND: Enterococci can cause severe infectious diseases. Delaying appropriate antibiotic therapy for enterococcal bacteremia is associated with increased patient mortality. METHODS: We conducted a retrospective analysis examining the characteristics of children with enterococcal bacteremia at the two largest children's hospitals in Japan. We compared outcomes of enterococcal bacteremia patients who received infectious diseases (ID) consultation with those who did not...
January 29, 2018: Pediatric Infectious Disease Journal
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