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Catheter-Related Infection

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https://www.readbyqxmd.com/read/29216940/-study-on-risk-factor-of-central-venous-catheter-infection-in-icu-1-160-patients-report
#1
Ming Zhang, Yongqing Xu, Zhiming Jiang, Junying Qian, Zhonghui Zhang, Nannan Sun, Jian Xie, Tao Li
OBJECTIVE: To analyze the etiology and risk factors of central venous catheter (CVCs) infections, and to explore the prophylaxis and treatment for catheter-related infections. METHODS: A retrospective study was conducted. The patients with CVCs admitted to intensive care unit (ICU) of Qianfoshan Hospital Affiliated to Shandong University from January 2000 to December 2016 were enrolled. The gender, age, catheter data and microorganism culture results of all patients were collected...
December 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29216782/reduction-in-central-line-associated-bloodstream-infections-correlated-with-the-introduction-of-a-novel-silver-plated-dressing-for-central-venous-catheters-and-maintained-for-6-years
#2
Rachel Karlnoski, Elia Charbel Abboud, Peggy Thompson, Asa Z Oxner, John T Sinnott, Jorge E Marcet
OBJECTIVE: To assess a novel silver-plated dressing (SD) for central venous catheters in comparison to chlorhexidine gluconate-impregnated sponge (CHGIS) dressings in preventing central line-associated bloodstream infections (CLABSIs) in adult intensive care unit (ICU) patients. DESIGN: Retrospective cohort study. SETTING: Tampa General Hospital, an academic medical tertiary care center. PATIENTS: All adult ICU patients of an academic medical tertiary care center from January 2009 to December 2010...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29214504/postmarketing-experience-with-neutrolin%C3%A2-taurolidine-heparin-calcium-citrate-catheter-lock-solution-in-hemodialysis-patients
#3
Bruce E Reidenberg, Christoph Wanner, Bruce Polsky, Mariana Castanheira, Alla Shelip, Dirk Stalleicken, Antony E Pfaffle
Catheter-related bloodstream infections (CRBSI) are major complications for patients with life-threatening conditions requiring chronic vascular catheterization. The wide range of etiologic microbes and the ongoing development of resistance to antimicrobials with specific mechanisms of action make this an appropriate target for applying a nonspecific antimicrobial therapeutic. Taurolidine hydrolyzes into two antimicrobial moieties, formaldehyde and methylene glycol, which react with microbial surfaces. Neutrolin® (taurolidine, heparin, calcium citrate) was recently introduced in Germany as an antimicrobial catheter lock solution...
December 6, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29214017/morphological-bactericidal-fast-acting-effects-of-peracetic-acid-a-high-level-disinfectant-against-staphylococcus-aureus-and-pseudomonas-aeruginosa-biofilms-in-tubing
#4
T Chino, Y Nukui, Y Morishita, K Moriya
Background: The bactericidal effect of disinfectants against biofilms is essential to reduce potential endoscopy-related infections caused by contamination. Here, we investigated the bactericidal effect of a high-level disinfectant, peracetic acid (PAA), against Staphylococcus aureus and Pseudomonas aeruginosa biofilm models in vitro. Methods: S. aureus and P. aeruginosa biofilms were cultured at 35 °C for 7 days with catheter tubes. The following high-level disinfectants (HLDs) were tested: 0...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29212442/impact-of-inappropriate-antifungal-therapy-according-to-current-susceptibility-breakpoints-on-candida-bloodstream-infection-mortality-a-retrospective-analysis
#5
María Fernanda González-Lara, Pedro Torres-González, Patricia Cornejo-Juárez, Consuelo Velázquez-Acosta, Areli Martinez-Gamboa, Andrea Rangel-Cordero, Miriam Bobadilla-Del-Valle, Luis Ostrosky-Zeichner, Alfredo Ponce-de-León, José Sifuentes-Osornio
BACKGROUND: The mortality of Candida Bloodstream Infection (CBSI) remains high. Antifungal susceptibility breakpoints were recently updated for Candida species, the impact remains unknown. In this study we evaluated the impact of inappropriate antifungal treatment according to recent breakpoints on 30-day mortality of CBSI. METHODS: From June 2008 to July 2014, data on CBSI episodes from two tertiary-care centers, treated > 72 h were analyzed. Antifungal therapy and 30-day mortality were registered...
December 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29211248/draft-genome-of-the-emerging-pathogen-kocuria-marina-isolated-from-a-wild-urban-rat
#6
Shih Keng Loong, Kim-Kee Tan, Nurhafiza Zainal, Wai Hong Phoon, Siti Nursheena Mohd Zain, Sazaly AbuBakar
Kocuria marina has recently emerged as a cause for catheter-related bloodstream infections in patients with underlying health complications. One K. marina strain was recently isolated from the lung tissues of a wild urban rat (Rattus rattus diardii) caught during rodent surveillance. Here, we present the draft genome of the first K. marina animal isolate, K. marina TRE150902.
December 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/29211195/impact-of-two-bundles-on-central-catheter-related-bloodstream-infection-in-critically-ill-patients
#7
Cristobal Felipe Padilla Fortunatti
OBJECTIVE: To evaluate the impact of the implementation of insertion and maintenance bundles on the rates of catheter-related bloodstream infection in an intensive care unit. METHOD: This is a quasi-experimental, before-and-after study with a non-equivalent control group. During a six-month period, insertion and maintenance bundles for the central venous catheters were implemented. Supervision guidelines were developed to assess compliance with the bundle and catheter characteristics...
December 4, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/29203484/novel-treatment-of-staphylococcus-aureus-device-related-infections-using-fibrinolytic-agents
#8
S Hogan, J P O'Gara, E O'Neill
Objective: Staphylococcal infections involving biofilms represent a significant challenge in the treatment of patients with device-related infections. Staphylococcus aureus biofilms have been shown to be SaeRS-regulated and dependent on coagulase-catalysed conversion of fibrinogen into fibrin on surfaces coated with human plasma. Here we investigated the treatment of staphylococcal biofilm device-related infections by digesting the fibrin biofilm matrix with and without existing antimicrobials.Methods: The fibrinolytic agents plasmin, streptokinase, nattokinase and the recombinant trypsin-like protease TrypLE™ were used to digest and treat S...
December 4, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29200325/incidence-and-risk-factors-of-bacterial-and-fungal-infection-during-induction-chemotherapy-for-high-risk-neuroblastoma
#9
Sarah B Whittle, Kaitlin C Williamson, Heidi V Russell
High-risk neuroblastoma is an aggressive childhood cancer with poor outcomes. Treatment begins with an induction phase comprised of intense multi-agent chemotherapy with the goal of maximally reducing tumor bulk. Given the high intensity of induction chemotherapy, neutropenic fever and infectious complications are common; however, the actual incidence is difficult to determine from clinical trial reports. We performed a retrospective review of infection-related complications in 76 children treated for high-risk neuroblastoma at Texas Children's Hospital...
December 4, 2017: Pediatric Hematology and Oncology
https://www.readbyqxmd.com/read/29198897/the-idle-central-venous-catheter-in-the-nicu-when-should-it-be-removed
#10
Cristen N Litz, Jordan G Tropf, Paul D Danielson, Nicole M Chandler
PURPOSE: There is debate regarding the optimal timing of central line removal in the neonatal intensive care unit (NICU). The purpose was to evaluate outcomes of idle peripherally inserted central catheters (PICCs) and tunneled central venous catheters (TCVCs) and determine the incidence of line-related infections and replacements. METHODS: Patients in the NICU with T-CVCs placed between 11/2008 and 8/2015 (n=134) or PICCs placed between 7/2013 and 10/2015 (n=467) were included...
November 9, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29194847/clinical-evaluation-of-the-multifunctional-suprapubic-catheter-in-patients-requiring-permanent-suprapubic-cystostomy-a-prospective-randomized-trial-in-a-single-center
#11
Hai-Jing Dong, Yi Lu, Nian-Zhao Zhang, Wen-Hua Zhang, Shuai Wu, Hui Zhao, Chang-Cun Zhang, Si-Chuan Hou
AIMS AND OBJECTIVES: To assess the clinical effect of the multifunctional suprapubic catheter (MSC) on occurrence of cystospasm, catheter occlusion, the catheter-related urinary tract infection and remission of over-activity bladder, by comparing with the conventional suprapubic catheter (CSC) in patients with permanent suprapubic cystostomy. BACKGROUND: The conventional suprapubic catheter usually presents with high incidence of catheter-associated complications...
November 30, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29189981/healthcare-associated-bloodstream-infections-in-polish-hospitals-prevalence-epidemiology-and-microbiology-summary-data-from-the-ecdc-point-prevalence-survey-of-healthcare-associated-infections-2012-2015
#12
Aleksander Deptuła, Ewa Trejnowska, Grzegorz Dubiel, Monika Wanke-Rytt, Maria Deptuła, Waleria Hryniewicz
Aggregated data from the Polish Point Prevalence Survey of Healthcare Associated Infections and Antimicrobial Use (PPS HAI&AU) collected between 2012 and 2015 were used to describe the epidemiology of healthcare associated bloodstream infections (BSI) in Polish hospitals, in order to assess the rationale for introducing a BSI surveillance programme in our country and analyse selected risk factors. Data were collected according to the ECDC PPS HAI&AU protocol. Within four years, records for 71,039 patients were collected in 36 (2012), 32 (2013), 112 (2014), and 158 (2015) hospitals; representativeness was evaluated as good in 2012-2013, and excellent from 2014...
November 30, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29188375/tunneled-pleural-catheter-use-for-pleural-palliation-does-not-increase-infection-rate-in-patients-with-treatment-related-immunosuppression
#13
Candice L Wilshire, Christopher R Gilbert, Brian E Louie, Ralph W Aye, Alexander S Farivar, Eric Vallières, Jed A Gorden
PURPOSE: Concerns for infections resulting from antineoplastic therapy-associated immunosuppression may deter referral for symptom palliation with a tunneled pleural catheter (TPC) in patients with malignant/para-malignant pleural effusions (MPE/PMPE). While rates of TPC-related infections range from 1 to 21%, those in patients receiving antineoplastic therapy with correlation to immune status has not been established. We aimed to assess TPC-related infection rates in patients on antineoplastic therapy, determine relation to immune system competency, and assess impact on the patient...
November 29, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29185601/adherence-to-central-venous-catheter-insertion-bundle-in-neonatal-and-pediatric-units
#14
Fernanda Lopes de Araújo, Bruna Figueiredo Manzo, Anna Caroline Leite Costa, Allana Dos Reis Corrêa, Juliana de Oliveira Marcatto, Delma Aurélia da Silva Simão
OBJECTIVE: To describe the observed behavior of professionals in two neonatal and pediatric intensive care units regarding the use of central venous catheter insertion bundle, and the clinical and birth profile of neonates and children who received the devices. METHOD: A quantitative descriptive exploratory study was conducted in two intensive care units of a public hospital in Belo Horizonte with neonates and children, between February and September 2016. RESULTS: The sample consisted of 59 observed implants of central venous catheter...
November 27, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/29183930/reducing-catheter-associated-urinary-tract-infections-in-hospitals-study-protocol-for-a-multi-site-randomised-controlled-study
#15
Brett G Mitchell, Oyebola Fasugba, Anne Gardner, Jane Koerner, Peter Collignon, Allen C Cheng, Nicholas Graves, Peter Morey, Victoria Gregory
INTRODUCTION: Despite advances in infection prevention and control, catheter-associated urinary tract infections (CAUTIs) are common and remain problematic. A number of measures can be taken to reduce the risk of CAUTI in hospitals. Appropriate urinary catheter insertion procedures are one such method. Reducing bacterial colonisation around the meatal or urethral area has the potential to reduce CAUTI risk. However, evidence about the best antiseptic solutions for meatal cleaning is mixed, resulting in conflicting recommendations in guidelines internationally...
November 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/29180990/the-n-terminus-of-human-lactoferrin-displays-anti-biofilm-activity-on-candida-parapsilosis-in-lumen-catheters
#16
Roberta Fais, Mariagrazia Di Luca, Cosmeri Rizzato, Paola Morici, Daria Bottai, Arianna Tavanti, Antonella Lupetti
Candida parapsilosis is a major cause of hospital-acquired infection, often related to parenteral nutrition administered via catheters and hand colonization of health care workers, and its peculiar biofilm formation ability on plastic surfaces. The mortality rate of 30% points to the pressing need for new antifungal drugs. The present study aimed at analyzing the inhibitory activity of the N-terminal lactoferrin-derived peptide, further referred to as hLF 1-11, against biofilms produced by clinical isolates of C...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29180276/dalbavancin-in-the-treatment-of-different-gram-positive-infections-a-real-life-experience
#17
Emilio Bouza, Maricela Valerio, Alex Soriano, Laura Morata, Enrique García Carus, Carmen Rodríguez-González, Ma Carmen Hidalgo-Tenorio, Antonio Plata, Patricia Muñoz, Antonio Vena
Dalbavancin is a lipoglycopeptide with a very prolonged half-life that enables treatments with a single IV administration that has been approved to treat complicated skin and soft tissue infections. Information on the efficacy and safety of Dalbavancin in other situations is very scarce. This retrospective study includes adult patients who received at least one dose of Dalbavancin between 2016 and 2017 in 29 institutions in Spain. Primary objective was to report the use of Dalbavancin in clinical practice including its efficacy and tolerability...
November 24, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29178957/triple-combination-antibiotic-therapy-for-carbapenemase-producing-klebsiella-pneumoniae-a-systematic-review
#18
REVIEW
David M Jacobs, M Courtney Safir, Dennis Huang, Faisal Minhaj, Adam Parker, Gauri G Rao
BACKGROUND: The spread of carbapenemase-producing K. pneumoniae (CPKP) has become a significant problem worldwide. Combination therapy for CPKP is encouraging, but polymyxin resistance to many antibiotics is hampering effective treatment. Combination therapy with three or more antibiotics is being increasingly reported, therefore we performed a systematic review of triple combination cases in an effort to evaluate their clinical effectiveness for CPKP infections. METHODS: The PubMed database was searched to identify all published clinical outcomes of CPKP infections treated with triple combination therapy...
November 25, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29175575/brain-granuloma-rare-complication-of-a-retained-catheter-case-report
#19
Andrea Iaquinandi, Francesco Corrivetti, Pierpaolo Lunardi, Amedeo Ferlosio, Elena Giannini, Federica Novegno
BACKGROUND: Ventriculo-peritoneal (VP) shunt is the most frequent treatment for hydrocephalus. Its malfunctioning represents one of the most common problem in neurosurgical practice, often requiring shunt revision procedures. In some cases, the complete removal of a VP shunt may present difficulties, leading the surgeon to leave the ventricular catheter in situ. This decision is often taken in order to avoid possible adverse events, first of all, life-threatening hemorrhagic risks. However, a non-functioning catheter left in the ventricular system represents a prosthetic device which may lead to further complications...
November 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29175074/staphylococcus-aureus-and-staphylococcus-epidermidis-infections-on-implants
#20
REVIEW
Weslley F Oliveira, Priscila M S Silva, Rayane C S Silva, Germana M M Silva, Giovanna Machado, Luana C B B Coelho, Maria T S Correia
BACKGROUND: Infections are one of the main reasons for removal of implants from patients, and usually need difficult and expensive treatments. Staphylococcus aureus and Staphylococcus epidermidis are the most frequent pathogens. AIM: To review the epidemiology and pathogenesis of implant-related infections. METHODS: Relevant studies were identified by electronic searching of the following databases: PubMed, ScienceDirect, Academic Google and CAPES Journal Portal...
November 21, 2017: Journal of Hospital Infection
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