keyword
MENU ▼
Read by QxMD icon Read
search

Long term affects

keyword
https://www.readbyqxmd.com/read/29165983/incorporating-electrode-modification-layer-with-vertical-phase-separated-photoactive-layer-for-efficient-and-stable-inverted-nonfullerene-polymer-solar-cells
#1
Zhenzhen Shi, Hao Liu, Yaping Wang, Jinyan Li, Yiming Bai, Fuzhi Wang, Xingming Bian, Tasawar Hayat, Ahmed Alsaedi, Zhan'ao Tan
For bulk heterojunction polymer solar cells (PSCs), the donors and acceptors featuring specific phase separation and concentration distribution within the electron donor:acceptor blends crucially affect the exciton dissociation and charge transportation. Herein, efficient and stable nonfullerene inverted PSCs incorporating phase separated photoactive layer and titanium chelate electrode modification layer are demonstrated. Water contact angle (WCA), scanning kelvin probe microscopy (SKPM), and atomic force microscopy (AFM) techniques are implemented to characterize the morphology of photoactive layers...
November 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29165412/-stabilizing-effectiveness-of-orthokeratology-and-long-term-minute-concentration-atropine-therapy-in-myopia-draft-report
#2
T Yu Verzhanskaya, E P Tarutta
The rational for the study was the high prevalence of myopia in the world. According to the World Health Organization (WHO), myopia is one of the five leading causes of blindness and low vision. Of recent reports on conservative measures for the stabilization of myopia, two areas of investigation deserve attention: methods of optical correction that affect peripheral refraction, orthokeratology lenses (OKL) in particular, and pharmacotherapy. The aim of the study was to evaluate the effectiveness and safety of myopia control in pediatric patients by combining two methods - OKL wearing and instillation of extra low doses of atropine (0...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29165127/perspectives-acquired-through-long-term-epidemiological-studies-on-the-great-east-japan-earthquake
#3
REVIEW
Toru Tsuboya, Mariko Inoue, Michihiro Satoh, Kei Asayama
The Great East Japan Earthquake (GEJE) and subsequent tsunamis that occurred in 2011 caused extensive and severe structural damage and interrupted numerous research activities; however, the majority of such activities have been revived, and further public health researches and activities have started to follow the population affected by the disaster. In this mini-review, we overview our recent activities regarding epidemiologic studies in Miyagi Prefecture, the region most affected by the GEJE. Through our study processes, we were able to identify the particular characteristics of vulnerable populations, and provide ideas that may help save lives and reduce the amount of damage caused by a future disaster...
March 15, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29165120/high-prevalence-of-dental-fluorosis-among-adolescents-is-a-growing-concern-a-school-based-cross-sectional-study-from-southern-india
#4
Anand Verma, Bharatesh K Shetty, Vasudeva Guddattu, Mehul K Chourasia, Prachi Pundir
BACKGROUND: Fluorosis, caused by ingestion of excessive amount of fluoride through food or water, is a major public health problem in India. This study was undertaken to quantify the dental fluorosis burden among school going adolescents and to find factors associated with dental fluorosis in Kolar taluka, Karnataka, India. METHODS: A total of 1026 high school adolescents (12-17 years) were enrolled from different schools selected by stratified sampling method. Dental examination was done to record Dean's fluorosis index, and socio-demographic, food consumption and oral hygiene data were recorded using a pre-tested structured questionnaire...
April 4, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29165098/effects-of-olive-oil-on-tnf-%C3%AE-and-il-6-in-humans-implication-in-obesity-and-frailty
#5
Nagendra Sastry Yarla, Angela Polito, Ilaria Peluso
BACKGROUND AND OBJECTIVE: Tumor necrosis factor-alpha (TNF)-α and interleukin (IL)-6 are important mediators of chronic low-grade systemic inflammation. The latter plays a central role in several obesity-related pathologies, such as diabetes, metabolic syndrome and cardiovascular diseases. Besides, these cytokines have been also implicated in geriatric and cancer-induced anorexia, cachexia, sarcopenia and frailty. Potential interventions for both obesity and frailty include dietary advice and nutraceuticals...
November 20, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29164869/role-of-secondary-particle-formation-in-the-persistence-of-silver-nanoparticles-in-humic-acid-containing-water-under-light-irradiation
#6
Tuoya Zhang, Dawei Lu, Lixi Zeng, Yongguang Yin, Yujian He, Qian Liu, Guibin Jiang
The wide use of silver nanoparticles (AgNPs) leads to the increasing release of AgNPs into the environment. Dissolved organic matter (DOM) is a key factor affecting the behaviors and fate of AgNPs in the aquatic environment. However, the mechanisms for the DOM-mediated transformations of AgNPs are still not fully understood. In this study, we investigated the persistence of AgNPs in aquatic environment in the presence of different concentrations of humic acid (HA) over periods of time up to 14 days. The Ag species were monitored and characterized by absorption spectrometry, transmission electron microscopy (TEM), inductively coupled plasma mass spectrometry (ICP-MS), and multicollector ICP-MS (MC-ICP-MS)...
November 22, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29164664/can-sleep-quality-and-burnout-affect-the-job-performance-of-shift-work-nurses-a-hospital-cross-sectional-study
#7
Fabio Giorgi, Antonella Mattei, Ippolito Notarnicola, Cristina Petrucci, Loreto Lancia
AIM: The aim of this study was to investigate any possible relationship between sleep disorders, burnout and job performance in a shift-work population of nurses. BACKGROUND: Sleep disorders and burnout can affect the job performance of nurses in terms of efficiency, productivity, task execution speed and supervision, which can be compromised when work shifts are organized on a 24-hour schedule and when the shift itself is irregular. DESIGN: A cross-sectional observational study was conducted from August 2014 - January 2015 on a sample of 315 shift-work nurses across 39 wards in seven central Italian hospitals...
November 22, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29164430/eclalbasaponin-ii-ameliorates-the-cognitive-impairment-induced-by-cholinergic-blockade-in-mice
#8
Won Yong Jung, Haneul Kim, Se Jin Jeon, Hye Jin Park, Hyuck Jai Choi, Nam Jae Kim, Dong Hyun Kim, Dae Sik Jang, Jong Hoon Ryu
Eclalbasaponin II derived from Eclipta prostrata L. (Asteraceae) has been reported to have anti-fibrotic, anti-bacterial and autophagic activities, but its effect on cognitive function has not been investigated. We studied the effect of eclalbasaponin II on cholinergic blockade-induced memory impairment in mice using the passive avoidance, Y-maze, and Morris water maze tasks. Eclalbasaponin II (10 or 20 mg/kg, p.o.) significantly ameliorated the cognitive dysfunction induced by scopolamine in the passive avoidance, Y-maze, and the Morris water maze tasks...
November 21, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/29164130/comparison-of-an-innovative-rehabilitation-combining-reduced-conventional-rehabilitation-with-balneotherapy-and-a-conventional-rehabilitation-after-anterior-cruciate-ligament-reconstruction-in-athletes
#9
Laetitia Peultier-Celli, Didier Mainard, Frank Wein, Nicolas Paris, Patrick Boisseau, Alexandre Ferry, René Gueguen, Isabelle Chary-Valckenaere, Jean Paysant, Philippe Perrin
Background: Instability of the knee, related to anterior cruciate ligament injury, is treated by surgical reconstruction. During recovery, a loss of proprioceptive input can have a significant impact. Few studies have evaluated the benefits of rehabilitation of the knee in aquatic environment on functional outcomes. Objective: This study aimed to compare an innovative rehabilitation protocol combining reduced conventional rehabilitation with aquatic rehabilitation, with a conventional rehabilitation, according to the National French Health Authority, in terms of kinetics, development of proprioceptive skills, and functional improvement of the knee...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29164116/potential-of-metformin-to-improve-cardiac-risk-in-postpartum-women-with-gestational-diabetes
#10
Oscar A Viteri, Mary Alice Sallman, Pauline M Berens, Pamela D Berens, Farah H Amro, Maria S Hutchinson, Susan M Ramin, Sean C Blackwell, Jerrie S Refuerzo, Judith A Smith
Objective: Pregnancy is associated with an increase in total cholesterol, high density lipoproteins (HDL), and low-density lipoproteins (LDL). Postpartum, HDL and LDL decrease over the first 12 weeks postpartum. Oxidized LDL (ox-LDL) is a marker of oxidative stress-related inflammation, which is associated with obesity and also with development of cardiovascular disease. Cardiovascular protection and weight loss are benefits from metformin, especially in women with diabetes. The objective of this study was to compare changes in lipid profiles and biomarkers for obesity during the initial 6 weeks postpartum between women with gestational diabetes mellitus (GDM) treated with metformin versus placebo...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29164045/factors-related-to-healthcare-service-quality-in-long-term-care-hospitals-in-south-korea-a-mixed-methods-study
#11
Minsung Sohn, Mankyu Choi
Objectives: The environment of long-term care hospitals (LTCHs) is critical to the management of the quality of their services and to patient safety, as highlighted by international studies. However, there is a lack of evidence on this topic in South Korea. This study aimed to examine the factors affecting healthcare quality in LTCHs and to explore the effectiveness of their quality management. Methods: This study used a mixed methods approach with quantitative data collected in a national survey and qualitative data from semi-structured interviews with practice-based managers...
October 2017: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/29164001/paradoxical-elevation-of-serum-tracp5b-levels-despite-increase-in-lumbar-spine-bone-mineral-density-during-anti-tnf%C3%AE-therapy-in-patients-with-inflammatory-rheumatic-disease-a-2-year-prospective-assessment-of-bone-mass-bone-metabolism-and-the-trabecular-bone
#12
Éric Toussirot, Laurent Mourot, Barbara Dehecq, Fabrice Michel, Daniel Wendling, Émilie Grandclément, Gilles Dumoulin
Objective: To examine the impact of long-term anti-TNFα therapy on bone mass, bone metabolism, and the trabecular bone score (TBS) in patients with rheumatoid arthritis (RA) or ankylosing spondylitis (AS). Material and Methods: In eight patients with RA and 12 with AS, bone mineral densities (BMDs) of the lumbar spine (LS), left and right femoral neck, and total skeleton were measured using dual X-ray absorptiometry at baseline and then at 6, 12, and 24 months after anti TNFα therapy...
September 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/29163347/long-term-treatment-benefits-and-prolonged-efficacy-of-onabotulinumtoxina-in-patients-affected-by-chronic-migraine-and-medication-overuse-headache-over-3%C3%A2-years-of-therapy
#13
Simona Guerzoni, Lanfranco Pellesi, Carlo Baraldi, Michela Maria Cainazzo, Andrea Negro, Paolo Martelletti, Luigi Alberto Pini
Background: Chronic migraine (CM) affects about the 2% of the general population and it has been recognized as one of the most-disabling conditions worldwide by the World Health Organization. CM is often associated with the overuse of abortive medication, which determines the worsening of headache itself and the development of a secondary headache called medication overuse headache. The management of these associated conditions is difficult, but a growing amount of evidence is pointing out the effectiveness and the good safety profile of OnabotulinumtoxinA (OnabotA)...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29163336/two-novel-mutations-associated-with-ataxia-telangiectasia-identified-using-an-ion-ampliseq-inherited-disease-panel
#14
Maria V Kuznetsova, Dmitry Yu Trofimov, Ekaterina S Shubina, Taisiya O Kochetkova, Natalia A Karetnikova, Ilya Yu Barkov, Vladimir A Bakharev, Oleg A Gusev, Gennady T Sukhikh
Ataxia-telangiectasia (A-T), or Louis-Bar syndrome, is a rare neurodegenerative disorder associated with immunodeficiency. For families with at least one affected child, timely A-T genotyping during any subsequent pregnancy allows the parents to make an informed decision about whether to continue to term when the fetus is affected. Mutations in the ATM gene, which is 150 kb long, give rise to A-T; more than 600 pathogenic variants in ATM have been characterized since 1990 and new mutations continue to be discovered annually...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29163185/orthostatic-intolerance-in-older-persons-etiology-and-countermeasures
#15
REVIEW
Nandu Goswami, Andrew P Blaber, Helmut Hinghofer-Szalkay, Jean-Pierre Montani
Orthostatic challenge produced by upright posture may lead to syncope if the cardiovascular system is unable to maintain adequate brain perfusion. This review outlines orthostatic intolerance related to the aging process, long-term bedrest confinement, drugs, and disease. Aging-associated illness or injury due to falls often leads to hospitalization. Older patients spend up to 83% of hospital admission lying in bed and thus the consequences of bedrest confinement such as physiological deconditioning, functional decline, and orthostatic intolerance represent a central challenge in the care of the vulnerable older population...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29163086/adolescent-exposure-to-methylphenidate-increases-impulsive-choice-later-in-life
#16
Zarish Abbas, Arwen Sweet, Giovanni Hernandez, Andreas Arvanitogiannis
Background: The psychostimulant methylphenidate (MPH) is known to temporarily reduce impulsive choice and promote self-control. What is not sufficiently understood is how repeated treatment with MPH affects impulsive choice in the long run, and whether any such effect is contingent on exposure at certain developmental stages. Methods: Using an animal model for impulsive choice, we examined first whether giving MPH through early adolescence alters delay discounting, an operational measure of impulsive choice, later in adulthood...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29163061/cyclodextrins-and-iatrogenic-hearing-loss-new-drugs-with-significant-risk
#17
REVIEW
Mark A Crumling, Kelly A King, R Keith Duncan
Cyclodextrins are a family of cyclic oligosaccharides with widespread usage in medicine, industry and basic sciences owing to their ability to solubilize and stabilize guest compounds. In medicine, cyclodextrins primarily act as a complexing vehicle and consequently serve as powerful drug delivery agents. Recently, uncomplexed cyclodextrins have emerged as potent therapeutic compounds in their own right, based on their ability to sequester and mobilize cellular lipids. In particular, 2-hydroxypropyl-β-cyclodextrin (HPβCD) has garnered attention because of its cholesterol chelating properties, which appear to treat a rare neurodegenerative disorder and to promote atherosclerosis regression related to stroke and heart disease...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29163002/serotonin-coordinates-responses-to-social-stress-what-we-can-learn-from-fish
#18
REVIEW
Tobias Backström, Svante Winberg
Social interaction is stressful and subordinate individuals are often subjected to chronic stress, which greatly affects both their behavior and physiology. In teleost fish the social position of an individual may have long-term effects, such as effects on migration, age of sexual maturation or even sex. The brain serotonergic system plays a key role in coordinating autonomic, behavioral and neuroendocrine stress responses. Social subordination results in a chronic activation of the brain serotonergic system an effect, which seems to be central in the subordinate phenotype...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29162872/european-catfish-silurus-glanis-as-a-freshwater-apex-predator-drives-ecosystem-via-its-diet-adaptability
#19
Lukáš Vejřík, Ivana Vejříková, Petr Blabolil, Antti P Eloranta, Luboš Kočvara, Jiří Peterka, Zuzana Sajdlová, Son Hoang The Chung, Marek Šmejkal, Mikko Kiljunen, Martin Čech
Apex predators play a key role in ecosystem stability across environments but their numbers in general are decreasing. By contrast, European catfish (Silurus glanis), the European freshwater apex predator, is on the increase. However, studies concerning apex predators in freshwaters are scarce in comparison to those in terrestrial and marine ecosystems. The present study combines stomach content and stable isotope analyses with diet preferences of catfish to reveal its impact on the ecosystem since stocking...
November 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29162833/the-combination-of-chk1-inhibitor-with-g-csf-overrides-cytarabine-resistance-in-human-acute-myeloid-leukemia
#20
Alessandro Di Tullio, Kevin Rouault-Pierre, Ander Abarrategi, Syed Mian, William Grey, John Gribben, Aengus Stewart, Elizabeth Blackwood, Dominique Bonnet
Cytarabine (AraC) represents the most effective single agent treatment for AML. Nevertheless, overriding AraC resistance in AML remains an unmet medical need. Here we show that the CHK1 inhibitor (CHK1i) GDC-0575 enhances AraC-mediated killing of AML cells both in vitro and in vivo, thus abrogating any potential chemoresistance mechanisms involving DNA repair. Importantly, this combination of drugs does not affect normal long-term hematopoietic stem/progenitors. Moreover, the addition of CHK1i to AraC does not generate de novo mutations and in patients' samples where AraC is mutagenic, addition of CHK1i appears to eliminate the generation of mutant clones...
November 22, 2017: Nature Communications
keyword
keyword
1006
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"