keyword
MENU ▼
Read by QxMD icon Read
search

Long term affects

keyword
https://www.readbyqxmd.com/read/28549285/environmental-response-to-long-term-mariculture-activities-in-the-weihai-coastal-area-china
#1
Hongmei Li, Xiaomin Li, Qiang Li, Ying Liu, Jide Song, Yongyu Zhang
The environmental impacts of rapid expansion of mariculture have garnered worldwide attention. China is currently one of the largest countries to engage in this practice. In this study, a representative mariculture zone, the Weihai coastal area in China, was explored to determine the temporal variations in regional nutrients, N/P ratio, dissolved oxygen (DO), pH, chlorophyll a (Chl-a), and cellular abundance of diatoms and dinoflagellates in response to the rapid growth in mariculture activities between 2006 and 2014...
May 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28549284/long-term-results-of-the-toefit-plus-replacement-for-first-metatarsophalangeal-joint-arthritis
#2
REVIEW
Shreekant Gupta, Saqib Masud
Hallux rigidus is osteoarthritis affecting the metatarsophalangeal joint of the first toe. Patients often complain of pain and stiffness with pain being aggravated by walking, particularly during toe-off in the gait cycle. Osteoarthritis of the metatarsophalangeal joint is commonly treated with arthrodesis or resection arthroplasty. Metallic replacement of this joint is used sometimes but is not widely accepted. The use of silastic joints has problems with synovitis and implant failure. The authors used titanium implants, which can be screwed into the metatarsal and phalanx, allowing good fixation without the use of bone cement...
May 8, 2017: Foot
https://www.readbyqxmd.com/read/28548900/corticosterone-response-as-an-age-specific-mediator-of-nestling-body-mass-in-a-wild-passerine
#3
Vallo Tilgar, Marianne Lind, Jaanis Lodjak, Kadri Moks
The environment can affect individual performance directly via resource availability or indirectly through resource allocation among competing fitness components, such as body growth and maintenance activities related to short-term survival. Corticosterone (CORT), the main glucocorticoid in birds, may be an important mediator of energy allocation to different organismal functions, but its effect on the plasticity of fitness-related traits has rarely been investigated at different ontogenetic stages. Here, we evaluated the role of baseline and stress-induced CORT on nestling development of wild great tits (Parus major) under different growth conditions and at different developmental stages...
July 2017: Physiological and Biochemical Zoology: PBZ
https://www.readbyqxmd.com/read/28548626/correlates-of-protection-for-inactivated-enterovirus-71-vaccine-the-analysis-of-immunological-surrogate-endpoints
#4
Wenbo Zhu, Pengfei Jin, Jing-Xin Li, Feng-Cai Zhu, Pei Liu
BACKGROUND: Inactivated Enterovirus 71 (EV71) vaccines showed significant efficacy against the diseases associated with EV71 and a neutralizing antibody (NTAb) titer of 1:16-1:32 was suggested as the correlates of the vaccine protection. This paper aims to further estimate the immunological surrogate endpoints for the protection of inactivated EV71 vaccines and the effect factors. METHOD: Pre-vaccination NTAb against EV71 at baseline (day 0), post-vaccination NTAb against EV71 at day 56, and the occurrence of laboratory-confirmed EV71-associated diseases during a 24-months follow-up period were collected from a phase 3 efficacy trial of an inactivated EV71 vaccine...
May 26, 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28548599/an-extent-of-resection-threshold-for-seizure-freedom-in-patients-with-low-grade-gliomas
#5
David S Xu, Al-Wala Awad, Chad Mehalechko, Jeffrey R Wilson, Lynn S Ashby, Stephen W Coons, Nader Sanai
OBJECTIVE Seizures are the most common presenting symptom of newly diagnosed WHO Grade II gliomas (low-grade glioma [LGG]) and significantly impair quality of life. Although gross-total resection of LGG is associated with better seizure control, it remains unclear whether an extent of resection (EOR) "threshold" exists for long-term seizure control. Specifically, what proportion of FLAIR-positive tissue in patients with newly diagnosed LGG must be removed to achieve Engel Class I seizure freedom? To clarify the EOR threshold for long-term seizure control, the authors analyzed data from a consecutive series of patients with newly diagnosed LGG who presented with seizures and subsequently underwent microsurgical resection...
May 26, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28548471/recurrent-mitral-paravalvular-leak-benefits-of-leak-site-repair-compared-to-re-replacement
#6
Jae-Woong Choi, Ho Y Hwang, Kyung H Kim, Ki-Bong Kim, Hyuk Ahn
BACKGROUND: Mitral paravalvular leak (PVL) recurrence after surgical correction has not yet been well demonstrated. The aims of this study were (1) to evaluate the long-term results of surgical mitral PVL correction, including recurrent PVL, and (2) to elucidate the factors including surgical technique that affect the risk of recurrent PVL. METHODS: Eighty-six patients who underwent surgical treatment for mitral PVL were enrolled in this study. Thirty-six patients underwent leak site repair (MVP group), and 50 patients underwent re-replacement (MVR group)...
May 26, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28548278/neuropeptide-s-precursor-knockout-mice-display-memory-and-arousal-deficits
#7
Xiaobin Liu, Wei Si, Celia Garau, Kay Jüngling, Hans-Christian Pape, Stefan Schulz, Rainer K Reinscheid
Activation of Neuropeptide S (NPS) signaling has been found to produce arousal, wakefulness, anxiolytic-like behaviors and enhanced memory formation. In order to further study physiological functions of the NPS system, we generated NPS precursor knockout mice by homologous recombination in embryonic stem cells. NPS(-/-) mice were viable, fertile, and anatomically normal, when compared to their wildtype and heterozygous littermates. The total number of NPS neurons - although no longer synthesizing the peptide - was not affected by the knockout, as analyzed in NPS(-/-) /NPS(EGFP) double-transgenic mice...
May 26, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28548184/obesity-and-kidney-disease-hidden-consequences-of-the-epidemic
#8
Csaba P Kovesdy, Susan Furth, Carmine Zoccali
Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade. This increasing prevalence has implications for the risk of diabetes, cardiovascular disease and also for Chronic kidney disease. A high body mass index is one of the strongest risk factors for new-onset Chronic kidney disease. In individuals affected by obesity, a compensatory hyperfiltration occurs to meet the heightened metabolic demands of the increased body weight. The increase in intraglomerular pressure can damage the kidneys and raise the risk of developing Chronic kidney disease in the long-term...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28547910/impact-of-delayed-gastric-emptying-following-pancreaticoduodenectomy-on-survival
#9
Yasuro Futagawa, Masaru Kanehira, Kenei Furukawa, Hiroaki Kitamura, Seiya Yoshida, Teruyuki Usuba, Takeyuki Misawa, Tomoyoshi Okamoto, Katsuhiko Yanaga
BACKGROUND: Delayed gastric emptying (DGE), a common postoperative complication of pancreaticoduodenectomy (PD), is not considered a life-threatening complication. In this study, we analyzed the risk factors for DGE and its impact on long-term prognosis. METHODS: We analyzed 383 patients who underwent PD between 2003 and 2010, dividing them into two groups according to DGE grade as defined by the International Study Group of Pancreatic Surgery: 243 without DGE (Non-DGE Group) and 140 with DGE of any grade (DGE Group)...
May 26, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28547750/management-of-long-term-therapy-with-biological-drugs-in-psoriatic-patients-with-latent-tuberculosis-infection-in-real-life-setting
#10
Andrea Conti, Stefano Piaserico, Paolo Gisondi, Giulia Odorici, Giovanna Galdo, Claudia Lasagni, Giovanni Pellacani
Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs. The aim of this study is to investigate the safety and efficacy of prophylaxis of LTBI in psoriatic patients receiving long-term biological drugs. The study included 56 patients (42 male and 14 female) affected by moderate-to-severe psoriasis (mean PASI: 12.8 ± 6.9 SD) treated with anti-TNF-α and/or anti IL 12, 23 and/or anti-CD11 drugs with a diagnosis of LTBI. LTBI diagnosis was based on tuberculin skin test and/or QuantiFERON TB Gold test positivity and chest X-ray suggestive, without clinical, or microbiological evidence of active disease...
May 26, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28547576/thoraco-lumbar-selective-fusion-in-adolescent-idiopathic-scoliosis-with-lenke-c-modifier-curves-clinical-and-radiographic-analysis-at-10-year-follow-up
#11
Laura Scaramuzzo, Fabrizio Giudici, Daniele Bongetta, Eleonora Caboni, Leone Minoia, Antonino Zagra
PURPOSE: To examine the radiological and clinical outcomes of a single-center case series of selective thoracic fusions (STF) in adolescent idiopathic scoliosis with Lenke C modifier curves, with a long-term follow-up. METHODS: We evaluated at 6 months and 10 years different radiological parameters on both thoracic and lumbar districts: coronal curves, sagittal curves, apical vertebral translation (AVT), and apical vertebral rotation (AVR). The clinical outcome was determined using the SRS 22 score...
May 25, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28547179/telomere-length-measurement-by-qpcr-in-birds-is-affected-by-storage-method-of-blood-samples
#12
Sophie Reichert, Hannah Froy, Winnie Boner, Theresa M Burg, Francis Daunt, Robert Gillespie, Kate Griffiths, Sue Lewis, Richard A Phillips, Dan H Nussey, Pat Monaghan
Given the potential role of telomeres as biomarkers of individual health and ageing, there is an increasing interest in studying telomere dynamics in a wider range of taxa in the fields of ecology and evolutionary biology. Measuring telomere length across the lifespan in wild animal systems is essential for testing these hypotheses, and may be aided by archived blood samples collected as part of longitudinal field studies. However, sample collection, storage, and DNA extraction methods may influence telomere length measurement, and it may, therefore, be difficult to balance consistency in sampling protocol with making the most of available samples...
May 25, 2017: Oecologia
https://www.readbyqxmd.com/read/28546772/the-impact-of-socioeconomic-status-and-multimorbidity-on-mortality-a-population-based-cohort-study
#13
Nikoline Lund Jensen, Henrik Søndergaard Pedersen, Mogens Vestergaard, Stewart W Mercer, Charlotte Glümer, Anders Prior
OBJECTIVE: Multimorbidity (MM) is more prevalent among people of lower socioeconomic status (SES), and both MM and SES are associated with higher mortality rates. However, little is known about the relationship between SES, MM, and mortality. This study investigates the association between educational level and mortality, and to what extent MM modifies this association. METHODS: We followed 239,547 individuals invited to participate in the Danish National Health Survey 2010 (mean follow-up time: 3...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28545916/long-term-success-and-failure-with-sg-is-predictable-by-3-months-a-multivariate-model-using-simple-office-markers
#14
Austin Cottam, Josiah Billing, Daniel Cottam, Peter Billing, Samuel Cottam, Hinali Zaveri, Amit Surve
INTRODUCTION: Despite being the most common surgery in the United States, little is known about predicting weight loss success and failure with sleeve gastrectomy (SG). Papers that have been published are inconclusive. We decided to use multivariate analysis from 2 practices to design a model to predict weight loss outcomes using data widely available to any surgical practice at 3 months to determine weight loss outcomes at 1 year. SETTING: Two private practices in the United States...
March 23, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28545461/interventions-to-reduce-inequalities-in-health-and-early-child-development-in-europe-from-a-qualitative-perspective
#15
Joana Morrison, Hynek Pikhart, Peter Goldblatt
BACKGROUND: Early childhood is a critical stage of development. Inequalities in experiences affect children's wellbeing and determine their development. Early years interventions focusing on children and their parents may help address inequalities during this critical period. Understanding the experiences and perceptions of parents receiving early years programmes and staff providing these may help service development and delivery. The objective of this study was to describe staff and parents' accounts of how early childhood programmes in different European country contexts improved child development...
May 25, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28545157/the-aminoestrogen-prolame-increases-recognition-memory-and-hippocampal-neuronal-spine-density-in-aged-mice
#16
Alfonso Diaz, Samuel Treviño, Rubén Vázquez-Roque, Berenice Venegas, Blanca Espinosa, Gonzalo Flores, Juan Manuel Fernández-G, Luis F Montaño, Jorge Guevara
The aging brain shows biochemical and morphological changes in the dendrites of pyramidal neurons from the limbic system associated with memory loss. Prolame (N-(3-hydroxy-1,3,5 (10) -estratrien-17β-yl) -3-hydroxypropylamine) is a non-feminizing aminoestrogen with antithrombotic activity that prevents neuronal deterioration, oxidative stress and neuroinflammation. Our aim was to evaluate the effect of prolame on motor and cognitive processes, as well as its influence on the dendritic morphology of neurons at the CA1, CA3 and granule cells of the dentate gyrus (DG) regions of hippocampus (HP), and medium spiny neurons of the nucleus accumbens (NAcc) of aged mice...
May 25, 2017: Synapse
https://www.readbyqxmd.com/read/28544667/effect-of-the-long-term-administration-of-cyclosporine-a-on-bone-healing-around-osseointegrated-titanium-implants-a-histomorphometric-study-in-the-rabbit-tibia
#17
Rafael Scaf de Molon, Celso Eduardo Sakakura, Rafael Silveira Faeda, Rafael Sartori, Daniel Palhares, Rogerio Margonar, Elcio Marcantonio
The aim of this study was to investigate the effect of cyclosporine A (CsA) therapy on bone healing around osseointegrated implants in the rabbit by means of descriptive histologic and histomorphometric analyses. Eighteen rabbits received one implant each in the right tibia proximal metaphysis. After the bone-healing period of 3 months, 6 randomly selected animals were sacrificed (Group CTL-12) before the immunosuppression therapy initiation to obtain a standard of implant integration. Another six randomly selected animals were submitted to a daily subcutaneous (sc) injection of 10 mg/kg CsA (Group CsA) whereas the six remaining animals received daily sc injections of saline solution (Group CTL-24)...
May 22, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28544314/low-intensity-endurance-exercise-plus-nandrolone-decanoate-modulates-cardiac-adiponectin-and-its-receptors
#18
A Karimi, S Joukar, H Najafipour, Y Masoumi-Ardakani, B Shahouzehi
Vast adverse effects of anabolic-androgenic steroids (AASs) on athletes' cardiovascular systems have been reported. However, there is still a lack of adequate information regarding the pathways and mechanisms involved. We tested the hypothesis that adiponectin and its receptors in the heart may be affected by long-term use of AASs alongside exercising. Male Wistar rats were randomized into the control (CTL), exercise (EX), nandrolone (Nan), arachis (Arach) group which treated with arachis as vehicle, trained vehicle (EX+Arach) and trained nandrolone (EX+Nan) groups that were treated for 8 weeks...
March 2017: Autonomic & Autacoid Pharmacology
https://www.readbyqxmd.com/read/28544229/clinical-heterogeneity-of-type-1-diabetes-t1d-found-in-asia
#19
REVIEW
Yongsoo Park, Kupper A Wintergerst, Zhiguang Zhou
Diabetes mellitus among young patients in Asia is caused by a complex set of factors. Although T1D remains the most common form of diabetes in children, the recent unabated increase in obesity has resulted in the emergence of T2D as a new type of diabetes at adolescent and young adult age. In addition to the typical autoimmune type 1 diabetes (T1aD) and type 2 diabetes (T2D) patients, there is a variable incidence of cases of non-autoimmune types of T1D associated with insulin deficiency (T1bD). Additional forms have been described, including fulminant T1D (FT1D)...
May 19, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/28543873/effect-of-surgery-vs-observation-skeletal-5-year-outcomes-in-a-randomized-trial-of-patients-with-primary-hpt-the-siph-study
#20
Karolina Lundstam, Ansgar Heck, Kristin Godang, Charlotte Mollerup, Marek Baranowski, Ylva Pernow, Turid Aas, Ola Hessman, Thord Rosén, Jörgen Nordenström, Svante Jansson, Mikael Hellström, Jens Bollerslev
Mild primary hyperparathyroidism (PHPT) is known to affect the skeleton, even though patients usually are asymptomatic. Treatment strategies have been widely discussed. However, long-term randomized studies comparing parathyroidectomy to observation are lacking. The objective was to study the effect of parathyroidectomy (PTX) compared to observation (OBS) on bone mineral density (BMD) in g/cm(2) and T-scores, and on biochemical markers of bone turnover (P1NP and CTX-1), in a prospective randomized controlled study of patients with mild PHPT after 5 years of follow-up...
May 25, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
keyword
keyword
1006
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"