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Blood sugar monitoring

Zaid Abassi, Jonatan Leor, Natalie Landa, Firas Younis, Kenneth Hollander, Eric Mayoux, Lea Rath-Wolfson, Talma Rosenthal
OBJECTIVE: Hypertension and Diabetes commonly coexist and have been implicated in deterioration of kidneys, heart and impairment of pancreas. Empagliflozin (Empa), a selective SGLT2 inhibitor, is a new agent for treatment of diabetes via enhancing glucosuria, independent of insulin resistance. This study evaluates Empa's prophylactic beneficial effect on glomerular, cardiac and pancreatic integrity, in CRDH animals. DESIGN AND METHOD: Cohen Rosenthal Diabetic Hypertensive rats (CRDH) were divided into 3 groups: A- Sugar diet (SD) + Empa, B-Sugar Diet + Veh, C-Regular Chow + Veh (Control)...
September 2016: Journal of Hypertension
H M M Herath, T P Weerarathna, C L Fonseka, A S Vidanagamage
INTRODUCTION: Recent studies indicate that modulation of post prandial blood sugar (PPBS) plays an important role in the long term glycemic control. Measurement of PPBS is more convenient for patients attending outpatient clinics than fasting blood sugar (FBS) as the former needs only two hours of fasting from the last meal. OBJECTIVE: To assess the value of PPBS monitoring in optimization of long term glycemic control among diabetic patients attending an outpatient clinic...
October 5, 2016: Diabetes & Metabolic Syndrome
Anjana Hulse, Suahma Rai, K M Prasanna Kumar
BACKGROUND: In children with type 1 diabetes, intensive diabetes management has been demonstrated to reduce long-term microvascular complications. At present, self-monitoring of blood glucose (SMBG) by patients at home and glycated hemoglobin estimation every 3 months are used to monitor glycemic control in children. Recently, ambulatory glucose profile (AGP) is increasingly being used to study the glycemic patterns in adults. However, accuracy and reliability of AGP in children have not been evaluated yet...
September 2016: Indian Journal of Endocrinology and Metabolism
Abdullah K Al-Hwiesh, Ibrahiem S Abdul-Rahman, Abdul-Salam Noor, Mohammed A Nasr-El-Deen, Abdalla Abdelrahman, Tamer S El-Salamony, Fahd A Al-Muhanna, Khalid M Al-Otaibi, Nehad Al-Audah
♦ Objective: Metformin continues to be the safest and most widely used antidiabetic drug. In spite of its well-known benefits; metformin use in end-stage renal disease (ESRD) patients is still restricted. Little has been reported about the effect of peritoneal dialysis (PD) on metformin clearance and the phantom of lactic acidosis deprives ESRD patients from metformin therapeutic advantages. Peritoneal dialysis is probably a safeguard against lactic acidosis, and it is likely that using this drug would be feasible in this group of patients...
September 28, 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Kelly Martinez, Sharon F Frazer, Martin Dempster, Andrea Hamill, Hanora Fleming, Noleen K McCorry
This review aims to synthesise the literature examining the psychosocial variables related to self-management (insulin adherence, non-adherence and administration, blood sugar monitoring, dietary behaviour, exercise behaviour) in adolescents with type 1 diabetes. A systematic search of three electronic databases was carried out and, after the application of eligibility criteria, 21 articles were assessed for quality prior to data extraction. Numerous psychological factors were found to be associated with self-management; however, correlations were typically small to moderate...
September 22, 2016: Journal of Health Psychology
Zaid Abassi, Jonatan Leor, Natalie Landa, Firas Younis, Kenneth Hollander, Eric Mayoux, Lea Rath-Wolfson, Talma Rosenthal
OBJECTIVE: Hypertension and Diabetes commonly coexist and have been implicated in deterioration of kidneys, heart and impairment of pancreas. Empagliflozin (Empa), a selective SGLT2 inhibitor, is a new agent for treatment of diabetes via enhancing glucosuria, independent of insulin resistance. This study evaluates Empa's prophylactic beneficial effect on glomerular, cardiac and pancreatic integrity, in CRDH animals. DESIGN AND METHOD: Cohen Rosenthal Diabetic Hypertensive rats (CRDH) were divided into 3 groups: A- Sugar diet (SD) + Empa, B-Sugar Diet + Veh, C-Regular Chow + Veh (Control)...
September 2016: Journal of Hypertension
Cai Le, Su Rong, You Dingyun, Cui Wenlong
BACKGROUND: This study examines how socioeconomic factors are associated with prevalence and self-management of diabetes among ethnic minority groups in the rural Yunnan province, which has the most ethnic minority groups per province in southwest China. METHODS: A cross-sectional survey was carried out in 2014 in a rural southwest population consisting of 5532 consenting individuals aged ⩾35years. Information about participants' demographic characteristics, as well as diabetes diagnosis, treatment, and self-management behaviors, were obtained using a standard questionnaire...
August 31, 2016: Diabetes Research and Clinical Practice
Sununta Youngwanichsetha, Sasitorn Phumdoung
AIMS AND OBJECTIVES: To explore and describe lived experience of blood glucose self-monitoring among pregnant Thai women with gestational diabetes mellitus. BACKGROUND: Self- monitoring of blood glucose is an essential practice among pregnant women with diabetes in order to prevent complications in pregnancy and the newborn infant. DESIGN: Phenomenological research was employed to understand lived experiences in glycemic control. METHODS: Thirty participants were approached and interviewed using a semi-structured interview guides...
September 7, 2016: Journal of Clinical Nursing
Koji Sode, Noya Loew, Yosuke Ohnishi, Hayato Tsuruta, Kazushige Mori, Katsuhiro Kojima, Wakako Tsugawa, Jeffrey T LaBelle, David C Klonoff
In this study, a novel fungus FAD dependent glucose dehydrogenase, derived from Aspergillus niger (AnGDH), was characterized. This enzyme's potential for the use as the enzyme for blood glucose monitor enzyme sensor strips was evaluated, especially by investigating the effect of the presence of xylose during glucose measurements. The substrate specificity of AnGDH towards glucose was investigated, and only xylose was found as a competing substrate. The specific catalytic efficiency for xylose compared to glucose was 1...
August 18, 2016: Biosensors & Bioelectronics
Natalija Topić Popović, Ivančica Strunjak-Perović, Josip Barišić, Slavko Kepec, Margita Jadan, Blanka Beer-Ljubić, Vesna Matijatko, Dušan Palić, Goran Klobučar, Sanja Babić, Jasenka Gajdoš Kljusurić, Rozelindra Čož-Rakovac
The aim of this study was to assess the impact of treated wastewaters on native wild Prussian carp inhabiting effluent-receiving waters (ERC) receiving municipal and sugar plant treated wastewaters, further downstream waters (DW), and a detached canal unaffected by the WWTP activities. To that end, general fish health status was determined, including plasma biochemical, haematological, oxidative stress and tissue histopathological indices, over three seasons. The greatest tissue alterations were in fall in ERC during sugar beet processing, as hypertrophy of gill epithelial and interlamellar cells, necrosis and lymphocytic infiltration, hyperplasia and hypertrophy of renal tubules, distention of hepatic sinusoids...
November 2016: Environmental Pollution
A Samuelsson, J M Pombo, C W Coen, C Mallard, P Gressens, L Poston
OBJECTIVE: Mounting evidence suggests that an overactive immune response during pregnancy may alter the development of the central nervous system in the foetus. An increased concentration of pro-inflammatory cytokines has been demonstrated in amniotic fluid of obese pregnancy. This study investigate if low-chronic inflammation, during brain development may have enduring effects on hypothalamic immune response leading to autonomic disturbances and sympathetic mediated hypertension arising from maternal obesity...
September 2016: Journal of Hypertension
Marisa K Joubert, Meghana Deshpande, Jane Yang, Helen Reynolds, Christine Bryson, Mark Fogg, Matthew P Baker, Jonathan Herskovitz, Theresa J Goletz, Lei Zhou, Michael Moxness, Gregory C Flynn, Linda O Narhi, Vibha Jawa
An In Vitro Comparative Immunogenicity Assessment (IVCIA) assay was evaluated as a tool for predicting the potential relative immunogenicity of biotherapeutic attributes. Peripheral blood mononuclear cells from up to 50 healthy naïve human donors were monitored up to 8 days for T-cell proliferation, the number of IL-2 or IFN-γ secreting cells, and the concentration of a panel of secreted cytokines. The response in the assay to 10 monoclonal antibodies was found to be in agreement with the clinical immunogenicity, suggesting that the assay might be applied to immunogenicity risk assessment of antibody biotherapeutic attributes...
2016: PloS One
Naglaa F Agamia, Tamer Abou Youssif, Abeer El-Hadidy, Amr El-Abd
OBJECTIVE: To evaluate the incidence of benign prostatic hyperplasia (BPH) and metabolic syndrome in patients with androgenetic alopecia (AGA) in comparison with those with no AGA, as several previous studies have reported inconsistent results of an association between metabolic syndrome and BPH with AGA. PATIENTS SUBJECTS AND METHODS: This cross-sectional study included 400 participants, divided into 300 patients diagnosed with AGA, with different grades according to Norwood-Hamilton classification, and 100 control subjects with no AGA...
June 2016: Arab Journal of Urology
Jiang Li, Pankaj Koinkar, Yusuke Fuchiwaki, Mikito Yasuzawa
A low invasive type glucose sensor, which has a sensing region at the tip of a fine pointed electrode, was developed for continuous glucose monitoring. Platinum-iridium alloy electrode with a surface area of 0.045mm(2) was settled at the middle of pointed PEEK (Polyetheretherketone) tubing and was employed as sensing electrode. Electrodeposition of glucose oxidase in the presence of surfactant, Triton X-100, was performed for high-density enzyme immobilization followed by the electropolymerization of o-phenylenediamine for the formation of functional entrapping and permselective polymer membrane...
December 15, 2016: Biosensors & Bioelectronics
Claudia Koch, Fabian J Eber, Carlos Azucena, Alexander Förste, Stefan Walheim, Thomas Schimmel, Alexander M Bittner, Holger Jeske, Hartmut Gliemann, Sabine Eiben, Fania C Geiger, Christina Wege
The rod-shaped nanoparticles of the widespread plant pathogen tobacco mosaic virus (TMV) have been a matter of intense debates and cutting-edge research for more than a hundred years. During the late 19th century, their behavior in filtration tests applied to the agent causing the 'plant mosaic disease' eventually led to the discrimination of viruses from bacteria. Thereafter, they promoted the development of biophysical cornerstone techniques such as electron microscopy and ultracentrifugation. Since the 1950s, the robust, helically arranged nucleoprotein complexes consisting of a single RNA and more than 2100 identical coat protein subunits have enabled molecular studies which have pioneered the understanding of viral replication and self-assembly, and elucidated major aspects of virus-host interplay, which can lead to agronomically relevant diseases...
2016: Beilstein Journal of Nanotechnology
Yongxu Mu, Zhiming Hao, Junfeng He, Ruiqiang Yan, Haiyan Liu, Lei Zhang, Heming Liu, Xiaoyan Hu, Qiming Li
Exogenous insulin and EGFP genes were transduced into bone marrow mesenchymal stem cells of beagle dogs using the retroviral vector pMSCV to prepare β-like cells. These cells were autotransplanted into the liver of diabetic dogs through hepatic arterial intervention, and physiological indices before and after transplantation were monitored. Autotransplantation of β-like cells significantly improved blood sugar, insulin levels, and body mass of diabetic dogs (P < 0.01) continuously for over 80 weeks. Since the liver function remained normal and no tumors formed, this method was determined to be reliable and safe...
August 2016: Artificial Cells, Nanomedicine, and Biotechnology
Nathalie Charrière, Cathriona Loonam, Jean-Pierre Montani, Abdul G Dulloo, Erik K Grasser
PURPOSE: There is increasing interest into the potentially beneficial effects of galactose for obesity and type 2 diabetes management as it is a low-glycemic sugar reported to increase satiety and fat mobilization. However, fructose is also a low-glycemic sugar but with greater blood pressure elevation effects than after glucose ingestion. Therefore, we investigated here the extent to which the ingestion of galactose, compared to glucose and fructose, impacts upon haemodynamics and blood pressure...
June 21, 2016: European Journal of Nutrition
Ana Maria da Silva Sousa, Daine Fiuza, Fernanda Cristina Ferreira Mikami, Karen Cristine Abrão, Rossana Pulcineli Vieira Francisco, Marcelo Zugaib
OBJECTIVE: To evaluate the retention of information after participation in multidisciplinary group in patients with gestational diabetes mellitus (GDM) through a phone contact. METHOD: 122 pregnant women diagnosed with gestational diabetes were included. After diagnosis of gestational diabetes, the patients were referred to the multidisciplinary group where they received medical, nutrition and nursing guidelines related to the disease. After three days these patients received one telephone call from a nurse, who made the same questions regarding the information received...
May 2016: Revista da Associação Médica Brasileira
A Steinert, M Haesner, E Steinhagen-Thiessen
BACKGROUND: The success of self-monitoring in the treatment of type 2 diabetes mellitus has already been verified in several studies. To date there are a multitude of smartphone apps which support diabetic patients in systematically recording and analyzing relevant health data; however, most of these smartphone apps are primarily developed for a young target group. OBJECTIVE: As part of this study we examined to what extent a smartphone app for self-monitoring is used by older diabetic patients...
June 9, 2016: Zeitschrift Für Gerontologie und Geriatrie
Christopher J Clewett, Phillip Langley, Anthony D Bateson, Aziz Asghar, Antony J Wilkinson
AIMS: Hypoglycaemia unawareness is a common condition associated with increased risk of severe hypoglycaemia. The purpose of the authors' study was to develop a simple to use, home-based and non-invasive hypoglycaemia warning system based on electroencephalography (EEG), and to demonstrate its use in a single-case feasibility study. METHODS: A participant with type 1 diabetes forms a single-person case study where blood sugar levels and EEG were recorded. EEG was recorded using skin surface electrodes placed behind the ear located within the T3 region by the participant in the home...
March 2016: Healthcare Technology Letters
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