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Exenteration pelvic surgery

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https://www.readbyqxmd.com/read/28529192/short-and-long-term-outcomes-following-pelvic-exenteration-for-gynae-oncological-and-colorectal-cancers-a-9-year-consecutive-single-centre-cohort-study
#1
Mark Katory, Ross McLean, Edgar Paez, Ali Kucukmetin, Raj Naik
OBJECTIVES: Radical pelvic exenteration can be undertaken for locally invasive or recurrent disease in both colorectal and gynaecological malignancies. In the UK this procedure is usually undertaken by the respective surgical specialties who have undergone divergent surgical training. This study describes and compares outcomes between colorectal and gynae-oncological teams following pelvic exenteration for primary and recurrent gynaecological and colorectal cancers in a single-centre multi-disciplinary team...
May 18, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28528932/robot-assisted-gynaecological-cancer-surgery-complications-and-prevention
#2
REVIEW
Ka Yu Tse, Hextan Yuen Sheung Ngan, Peter Christopher Lim
Ever since the US Food and Drug Administration approval of the use of da Vinci surgical systems (Intuitive Surgical Inc., Sunnyvale, California) in gynaecology in 2005, robot-assisted surgery has been widely adopted in different countries. Some of the applications in benign and oncological gynaecology include myomectomy, sacrocolpopexy, tubal anastomosis, simple hysterectomy, radical hysterectomy, radical trachelectomy, pelvic and/or para-aortic lymphadenectomy and even debulking surgery for ovarian cancer and pelvic exenteration for recurrent cervical and vaginal cancer...
April 23, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28498727/good-prognosis-went-badly-fulminant-evolution-of-a-29-year-old-patient-with-verrucous-carcinoma-of-the-cervix
#3
Rodica M Anghel, Oana G Trifanescu, Radu I Mitrica, Fabiana G Curea, Inga Botnariuc, Catalin G Herghelegiu, Cristina M Orlov, Silvia M Ilie
Verrucous carcinoma (VC) is a very rare variant of squamous cell carcinoma of the cervix, difficult to point out in histology because of its benign appearance. We present the case of a 29-year-old woman with a locally advanced cervical VC who underwent radiotherapy followed by radical hysterectomy. After local relapse and despite pelvic exenteration, her condition deteriorated. Treatment of choice in VC is surgery, because of the risk of anaplastic transformation under irradiation, raising the chances of distant spread and converting this rather benign-like type of cancer to an aggressive cancer...
May 12, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28498240/simple-vaginal-trachelectomy-a-valuable-fertility-preserving-option-in-early-stage-cervical-cancer
#4
Marie Plante, Marie-Claude Renaud, Alexandra Sebastianelli, Jean Gregoire
OBJECTIVE: Radical trachelectomy is a valid alternative for the treatment of early-stage cervical cancer in young women who wish to preserve fertility potential. Recent data indicate that even less radical surgery could be performed in low-risk cases. The objective of our study was to evaluate the safety of simple vaginal trachelectomy and node assessment in patients with low-risk, early-stage cervical cancer (<2 cm). METHODS: From May 2007 to July 2016, 35 women underwent a simple vaginal trachelectomy with laparoscopic sentinel lymph node mapping + pelvic node dissection...
June 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28255734/robot-assisted-laparoscopic-transperitoneal-infrarenal-lymphadenectomy-in-patients-with-locally-advanced-cervical-cancer-by-single-docking-do-we-need-a-backup-procedure
#5
Fatih Gucer, Selim Misirlioglu, Nuri Ceydeli, Cagatay Taskiran
To present our initial experience on the feasibility of robotic transperitoneal para-aortic lymphadenectomy up to left renal vein via single docking approach by high port insertion technique followed by left shoulder docking as a rescue backup procedure in surgically obstructed patients undergoing surgical staging because of locally advanced cervical cancer (LACC). Prospective observational preliminary study. Canadian Task Force classification II-3. Tertiary-care academic affiliated private hospital. Ten patients with LACC who underwent robotic transperitoneal infrarenal para-aortic lymphadenectomy between January 2012 and December 2014...
March 2, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28133349/-long-term-survival-of-a-patient-with-sigmoid-colon-cancer-with-multiple-visceral-metastases
#6
Yoshiyuki Sasaki, Naoto Nishigori, Fumikazu Koyama, Takeshi Ueda, Takashi Inoue, Keijirou Kawasaki, Shinsaku Obara, Takayuki Nakamoto, Yasuyuki Nakamura, Hisao Fujii, Yoshiyuki Nakajima
A 66-year-old woman underwent total pelvic exenteration for a pelvic tumor. The pathological diagnosis was sigmoid colon cancer T4b(in the small intestine, uterus, and vagina), N0, M0, Stage II . The patient was treated with XELOX for 6 months as adjuvant chemotherapy and was then treated with IRIS for another 6 months. Brain metastasis developed in the left occipital lobe after 12 months, and she underwent craniotomy and enucleation of the tumor. Liver metastasis and peritoneal dissemination metastasis developed 16 months after her initial diagnosis...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28130592/extended-lymphadenectomy-for-locally-advanced-and-recurrent-rectal-cancer
#7
Panagiotis A Georgiou, S Mohammed Ali, Gina Brown, Shahnawaz Rasheed, Paris P Tekkis
PURPOSE: The purpose of this study is to assess the value of extended (lateral) lymphadenectomy (EL) in the operative management of locally advanced and recurrent rectal cancer. METHODS: Patients that underwent exenterative surgery for locally advanced or recurrent rectal cancer between 2006 and 2009 were included in the study. A decision for EL was taken at the local multidisciplinary meeting based on the radiological findings. Perioperative and oncological outcomes were assessed and compared between the EL and non-EL group prospectively...
March 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28108013/detection-of-extra-regional-tumour-recurrence-with-18-f-fdg-pet-ct-in-patients-with-recurrent-gynaecological-malignancies-being-considered-for-radical-salvage-surgery
#8
H Brar, T May, N Tau, D Langer, P MacCrostie, K Han, U Metser
AIM: To compare the detection rate of extra-regional metastases in patients with recurrent gynaecological malignancies being considered for radical salvage surgery with combined 2-[(18)F]-fluoro-2-deoxy-d-glucose ((18)F-FDG) positron-emission tomography (PET)/computed tomography (CT) compared to conventional imaging. MATERIALS AND METHODS: A retrospective review was performed of all patients in a provincial database with recurrent gynaecological malignancies being considered for pelvic exenteration that underwent restaging with CT/PET between March 2011 and October 2014...
April 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28106653/outcomes-of-rectovaginal-fistula-repair
#9
Jenifer N Byrnes, Jennifer J Schmitt, Benjamin M Faustich, Kristin C Mara, Amy L Weaver, Heidi K Chua, John A Occhino
OBJECTIVES: Rectovaginal fistulae (RVF) often represent surgical challenges, and treatment must be individualized. We describe outcomes after primary surgical repair stratified by fistula etiology and surgical approach. METHODS: This retrospective cohort study included women who underwent surgical management of RVF at a tertiary care center between July 1, 2001 and December 31, 2013. Cases were stratified according to the following etiology: cancer (RVF-C), inflammatory bowel disease or infectious (RVF-I), and other (RVF-O)...
March 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28095995/pelvic-floor-reconstruction-by-modified-rectus-abdominis-myoperitoneal-mram-flap-after-pelvic-exenterations
#10
D Cibula, M Zikan, D Fischerova, R Kocian, A Germanova, A Burgetova, L Dusek, Z Fartáková, M Schneiderová, K Nemejcová, J Slama
OBJECTIVE: To describe the technique and report experiences with pelvic floor reconstruction by modified rectus abdominis myoperitoneal (MRAM) flap after extensive pelvic procedures. METHODS: Surgical technique of MRAM harvest and transposition is carefully described. The patients in whom pelvic floor reconstruction with MRAM after either infralevator pelvic exenteration and/or extended lateral pelvic sidewall excision was carried out were enrolled into the study (MRAM group, n=16)...
March 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28078119/surgical-outcomes-of-post-chemoradiotherapy-unresectable-locally-advanced-rectal-cancers-improve-with-interim-chemotherapy-is-folfirinox-better-than-capox
#11
Vikas Ostwal, Reena Engineer, Anant Ramaswamy, Arvind Sahu, Saurabh Zanwar, Suprita Arya, Supriya Chopra, Munita Bal, Prachi Patil, Ashwin Desouza, Avanish Saklani
BACKGROUND: Role of chemotherapy in patients who continue to have unresectable disease after pre-operative chemo-radiotherapy (CRT) remains largely unaddressed. METHODS: Patients with LA rectal cancer from January 2013 to June 2015 were evaluated. Post-CRT, patients, who were deemed unresectable, were considered for further interim chemotherapy (i-CT). RESULTS: Seventy six patients (15%) with median age of 38.5 years received i-CT after CRT...
December 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28070552/long-term-survival-after-anterior-pelvic-exenteration-and-total-vaginectomy-for-recurrent-endometrial-carcinoma-with-metastatic-inguinal-nodes-at-the-time-of-surgery
#12
Benjamin Margolis, Sun Woo Kim, Dennis S Chi
•Pelvic exenteration can be used in patients with multifocal recurrence.•Ability to achieve negative margins remains a necessity for pelvic exenteration.•Individualized treatments are essential for those with recurrent malignancy.
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28027809/-laparoscopic-anterior-pelvic-exenteration-in-a-patient-with-locally-advanced-melanoma
#13
David Isla-Ortiz, Gonzalo Montalvo-Esquivel, Roberto Eduardo Herrera-Goepfert, Ángel Herrera-Gómez, Rosa Angélica Salcedo-Hernández
BACKGROUND: Pelvic exenteration is one of the most mutilating surgical procedures with high post-operative morbidity. The laparoscopic technique aims to reduce perioperative complications and reduce post-surgical recovery. OBJECTIVE: We present the first case of laparoscopic anterior exenteration for locally advanced melanoma, held at the National Cancer Institute and published in Mexico. CASE REPORT: Patient 60 years of age diagnosed with invasive vulvar melanoma with bladder extension upon whom laparoscopic anterior pelvic exenteration with external urinary reconstruction was performed...
December 24, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/27990753/triangle-of-marcille-the-anatomical-gateway-to-lateral-pelvic-exenteration
#14
Peter Lee, Katherine E Francis, Michael J Solomon, George Ramsey-Stewart, Kirk K S Austin, Cherry Koh
BACKGROUND: To perform more radical surgery for complex pelvic malignancies and recurrent colorectal cancer, the surgeon must increasingly operate outside the conventional anatomical planes. Published in 1963 the 'Triangle of Marcille' (lumbosacral triangle) remained primarily of intellectual interest being found lateral to the traditional operating field. However, with the advancement of complex colorectal and gynaecological surgery it now provides a schema to assist surgeons in becoming acquainted with a complex and poorly understood anatomical region...
December 18, 2016: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/27957822/laparoscopic-assisted-abdominoperineal-resection-combined-with-en-bloc-prostatectomy-using-the-trans-sacral-approach-for-locally-invasive-rectal-cancer-a-case-report
#15
Jo Tashiro, Shigeki Yamaguchi, Toshimasa Ishii, Hiroka Kondo, Kiyoka Hara
Laparoscopic-assisted abdominoperineal resection and en-bloc prostatectomy using the trans-sacral approach for locally invasive rectal cancer that invades only the prostate is useful in order to avoid total pelvic exenteration. The patient was a 63-year-old man with cT4b (prostate) N1M0, stage IIIC rectal cancer. Curative resection was performed. Histopathological findings did not indicate definitive invasion into the prostate gland. The patient was discharged from the hospital on postoperative day 32 with an anastomotic leak and a ureteral catheter...
December 13, 2016: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/27760707/survival-after-pelvic-exenteration-for-uterine-malignancy-a-national-cancer-data-base-study
#16
Brandon-Luke L Seagle, Megan Dayno, Anna E Strohl, Stephen Graves, Wilberto Nieves-Neira, Shohreh Shahabi
OBJECTIVE: To determine overall survival (OS) and factors associated with OS after pelvic exenteration for uterine cancer. METHODS: Women with uterine cancer who underwent exenteration (n=1160) were identified from the 1998-2011 National Cancer Data Base. Kaplan-Meier and multivariate Cox proportional-hazards survival analyses were performed to test for associations of potential explanatory variables with OS. Analyzed confounders included age, comorbidity score, insurance status, income, distance from home to treatment center, stage, distant and nodal metastasis, tumor size, surgical margin status, exenteration type, and treatment with radiation and/or chemotherapy...
December 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27749474/palliative-pelvic-exenteration-clinical-outcomes-and-quality-of-life
#17
Aaron J Quyn, Michael J Solomon, Peter M Lee, Tim Badgery-Parker, Lindy M Masya, Jane M Young
BACKGROUND: Locally advanced pelvic malignancy can be associated with disabling symptoms and reduced quality of life. If resectable with clear margins, a pelvic exenteration can offer long-term survival and improved quality of life. Its role in the palliation of symptoms has been described; however, the clinical outcomes and surgical indication are poorly defined. OBJECTIVE: This study describes the clinical and quality-of-life outcomes after palliative pelvic exenteration for advanced pelvic malignancy...
November 2016: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27689067/cytoreductive-surgery-for-men-with-metastatic-prostate-cancer
#18
Nikolas Katelaris, Declan Murphy, Nathan Lawrentschuk, Athos Katelaris, Daniel Moon
BACKGROUND: Cytoreductive surgery for metastatic prostate cancer is an emerging area of interest with a potential upside that includes local control, delayed initiation of hormone therapy, and possibly improved cancer specific survival. In order for radical prostatectomy to be an effective treatment option for men in this group, the benefits must outweigh the surgical morbidity. The aim of this study was to present a case series and assess the literature feasibility of cytoreductive surgery for men with metastatic prostate cancer...
September 2016: Prostate International
https://www.readbyqxmd.com/read/27678502/effects-of-neoadjuvant-chemotherapy-plus-radical-surgery-as-front-line-treatment-strategy-in-patients-affected-by-figo-stage-iii-cervical-cancer
#19
Violante Di Donato, Michele Carlo Schiavi, Ilary Ruscito, Virginia Sibilla Visentin, Innocenza Palaia, Claudia Marchetti, Margherita Fischetti, Marco Monti, Ludovico Muzii, Pierluigi Benedetti Panici
BACKGROUND: To assess the clinical efficacy and prognostic outcome of neoadjuvant chemotherapy (NACT) plus radical surgery (RS) as front line treatment in patients with FIGO stage III cervical cancer (CC). METHODS: In this retrospective study, 52 FIGO stage III CC patients treated from 2005 to 2015 were included. All patients received platinum-based chemotherapy. Patients reporting clinical response or stable disease after NACT underwent to RS and bilateral systematic pelvic lymphadenectomy with or without aortic lymphadenectomy or anterior exenteration...
December 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27614445/state-of-the-art-treatment-and-novel-agents-in-local-and-distant-recurrences-of-cervical-cancer
#20
REVIEW
Clemens B Tempfer, Matthias W Beckmann
Depending on the stage at initial presentation, cervical cancer will recur in 25-61% of women. Typical manifestations of recurrent cervical cancer include the central pelvis and the pelvic side walls as well as retroperitoneal lymph node basins in the pelvis and the para-aortic region, and - more rarely - supraclavicular lymph nodes. There are no typical symptoms of recurrent cervical cancer. Women with suspected recurrence after cervical cancer based on gynecological examination or organ-specific symptoms must undergo imaging studies and - if technically feasible - biopsy with histological verification, especially in cases of distant metastases, in order to rule out a second primary...
2016: Oncology Research and Treatment
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