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Sleep disorders and cognitive

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https://www.readbyqxmd.com/read/28436681/psychometric-validation-of-the-geriatric-suicide-ideation-scale-gsis-among-older-adults-with-bipolar-disorder
#1
Norm O'Rourke, Marnin J Heisel, Sarah L Canham, Andrew Sixsmith, Hamed Yaghoubi-Shahir, David B King
OBJECTIVES: Across age groups, bipolar disorder (BD) carries the greatest risk of death by suicide of all psychiatric conditions; 25%-50% of those with BD will make one or more suicide attempt. Psychometrically sound instruments are required to reliably measure suicide ideation and risk of self-harm for older adults with BD. For this study, we validate the geriatric suicide ideation scale (GSIS) with adults 50+ years with BD. METHODS: We recruited a global sample of 220 older adults with BD (M = 58...
April 24, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28434429/association-between-sleep-disordered-breathing-and-nighttime-driving-performance-in-mild-cognitive-impairment
#2
Nathan Cross, Zoe Terpening, Shantel L Duffy, Simon J G Lewis, Ron Grunstein, Keith Wong, Sharon L Naismith
OBJECTIVES: The effect of sleep disordered breathing (SDB) on driving performance in older adults has not been extensively investigated, especially in those with mild cognitive impairment (MCI). The aim of this study was to examine the relationship between severity measures of SDB and a simulated driving task in older adults with and without MCI. METHODS: Nineteen older adults (age ≥50) meeting criteria for MCI and 23 age-matched cognitively intact controls underwent neuropsychological assessment and a driving simulator task in the evening before a diagnostic sleep study...
April 24, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28431424/sleep-disordered-breathing-postoperative-delirium-and-cognitive-impairment
#3
Enoch W K Lam, Frances Chung, Jean Wong
Sleep-disordered breathing (SDB) is highly prevalent in the general population and has been associated with cognitive impairment in older individuals. Delirium is an acute decline in cognitive function and attention that often occurs after surgery, especially in older individuals. Several recent studies suggest an association between SDB and postoperative delirium. The aim of this systematic review is to examine the current literature on SDB, postoperative delirium, and cognitive impairment and to discuss the pathophysiology and perioperative considerations...
May 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28431177/altered-functional-connectivity-in-idiopathic-rapid-eye-movement-sleep-behavior-disorder-a-resting-state-eeg-study
#4
Jun-Sang Sunwoo, Sanghun Lee, Jung-Hoon Kim, Jung-Ah Lim, Tae-Joon Kim, Jung-Ick Byun, Min Hee Jeong, Kwang Su Cha, Jeong Woo Choi, Kyung Hwan Kim, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Kon Chu, Manho Kim, Sang Kun Lee, Ki-Young Jung
Study Objectives: Idiopathic rapid eye movement sleep behavior disorder (iRBD) is considered as a prodromal stage of synucleinopathy. Although loss of functional connectivity is implicated in neurodegenerative diseases, network characteristics of electroencephalography (EEG) in iRBD are unknown. Therefore, we evaluated resting-state EEG functional connectivity to identify the brain network changes in patients with iRBD. Methods: We prospectively enrolled 20 patients with polysomnography-confirmed iRBD and 16 control subjects...
April 18, 2017: Sleep
https://www.readbyqxmd.com/read/28422847/correlation-between-calpain-10-single-nucleotide-polymorphisms-and-obstructive-sleep-apnea-hypopnoea-syndrome-with-ischemic-stroke-in-a-chinese-population-a-population-based-study
#5
Wei Zhang, Zhi-Ru Zhao, Chang-Fei Dai, Rong Zhang, Jie Chen, Hui-Juan Tian, Yun-Long Wang, Ji-Hong Sun, Qiu-Fang Lian
BACKGROUND: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common chronic disorder which is followed by various complications. Calpain-10 belongs to a commonly expressed member of the Calpain-like cysteine protease family, which acts as risk marker for some diseases. The purpose of this study is to elucidate correlation between Calpain-10 single-nucleotide polymorphisms (SNPs) and the incidence of OSAHS followed by ischemic stroke (IS). METHODS: OSAHS patients were divided as OSAHS + IS, OSAHS, and control groups, respectively...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28419607/subjective-and-objective-sleep-quality-modulate-emotion-regulatory-brain-function-in-anxiety-and-depression
#6
Heide Klumpp, Julia Roberts, Mary C Kapella, Amy E Kennedy, Anand Kumar, K Luan Phan
BACKGROUND: Disturbances in emotion regulation and sleep are shared across anxiety and mood disorders. Poor sleep has been shown to impair cognitive processes which may undermine cognitive regulatory function. However, it remains unknown if sleep quality impacts regulatory mechanisms in clinical anxiety and depression. METHODS: During fMRI, 78 patients with social anxiety disorder, generalized anxiety disorder, and/or major depressive disorder completed a validated emotion regulation task, which involved reappraisal (i...
April 18, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28415870/longitudinal-changes-in-the-antecedent-and-early-manifest-course-of-bipolar-disorder-a-narrative-review-of-prospective-studies
#7
Andrea Pfennig, Karolina Leopold, Philipp Ritter, Anne Böhme, Emanuel Severus, Michael Bauer
OBJECTIVE: Prospective study designs ideally allow patients to be followed from the first manifestations of the illness or even from an at-risk stage. It can thus provide data on the predictive value of changes in clinical symptomatology, cognition or further biological markers to broaden our understanding of the etiopathology and symptomatic trajectory of bipolar disorders. The scope of this narrative review is to summarize evidence from prospectively collected data on psychopathological and other clinical and biological changes in the early developmental course of bipolar disorders...
May 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28410662/lewy-body-disorders
#8
REVIEW
Douglas Galasko
Dementia syndromes associated with Lewy bodies are subdivided into dementia with Lewy bodies (DLB), an underdiagnosed cause of dementia in the elderly, and Parkinson disease with dementia (PDD), cognitive impairment appearing in people diagnosed with Parkinson disease. Their neuropathologic substrates are the widespread distribution of aggregates of the protein α-synuclein in neurons in cortical brain regions, accompanied by variable Alzheimer pathology. Clinical features of DLB and PDD include distinctive changes in cognition, behavior, movement, sleep, and autonomic function...
May 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/28404803/neuropsychiatric-symptoms-predict-hypometabolism-in-preclinical-alzheimer-disease
#9
Kok Pin Ng, Tharick A Pascoal, Sulantha Mathotaarachchi, Chang-Oh Chung, Andréa L Benedet, Monica Shin, Min Su Kang, Xiaofeng Li, Maowen Ba, Nagaendran Kandiah, Pedro Rosa-Neto, Serge Gauthier
OBJECTIVE: To identify regional brain metabolic dysfunctions associated with neuropsychiatric symptoms (NPS) in preclinical Alzheimer disease (AD). METHODS: We stratified 115 cognitively normal individuals into preclinical AD (both amyloid and tau pathologies present), asymptomatic at risk for AD (either amyloid or tau pathology present), or healthy controls (no amyloid or tau pathology present) using [(18)F]florbetapir PET and CSF phosphorylated tau biomarkers...
April 12, 2017: Neurology
https://www.readbyqxmd.com/read/28400355/mobile-phone-delivered-cognitive-behavioral-therapy-for-insomnia-a-randomized-waitlist-controlled-trial
#10
Corine Hg Horsch, Jaap Lancee, Fiemke Griffioen-Both, Sandor Spruit, Siska Fitrianie, Mark A Neerincx, Robbert Jan Beun, Willem-Paul Brinkman
BACKGROUND: This study is one of the first randomized controlled trials investigating cognitive behavioral therapy for insomnia (CBT-I) delivered by a fully automated mobile phone app. Such an app can potentially increase the accessibility of insomnia treatment for the 10% of people who have insomnia. OBJECTIVE: The objective of our study was to investigate the efficacy of CBT-I delivered via the Sleepcare mobile phone app, compared with a waitlist control group, in a randomized controlled trial...
April 11, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28399097/-influence-chronopharmacology-therapy-methionine-melaxen-on-the-dynamics-of-sleep-disturbance-cognitive-and-emotional-disorders-brain-derived-neurotrophic-factor-bdnf-in-patients-with-cerebral-stroke-in-the-early-and-late-recovery-periods
#11
E V Kostenko
AIM: To study the efficacy of melaxen on the dynamics of sleep disturbance, cognitive and emotional disorders, BDNF and the level of secretion of melatonin (6-SOMT) in patients with stroke in the early and late recovery phase. MATERIAL AND METHODS: One hundred and ten patients in the rehabilitation period of stroke (mean age of 58.4±6.4 years), including 60 patients in the early recovery phase (group 1) and 50 patients in the late phase (group 2), were studied...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28398338/the-histamine-h3-receptor-antagonist-thioperamide-rescues-circadian-rhythm-and-memory-function-in-experimental-parkinsonism
#12
D Masini, C Lopes-Aguiar, A Bonito-Oliva, D Papadia, R Andersson, A Fisahn, G Fisone
Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by motor impairment and a wide range of non-motor symptoms, including sleep disorders and cognitive and affective deficits. In this study, we used a mouse model of PD based on 6-hydroxydopamine (6-OHDA) to examine the effect of thioperamide, a histamine H3 receptor antagonist, on circadian activity, recognition memory and anxiety. A partial, bilateral 6-OHDA lesion of the striatum reduces motor activity during the active phase of the 24 h cycle...
April 11, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28397310/creatine-supplementation-reduces-sleep-need-and-homeostatic-sleep-pressure-in-rats
#13
Markus Dworak, Tae Kim, Robert W Mccarley, Radhika Basheer
Sleep has been postulated to promote brain energy restoration. It is as yet unknown if increasing the energy availability within the brain reduces sleep need. The guanidine amino acid creatine (Cr) is a well-known energy booster in cellular energy homeostasis. Oral Cr-monohydrate supplementation (CS) increases exercise performance and has been shown to have substantial effects on cognitive performance, neuroprotection and circadian rhythms. The effect of CS on cellular high-energy molecules and sleep-wake behaviour is unclear...
April 11, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28395207/brief-cognitive-behavioral-therapy-for-insomnia-delivered-to-depressed-veterans-receiving-primary-care-services-a-pilot-study
#14
Wilfred R Pigeon, Jennifer Funderburk, Todd M Bishop, Hugh F Crean
BACKGROUND: Depression and insomnia are treatable, often co-occur and are common among primary care patients. Treatments designed for primary care must be brief, effective and ideally have the potential to address multiple symptoms. A brief form of cognitive behavioral therapy for insomnia (CBT-I) was piloted among depressed primary care patients with insomnia some of whom endorsed suicidal ideation. METHODS: Veterans Affairs primary care patients were randomized to either CBT-I or sleep hygiene...
April 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28394172/sleep-the-night-before-and-after-a-treatment-session-a-critical-ingredient-for-treatment-adherence
#15
Michael R Dolsen, Adriane M Soehner, Charles M Morin, Lynda Bélanger, Matthew Walker, Allison G Harvey
OBJECTIVE: Sleep prepares key neural structures for next-day learning, and sleep obtained after learning promotes subsequent memory consolidation supporting long-term retention. This study examined whether sleep the night before and after a therapy session predicts aspects of treatment adherence. METHOD: As part of a randomized clinical trial, 188 adults (62.7% female, mean age = 47.5, 80.5% Caucasian) with persistent insomnia received cognitive-behavioral therapy for insomnia...
April 10, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28392168/cognitive-and-behavioral-therapies-in-the-treatment-of-insomnia-a-meta-analysis
#16
REVIEW
Annemieke van Straten, Tanja van der Zweerde, Annet Kleiboer, Pim Cuijpers, Charles M Morin, Jaap Lancee
Insomnia is a major public health problem considering its high prevalence, impact on daily life, co-morbidity with other disorders and societal costs. Cognitive behavioral treatment for insomnia (CBTI) is currently considered to be the preferred treatment. However, no meta-analysis exists of all studies using at least one component of CBTI for insomnia, which also uses modern techniques to pool data and to analyze subgroups of patients. We included 87 randomized controlled trials, comparing 118 treatments (3724 patients) to non-treated controls (2579 patients)...
February 9, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28390440/prevalence-of-and-risk-factors-for-minor-and-major-depression-among-community-dwelling-older-adults-in-taiwan
#17
Chi-Shin Wu, Shu-Han Yu, Chun-Yi Lee, Han-Yun Tseng, Yen-Feng Chiu, Chao Agnes Hsiung
BACKGROUND: This study was conducted to estimate prevalence rates and risk factors for late-life depression in a large nationwide representative sample from Taiwan. METHODS: A total of 5,664, randomly sampled individuals aged ≥55 years were enrolled. Clinically, relevant depressive symptoms were classified using the Center for Epidemiological Studies Depression Scale (CES-D score ≥16), and major depression was confirmed using the Primary Care Evaluation of Mental Disorders...
April 9, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28384694/auditory-phenotype-of-smith-magenis-syndrome
#18
Megan A Brendal, Kelly A King, Christopher K Zalewski, Brenda M Finucane, Wendy Introne, Carmen C Brewer, Ann C M Smith
Purpose: The purpose of this study was to describe the auditory phenotype of a large cohort with Smith-Magenis syndrome (SMS), a rare disorder including physical anomalies, cognitive deficits, sleep disturbances, and a distinct behavioral phenotype. Method: Hearing-related data were collected for 133 individuals with SMS aged 1-49 years. Audiogram data (97 participants) were used for cross-sectional and longitudinal analyses. Caregivers completed a sound sensitivity survey for 98 individuals with SMS and a control group of 24 unaffected siblings...
April 4, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28381508/clinical-manifestations-of-the-anti-iglon5-disease
#19
Carles Gaig, Francesc Graus, Yarko Compta, Birgit Högl, Luis Bataller, Norbert Brüggemann, Caroline Giordana, Anna Heidbreder, Katya Kotschet, Jan Lewerenz, Stefan Macher, Maria J Martí, Teresa Montojo, Jesus Pérez-Pérez, Inmaculada Puertas, Caspar Seitz, Mateus Simabukuro, Nieves Téllez, Klaus-Peter Wandinger, Alex Iranzo, Guadalupe Ercilla, Lidia Sabater, Joan Santamaría, Josep Dalmau
OBJECTIVE: To report the presentation, main syndromes, human leukocyte antigen (HLA) association, and immunoglobulin G (IgG) subclass in the anti-IgLON5 disease: a disorder with parasomnias, sleep apnea, and IgLON5 antibodies. METHODS: This was a retrospective clinical analysis of 22 patients. The IgG subclass was determined using reported techniques. RESULTS: Patients' median age was 64 years (range 46-83). Symptoms that led to initial consultation included sleep problems (8 patients; 36%), gait abnormalities (8; 36%), bulbar dysfunction (3; 14%), chorea (2; 9%), and cognitive decline (1; 5%)...
April 5, 2017: Neurology
https://www.readbyqxmd.com/read/28375912/disorders-of-taste-and-smell
#20
Ronald DeVere
PURPOSE OF REVIEW: This article aims to educate clinical neurologists on the importance of taste and smell disorders in clinical neurology. These disorders commonly occur in head trauma, multiple sclerosis, seizure disorders, and neurodegenerative diseases such as idiopathic Parkinson disease and dementia, mild cognitive impairment, and Alzheimer disease, just to name a few. This article covers the basic anatomy of smell and taste, notes the important points of taking a proper history, and discusses smell and taste testing, which are inexpensive, minimally time-consuming procedures...
April 2017: Continuum: Lifelong Learning in Neurology
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