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https://www.readbyqxmd.com/read/27919634/a-commercial-porcine-circovirus-pcv-type-2a-based-vaccine-reduces-pcv2d-viremia-and-shedding-and-prevents-pcv2d-transmission-to-na%C3%A3-ve-pigs-under-experimental-conditions
#1
Tanja Opriessnig, Chao-Ting Xiao, Patrick G Halbur, Priscilla F Gerber, Shannon R Matzinger, Xiang-Jin Meng
Porcine circovirus type 2 (PCV2) vaccination has been effective in protecting pigs from clinical disease and today is used extensively. Recent studies in vaccinated populations indicate a major PCV2 genotype shift from the predominant PCV2 genotype 2b towards 2d. The aims of this study were to determine the ability of the commercial inactivated PCV2a vaccine Circovac® to protect pigs against experimental challenge with a 2013 PCV2d strain and prevent transmission. Thirty-eight pigs were randomly divided into four groups with 9-10 pigs per group: NEG (sham-vaccinated, sham-challenged), VAC (PCV2a-vaccinated, sham-challenged), VAC+CHAL (PCV2a-vaccinated and PCV2d-challenged), and CHAL (sham-vaccinated, PCV2d-challenged)...
December 2, 2016: Vaccine
https://www.readbyqxmd.com/read/27919526/factors-related-to-the-development-of-acquired-von-willebrand-syndrome-in-patients-with-essential-thrombocythemia-and-polycythemia-vera
#2
A Rottenstreich, G Kleinstern, S Krichevsky, D Varon, D Lavie, Y Kalish
OBJECTIVE: We characterized acquired von Willebrand syndrome (AVWS) among essential thrombocythemia (ET) and polycythemia vera (PV) patients. METHODS: A review of patients with ET or PV evaluated for AVWS. RESULTS: Of 116 patients with ET, 64 (55%) developed AVWS; of 57 with PV, 28 (49%) developed AVWS. Median platelet counts of ET and PV patients who developed AVWS were 920×10(9)/L and 679×10(9)/L, respectively (P=0.01). Of patients who developed AVWS, 69...
December 2, 2016: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/27894962/clinico-pathology-and-hemato-biochemistry-responses-in-buffaloes-infected-with-pasteurella-multocida-type-b-2-immunogen-outer-membrane-protein
#3
Eric Lim Teik Chung, Faez Firdaus Jesse Abdullah, Ali Dhiaa Marza, Wessam Monther Mohammed Saleh, Hayder Hamzah Ibrahim, Yusuf Abba, Mohd Zamri-Saad, Abd Wahid Haron, Abdul Aziz Saharee, Mohd Azmi Mohd Lila, Mohd Jefri Norsidin
The aim of this study was to investigate the clinico-pathology and haemato-biochemistry alterations in buffaloes inoculated with Pasteurella multocida type B:2 immunogen outer membrane protein via subcutaneous and oral routes. Nine buffalo heifers were divided equally into 3 treatment groups. Group 1 was inoculated orally with 10 mL of phosphate buffer saline (PBS); Group 2 and 3 were inoculated with 10 mL of outer membrane protein broth subcutaneously and orally respectively. Group 2 buffaloes showed typical haemorrhagic septicaemia clinical signs and were only able to survive for 72 h of the experiment...
November 25, 2016: Microbial Pathogenesis
https://www.readbyqxmd.com/read/27870110/the-hematology-of-captive-bobtail-lizards-tiliqua-rugosa-blood-counts-light-microscopy-cytochemistry-and-ultrastructure
#4
Cheryl A Moller, Tibor Gaál, Jennifer N Mills
INTRODUCTION: Bobtail lizards (Tiliqua rugosa) are native to Australia. The only previous study on the hematology of this species documented just 6 animals. OBJECTIVES: The aims of this study were to characterize the light microscopy, ultrastructure and cytochemistry of blood cells, and evaluate CBCs of captive Bobtail lizards. METHODS: Over 2 consecutive summers, heparinized venous blood was collected from the ventral coccygeal vein of 46 clinically healthy, captive indoor- or outdoor-housed adult Bobtails...
November 21, 2016: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/27862712/invasive-pneumococcal-infections-in-children-following-transplantation-in-the-pneumococcal-conjugate-vaccine-era
#5
Liset Olarte, Philana Ling Lin, William J Barson, Jose R Romero, Tina Q Tan, Laurence B Givner, Jill A Hoffman, John S Bradley, Kristina G Hultén, Edward O Mason, Sheldon L Kaplan
BACKGROUND: Pediatric recipients of hematopoietic stem cell and solid organ transplants are at increased risk of invasive pneumococcal infections (IPI). Data on IPI in this population is scarce. To our knowledge, this is the first study describing the epidemiology of IPI among pediatric transplant recipients in the pneumococcal conjugate vaccine (PCV) era. METHODS: We identified transplant recipients with IPI at 8 children's hospitals in the U.S. from our surveillance database (2000-2014)...
November 9, 2016: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/27852328/a-pilot-program-of-knowledge-translation-and-implementation-for-newborn-resuscitation-using-us-peace-corps-volunteers-in-rural-madagascar
#6
Kristin Close, Michele Karel, Michelle White
BACKGROUND: Prevention of adverse perinatal outcome using the Helping Babies Breathe (HBB) neonatal resuscitation algorithm can reduce perinatal mortality in low income settings. Mercy Ships is a non-governmental organisation providing free healthcare education in sub-Saharan Africa and in an attempt to reach more rural areas of Madagascar with our neonatal resuscitation training we designed a novel approach in collaboration with US Peace Corps Volunteers (PCV). PCVs work in rural areas and contribute to locally determined public health initiatives...
November 16, 2016: Globalization and Health
https://www.readbyqxmd.com/read/27843227/combined-argon-laser-photocoagulation-and-antivascular-endothelial-growth-factor-for-management-of-macular-polypoidal-choroidal-vasculopathy
#7
Parveen Sen, S Vinay Kumar, Muna Bhende, Tarun Sharma
AIM: To evaluate the efficacy of combination therapy of argon laser photocoagulation and intravitreal antivascular endothelial growth factor (VEGF) injection in idiopathic polypoidal choroidal vasculopathy (PCV) involving macula. MATERIALS AND METHODS: A retrospective interventional study involving 12 eyes of 11 patients diagnosed with PCV involving the macula on indocyanine green angiography (ICGA). Intravitreal anti-VEGF was given in eyes with significant subretinal/sub retinal pigment epithelium hemorrhage or exudation...
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27830999/the-potential-role-of-hematocrit-control-on-symptom-burden-among-polycythemia-vera-patients-insights-from-the-cyto-pv-and-mpn-saf-patient-cohorts
#8
Robyn Marie Scherber, Holly Lynn Geyer, Amylou C Dueck, Heidi E Kosiorek, Guido Finazzi, Riccardo Cavazzina, Arianna Masciulli, Marco Scarano, Alessandro M Vannucchi, Ruben A Mesa, Tiziano Barbui
Current guidelines suggest that polycythemia vera (PV) patients maintain a strict hematocrit less than 45%. However, to date, little is known about the relationship between HCT control and PV- related symptom burden. In this study, PV patient data was analyzed from the CYTO PV trial (n = 224) and the MPN-SAF study cohort (n = 645). No significant differences in symptom burden were seen at the 6 and 12 month follow-up when evaluating prospective hematocrit control in the CYTO PV cohort. Patients in the MPN-SAF cohort with a worst item score of greater than 5/10 on the Myeloproliferative Neoplasm Symptom Total Symptom Score had a significantly lower mean hematocrit (p = ...
November 10, 2016: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/27822238/efficacy-of-repeated-doses-of-diminazene-aceturate-dinazene-%C3%A2-in-the-treatment-of-experimental-trypanosoma-brucei-infection-of-albino-rats
#9
I O Ezeh, E N Ugwu, O V Enemuo, C F Obi, C N Iheagwam, R C Ezeokonkwo, D N Onah
The efficacy of repeated doses of Dinazene(®) in Albino rats experimentally infected with Trypanosoma brucei (Gboko strain) was investigated. A total of 30 adult female Albino rats weighing 130-190 g were used for the study. They were assigned to six groups (groups A-F) of five rats each. Groups A-D were infected intraperitoneally with 1.0 × 10(6) trypanosomes in 400 µL of PBS diluted blood while groups E (uninfected treated) and F (uninfected untreated) served as controls. The rats in the groups A-D as well as those in group E were treated with 7...
2016: Iranian journal of veterinary research
https://www.readbyqxmd.com/read/27819116/safety-and-immunogenicity-of-pneumococcal-conjugate-vaccine-in-preterm-infants-a-meta-analysis
#10
Kai Duan, Jin Guo, Ping Lei
OBJECTIVE: To assess the safety and immunogenicity of pneumococcal conjugate vaccine (PCVs) in preterm infants. METHODS: In accordance with the PRISM (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement (as of May 2015), a meta-analysis was conducted to evaluate the safety and immunogenicity of PCVs in preterm infants. RESULTS: Ten thousand nine hundred sixty full-term infants and 2131 preterm infants with 344 preterm infants of <2500 g birth weight [low-birth weight (LBW)] were included, and all the subjects were immunized with either PCV-7, PCV-10 or PCV-13 in this random-effects meta-analysis...
November 7, 2016: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/27813526/comparison-of-indocyanine-green-angiography-and-optical-coherence-tomographic-angiography-in-polypoidal-choroidal-vasculopathy
#11
K Takayama, Y Ito, H Kaneko, K Kataoka, T Sugita, R Maruko, K Hattori, E Ra, F Haga, H Terasaki
PurposeTo compare optical coherence tomographic angiography (OCTA) and indocyanine green angiography (ICGA) images for detecting polypoidal lesions (PLs) and branching vascular networks (BVNs), and to measure the polypoidal areas (PAs) in patients with polypoidal choroidal vasculopathy (PCV).MethodsAll patients underwent ICGA, optical coherence tomography (OCT), and OCTA. We compared the detection sensitivity for PL and BVN, as evaluated by the ICGA and OCTA images. Furthermore, PA measured by ICGA was divided into two groups: one in which the area could be measured by OCTA (ICGA(+)OCTA(+)) and the other in which the area could not be measured by OCTA (ICGA(+)OCTA(-))...
November 4, 2016: Eye
https://www.readbyqxmd.com/read/27810315/cost-effectiveness-analysis-of-pneumococcal-vaccination-for-infants-in-china
#12
Kristin A Maurer, Huey-Fen Chen, Abram L Wagner, Sonia T Hegde, Tejasi Patel, Matthew L Boulton, David W Hutton
BACKGROUND: Although China has a high burden of pneumococcal disease among young children, the government does not administer publicly-funded pneumococcal conjugate vaccines (PCV) through its Expanded Program on Immunization (EPI). We evaluated the cost-effectiveness of publicly-funded PCV-7, PCV-10, and PCV-13 vaccination programs for infants in China. METHODS: Using a Markov model, we simulated a cohort of 16 million Chinese infants to estimate the impact of PCV-7, PCV-10, and PCV-13 vaccination programs from a societal perspective...
December 7, 2016: Vaccine
https://www.readbyqxmd.com/read/27805727/reference-intervals-for-biochemical-blood-variables-packed-cell-volume-and-body-temperature-in-pet-rats-rattus-norvegicus-using-point-of-care-testing
#13
Anneleen Houtmeyers, Luc Duchateau, Bettina Grünewald, Katleen Hermans
BACKGROUND: Rats (Rattus norvegicus) are increasingly kept as pets, thus more and more requiring veterinary care. Important differences exist between pet and laboratory rats, but little information is available on pet rats. Diagnosis and treatment of pet rat diseases would benefit from RIs specific for this animal population. OBJECTIVES: The aim was to establish RIs for biochemical blood variables, PCV, and body temperature in pet rats. Additionally, influences of sex and feed rationing method (ad libitum, restricted) on these variables were determined...
November 2, 2016: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/27805246/bovine-neonatal-pancytopenia-correlation-between-clinical-symptoms-hematological-parameters-and-lifespan
#14
Marek Gehrke, Vivian Junge, Jędrzej M Jaśkowski, Mirosław P Polak, Krzysztof Urbaniak, Aleksandra Żuraw
OBJECTIVE: To compare the hematological parameters and clinical symptoms between Bovine Neonatal Pancytopenia (BNP) diseased calves dying before and after 14 days of life. MATERIAL AND METHODS: Clinical observations included 47 calves from dams which underwent a 3-year vaccination program with the inactivated PregSure(®) BVD vaccine. In 25 of these 47 BNP affected calves blood examinations were performed and in 22 dead calves diagnosis was mainly based on post-mortem findings...
November 2, 2016: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/27779169/comparison-of-the-1-year-outcomes-of-conbercept-therapy-between-two-different-angiographic-subtypes-of-polypoidal-choroidal-vasculopathy
#15
Yong Cheng, Xuan Shi, Jin-Feng Qu, Ming-Wei Zhao, Xiao-Xin Li
BACKGROUND: Polypoidal choroidal vasculopathy (PCV) is characterized by the presence of polyps with or without a branching vascular network and more prevalent among Asians. The aim of this study was to compare the outcomes of conbercept therapy between two different angiographic subtypes of PCV. METHODS: Fifty-eight patients of PCV were classified into two phenotypes according to indocyanine green angiography (ICGA). In Type 1, both feeder and draining vessels are visible on ICGA and network vessels are numerous...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27753771/cost-effectiveness-and-health-benefits-of-pediatric-23-valent-pneumococcal-polysaccharide-vaccine-7-valent-pneumococcal-conjugate-vaccine-and-forecasting-13-valent-pneumococcal-conjugate-vaccine-in-china
#16
Xiuting Mo, Ruoyan Gai Tobe, Xiaoyan Liu, Rintaro Mori
BACKGROUND: Each year in China, approximately 700,000 children under 5 years old are diagnosed with pneumonia, and 30,000 die of the disease. Although 7-valent pneumococcal conjugate vaccine (PCV-7) and 23-valent pneumococcal polysaccharide vaccine (PPV-23) are available in China, the costs are borne by the consumer, resulting in low coverage for PCV-7. We aimed to conduct a simulation study to assess the cost-effectiveness and health benefits of PCV-7, 13-valent pneumococcal conjugate vaccine (PCV-13) and PPV-23 to prevent childhood pneumonia and other vaccine-preventive diseases in China...
November 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27701767/hematologic-and-biochemical-reference-intervals-of-free-living-red-tailed-amazon-parrot-amazona-brasiliensis-nestlings-on-rasa-island-paran%C3%A3-brazil
#17
Frederico F Vaz, Rosangela Locatelli-Dittrich, Olair C Beltrame, Elenise A B Sipinski, Maria C Abbud, Rafael M Sezerban
BACKGROUND: The Red-Tailed Amazon parrot (Amazona brasiliensis) is an endangered species of the Psittaciformes. There is little information about hematologic and biochemical variables of this species. OBJECTIVES: The purpose of this study was to determine hematologic and biochemical RIs for free-living A brasiliensis nestlings on Rasa Island, Paraná, Brazil, and to compare the results between sexes. METHODS: Thirty-seven parrots were taken from their nests and physically restrained for clinical examination and blood collection...
October 4, 2016: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/27692770/effect-of-10-valent-pneumococcal-conjugate-vaccine-on-nasopharyngeal-carriage-of-streptococcus-pneumoniae-and-haemophilus-influenzae-among-children-in-s%C3%A3-o-paulo-brazil
#18
Maria-Cristina de C Brandileone, Rosemeire C Zanella, Samanta C G Almeida, Angela P Brandao, Ana F Ribeiro, Telma-Regina M P Carvalhanas, Helena Sato, Ana-Lúcia Andrade, Jennifer R Verani
In March 2010, Brazil introduced the 10-valent pneumococcal conjugate vaccine (PCV10) in the routine infant immunization program using a 4-dose schedule and catch-up for children <23months. We investigated PCV10 effect on nasopharyngeal carriage with vaccine-type Streptococcus pneumoniae (Spn) and non-typeable Haemophilus influenzae (NTHi) among children in São Paulo city. Cross-sectional surveys were conducted in 2010 (baseline) and 2013 (post-PCV10). Healthy PCV-naïve children aged 12-23months were recruited from primary health centers during immunization campaigns...
September 28, 2016: Vaccine
https://www.readbyqxmd.com/read/27687952/clinical-histopathological-and-metabolic-responses-following-exercise-in-arabian-horses-with-a-history-of-exertional-rhabdomyolysis
#19
E C McKenzie, L V Eyrich, M E Payton, S J Valberg
A previous report suggests a substantial incidence of exertional rhabdomyolysis (ER) in Arabian horses performing endurance racing. This study compared formalin histopathology and clinical and metabolic responses to a standardised field exercise test (SET) between Arabians with and without ER. Arabian horses with (n = 10; age 15.4 ± 5.6 years) and without (n = 9; 12.9 ± 6.1 years) prior ER were stall-rested for 24-48 h, after which paired ER and control horses were fitted with a telemetric ECG and performed a 47 min submaximal SET...
October 2016: Veterinary Journal
https://www.readbyqxmd.com/read/27652017/effect-of-different-levels-of-lepidium-sativum-l-on-growth-performance-carcass-characteristics-hematology-and-serum-biochemical-parameters-of-broilers
#20
Kassa Shawle, Mengistu Urge, Getachew Animut
BACKGROUND: Frequent use of antibiotics to stimulate growth and health of animals leads to the development of antibiotic-resistant populations of microorganisms. In this context, alternatives like herbs and spices to antibiotics are of importance, as they are natural products. Therefore, the present experiment was designed to evaluate the performance, carcass traits, hematology and serum biochemical parameters of broilers fed ration containing varying levels of Lepidium satvium (Garden cress) seed powder as feed additive up to the age of 42 days...
2016: SpringerPlus
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