Yutong Xia, Kuangqi Chen, Qianjie Yang, Zhitong Chen, Le Jin, Liyue Zhang, Xin Yu, Liyin Wang, Chen Xie, Yuan Zhao, Ye Shen, Jianping Tong
Corneal diseases are among the primary causes of blindness and vision loss worldwide. However, the pathogenesis of corneal diseases remains elusive, and diagnostic and therapeutic tools are limited. Thus, identifying new targets for the diagnosis and treatment of corneal diseases has gained great interest. Methylation, a type of epigenetic modification, modulates various cellular processes at both nucleic acid and protein levels. Growing evidence shows that methylation is a key regulator in the pathogenesis of corneal diseases, including inflammation, fibrosis, and neovascularization, making it an attractive potential therapeutic target...
April 8, 2024: Cell Death Discovery