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https://www.readbyqxmd.com/read/28227545/corticomuscular-coherence-variation-throughout-the-gait-cycle-during-overground-walking-and-ramp-ascent-a-preliminary-investigation
#1
Anna T Winslow, Justin Brantley, Fangshi Zhu, Jose L Contreras Vidal, He Huang, Anna T Winslow, Justin Brantley, Fangshi Zhu, Jose L Contreras Vidal, He Huang, Fangshi Zhu, Justin Brantley, Jose L Contreras Vidal, He Huang, Anna T Winslow
Recent designs of neural-machine interfaces (NMIs) incorporating electroencephalography (EEG) or electromyography (EMG) have been used in lower limb assistive devices. While the results of previous studies have shown promise, a NMI which takes advantage of early movement-related EEG activity preceding movement onset, as well as the improved signal-to-noise ratio of EMG, could prove to be more accurate and responsive than current NMI designs based solely on EEG or EMG. Previous studies have demonstrated that the activity of the sensorimotor cortex is coupled to the firing rate of motor units in lower limb muscles during voluntary contraction...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226429/postural-responses-after-utilization-of-a-computerized-biofeedback-based-intervention-aimed-at-improving-static-and-dynamic-balance-in-traumatic-brain-injury-a-case-study
#2
Rakesh Pilkar, Nibal Arzouni, Arvind Ramanujam, Kathleen Chervin, Karen J Nolan, Rakesh Pilkar, Nibal Arzouni, Arvind Ramanujam, Kathleen Chervin, Karen J Nolan, Arvind Ramanujam, Kathleen Chervin, Nibal Arzouni, Karen J Nolan, Rakesh Pilkar
Balance dysfunction is one of the most disabling aspects of Traumatic Brain Injury (TBI). Without rapid transmission and accurate perception of somatosensory inputs, the automatic postural responses required during standing may be delayed or absent after TBI which can lead to instability. Further, the sensitivity level to which environmental perturbations can be detected is also vital, as the central nervous system will only employ balance control strategies when it perceives a change in equilibrium. Such undetectable perturbations, however small they may be, can result in fatal falls, especially after TBI...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225843/-poverty-and-mental-disability-in-the-criminal-law-the-invisibles
#3
Ezequiel N Mercurio
In recent decades neuroscience research show the negative consequences of poverty in cognitive development. Environmental factors, such as material deprivation, exposure to stressful situations, violence, nutritional deprivation, environmental toxins may shape the developing brain. The changes of the structure and function of the brain since prenatal stages and their consequences can remain stable throughout the life cycle except early interventions are made. Research investigating have found significant link between child poverty and function and structural brain focusing on prefrontal cortex (i...
May 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28225842/-lopes-vs-brazil-case-psychiatry-and-international-human-rights-law-in-the-real-life
#4
Laura D Sobredo
In order to understand and adjust to the legal obligations that rule our professional practice as psychiatrists, it is useful to know the regulatory framework and its internal logic. The analysis of the case "Ximenes Lopes vs Brazil" (2006), from the Inter-American Court of Human Rights, intends to be, within this work, a contribution to understand those norms. The Inter-American Court of Human Rights conducts litigation that decides on the responsibility of Member States in alleged violations of human rights...
May 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28218340/world-health-organization-global-disability-action-plan-the-mongolian-perspective
#5
Fary Khan, Bhasker Amatya, Baljnnyam Avirmed, Yoon Kyoung Yi, Batchimeg Shirmen, Geoff Abbott, Mary P Galea
OBJECTIVE: To provide an update on disability and rehabilitation in Mongolia, and to identify potential barriers and facilitators for implementation of the World Health Organization (WHO) Global Disability Action Plan (GDAP). METHODS: A 4-member rehabilitation team from the Royal Melbourne Hospital conducted an intensive 6-day workshop at the Mongolian National University of Medical Sciences, for local healthcare professionals (n = 77) from medical rehabilitation facilities (urban/rural, public/private) and non-governmental organizations...
February 16, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28217871/secukinumab-in-active-rheumatoid-arthritis-a-randomized-double-blind-placebo-and-active-comparator-controlled-phase-3-study
#6
Francisco J Blanco, Rüdiger Möricke, Eva Dokoupilova, Christine Codding, Jeffrey Neal, Mats Andersson, Susanne Rohrer, Hanno Richards
OBJECTIVE: To evaluate the efficacy and safety of secukinumab in patients with active rheumatoid arthritis (RA) who had an inadequate response or intolerance to tumor necrosis factor inhibitors (TNF-inhibitors). METHODS: In this phase 3 study, 551 patients were randomized (1:1:1:1) to receive intravenous secukinumab 10 mg/kg (baseline, weeks 2, 4) followed by subcutaneous secukinumab 150 mg or 75 mg every 4 weeks or abatacept or placebo at the same dosing schedule...
February 19, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28216765/mental-health-mental-illness-and-human-rights-in-india-and-elsewhere-what-are-we-aiming-for
#7
REVIEW
Brendan D Kelly
The Mental Health Care Bill 2013 was introduced to the Rajya Sabha (India's upper house of parliament) in August 2013 and following 134 official amendments, passed in August 2016. Properly implemented, mental health legislation such as this plays a key role in protecting the rights of the mentally ill, ensuring access to care, and promoting social justice for the mentally ill, their families and carers. In this context, the 2006 United Nations' Convention on the Rights of Persons with Disabilities (CRPD) presents a real opportunity to improve the position of people with disabilities and those disabled by long-term mental illness...
December 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28211821/progressive-intervention-strategy-for-the-gait-of-sub-acute-stroke-patient-using-the-international-classification-of-functioning-disability-and-health-tool
#8
Tae-Woo Kang, Heon-Seok Cynn
BACKGROUND: The International Classification of Functioning, Disability, and Health (ICF) provides models for functions and disabilities. The ICF is presented as a frame that enables organizing physical therapists' clinical practice for application. OBJECTIVE: The purpose of the present study was to describe processes through which stroke patients are assessed and treated based on the ICF model. METHODS: The patient was a 65-year-old female diagnosed with right cerebral artery infarction with left hemiparesis...
February 15, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28208959/secondary-aneurysmal-bone-cyst-of-the-scapula-treated-by-ct-guided-percutaneous-polidocanol-injection-a-case-report
#9
Rahul Mohan, Gopakumar Thanuvan Sreekumaran
Aneurysmal Bone Cyst (ABC) is a rare benign tumour, usually affecting early age group and at the metaphysis of long bones. Scapular ABC's are even more rare, especially successfully treated cases. Standard treatment methods like curettage have high recurrence rates hence, adjuvant therapy may be required to avoid recurrence. Polidocanol sclerotherapy is becoming popular because of its safety and efficacy and is being tried successfully for both active as well as aggressive primary ABC of size 3-5cm. We used the same principle in a large secondary ABC of the scapula, which to the best of our knowledge has not been yet reported...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28202067/acupuncture-for-acute-moderate-thalamic-hemorrhage-randomized-controlled-trial-study-protocol
#10
RANDOMIZED CONTROLLED TRIAL
Chengwei Wang, Chao You, Lu Ma, Mengyue Liu, Meng Tian, Ning Li
BACKGROUND: Thalamic hemorrhage (TH) is a neurological insult with a high rate of morbidity and mortality. Moderate TH (10-30 ml) accounts for more than half of all TH. Treatment remains controversial. The role of acupuncture in patients with moderate TH is not clear. METHODS: We will conduct a single-center, randomized, parallel group, and assessor-blinded clinical trial. A total of 488 patients with moderate TH will be randomly assigned to one of eight groups: 10-15 cc left sided TH study group (N = 61) and a corresponding control group (N = 61), 10-15 cc right sided TH study group (N = 61) and a corresponding control group, 15-30 cc left sided TH study group (N = 61) and a corresponding control group (N = 61), and 15-30 cc right sided TH study group (N = 61) and a corresponding control group...
February 15, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28199782/social-independence-among-adult-congenital-heart-disease-patients-in-japan
#11
Ryota Ochiai, Yukitaka Ikeda, Hitoshi Kato, Isao Shiraishi
BACKGROUND: As treatment outcomes for congenital heart disease have improved, the social independence of adult congenital heart disease patients has become a key goal. We aimed to (1) determine the relationship between social independence and psychological profiles in these patients, and (2) identify patient anxieties, difficulties, and demands related to life in society. METHODS: A total of 143 patients aged ≥15 years who had physical disability certificates were selected using a questionnaire distributed by a patients association...
February 15, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28199737/inhibition-of-trpv1-confers-neuroprotection-reduces-tnf-%C3%AE-and-increases-il-10-in-a-rat-stroke-model
#12
Elham Hakimizadeh, Ali Shamsizadeh, Ali Roohbakhsh, Mohammad Kazemi Arababadi, Mohammad Reza Hajizadeh, Mehdi Shariati, Mohammad Reza Rahmani, Mohammad Allahtavakoli
Stroke is a major cause of mortality and long-term disability in adults. TRPV1 plays a crucial role in neuroinflammation. In the current study, the effects of TRPV1 agonist (capsaicin) and antagonist (AMG9810) on cerebral ischemia were investigated. Forty male Wistar rats were assigned to the following experimental groups: sham, vehicle) ischemic), AMG9810 (selective TRPV1 antagonist, 0.5 mg/kg; 3 h after stroke), and capsaicin (1 mg/kg; 3 h after stroke). Stroke was induced by permanent middle cerebral artery occlusion and neurological deficits were evaluated 1, 3, and 7 days after stroke...
February 15, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/28198067/verbal-spatial-iq-discrepancies-impact-brain-activation-associated-with-the-resolution-of-cognitive-conflict-in-children-and-adolescents
#13
Amy E Margolis, Katie S Davis, Lisa S Pao, Amy Lewis, Xiao Yang, Gregory Tau, Guihu Zhao, Zhishun Wang, Rachel Marsh
Verbal-spatial discrepancies are common in healthy individuals and in those with neurodevelopmental disorders associated with cognitive control deficits including: Autism Spectrum Disorder, Non-Verbal Learning Disability, Fragile X, 22q11 deletion, and Turner Syndrome. Previous data from healthy individuals suggest that the magnitude of the difference between verbal IQ (VIQ) and performance IQ (PIQ) scores (the VIQ>PIQ discrepancy) is associated with reduced thickness in frontal and parietal cortices (inferior frontal, anterior cingulate, inferior parietal lobule, and supramarginal gyrus) that support cognitive control...
February 15, 2017: Developmental Science
https://www.readbyqxmd.com/read/28196301/guinea-worm-infection-in-northern-nigeria-reflections-on-a-disease-approaching-eradication
#14
Brian Greenwood, Alice Greenwood, Andrew Bradley
Global eradication of the Guinea worm (Dracunculus medinensis) is near, although perhaps delayed a little by the discovery of a transmission cycle in dogs. It is, therefore, an appropriate time to reflect on the severe impact of this infection on the life of the communities where it was endemic prior to the start of the global eradication programme in 1981. From 1971-74, we conducted a series of unpublished studies on Guinea worm in a group of villages in Katsina State, northern Nigeria, where the infection was highly endemic...
February 14, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28185300/whole-body-vibration-training-as-a-workplace-based-sports-activity-for-employees-with-chronic-low-back-pain
#15
Tobias S Kaeding, Annika Karch, Rebecca Schwarz, Tatjana Flor, Torge-Christian Wittke, Momme Kück, Georg Böselt, Uwe Tegtbur, Lothar Stein
INTRODUCTION: The goal of this randomized and controlled study is to examine whether whole-body vibration (WBV) training is able to reduce back pain and physical disability in seated working office employees with chronic low-back pain in a real-world setting. MATERIALS AND METHODS: A total of 41 subjects (68.3% female/mean age 45.5 ± 9.1 years/mean BMI 26.6 ± 5.2) were randomly allocated to an intervention group (INT (n= 21)) or a control group (CON (n=20). The INT participated in WBV training 2...
February 10, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28178727/applying-ethical-and-legal-principles-to-new-technology-the-university-of-auckland-faculty-of-medical-and-health-sciences-policy-taking-and-sharing-images-of-patients
#16
Monique Jonas, Phillipa Malpas, Kate Kersey, Alan Merry, Warwick Bagg
AIMS: To develop a policy governing the taking and sharing of photographic and radiological images by medical students. METHODS: The Rules of the Health Information Privacy Code 1994 and the Code of Health and Disability Services Consumers' Rights were applied to the taking, storing and sharing of photographic and radiological images by medical students. Stakeholders, including clinicians, medical students, lawyers at district health boards in the Auckland region, the Office of the Privacy Commissioner and the Health and Disability Commissioner were consulted and their recommendations incorporated...
January 27, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28176578/student-life-how-to-choose-the-right-branch-of-nursing
#17
Kathy Oxtoby
If you are starting a career in nursing, one of the first things you need to consider is which branch to specialise in: adult, children, mental health or learning disabilities.
February 8, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28173619/hyperglycaemia-related-complications-at-the-time-of-diagnosis-can-cause-permanent-neurological-disability-in-children-with-neonatal-diabetes
#18
J O Day, S E Flanagan, M H Shepherd, A W Patrick, N Abid, L Torrens, A J Zeman, K A Patel, A T Hattersley
BACKGROUND: Children with neonatal diabetes often present with diabetic ketoacidosis and hence are at risk of cerebral oedema and subsequent long-term neurological deficits. These complications are difficult to identify because neurological features can also occur as a result of the specific genetic aetiology causing neonatal diabetes. CASE REPORTS: We report two cases of neonatal diabetes where ketoacidosis-related cerebral oedema was the major cause of their permanent neurological disability...
February 7, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28170120/physical-function-grip-strength-and-frailty-in-people-living-with-hiv-in-sub-saharan-africa-systematic-review
#19
REVIEW
Charlotte Bernard, François Dabis, Nathalie de Rekeneire
OBJECTIVE: To present the current knowledge on physical function, grip strength and frailty in HIV-infected patients living in sub-Saharan Africa, where the phenomenon is largely underestimated. METHODS: A systematic search was conducted on Medline, Scopus and African Index Medicus. We reviewed articles on sub-Saharan African people living with HIV (PLHIV) >18 years old, published until November 2016. RESULTS: Of 537 articles, 13 were conducted in six African countries and included in this review...
February 7, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28168521/does-apolipoprotein-a1-predict-microstructural-changes-in-subgenual-cingulum-in-early-parkinson
#20
Farzaneh Rahmani, Mohammad Hadi Aarabi
Higher plasma cholesterol levels are associated with lower Parkinson's disease (PD) risk. Apolipoprotein A-1 (ApoA-1) is a surface marker of brain HDL-like particles associated with the time of PD onset. Clinical correlates of serum Apolipoprotein A1 levels with structural brain connectivity in PD-related disorders remains unclear. Here, we applied a novel diffusion-weighted imaging approach [Diffusion Magnetic Resonance Imaging (MRI) Connectometry] to explore the association between ApoA-1 and structural brain connectivity in PD...
February 6, 2017: Journal of Neurology
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